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Search Results: 1 - 10 of 277092 matches for " Brunnella Alcantara Chagas de;Le?o "
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Terapia nutricional e sepse neonatal
Freitas, Brunnella Alcantara Chagas de;Leo, Renata Teixeira;Gomes, Andréia Patrícia;Siqueira-Batista, Rodrigo;
Revista Brasileira de Terapia Intensiva , 2011, DOI: 10.1590/S0103-507X2011000400015
Abstract: this article reviews the current understanding of enteral and parenteral nutrition therapy in preterm infants, with an emphasis on very low birth weight babies. the protective effects of nutrition therapy against neonatal sepsis and necrotizing enterocolitis are discussed. different methods of feeding preterm infants are evaluated. special attention is given to the problems of very low birth weight babies and the protective effects of nutrition to counteract complications, especially infection. the preferential use of breast milk for enteral nutrition, the management of protein and energy offers, the use of early and minimal enteral nutrition, the early introduction of parenteral nutrition (within the first 24 hours of life) and the use of immunonutrients that are appropriately supported by a sufficient number of studies can provide good adjuvant therapy guidelines to prevent neonatal sepsis and necrotizing enterocolitis. however, we conclude that additional multicenter, randomized controlled studies are necessary to clarify the protective role of nutrition in preterm infants. appropriate nutrition is not only effective in treating and preventing infective complications, but it also promotes neurodevelopment and prevents future harmful consequences.
Fatores associados à transfus o de concentrado de hemácias em prematuros de uma unidade de terapia intensiva Factors associated with packed red blood cell transfusions in premature infants in an intensive care unit
Brunnella Alcantara Chagas de Freitas,Sylvia do Carmo Castro Franceschini
Revista Brasileira de Terapia Intensiva , 2012, DOI: 10.1590/s0103-507x2012000300004
Abstract: OBJETIVO: Analisar os fatores associados à necessidade de transfus es de concentrados de hemácias em prematuros de uma unidade de terapia intensiva neonatal. MéTODOS: Estudo transversal de dados secundários de prematuros admitidos em unidade de terapia intensiva neonatal entre 2008 e 2010. Foram incluídos prematuros com baixo peso ao nascimento. A transfus o de concentrado de hemácias foi considerada a variável dependente. Empregaram-se os testes do qui-quadrado de Pearson ou exato de Fisher, e calcularam-se as medianas e os valores mínimos e máximos. Calcularam-se raz es de prevalências pela regress o de Poisson e o coeficiente de correla o de Pearson. Realizaram-se análises de regress o linear. Considerou-se significante p<0,05. RESULTADOS: Estudaram-se 254 prematuros e 39,4% receberam concentrado de hemácias. As transfus es foram 70% menos prevalentes entre os prematuros com idades gestacionais >32 semanas e 191% mais prevalentes naqueles acometidos por sepse neonatal tardia. O número de transfus es por paciente apresentou correla o negativa com a idade gestacional e positiva com a sepse neonatal tardia. A idade gestacional <32 semanas e a sepse neonatal tardia explicaram 45% das transfus es realizadas (p<0,0001). CONCLUS ES: Os prematuros com idade gestacional <32 semanas e os que evoluíram com sepse neonatal tardia apresentaram maior necessidade de transfus es de concentrados de hemácias. OBJECTIVE: This study analyzed the factors that are associated with the need for packed red blood cell transfusions in premature infants in a neonatal intensive care unit. METHODS: This study is a cross-sectional study of secondary data from premature infants who were admitted to a neonatal intensive care unit between 2008 and 2010. Premature infants with low birth weight were included. Packed red blood cell transfusion was the dependent variable. Pearson's Chi-square or Fisher's exact tests were used for data analysis, and the median, minimum, and maximum values were calculated. Prevalence ratios were calculated using the Poisson regression and Pearson correlation coefficient. Linear regression analyses were performed. P < 0.05 was considered to be significant. RESULTS: We examined 254 premature infants, and 39.4% of this sample received packed red blood cells. Transfusions were 70% less prevalent in premature infants who were born at >32 weeks of gestation, and 191% more prevalent in infants who exhibited late-onset neonatal sepsis. The number of transfusions per patient was negatively correlated with gestational age and positively correlated with late-onset n
