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Search Results: 1 - 10 of 599671 matches for " C.A.;Metze "
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Immunoexpression of CD95 in chronic gastritis and gastric mucosa-associated lymphomas
Vassallo, J.;Godoy Jr., C.E.;Godoy, C.E.;Chagas, C.A.;Metze, K.;Trevisan, M.A.S.;
Brazilian Journal of Medical and Biological Research , 2004, DOI: 10.1590/S0100-879X2004000900015
Abstract: cd95 (fas/apo-1)-mediated apoptosis plays an important role in immunological regulation and is related to the pathogenesis of autoimmune diseases. immunoexpression of cd95 has been reported to frequently occur in low grade non-hodgkin lymphomas, especially of post-germinal center histogenesis, among which those originating in mucosa-associated lymphoid tissue (malt lymphomas). however, there is no report comparing in situ immunoexpression of this marker in lymphomas and the hyperplastic lymphoid reaction (chronic gastritis) related to helicobacter pylori infection. the purpose of the present research was to compare the intensity of lymphoid cd95 immunoexpression in 15 cases of h. pylori-related chronic gastritis and 15 gastric malt lymphomas. cd95 (anti-cd95) was detected by an immunoperoxidase technique in paraffin sections using the catalyzed amplification system. graduation of reaction intensity (percentage of cd95-positive cells) was semiquantitative, from 1+ to 4+. nine cases of chronic gastritis were 4+, five 2+ and one 1+. three lymphomas were 4+, three 3+, four 2+, four 1+, and one was negative. although 14 of 15 lymphomas were positive for cd95, the intensity of the reaction was significantly weaker compared to that obtained with gastric tissue for patients with gastritis (p = 0.03). the difference in cd95 immunoexpression does not seem to be useful as an isolated criterion in the differential diagnosis between chronic gastritis and malt lymphomas since there was overlapping of immunostaining patterns. however, it suggests the possibility of a pathogenetic role of this apoptosis-regulating protein in malt lymphomas.
Models of the electroreduction of passive layers on cobalt
Gervasi, C.A.;
Journal of the Brazilian Chemical Society , 1997, DOI: 10.1590/S0103-50531997000200015
Abstract: potentiostatic current transient techniques were employed to study the electroreduction process of surface layers formed on polycrystalline cobalt in carbonate-bicarbonate ion-containing solutions. the dynamic system analysis performed using parametric identification procedures and non-linear fit routines demonstrated that data obtained under a wide variety of experimental conditions may be interpreted by taking into account the participation of various co(ii)/co(iii)-containing surface species. the influence of the anodizing time at the potential of oxide film formation may be discussed on the basis of the proposed electroreduction models.
Insights into the role of hydration in protein structure and stability obtained through hydrostatic pressure studies
Royer, C.A.;
Brazilian Journal of Medical and Biological Research , 2005, DOI: 10.1590/S0100-879X2005000800003
Abstract: a thorough understanding of protein structure and stability requires that we elucidate the molecular basis for the effects of both temperature and pressure on protein conformational transitions. while temperature effects are relatively well understood and the change in heat capacity upon unfolding has been reasonably well parameterized, the state of understanding of pressure effects is much less advanced. ultimately, a quantitative parameterization of the volume changes (at the basis of pressure effects) accompanying protein conformational transitions will be required. the present report introduces a qualitative hypothesis based on available model compound data for the molecular basis of volume change upon protein unfolding and its dependence on temperature.
