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Search Results: 1 - 10 of 21009 matches for " Byung-Ok Kim "
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Evaluation of Methane Yield on Mesophilic-Dry Anaerobic Digestion of Piggery Manure Mixed with Chaff for Agricultural Area  [PDF]
Dong-Heui Kwak, Mi-Sug Kim, Jae-Seung Kim, Young-Youl Oh, Soon-Ok Noh, Byung-Ok So, Su-Young Jung, Su-Jin Jung, Soo-Wan Chae
Advances in Chemical Engineering and Science (ACES) , 2013, DOI: 10.4236/aces.2013.34029
Abstract: A mesophilic-dry anaerobic digestion process is valid in treating high-concentration substrates containing low moisture content. It has merits of lower wastewater discharge and lower heat capacity required in maintaining reactor temperature as compared with a thermophilic-wet anaerobic digestion process. In fact, chaff can be easily obtained in farming areas and used as a mixture substrate as one of bulking agents for controlling moisture and supplying carbon. For this reason, this study applies the chaff to improve livestock manure, which contains high moisture content and is discharged from domestic pig farms. This study aims at verifying its feasibility for improving methane production efficiency on a basis of BMP (Biochemical Methane Potential) assay obtained through a series of experiments. Finding results were methane gas production and gas production per volatile solid (VS) added, and methane gas production among biogas production were increased as the chaff added in the piggery manure was increased. According to experimental results for improving the methane production efficiency, mixture of the chaff and the piggery manure played an important role in controlling the moisture content and improving the methane gas production rate, and also verified its feasibility in the mesophilic-dry anaerobic digestion process indicating relatively less difficulty for operation and management.
Comprehensive Analysis to Improve the Validation Rate for Single Nucleotide Variants Detected by Next-Generation Sequencing
Mi-Hyun Park, Hwanseok Rhee, Jung Hoon Park, Hae-Mi Woo, Byung-Ok Choi, Bo-Young Kim, Ki Wha Chung, Yoo-Bok Cho, Hyung Jin Kim, Ji-Won Jung, Soo Kyung Koo
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0086664
Abstract: Next-generation sequencing (NGS) has enabled the high-throughput discovery of germline and somatic mutations. However, NGS-based variant detection is still prone to errors, resulting in inaccurate variant calls. Here, we categorized the variants detected by NGS according to total read depth (TD) and SNP quality (SNPQ), and performed Sanger sequencing with 348 selected non-synonymous single nucleotide variants (SNVs) for validation. Using the SAMtools and GATK algorithms, the validation rate was positively correlated with SNPQ but showed no correlation with TD. In addition, common variants called by both programs had a higher validation rate than caller-specific variants. We further examined several parameters to improve the validation rate, and found that strand bias (SB) was a key parameter. SB in NGS data showed a strong difference between the variants passing validation and those that failed validation, showing a validation rate of more than 92% (filtering cutoff value: alternate allele forward [AF]≥20 and AF<80 in SAMtools, SB<–10 in GATK). Moreover, the validation rate increased significantly (up to 97–99%) when the variant was filtered together with the suggested values of mapping quality (MQ), SNPQ and SB. This detailed and systematic study provides comprehensive recommendations for improving validation rates, saving time and lowering cost in NGS analyses.