Prevalência e fatores associados à displasia broncopulmonar em hospital de referência para microrregi o de Minas Gerais Prevalence and factors associated with bronchopulmonary dysplasia in a referral hospital in Minas Gerais, Brazil
Brunnella Alcantara Chagas de Freitas,Mirene Peloso,Guilherme Lobo da Silveira,Giana Zarbato Longo
Revista Brasileira de Terapia Intensiva , 2012, DOI: 10.1590/s0103-507x2012000200014
Abstract: OBJETIVO: Avaliar a prevalência e os fatores associados à displasia broncopulmonar em uma unidade de terapia intensiva neonatal. MéTODOS: Estudo transversal de dados secundários de prematuros nascidos com menos de 32 semanas de gesta o, admitidos em uma unidade de terapia intensiva neonatal. Utilizaram-se os testes qui-quadrado, Mann-Whitney e a regress o multivariada. Considerou-se p<0,05. RESULTADOS: Estudaram-se 88 prematuros. A displasia broncopulmonar ocorreu em 27,3% e se associou à idade gestacional inferior a 28 semanas (OR: 4,80; IC95%: 1,50-15,34; p=0,008) e à persistência do canal arterial (OR: 3,44; IC95%: 1,10-10,76; p=0,034). O grupo com displasia broncopulmonar utilizou maior tempo de ventila o mecanica, com mediana de 24,5 dias (p<0,0001). No momento da alta, as idades corrigida e cronológica foram maiores no grupo com displasia broncopulmonar (p<0,0001), com medianas respectivas de 38,4 semanas e 70,5 dias. CONCLUS ES: A prevalência de displasia broncopulmonar neste estudo foi elevada, associando-se à prematuridade extrema, à persistência do canal arterial, ao maior tempo de ventila o mecanica e ao prolongamento da interna o. Essa morbidade constitui problema de saúde pública em raz o do aumento da sobrevida dos prematuros de menores idades gestacionais. OBJECTIVE:The aim of the present study was to evaluate the prevalence and factors associated with bronchopulmonary dysplasia at a neonatal intensive care unit. METHODS: The study was a cross-sectional study that used secondary data from premature infants who were born with less than 32 weeks of gestational age and were admitted to a neonatal intensive care unit. Chi-square, Mann-Whitney and multivariate tests were used. Significance was set at p<0.05. RESULTS: A total of 88 premature infants were included in the study. Bronchopulmonary dysplasia occurred in 27.3% of the infants and was related to having a gestational age below 28 weeks (OR: 4.80; 95% CI: 1.50-15.34; p=0.008) and a patent ductus arteriosus (OR: 3.44; 95% CI: 1.10-10.76; p=0.034). The group with bronchopulmonary dysplasia used mechanical ventilation for a longer duration, with a median of 24.5 days (p<0.0001). At discharge, the corrected and chronological ages were higher in the group with bronchopulmonary dysplasia (p<0.0001), with respective medians of 38.4 weeks and 70.5 days. CONCLUSIONS: In this study, the prevalence of bronchopulmonary dysplasia was high; the high prevalence was related to extreme prematurity, patent ductus arteriosus, a longer period under mechanical ventilation and prolonged hospitalization. T
Características epidemiológicas e óbitos de prematuros atendidos em hospital de referência para gestante de alto risco Epidemiological characteristics and deaths of premature infants in a referral hospital for high-risk pregnancies
Brunnella Alcantara Chagas de Freitas,Luciana Ferreira da Rocha Sant'Ana,Giana Zarbato Longo,Rodrigo Siqueira-Batista
Revista Brasileira de Terapia Intensiva , 2012,
Abstract: OBJETIVO: Analisar o processo da assistência prestada aos prematuros atendidos em uma unidade de terapia intensiva neonatal e os fatores associados à sua mortalidade. MéTODOS: Estudo transversal de dados retrospectivos de prematuros de uma unidade de terapia intensiva no triênio 2008-2010. Descreveram-se características maternas e dos prematuros e realizou-se análise bivariada entre estas, o período de estudo e o desfecho "óbito" (hospitalar, neonatal e precoce) pelos testes do qui-quadrado de Pearson, exato de Fisher ou qui-quadrado de tendência linear. Aplicou-se a regress o logística bivariada e multivariável pelo método Stepwise Backward LR entre as variáveis com p<0,20 e o desfecho "óbito". Considerou-se significante p<0,05. RESULTADOS: Estudaram-se 293 prematuros. Os incrementos do acesso aos exames complementares (ultrassonografia transfontanelar e ecodoplercardiograma) e das taxas de aleitamento materno foram indicadores de melhoria da assistência. A mortalidade concentrada no período neonatal, especialmente no neonatal precoce, associou-se à prematuridade extrema, ao nascimento pequeno para idade gestacional e a Apgar <7 no 5o minuto de vida. A sepse tardia também associou-se à maior chance de óbitos neonatais e o corticoide antenatal mostrou-se protetor para os óbitos neonatais e precoces. CONCLUS ES : Apesar dos resultados comparáveis à realidade brasileira, o estudo enfatiza