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Wikis: Promoting Collaborative Literacy through Affordable Technology in Content-Area Classrooms  [PDF]
Brianna Carney-Strahler
Creative Education (CE) , 2011, DOI: 10.4236/ce.2011.22011
Abstract: Educators may realize the impact technology has on students, but may be ill equipped to integrate high-tech devices into the classroom in an affordable way. Educators can capitalize on students’ experience with technology by incorporating wikis, a collaborative webpage, into classroom instruction. Studies indicate that wiki technology can greatly enhance student collaboration and build content-area literacy skills. There are several research-based applications for implementing wiki technology into content-area classrooms. However, educators must consider the effect of wikis on curricula before integrating wikis into the classroom.
The Utility of MMPI-2 Scores with a Correctional Population & Convicted Sex Offenders  [PDF]
Brianna Leigh Grover
Psychology (PSYCH) , 2011, DOI: 10.4236/psych.2011.26098
Abstract: The MMPI-2 is a widely used objective personality measure across all settings. It is especially useful in correctional settings due to its objectivity with standardized administration and scoring This helps aid many factors including volume, legal accountability, the nature of the clientele, and the need for security. Since assessments provide very useful information about prisoners for correctional staff, these factors make the MMPI-2 a very valuable test to use in prison. Studies have found no significant differences between African Americans and Caucasians, however have found subtle differences between MMPI-2 scores of males and female offenders. One specific area the MMPI-2 has been used for in prison is with sex offenders. Previous studies have aimed to use the MMPI-2 to identify high and low risk sex offenders, as well as differentiate between general sex offenders and internet sex offenders. Not only has it been used to identify certain sex offenders, it has been used in examining the predictors of completion of sex offender treatment programs.
Exercise Protects against Diet-Induced Insulin Resistance through Downregulation of Protein Kinase Cβ in Mice
Xiaoquan Rao, Jixin Zhong, Xiaohua Xu, Brianna Jordan, Santosh Maurya, Zachary Braunstein, Tse-Yao Wang, Wei Huang, Sudha Aggarwal, Muthu Periasamy, Sanjay Rajagopalan, Kamal Mehta, Qinghua Sun
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0081364
Abstract: Physical exercise is an important and effective therapy for diabetes. However, its underlying mechanism is not fully understood. Protein kinase Cβ (PKCβ) has been suggested to be involved in the pathogenesis of obesity and insulin resistance, but the role of PKCβ in exercise-induced improvements in insulin resistance is completely unknown. In this study, we evaluated the involvement of PKCβ in exercise-attenuated insulin resistance in high-fat diet (HFD)-fed mice. PKCβ-/- and wild-type mice were fed a HFD with or without exercise training. PKC protein expression, body and tissue weight change, glucose and insulin tolerance, metabolic rate, mitochondria size and number, adipose inflammation, and AKT activation were determined to evaluate insulin sensitivity and metabolic changes after intervention. PKCβ expression decreased in both skeletal muscle and liver tissue after exercise. Exercise and PKCβ deficiency can alleviate HFD-induced insulin resistance, as evidenced by improved insulin tolerance. In addition, fat accumulation and mitochondrial dysfunction induced by HFD were also ameliorated by both exercise and PKCβ deficiency. On the other hand, exercise had little effect on PKCβ-/- mice. Further, our data indicated improved activation of AKT, the downstream signal molecule of insulin, in skeletal muscle and liver of exercised mice, whereas PKCβ deficiency blunted the difference between sedentary and exercised mice. These results suggest that downregulation of PKCβ contributes to exercise-induced improvement of insulin resistance in HFD-fed mice.
Categorical Lagrangian Grassmannians and Brauer-Picard groups of pointed fusion categories
Dmitri Nikshych,Brianna Riepel
Mathematics , 2013,
Abstract: We analyze the action of the Brauer-Picard group of a pointed fusion category on the set of Lagrangian subcategories of its center. Using this action we compute the Brauer-Picard groups of pointed fusion categories associated to several classical finite groups. As an application, we construct new examples of weakly group-theoretical fusion categories.
