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Search Results: 1 - 10 of 8157 matches for " Bruno Tengang "
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Epidemiology, Clinical and Paraclinical Presentations of Pulmonary Embolism: A Cross-Sectional Study in a Sub-Saharan Africa Setting  [PDF]
Bertrand Hugo Mbatchou Ngahane, Félicité Kamdem, Silvain Raoul Simeni Njonnou, Nina Chebou, Anastase Dzudie, Serge Arnold Ebongue, Bruno Tengang, Fernando Kemta Lekpa, Yacouba Mapoure Njankouo, Sidick Mouliom, Henri Roger Ngote, Henry Luma Namme
Open Journal of Respiratory Diseases (OJRD) , 2019, DOI: 10.4236/ojrd.2019.93008
Abstract: Background: Venous thromboembolic (VTE) disease burden is increasing worldwide, representing a major cause of cardiovascular death and public health problem. Pulmonary embolism (PE) is the most serious clinical presentation of VTE. Epidemiological and clinical data on PE are still lacking in Africa, particularly in Cameroon. This study aimed at determining the clinical features as well as imaging presentation and outcome of pulmonary embolism. Methods: A cross-sectional study was carried out in three hospitals in Douala. We retrospectively reviewed patient records admitted for PE from January 2009 to May 2017. We collected data on epidemiology, clinical presentation, venous Doppler/pulmonary computed tomographic angiography (CTA), and outcome. Results: We included 103 patients (56 males) with PE. Their median age was 52 years. The main risk factors were obesity (49.5%), hypertension (35.0%), long trip (24.3%) and cancer (18.4%). The most frequent clinical presentations were dyspnoea (83.4%), chest pain (78.6%), and cough (40.8%). Additionally, pleural effusion (32.8%), atelectasis (25.7%) and pulmonary hyperlucency (20.0%) were the most frequent findings on chest X-ray. The main abnormalities found in electrocardiogram were sinus tachycardia (63.4%), S1Q3T3 aspect (37.6%) and right axial deviation (28.7%). Moreover, right cavities dilatation (26.0%), pulmonary artery hypertension (35.0%) and pulmonary artery dilatation (21.0%) were the main echocardiographic findings. Low-molecular-weight heparin (LMWH) was the initial anticoagulant in all cases. There were 19 (18.4%) in-hospital deaths, and the mean hospital stay was 8.5 ± 5 days. Conclusion: PE is not rare in our setting. Obesity, long trip and cancer are the main risk factors, while dyspnoea, chest pain and respiratory distress are the main clinical presentation for PE. LMWH remains the therapeutic agent of choice. Lastly, in-hospital mortality is very high.
Harmonizing Budgeting and Accounting: The Case of Italy  [PDF]
Adriana Bruno
Open Journal of Accounting (OJAcct) , 2014, DOI: 10.4236/ojacct.2014.31005
Abstract: Many reforms have been undertaken in recent years; indeed, scholars have concentrated their attention on ac-counting techniques, financial management, and the potential for adding tools to support managerial reform agendas [1-3]. This paper extends prior research by focusing on the manner of diffusion ongoing reform process, through the adoption of the new version of Financial Management Reform process model [3]. The objective of this research is to investigate how a new accounting system has been introduced in the public sector in a processual and outcome-oriented analysis [4]. The study setting for this research is the Italian government, specifically the intermediate or regional level government, Campania Region, where a trial period is underway. The objective is to discover what obstacles and difficulties might exist when implementing a harmonized accounting and budgeting system while moving toward an accrual accounting system. The study reveals the main paradox in the implementation of the reform. This kind of study could add fresh knowledge to the literature and highlight common problems encountered when implementing accounting reforms. Additionally it could help set a standard to assist public entities in developing and implementing accounting guidelines.