a necessária implementa o de estratégias para promo o do aleitamento materno e para redu o da mortalidade neonatal e de seu componente precoce. OBJECTIVE: To analyze the process of care provided to premature infants in a neonatal intensive care unit and the factors associated with their mortality. METHODS: Cross-sectional retrospective study of premature infants in an intensive care unit between 2008 and 2010. The characteristics of the mothers and premature infants were described, and a bivariate analysis was performed on the following characteristics: the study period and the "death" outcome (hospital, neonatal and early) using Pearson's chi-square test, Fisher's exact test or a chi-square test for linear trends. Bivariate and multivariable logistic regression analyses were performed using a stepwise backward logistic regression method between the variables with p<0.20 and the "death" outcome. A p value <0.05 was considered to be significant. RESULTS: In total, 293 preterm infants were studied. Increased access to complementary tests (transfontanellar ultrasound and Doppler echocardiogram) and breastfeeding rates were indicators of improving care. Mortality was conc
Sepse tardia em pré-termos de uma unidade de terapia intensiva neonatal: análise de três anos
Freitas, Brunnella Alcantara Chagas de;Peloso, Mirene;Manella, Lilyane Damasceno;Franceschini, Sylvia do Carmo Castro;Longo, Giana Zarbato;Gomes, Andréia Patrícia;Siqueira-Batista, Rodrigo;
Revista Brasileira de Terapia Intensiva , 2012, DOI: 10.1590/S0103-507X2012000100012
Abstract: objective: to evaluate the prevalence factors and etiologies associated with late neonatal sepsis in preterm neonates in a neonatal intensive care unit. methods: this was a cross-sectional study of secondary data pertaining to preterm neonates admitted to the neonatal intensive care unit between 2008 and 2010 and was gathered from medical charts. the outcome variable, late neonatal sepsis, was characterized using the brazilian national health surveillance agency criteria. pearson's chi-squared test, fisher's exact test and the linear trend chi-squared test were used to assess the qualitative variables for linear trends. the statistical significance level was set at p < 0.05. bivariate and multivariate analyses of the independent and dependent variables were conducted to obtain a measure of the effect and prevalence ratios, considering a p-value of less than 0.20 to indicate statistical significance. results: this study included 267 preterm neonates. of the participants, 28.5% were characterized as having late-onset sepsis. positive blood cultures were recorded for 17.1% of the neonates. death occurred in 8.2% of the total cases, and of these deaths, 68.2% occurred within the sepsis group. three deaths were associated with positive blood cultures, all of which grew gram-negative bacteria. the bivariate analysis demonstrated that as the gestational age and birth weight decreased, the prevalence of late-onset sepsis trended upward. ten or more days on mechanical ventilation was associated with late-onset neonatal sepsis in 80.8% of cases. peripherally inserted central catheters left in place for 11 or more days were associated with late-onset neonatal sepsis in 76.2% of cases. the multivariate analysis demonstrated that a peripherally inserted catheter left in place for less than 11 days was associated with late-onset neonatal sepsis. gram-negative bacteria, including klebsiella pneumoniae and escherichia coli, were the most frequent causative agents. conclusions: late
Infec??o por Clostridium tetani no recém-nascido: revis?o sobre o tétano neonatorum
Gomes, Andréia Patrícia;Freitas, Brunnella Alcantara Chagas de;Rodrigues, Denise Cristina;Silveira, Guilherme Lobo da;Tavares, Walter;Siqueira-Batista, Rodrigo;
Revista Brasileira de Terapia Intensiva , 2011, DOI: 10.1590/S0103-507X2011000400014
Abstract: although tetanus is a preventable disease by vaccination, it continues to claim lives around the world. whereas cases of accidental origin reflect insufficient population immunization, tetanus neonatorum reveals a double-nature fault-poor vaccination coverage of adults coupled with difficulties accessing appropriate prenatal care; this situation is aggravated by the extreme severity of tetanus in this age group in which the mortality rate can reach up to 80%. the early detection of tetanus in neonates is essential for immediately initiating the proper therapy. therefore, although reaching an early diagnosis of tetanus is important, the most relevant aspect is related to the appropriate management and prophylaxis of this disease. consequently, the aim of this article is to review neonatorum tetanus with an emphasis on its therapy and prevention.
