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Search Results: 1 - 10 of 119354 matches for " Bruno O. Onyemegbulem "
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A Mathematical Modelling of the Effect of Treatment in the Control of Malaria in a Population with Infected Immigrants  [PDF]
Olaniyi S. Maliki, Ngwu Romanus, Bruno O. Onyemegbulem
Applied Mathematics (AM) , 2018, DOI: 10.4236/am.2018.911081
In this work, we developed a compartmental bio-mathematical model to study the effect of treatment in the control of malaria in a population with infected immigrants. In particular, the vector-host population model consists of eleven variables, for which graphical profiles were provided to depict their individual variations with time. This was possible with the help of MathCAD software which implements the Runge-Kutta numerical algorithm to solve numerically the eleven differential equations representing the vector-host malaria population model. We computed the basic reproduction ratio R0 following the next generation matrix. This procedure converts a system of ordinary differential equations of a model of infectious disease dynamics to an operator that translates from one generation of infectious individuals to the next. We obtained R0 = \"\", i.e., the square root of the product of the basic reproduction ratios for the mosquito and human populations respectively. R0m explains the number of humans that one mosquito can infect through contact during the life time it survives as infectious. R0h on the other hand describes the number of mosquitoes that are infected through contacts with the infectious human during infectious period. Sensitivity analysis was performed for the parameters of the model to help us know which parameters in particular have high impact on the disease transmission, in other words on the basic reproduction ratio R0.
Antibacterial Activity of Psidium guajava Leaf Extract against Selected Pathogenic Bacteria  [PDF]
Anayochukwu Chibuike Ngene, John C. Aguiyi, Chinedu Joshua Chibuike, Virginia O. Ifeanyi, Kelechi M. Ukaegbu-Obi, Esther Garos Kim, Uchechukwu C. Ohaeri, Bruno O. Onyemegbulem
Advances in Microbiology (AiM) , 2019, DOI: 10.4236/aim.2019.912066
Abstract: This study has been embarked upon due to increased resistance of bacteria to many already synthesized drugs and the high price of the orthodox medicines in the market, the antimicrobial effect of Psidium guajava leaf extracts against selected drug-resistant bacteria will help to reduce the overdependence on orthodox or synthetic drugs which greater population of the society cannot afford due to economic/financial restriction. Ethanolic and aqueous extracts of Psidium guajava were assayed for antibacterial activity using the agar dilution method in the determination of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The bioactive components of the extracts were determined using standard techniques and the inhibitory activities of the extracts were compared to gentamicin, ciprofloxacin, erythromycin, azithromycin, ofloxacin, and nitrofurantoin. The MIC of the extract on the test organisms ranges from 10 mg/ml - 40 mg/ml. The sensitivity test showed that the organisms were susceptible to Psidium guajava leave extract except Pseudomonas aeruginosa. The phytochemical analysis of the extracts revealed the presence of bioactive compounds such as Tannin, Saponin, Balsam, Flavonoids, Alkaloids, Cardiac glycosides, Carbohydrate, Resins, Terpenes, and Sterols. It has been shown that the leaves of Psidium guajava have antibacterial effects and hence can be used to treat the ailments caused by those organisms at a particular dosage and concentration. However, more research work on its toxicity level, synergistic or antagonistic interaction with other plants or drugs is needed to consolidate its usage.
A weak constraint qualification for conic programs and a problem on duality gap
Bruno F. Louren?o
Mathematics , 2015,
Abstract: We discuss a weak constraint qualification for conic linear programs and its applications for a few classes of cones. This constraint qualification is used to give a solution to a problem proposed by Shapiro and Z\v{a}linescu and show that if a closed convex cone is such that all its non-trivial faces are polyhedral and all the non-trivial exposed faces of its dual are polyhedral, then the duality gap is zero as long as the primal and dual problems are feasible. Moreover, the common optimal value must be attained at least at one of the sides. We also show an example of a cone that meets the requirements our theorem but is such that previously known results cannot be used to prove its good duality properties.
Public Relations between Occupation and Profession – Attempts at Regulating Public Relations
Bo?o Skoko,Bruno Jeli?
Medijske Studije , 2012,
Abstract: This paper is concerned with the regulation and the professionalization of occupations in public relations. It analyzes the role of professional, national associations in the professionalization process, providing an overview of these organizations in various countries around the world. The authors identify countries with no regulation (for instance, Italy), countries with some legal regulations (for instance, Brazil) and countries that have adopted self-regulation models (for instance, USA and South Africa). The authors point out the advantages and drawbacks of each regulation model and their impact on the development and professionalization of the occupation. Namely, in countries in which public relations are defined by law, public relations experts have guaranteed positions in society; however, they enjoy a negative public perception. In self-regulatory models, a significant number of experts are not covered by membership in organizations. Consequently, their behavior is not governed by any set of established professional obligations. Furthermore, countries with no clear professional regulation have enabled mass engagement in public relations; however, there are no criteria for professional advancement and affirmation. The issue of regulation in transition countries has shown itself to be a relatively unarticulated concept that can be expected to acquire greater definition with further professionalization of the occupation, a key role that must be played by professional associations.