A Few Reflections on the Reasons Why Cooperative Firms Have Failed to Gain a Firm Foothold  [PDF]
Bruno Jossa
Open Journal of Business and Management (OJBM) , 2015, DOI: 10.4236/ojbm.2015.33027
Abstract: After the inception of the cooperative movement in the mid-19th century, it was widely held that capitalistic businesses would soon be replaced by a system of worker-controlled firms and a wealth of policy proposals called for a major impulse to cooperation in later years also. But cooperation has not met with the hoped-for success. How do we account for this? To our day, employee management specialists have been unable to provide a satisfactory explanation for the fact that the policy proposal to introduce democratic firm control still carries little consensus despite the collapse of the Soviet model of communism. In this paper, we give some answers to the question and emphasise the idea that progress in the direction of a generalised system of cooperative firms would amount to a considerable improvement over capitalism, but will hardly be made without the effective contribution of intellectuals and political parties.
Competition in a Democratic Firm System: Failures and Constraints  [PDF]
Bruno Jossa
Modern Economy (ME) , 2017, DOI: 10.4236/me.2017.811092
Abstract: Considering that businesses face bankruptcy when their aggregate costs exceed their revenues, the cancellation of the largest production cost item—wages and salaries—in an employee-managed firm system is an effective safeguard against bankruptcy. For this and other reasons, the author argues that risks of insolvency are unlikely to scare democratic firms into accepting the capitalistic logic of cut-throat competition.
The True Strong Point of Democratic Firm Management  [PDF]
Bruno Jossa
Modern Economy (ME) , 2018, DOI: 10.4236/me.2018.910101
Abstract: According to the author, the benefits society would derive from the transfer of corporate decision powers to workers upon the establishment of a democratic firm system include both the disempowerment of capitalists and, most importantly, a powerful impetus in the direction of full democracy. Capitalism is a despotic system enabling capitalists to impose their laws not only on workers, but even on politics and culture has been gaining wide currency. Therefore, one major advantage of democratic firm management is the enforcement of the “one head, one vote” principle in lieu of the “one share, one vote” criterion.
Effects of omacor® on left ventricular remodelling consecutive to post myocardial infarction special issue-myocardial infarction  [PDF]
Bruno Le Grand
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.35A007
Abstract: Ventricular remodelling is the main trigger of the development of heart failure. Therefore, the reduction of structural remodelling is known to prevent the development of heart failure. The aim of the present study was to investigate the effects of OMACOR?, a well known mixture of EPA and DHA in an experimental model of heart failure induced by occlusion of left descending coronary artery and the reperfusion within 2 months. After a long term treatment of 2 months; OMACOR? (100 mg/kg) statistically significantly reduced the expansion of infarcted zone (35% ± 4%, P < 0.05, n = 9, versus 45% ± 3% in the vehicle group). The phosphorylation of Cx43 as biomarker of the cardiac remodelling was visualised by immunofluorescence in rat’s heart at the end of the study. In the vehicle-infarcted group, a significant de-phosphorylation of Cx43 was observed (8.2 ± 1.0 u.a, n = 8 compared to 11.8 ± 1.3 u.a in the sham group, n = 9) confirming a remodelling process in the infarcted group. In the group treated with OMACOR?,the de-phosphorylation of Cx43 was no longer observed compared to the sham group (16.4 ± 2.9 u.a, n = 9, NS). The present results demonstrate that a long term treatment with OMA-COR? reduced the infarcted size in experimental models of heart failure and that these anti-remodelling effects are due at least in part by resynchronizing the gap junction activity.