Efficacies of the new Paclitaxel-eluting Coroflex Please? Stent in percutaneous coronary intervention; comparison of efficacy between Coroflex Please? and Taxus? (ECO-PLEASANT) trial: study rationale and design
Jae-Bin Seo, Hui-Kyung Jeon, Kyung-Woo Park, Jong-Seon Park, Jang-Ho Bae, Sang-Wook Kim, Keon-Woong Moon, Jae-Woong Choi, Sang-Gon Lee, Woo-Young Chung, Tae-Jin Youn, Soo-Joong Kim, Doo-Il Kim, Byung-Ok Kim, Min-Su Hyon, Keum-Soo Park, Tae-Joon Cha, Hweung-Kon Hwang, Seung-Ho Hur, Hyo-Soo Kim
Trials , 2009, DOI: 10.1186/1745-6215-10-98
Abstract: In the comparison of Efficacy between COroflex PLEASe? ANd Taxus? stent(ECO-PLEASANT) trial, approximately 900 patients are being prospectively and randomly assigned to the either type of Coroflex Please? stent and Taxus Liberte? stent via web-based randomization. The primary endpoint is clinically driven target vessel revascularization at 9 months. The secondary endpoints include major cardiac adverse events, target vessel failure, stent thrombosis and angiographic efficacy endpoints.The ECO-PLEASANT trial is the study not yet performed to directly compare the efficacy and safety of the Coroflex Please? versus Taxus Liberte? stent. On the basis of this trial, we will be able to find out whether the Coroflex Please? stent is non-inferior to Taxus Liberte? stent or not.ClinicalTrials.gov number, NCT00699543.Previous randomized trials have shown the efficacy of a slow-release polymeric sirolimus-eluting stent (Cypher?, Cordis, Warren, NJ, USA), paclitaxel-eluting stent (Taxus?, Boston Scientific, Natick, MA, USA), and zotarolimus-eluting stent (Endeavor?, Medtronic, Minneapolis, MN, USA) over bare metal stents in reducing neointimal hyperplasia, late luminal loss, and angiographic restenosis leading to decreased target lesion revascularization [1-11] The Paclitaxel-eluting Coroflex Please? stent is a newly developed drug eluting stent using the Coroflex? stent platform combined with the drug paclitaxel contained in a polymer coating[12]In the PECOPS I, which was one-arm observational study, the results of Coroflex Please? stent were within the range of other Paclitaxel-eluting coronary stents [12,13] Compared with binary restenosis rate of 7.9% in Taxus IV trial, Coroflex? Please stent showed 7.8% of restenosis rate[7] The 3.1% of 30 day MACE rate is within the range of other trials with stents eluting Paclitaxel or Sirolimus. The 6 month MACE rates in PECOPS I were 8.0%, which was similar to 7.8%, and 8.5% in Taxus II MR and SR, respectively[6] In Taxus IV, 9 month f
Transparent (1–x)TiO2–xFe2O3 (x = 0, 5, 10, 15 and 20 mol%) thin films prepared by sol-gel process
Kyu-Seog HWANG,Young-Sun JEON,Kyung-Ok JEON,Byung-Hoon KIM
Optica Applicata , 2005,
Abstract: Transparent iron-doped titanium oxide thin films were prepared on soda-lime-silica glass substrate from a titanium naphthenate precursor. Films prefired at 500°C for 10 min were finally annealed at 500°C for 30 min in air. Field emission–scanning electron microscope and scanning probe microscope were used for characterizing the surface structure of the film. A sharp absorption edge of the film was observed. The film containing iron showed a shift towards the visible in the absorption threshold.
The Effect of Smartwork Environment on Organizational Commitment and Innovative Behavior in the Global Financial Service Industry  [PDF]
Myong Ok Kim, Sooyeon Shin
Journal of Service Science and Management (JSSM) , 2015, DOI: 10.4236/jssm.2015.81014
Abstract: This study analyzed how smartwork environment perceived by employees in global financial service industry (GFSI) influences their organizational commitment and innovative behavior. Data were collected through a questionnaire survey from 147 respondents randomly selected from seven global financial service firms in Seoul, Korea, where all three types of smartwork setting (working at home, mobile office, and smartwork center) are utilized. We found that no specific characteristic of smartwork environment (presenteeism, IT complexity, security risks, task interdependence) was significantly related to organizational commitment. For innovative behavior, only IT complexity and security risks of smartwork environment appeared to be significantly related. Contrary to our expectations, it was found that the negative emotion and stress of employees as to the complexity of IC technology and IT security risks can actually inspire their innovative behavior.
TTF-1 Action on the Transcriptional Regulation of Cyclooxygenase-2 Gene in the Rat Brain
Chang Ho Yun, Jae Geun Kim, Byong Seo Park, Hye Myeong Lee, Dong Hee Kim, Eun Ok Kim, Joong Jean Park, Jeong Woo Park, Giuseppe Damante, Young Il Kim, Byung Ju Lee
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0028959
Abstract: We have recently found that thyroid transcription factor-1 (TTF-1), a homeodomain-containing transcription factor, is postnatally expressed in discrete areas of the hypothalamus and closely involved in neuroendocrine functions. We now report that transcription of cyclooxygenase-2 (COX-2), the rate limiting enzyme in prostaglandin biosynthesis, was inhibited by TTF-1. Double immunohistochemistry demonstrated that TTF-1 was expressed in the astrocytes and endothelial cells of blood vessel in the hypothalamus. Promoter assays and electrophoretic mobility shift assays showed that TTF-1 inhibited COX-2 transcription by binding to specific binding domains in the COX-2 promoter. Furthermore, blocking TTF-1 synthesis by intracerebroventricular injection of an antisense oligomer induced an increase of COX-2 synthesis in non-neuronal cells of the rat hypothalamus, and resulted in animals' hyperthermia. These results suggest that TTF-1 is physiologically involved in the control of thermogenesis by regulating COX-2 transcription in the brain.