Surface Modification of Commercial Activated Carbon (CAG) for the Adsorption of Benzene and Toluene  [PDF]
Anna Sylmara da Costa Lopes, Samira Maria Leo de Carvalho, Davi do Socorro Barros Brasil, Rosivaldo de Alcantara Mendes, Marcelo Oliveira Lima
American Journal of Analytical Chemistry (AJAC) , 2015, DOI: 10.4236/ajac.2015.66051
Abstract: In this work, we determined the surface characteristics of natural (CA-1) and HNO3 treated (CA-2) CAG. Equilibrium, kinetics and breakthrough for adsorption of benzene and toluene by CA-1 and CA-2 were studied. Concentrations of benzene and toluene (mg/L) were determined by gas chromatography with headspace extraction. The data of adsorption kinetic and equilibrium were best fitted by pseudo-second order model and Langmuir isotherm, respectively. The best results of benzene and toluene adsorption from fixed bed were obtained at volumetric flow rate (Q1 = 70 mL/min) using adsorbent CA-2. The study of inferential statistics revealed that CA-1 and CA-2 adsorbents are statistically different at a 5% significance level.
Time series analysis of water surface temperature and heat flux components in the Itumbiara Reservoir (GO), Brazil
Alcantara, Enner Herenio de;Stech, José Luiz;Lorenzzetti, Jo?o Ant?nio;Novo, Evlyn Márcia Leo de Moraes;
Acta Limnologica Brasiliensia , 2011, DOI: 10.1590/S2179-975X2012005000002
Abstract: aim: water temperature plays an important role in ecological functioning and in controlling the biogeochemical processes of the aquatic system. conventional water quality monitoring is expensive and time consuming. it is particularly challenging for large water bodies. conversely, remote sensing can be considered a powerful tool to assess important properties of aquatic systems because it provides synoptic and frequent data acquisition over large areas. the objective of this study was to analyze time series of surface water temperature and heat flux to advance the understanding of temporal variations in a hydroelectric reservoir. method: modis water-surface temperature (wst) level 2, 1 km nominal resolution data (mod11l2, version 5) were used. all available clear-sky modis/terra images from 2003 to 2008 were used, resulting in a total of 786 daytime and 473 nighttime images. time series of surface water temperature was obtained computing the monthly mean in a 3×3 window of three reservoir selected sites: 1) near the dam, 2) at the centre of the reservoir and 3) in the confluence of the rivers. in-situ meteorological data from 2003 to 2008 were used to calculate surface energy budget time series. cross-wavelet, coherence and phase analysis were carried out to compute the correlation between daytime and nighttime surface water temperatures and the computed heat fluxes. results: the monthly mean of the day-time wst shows lager variability than the night-time wst. all time series (daytime and nighttime) have a cyclical pattern, passing for a minimum (june - july) and a maximum (december and january). fourier and the wavelet analysis were applied to analyze this cyclical pattern. the daytime time series, presents peaks in 4.5, 6 12 and 36 months and the nighttime wst shows the highest spectral density at 12, 6, 3 and 2 months. the multiple regression analysis shows that for daytime wst, the heat flux terms explain 89% of the annual variation (rms = 0.89 °c, p < 0.0013).