JAK/STAT-deficient cell lines
Bonjardim, C.A.;
Brazilian Journal of Medical and Biological Research , 1998, DOI: 10.1590/S0100-879X1998001100004
Abstract: mutant cell lines b3 and b10, which are unresponsive to both interferon (ifn)-a and ifn-g, and line b9, which does not respond to ifn-g stimulation, are described. the mutants were submitted to fluorescence-activated cell sorting (facs) from a cellular pool, which was obtained from the parental cell line 2c4 after several rounds of mutagenesis. the unresponsiveness to ifn stimulation was observed both in terms of expression of cell surface markers (cd2, class i and ii hlas) and mrna expression of ifn-stimulated genes (2'-5' oligoadenylate synthetase (oas), 9-27, and guanylate binding protein (gbp)). genetic crossing of b3, b9 and b10 with u3 (stat1-), g2a (jak2-) and u4 (jak1-) mutants, respectively, did not restore ifn responsiveness to the hybrid cell lines. however, when these cell lines were crossed with the same mutants, but using the pairwise crosses b3 x u4, b9 x u3 and b10 x u3, the cell hybrids recovered full ifn responsiveness. the present genetic experiments permitted us to assign the mutant cell lines b3, b9 and b10 to the u3, g2 and u4 complementation groups, respectively. these conclusions were supported by the analysis of ifn-stimulated genes in the mutants.
CT&F - Ciencia, Tecnología y Futuro , 1998,
Abstract: high-resolution mass spectrometry-gas chromatography is combined with the hc22 method in order to obtain a detailed information about the chemical composition of diesel and the distribution of different compound types in terms of its final boiling temperature from a single analysis. the total time elapsed from sample injection and signal processing to obtain final results is 90 minutes. this fact makes this methodology a new and very important tool for the decision making process concerning the most suitable final boiling temperature and the type of treatment of the product in order to obtain diesel that fulfills the international standards. the consistency and repeatability of the experimental results are demonstrated.
Temperature effect on CARBON biomass in soils FROM TROPICAL AND TEMPERATE REGIONS
Vasconcellos, C.A.;
Scientia Agricola , 1998, DOI: 10.1590/S0103-90161998000100016
Abstract: four soils from various origins, (tropical and temperate regions) were amended with 14c labelled glucose (1mg c.g-1 soil) and incubated at 15oc and 35oc to determine the temperature effect on the carbon turnover and on the microbial biomass. the temperature effect on the biomass increased with the glucose addition. the biomass mineralization rates were higher at 35oc than at 15oc and higher for woburn and pegwell soils (temperate region) than for capinopolis and janauba (tropical region). specific respiration rate (srr) of new biomass (from glucose) and old biomass showed different behaviors between soils. at 15oc, the turnover c was 207, 225, 115 and 141 days for janauba, capinopolis, woburn and pegwell soil, respectively. at 35oc, it was 92, 69, 69 and 33 days for the same soils. the residual 14c in the soil was higher at 35oc. the final total biomasses at 15oc and 35oc were correlated with the initial soil carbon content. there was an average of 31 and 8 mg of biomass c.g-1 soil organic carbon, respectively at 15oc and 35oc. the initial carbon content was an important factor to explain the mineralization rate at 35oc.
Evaluation of Rabbit Breeds and Crosses for Pre-Weaning Reproductive Performance In Humid Tropics
Chineke, C.A
Journal of Animal and Veterinary Advances , 2012,
Abstract: Pre-weaning data on 466 kits from 109 litters, 280 kits from 78 litters and 261kits from 74 litters at birth, 21 and 28 days of age respectively were collected over 3years (1998- 2001). The litters representing 8 genotypes namely New Zealand white x New Zealand white (NZW x NZW) and Chinchilla x Chinchilla (CHA x CHA) purebreds; and New Zealand white x Chinchilla (NZW x CHA), New Zealand white Dutch belted x New Zealand white Dutch belted (NZWDBD x NZWDBD), New Zealand white x New Zealand white Dutch belted (NZW x NZWDBD), New Zealand white Croel x New Zealand white Croel (NZW CRL x NZW CRL), Chinchilla x New Zealand white Dutch Belted (CHA x NZWDBD) and Chinchilla x New Zealand white Croel (CHA x NZW CRL) crossbreds were assessed for effect of genotype, parity of dam, litter size, sex and season of birth on Individual Kit weight (IKT), Litter Weight (LWT) average Litter Weight (LWT) and Litter Size (LTZ) at birth, 21 and 28 days. The analytical results showed that genotype, litter size, parity, sex and season were important sources of variation for performance characteristics studied. Crossbred NZW x CHA and NZWDBD x NZWDBD individual kit weights at birth and 28 day were comparable (p>0.05). NZW- CHA kits were significantly heavier in ALT at birth and 21 days (p<0.05). NZWDBD x NZWDBD kit weighed more in LWT (P<0.05) and recorded larger litter size (p<0.05) at all ages than other genotypes IKT and ALT consistently in creased with litter size at all ages. All traits considered in this study at various ages were inconsistent with parity. The litters born in wet season maintained superior body weights over dry season litters. The sex mean for IKT at 21 day was significantly different (p<0.05) with females weighing more than males. The results of this study indicate that choice of breeds for commercial production should be based on pre-weaning performance. In addition genotype, litter size, parity, sex and season as important sources of variation should be considered in improvement programme to increase meat yield from rabbit breeds and crosses. Furthermore, this study provides corroborative evidence in support of the adoption of cross breeding in the commercial rabbit industry in the humid tropics.