World Trade Logics and Measure of Global Inequality: Regional Pattern and Globalization Evolution between 2003-2012  [PDF]
Bruno G. Rüttimann
Open Journal of Applied Sciences (OJAppS) , 2014, DOI: 10.4236/ojapps.2014.44019
Abstract: The economy is globalizing. But how are the different economic world regions performing regarding globalization of trade flows? Why are they performing differently? Globalization is not only the increase of international trade between certain preferential geographic areas of economy, but also the resulting increase of interweavement of trade flows between different geographical areas, independent of the amount of trade. This paper is a revised and expanded version of the paper entitled “World Trade and Associated Systems Risk of Global Inequality: Empiric Study of Globalization Evolution between 2003-2011 and Regional Pattern Analysis” presented at International Conference on Applied Economics (ICOAE2013), Istanbul, 27-29 June, 2013. This paper analyzes the evolution of world trade flows between 2003-2012 and performs a cross-section analysis of the year 2012. The economic interweavement will be measured by an inequality risk metric applied to the supply-demand matrix. This risk indicator is based on the concept of statistical entropy resulting in an inequality risk measure, giving an indication for the degree of economic globalization and the evolution of globalization in different geographical regions. In addition, it analyses the governing rational of globalization evolution. The result of this research shows that economic trade flows are globalizing, but with clear different regional patterns, not only between globalizing and de-globalizing regions, but also within the globalizing and de-globalizing regions itself. The emerging economies such as China or the Middle East are globalizing whereas mature economies such as North America and Europe are de-globalizing, confirming for globalization of the inverse Kuznets evolution. The different patterns between the different economic world regions can be explained by using the Globalization Type’s Model as well as the Central Theorem of Globalization.
Discourse about Linear Programming and Lean Manufacturing: Two Different Approaches with a Similar, Converging Rational  [PDF]
Bruno G. Rüttimann
Journal of Service Science and Management (JSSM) , 2015, DOI: 10.4236/jssm.2015.81010
Abstract: In recent years, the Toyota Production System has also assumed in western manufacturing plants a predominant position. Lean Manufacturing, as it is usually called in the occidental world, aims at a “Single-piece-flow” job handling and has its advantages compared to the classic “Batch and Queue” job handling. On the other hand, mathematical Linear Programming optimization techniques have passed into oblivion, having obtained the feel to be inappropriate for production planning. Although the two approaches have different aims and application, they give particular attention to scarce resources. The concepts of “bottleneck” in Lean Manufacturing and “shadow price” in Linear Programming are complementary. The paper shows the different focus of the two approaches and crystallizes their synergic values.
Structure Sorting of Multiple Macromolecular States in Heterogeneous Cryo-EM Samples by 3D Multivariate Statistical Analysis  [PDF]
Bruno P. Klaholz
Open Journal of Statistics (OJS) , 2015, DOI: 10.4236/ojs.2015.57081
Abstract:

Heterogeneity of biological samples is usually considered a major obstacle for three-dimensional (3D) structure determination of macromolecular complexes. Heterogeneity may occur at the level of composition or conformational variability of complexes and affects most 3D structure determination methods that rely on signal averaging. Here, an approach is described that allows sorting structural states based on a 3D statistical approach, the 3D sampling and classification (3D-SC) of 3D structures derived from single particles imaged by cryo electron microscopy (cryo-EM). The method is based on jackknifing & bootstrapping of 3D sub-ensembles and 3D multivariate statistical analysis followed by 3D classification. The robustness of the statistical sorting procedure is corroborated using model data from an RNA polymerase structure and experimental data from a ribosome complex. It allows resolving multiple states within heterogeneous complexes that thus become amendable for a structural analysis despite of their highly flexible nature. The method has important implications for high-resolution structural studies and allows describing structure ensembles to provide insights into the dynamics of multi-component macromolecular assemblies.

Diversions: Obstacles for Undergraduate Students when Applying for Internship Positions Online  [PDF]
Clarisse Halpern, Bruno Halpern
Open Journal of Business and Management (OJBM) , 2018, DOI: 10.4236/ojbm.2018.61011
Abstract:
The objective of this research was to investigate how the decision of Brazilian university students to enroll (or not) in internships’ selection processes would be affected by the form and content of the ads published in social media. Thus, a qualitative research was carried out through a multiple-case study. Data were collected in semi-structured interviews via Skype, as well as direct observations of eight individuals. The category?Diversions presented the most relevant results shedding light as to how the interviewees’ focus was shifted while searching for internship positions during their interviews. The title refers to how distractions make students stray from their intended search for internship positions. Instead, social media exerts a sort of magnetism that is more powerful than recruiting posts and ads, attracting their attention away from internship openings search, making them secondary. In conclusion, diversions were found to become obstacles for undergraduate students when applying for internship positions online.
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