Time series analysis of water surface temperature and heat flux components in the Itumbiara Reservoir (GO), Brazil Análise da série temporal da temperatura da superfície da água e dos componentes do balan o de calor no Reservatório de Itumbiara (GO), Brasil
Enner Herenio de Alcantara,José Luiz Stech,Jo?o Ant?nio Lorenzzetti,Evlyn Márcia Leo de Moraes Novo
Acta Limnologica Brasiliensia , 2011,
Abstract: AIM: Water temperature plays an important role in ecological functioning and in controlling the biogeochemical processes of the aquatic system. Conventional water quality monitoring is expensive and time consuming. It is particularly challenging for large water bodies. Conversely, remote sensing can be considered a powerful tool to assess important properties of aquatic systems because it provides synoptic and frequent data acquisition over large areas. The objective of this study was to analyze time series of surface water temperature and heat flux to advance the understanding of temporal variations in a hydroelectric reservoir. METHOD: MODIS water-surface temperature (WST) level 2, 1 km nominal resolution data (MOD11L2, version 5) were used. All available clear-sky MODIS/Terra images from 2003 to 2008 were used, resulting in a total of 786 daytime and 473 nighttime images. Time series of surface water temperature was obtained computing the monthly mean in a 3×3 window of three reservoir selected sites: 1) near the dam, 2) at the centre of the reservoir and 3) in the confluence of the rivers. In-situ meteorological data from 2003 to 2008 were used to calculate surface energy budget time series. Cross-wavelet, coherence and phase analysis were carried out to compute the correlation between daytime and nighttime surface water temperatures and the computed heat fluxes. RESULTS: The monthly mean of the day-time WST shows lager variability than the night-time WST. All time series (daytime and nighttime) have a cyclical pattern, passing for a minimum (June - July) and a maximum (December and January). Fourier and the Wavelet Analysis were applied to analyze this cyclical pattern. The daytime time series, presents peaks in 4.5, 6 12 and 36 months and the nighttime WST shows the highest spectral density at 12, 6, 3 and 2 months. The multiple regression analysis shows that for daytime WST, the heat flux terms explain 89% of the annual variation (RMS = 0.89 °C, p < 0.0013). For nighttime, the heat flux terms explain 94% (RMS = 0.53 °C, p < 0.0002). CONCLUSION: The daytime WST and shortwave radiation presents a good agreement for periods of 6 (with shortwave retarded) and 12 months (with shortwave advanced); For nighttime WST and longwave the good agreement is present for 1, 3, 6 and 12 months, all with longwave advanced in relation to WST. OBJETIVO: A temperatura da água possui uma importante fun o ecológica e no controle de processos biogeoquímicos em um corpo d'água. O monitoramento convencional da qualidade da água geralmente é dispendioso e que consome muito
Uso de contracep??o por adolescentes de escolas públicas na Bahia
Almeida,Maria da Concei??o Chagas de; Aquino,Estela Maria Leo de; Gaffikin,Lynne; Magnani,Robert J;
Revista de Saúde Pública , 2003, DOI: 10.1590/S0034-89102003000500004
Abstract: objective: there has been a growing interest in patterns of contraceptive use among adolescents, due, in particular, to the social relevance attached to pregnancy in this age group. therefore, the objective of the study was to investigate factors associated with the use of contraceptive methods among female and male adolescent students. method: a cross-sectional study was conducted, by means of self-applied questionnaires, among 4,774 students ranging from 11 to 19 years of age. prevalence with respect to the use of contraceptive methods during the first experience of sexual intercourse as well as the most recent one was calculated both separately, that is, for each of these events, and in conjunction as a measure of consistent use. logistic regression was carried out for simultaneous analysis of factors associated with the use of contraceptive methods and in order to calculate adjusted measures. results: among the 1,664 students who reported being sexually active, the factors positively associated with the consistent use of contraceptive methods among male students included a) postponing their first experience of sexual intercourse and interaction with a stable partner, b) the family as a potential supplier of contraceptive methods, and c) access to health services. on the other hand, among female students factors positively associated with the consistent use of contraceptive methods included a) recent sexual initiation, and b) having a father as their source of information regarding sexuality, contraception and std/aids prevention. pregnancy was reported by 6.4% of the boys and 18.1% of the girls, its absence was associated with the consistent use of contraceptives by them (the girls) (odds ratio=3.83; 2.06-7.15). conclusions: the results confirm the complexity of determining contraceptive behavior among adolescents and therefore reinforce the need to include multi-dimensional aspects of this theme in order to ensure the efficacy of sex education programs.
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