Global Relative Controlability for Nonlinear Neutral Systems with Delays in the Control
C.A. Nse
Research Journal of Applied Sciences , 2012,
Abstract: Sufficient conditions for global relative controllability of certain types of nonlinear neutral time-varying systems with time-variable delay in the control are given. By a careful linearisation of our system, the results are obtained by use of Schauder s fixed-point theorem and a generalization of Davison.
Studies of Pre-Weaning Physical Measurements in Rabbits in Humid Tropics of Nigeria
Chineke, C.A
Journal of Animal and Veterinary Advances , 2012,
Abstract: Pre-weaning linear measurements on 280 and 261 kits from 78 and 74 litters at 21 and 28 days of age, collected over 3 years were used in the study. Evaluation criteria include nose to shoulder length(NTS), Shoulder To Tail (STL), trunk length (TLK), heart girth (HGT), height at withers (HTW) and length of ear (LTE).The least squares model included main effects of genotype, parity, sex, season, first-order interactions between genotype,sex, parity and season and random error. Genotype, parity, sex and season differences were detected for linear traits considered. Crossbred New Zealand white x Chinchilla (NZW xCHA) and New Zealand white. Dutch-belted x New Zealand white. Dutch-belted (NZWDBDxNZWDBD) had best performance over the other genotypes. Parity means were significantly (p<0.05) different for all traits except 21-day HGT. Parity 6 was superior in 21-day linear traits and in 28- NTS and STL. Sex mean values for 21-day linear measurements were different (p<0.05) except HGT with females being consistently bigger and longer than males. Sex means were similar at 28 days where females recorded longer STL and HWT and wider HGT than males. The mean values by season differed (p<0.05) in 21-day NTS, STL and TKL and in 28-day measurements except LTE. Dry season measurements were superior at 28 days. The linear body measurements would provide quantitative measures of body size and shape. Assure factors influencing them should be given attention in breeding programmes
The Relationships among Body Weights and Linear Dimensions in Rabbit Breeds and Crosses
C.A. Chineke
Journal of Animal and Veterinary Advances , 2012,
Abstract: A breeding experiment was conducted to assess the relationships among body weights and linear body measurements in rabbit breeds and crosses. Data on 259 and 215 kits from 73 and 62 litters at 35 and 56 weaning and post- weaning ages respectively were used in the study. The litters representing 8 genotypes evolved from random mating involving 49 does and 13 bucks. The traits measured were body Weights (BWT ), Nose to Shoulder Length ( NTS ), Shoulder to Tail Length ( STL ), Trunk Length ( TKL ), heart girth ( HGT), height at withers ( HTW ) and length of ear. Measurements of the body components for each genotype were regressed against live weight at 35 and 56 days of age using linear and non-linear (exponential and polynomial) regression analyses. The relationship between live weight and each of the measurement were also assessed. The regression equations, estimates of parameters and coefficients of determination ( R ) for the fitted functions were determined. Body measurements and weight were generally positive and significant (p < 0.001) demonstrating strong inter-relationship among the variables. The coefficient of determination varied from 5.27 to 90.3 and from 0.090 to 90.6 at 35 and 56 days respectively. Based on R , polynomial function was superior in terms of goodness of fit to the data and its ability to predict. Body weight was better predicted using STL of genotype NZWDBD x NZWDBD at both ages.
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