Avalia o comportamental e farmacológica da rela o entre ansiedade e panico em modelos animais
Bruno de Oliveira Galv?o
Psicologia Clínica , 2008, DOI: 10.1590/s0103-56652008000100020
Relaxed complete partitions: an error-correcting Bachet's problem
Jorge Bruno,Edwin O'Shea
Mathematics , 2010,
Abstract: Motivated by an error-correcting generalization of Bachet's weights problem, we define and classify relaxed complete partitions. We show that these partitions enjoy a succinct description in terms of lattice points in polyhedra, with adjustments in the error being commensurate with translations in the defining hyperplanes. Our main result is that the enumeration of the minimal such partitions (those with fewest possible parts) is achieved via Brion's formula. This generalizes work of Park on classifying complete partitions and that of R{\o}dseth on enumerating minimal complete partitions.
Spatially dispersionless, unconditionally stable FC-AD solvers for variable-coefficient PDEs
O. P. Bruno,A. Prieto
Mathematics , 2012,
Abstract: We present fast, spatially dispersionless and unconditionally stable high-order solvers for Partial Differential Equations (PDEs) with variable coefficients in general smooth domains. Our solvers, which are based on (i) A certain "Fourier continuation" (FC) method for the resolution of the Gibbs phenomenon, together with (ii) A new, preconditioned, FC-based solver for two-point boundary value problems (BVP) for variable-coefficient Ordinary Differential Equations, and (iii) An Alternating Direction strategy, generalize significantly a class of FC-based solvers introduced recently for constant-coefficient PDEs. The present algorithms, which are applicable, with high-order accuracy, to variable-coefficient elliptic, parabolic and hyperbolic PDEs in general domains with smooth boundaries, are unconditionally stable, do not suffer from spatial numerical dispersion, and they run at FFT speeds. The accuracy, efficiency and overall capabilities of our methods are demonstrated by means of applications to challenging problems of diffusion and wave propagation in heterogeneous media.
De Novo Cavernous Malformation after Radiosurgery  [PDF]
Catarina Viegas, Bruno Santiago, Joana Boléo Tomé, Manuel Cunhae Sá
Open Journal of Modern Neurosurgery (OJMN) , 2013, DOI: 10.4236/ojmn.2013.31001

Background: The general use of radiation therapy and radiosurgery as first-line or adjuvant treatment of central nervous system (CNS) lesions has been associated with several harmful effects. Case Description: We report the case of a 16-year-old male patient, submitted at the age of seven to surgical removal of a world heath organization (WHO) grade II diffuse astrocytoma and referred for adjuvant radiosurgery after three further surgeries due to local recurrences. Seven years after radiosurgical treatment, he presented with symptoms of intracranial hypertension. Magnetic resonance imaging (MRI) at the time showed a cavernous malformation in the tumor bed, histologically confirmed, without tumoral recurrence. Conclusion: This case report emphasizes the relation between radiosurgery and the appearance of the novo cavernous malformations, only described previously in one adult patient.

Towards a Taxonomy of Firms Engaged in International R&D Networks: an Evaluation of the Spanish Participation in Eureka
Brand?o Fischer,Bruno; Molero Zayas,José;
Journal of technology management & innovation , 2012, DOI: 10.4067/S0718-27242012000300011
Abstract: innovation is increasingly becoming an internationalized process and a strategy that has recently been playing a central role in this scenario is that of r&d collaboration. to assess the outcomes of this strategy we develop an evaluation of eureka programme’s impact for the case of spanish companies participating in this initiative and that had projects finished in the period 2000-2005. a total of 77 firms were assessed through statistical association methods and cluster analysis. company size, role in the project, firm sector and r&d intensity are significantly associated with the projects’ impacts on spanish participants. a consistent taxonomy is offered in which three clusters are built: (1) risky innovators; (2) inventors; and (3) consistent innovators.
How Attractive are Innovation Systems for Knowledge Intensive Services’ FDI?: A Regional Perspective for Spain
Torrecillas,Celia; Brand?o Fischer,Bruno;
Journal of technology management & innovation , 2011, DOI: 10.4067/S0718-27242011000400004
Abstract: following an increasing body of literature that has been generated regarding the role played by knowledge intensive services in economic systems, our approach focuses on kis international orientation (fdi) according to the attractiveness we expect regional innovation systems might have in these flows. results suggest that technological variables participate rather marginally in the process of fdi attraction. as this situation unfolds more relevantly in the case of outward investment than inward, we can therefore expect that spanish investment abroad is more oriented towards asset and knowledge seeking than the inflow of investments in services and in kis in spanish regions.
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