Sphk1 Expression and Survival Outcomes in Squamous Cell Carcinoma of the Oral Cavity  [PDF]
Brianna N. Harris, Rizwan Masood, Uttam K. Sinha
Journal of Cancer Therapy (JCT) , 2013, DOI: 10.4236/jct.2013.43086

Sphingosine kinase 1 (SphK1) is an important mediator of apoptosis and the proliferation of cancer cells. It is upregulated in cells showing increasing radioresistance. Here we present the correlation between SphK1 expression and survival outcomes in patients with carcinoma of the oral cavity. A retrospective chart review was performed between January 2009 and August 2010 at the University of Southern California. Patients diagnosed with an advanced-stage primary tumor restricted to the oral cavity and a minimum follow-up of two years were included. Patients who did not receive post-operative radiation therapy were excluded. Eighteen patients met the inclusion criteria with 10 (55.6%) patients demonstrating high expression of SphK1 and 8 (44.4%) patients demonstrating a low-to-moderate expression of SphK1. Tumor recurrence occurred in 9 patients (50.0%): 5 patients (27.8%) in the SphK1high cohort at a mean time to progression of 2.5 mo and 4 patients (22.2%) in the SphK1low cohort at a mean time to progression of 11.0 mo (p = 0.023). Death occurred in 8 patients (66.7%) in the SphK1high cohort and 3 patients (16.7%) in the SphK1low cohort (p = 0.036). Higher expression of SphK1 correlates with greater radioresistance and poorer survival outcomes in patients with HNSCC of the oral cavity.

Localization phase diagram of two-dimensional quantum percolation
Brianna S. Dillon,Hisao Nakanishi
Physics , 2013, DOI: 10.1140/epjb/e2014-50397-4
Abstract: We examine quantum percolation on a square lattice with random dilution up to $q=38%$ and energy $0.001 \le E \le 1.6$ (measured in units of the hopping matrix element), using numerical calculations of the transmission coefficient at a much larger scale than previously. Our results confirm the previous finding that the two dimensional quantum percolation model exhibits localization-delocalization transitions, where the localized region splits into an exponentially localized region and a power-law localization region. We determine a fuller phase diagram confirming all three regions for energies as low as $E=0.1$, and the delocalized and exponentially localized regions for energies down to $E=0.001$. We also examine the scaling behavior of the residual transmission coefficient in the delocalized region, the power law exponent in the power-law localized region, and the localization length in the exponentially localized region. Our results suggest that the residual transmission at the delocalized to power-law localized phase boundary may be discontinuous, and that the localization length is likely not to diverge with a power-law at the exponentially localized to power-law localized phase boundary. However, further work is needed to definitively assess the characters of the two phase transitions as well as the nature of the intermediate power-law regime.
Further Properties of Reproducing Graphs  [PDF]
Jonathan Jordan, Richard Southwell
Applied Mathematics (AM) , 2010, DOI: 10.4236/am.2010.15045
Abstract: Many real world networks grow because their elements get replicated. Previously Southwell and Cannings introduced a class of models within which networks change because the vertices within them reproduce. This happens deterministically so each vertex simultaneously produces an offspring every update. These offspring could represent individuals, companies, proteins or websites. The connections given to these offspring depend upon their parent’s connectivity much as a child is likely to interact with their parent’s friends or a new website may copy the links of pre-existing one. In this paper we further investigate one particular model, ‘model 3’, where offspring connect to their parent and parent’s neighbours. This model has some particularly interesting features, including a degree distribution with an interesting fractal-like form, and was introduced independently under the name Iterated Local Transitivity by Bonato et al. In particular we show connections between this degree distribution and the theory of integer partitions and show that this can be used to explain some of the features of the degree distribution; we give exact formulae for the number of complete subgraphs and the global clustering coefficient and we show how to calculate the minimal cycle basis.