Quantile regression with varying coefficients
Mi-Ok Kim
Mathematics , 2007, DOI: 10.1214/009053606000000966
Abstract: Quantile regression provides a framework for modeling statistical quantities of interest other than the conditional mean. The regression methodology is well developed for linear models, but less so for nonparametric models. We consider conditional quantiles with varying coefficients and propose a methodology for their estimation and assessment using polynomial splines. The proposed estimators are easy to compute via standard quantile regression algorithms and a stepwise knot selection algorithm. The proposed Rao-score-type test that assesses the model against a linear model is also easy to implement. We provide asymptotic results on the convergence of the estimators and the null distribution of the test statistic. Empirical results are also provided, including an application of the methodology to forced expiratory volume (FEV) data.
Dynamic choosability of triangle-free graphs and sparse random graphs
Jaehoon Kim,Seongmin Ok
Mathematics , 2015,
Abstract: The \textit{$r$-dynamic choosability} of a graph $G$, written ${\rm ch}_r(G)$, is the least $k$ such that whenever each vertex is assigned a list of at least $k$ colors a proper coloring can be chosen from the lists so that every vertex $v$ has at least $\min\{d_G(v),r\}$ neighbors of distinct colors. Let ${\rm ch}(G)$ denote the choice number of $G$. In this paper, we prove ${\rm ch}_r(G)\leq (1+o(1)){\rm ch}(G)$ when $\frac{\Delta(G)}{\delta(G)}$ is bounded. We also show that there exists a constant $C$ such that for the random graph $G=G(n,p)$ with $\frac{2}{n}
Isolation and Characterization of Volatile Organic Compounds-Degrading Bacillus Strains from Loess  [PDF]
Soo Yeon Lee, Hye Yun Oh, Ok Bin Kim
Journal of Environmental Protection (JEP) , 2013, DOI: 10.4236/jep.2013.44A007
Abstract:

Volatile organic compounds (VOCs) are harmful to human health and the environment. Recently, loess (Hwangtoh) was used as an eco-friendly interior paint formulation in Korea. It is used even more commonly as a filter carrier to remove VOCs. In this study, we isolated Bacillus strains from a loess filter. The strains that were tolerant to VOCs were labeled according to the series VOC01 to VOC35. Four strains—VOC03, VOC11, VOC18, and VOC30—were investigated for their ability to degrade cyclohexane and toluene. Strain VOC18 best degraded both VOCs, whereas VOC03 demonstrated no ability to degrade VOCs. In keeping with this, VOC18 grew best on cyclohexane or toluene as the sole carbon source. The strains were identified by their physiochemical and phylogenetic characteristics. Strain VOC18 was determined as a strain of Bacillus cereus; VOC11 and VOC30 were determined as differentiated strains of B. thuringiensis. Strain VOC03, which demonstrated high tolerance but no ability to degrade VOCs, was identified as a strain of B. megaterium.

Buffon’s Needle Algorithm to Estimate π  [PDF]
Chi-Ok Hwang, Yeongwon Kim, Cheolgi Im, Sunggeun Lee
Applied Mathematics (AM) , 2017, DOI: 10.4236/am.2017.83022
Abstract: Buffon’s needle experiment was originally devised to get the value of π. With the advent of computers, Buffon’s needle algorithm has been used pedagogically as an example of Monte Carlo methods in introduction classes, and there are many Buffon’s needle algorithm implementations available on the internet. However, for the calculation of π, the exact value of π is used in the programs for Buffon’s needle angle sampling, and hence the example is not demonstrated correctly. This brief note presents a random angle sampling algorithm for the Buffon’s needle. We then compare the Buffon’s needle and Hit-and-Miss integration algorithms using Monte Carlo laboriousness comparison, and find that the Hit-and-Miss algorithm is superior.
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