A Comparative Analysis of MMPI and Rorschach Findings Assessing Combat-Related PTSD in Vietnam Veterans—Analysis of MMPI and Rorschach Findings Assessing PTSD  [PDF]
Ioanna Katsounari, Jordan Jacobowitz
Psychology (PSYCH) , 2011, DOI: 10.4236/psych.2011.24053
Abstract: There has been a proliferation of assessment research on Post-traumatic Stress Disorder (PTSD) over the past twenty years. In spite of recent advances in the PTSD assessment research, there continues to be a controversy as to whether the MMPI or Rorschach is more useful in determining the presence of PTSD. The present comparative analysis of the research literature will carefully evaluate controlled empirical studies, which utilized psychometric measures such as the MMPI/2 and Rorschach to identify PTSD in Vietnam Veterans. This analysis is guided by the paucity of comparative data for standardized objective and projective instruments to assess combat-related PTSD. The analysis indicated that the MMPI as an assessment instrument focuses on symptom recognition of PTSD while the Rorschach seems to be more likely to identify chronic adaptations to trauma. The significance of pre-combat factors, such as preexisting personality, and their impact on the way individuals make meaning and express traumatic experiences needs to be further addressed in future research. The need for reliable and valid measures to assess combat-related PTSD is urgent as an increasing number of soldiers return from war zones.
Maximizing Sampling Efficiency  [PDF]
Harmon S. Jordan
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.411209
Abstract: Background and Goals: Although health care quality improvement has traditionally involved extensive work with paper records, the adoption of health information technology has increased the use of electronic record and administrative systems. Despite these advances, quality improvement practitioners now and for the foreseeable future need guidance in defining populations of individuals for study and in selecting and analyzing sample data from such populations. Statistical data analysis in health care research often involves using samples to make inferences about populations. The investigator needs to consider the goals of the study, whether sampling is to be used, and the type of population being studied. While there are numerous sampling strategies designed to conserve resources and yield accurate results, one of these techniques—use of the finite population correction (FPC)—has received relatively little attention in health care sampling contexts. It is important for health care quality practitioners to be aware of sampling options that may increase accuracy and conserve resources. This article describes common sampling situations in which the issue of the finite population correction decision often arises. Methods: This article describes 3 relevant sampling situations that influence the design and analysis phases of a study and offers guidance for choosing the most effective and efficient design. Situation 1: The study or activity involves taking a sample from a large finite target population for which enumerative inferences are needed. Situation 2: The population is finite and the study is enumerative. A complete enumerative count of “defects” in the process is needed so that remediation can occur. Here, statistical inference is unnecessary. Situation 3: The target population is viewed as infinite; such populations are “conceptual populations” [1] or “processes”. Results: The article shows how savings in resources can be achieved by choosing the correct analytic framework at the conceptualization phase of study design. Choosing the right sampling approach can produce accurate results at lower costs. Several examples are presented and the implications for health services research are discussed. Conclusion: By clearly specifying the objectives of a
A Review of Enteric-coated Mycophenolate Sodium for Renal Transplant Immunosuppression
Nathan Newbold,Brianna Riley,Karen Hardinger
Clinical Medicine : Therapeutics , 2009,
Abstract: Mycophenolic acid inhibits an enzyme, inosine monophosphate dehydrogenase (IMPDH), blocking purine synthesis of lymphocytes and therefore functioning as an effective immunosuppressive agent in transplantation. Currently, there are two available forms of mycophenolic acid (MPA) available; mycophenolate mofetil (MMF) and enteric-coated, delayed-release mycophenolate sodium (EC-MPS). Both products are approved for prophylaxis of organ rejection in renal transplant recipients. The use of MPA may be associated with adverse gastrointestinal effects which can lead to a reduction of the dose or discontinuation of therapy. Enteric-coated MPS was developed to reduce the upper gastrointestinal side effects due to its delayed release in the small intestines. Similar systemic MPA exposure is provided by oral administration of MMF 1000 mg daily and EC-MPS 720 mg, which contain near equimolar MPA content. Clinical trials in renal transplant recipients have demonstrated that EC-MPS is therapeutically equivalent to MMF when used at the time of transplantation and when used for conversion for gastrointestinal complications. The available literature regarding the incidence and severity of gastrointestinal adverse effects and the impact on quality of life remains controversial. Prospective, randomized trials of the available MPA formulations are warranted to further explore the gastrointestinal adverse effect profiles.
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