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Search Results: 1 - 10 of 198265 matches for " Brian D Reiss "
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Anticipatory evolution and DNA shuffling
Jamie M Bacher, Brian D Reiss, Andrew D Ellington
Genome Biology , 2002, DOI: 10.1186/gb-2002-3-8-reviews1021
Abstract: Proteins are machines created by evolution, but it is unclear just how finely evolution has guided their sequence, structure, and function. It is undoubtedly true that individual mutations in a protein affect both its structure and its function and that such mutations can be fixed during evolutionary history, but it is also true that there are other elements of protein sequence that have been acted upon by evolution. For example, the genetic code appears to be laid out so that mutations and errors in translation are minimally damaging to protein structure and function [1]. Could the probability that a beneficial mutation is found and fixed in the population also have been manipulated during the course of evolution, so that the proteins we see today are more capable of change than the proteins that may have been cobbled together following the 'invention' of translation? Have proteins, in fact, evolved to evolve? There is already some evidence that bacteria are equipped to evolve phenotypes that are more capable of further adaptation (reviewed in [2,3,4]). For example, mutator [5] and hyper-recombinogenic [6] strains arise as a result of selection experiments. The development of DNA shuffling (reviewed in [7,8]) and the appearance of several recent papers using this technique [9,10,11] provide us with a surprising new opportunity to ask and answer these fundamental questions at the level of individual genes, and perhaps even genomes.DNA shuffling, a method for in vitro recombination, was developed as a technique to generate mutant genes that would encode proteins with improved or unique functionality [12,13]. It consists of a three-step process that begins with the enzymatic digestion of genes, yielding smaller fragments of DNA. The small fragments are then allowed to randomly hybridize and are filled in to create longer fragments. Ultimately, any full-length, recombined genes that are recreated are amplified via the polymerase chain reaction. If a series of alleles o
Blended Change Management: Concept and Empirical Investigation of Blending Patterns  [PDF]
Michael REISS
iBusiness (IB) , 2009, DOI: 10.4236/ib.2009.12008
Abstract: In coping with the challenges of revolutionary or evolutionary change processes, change managers do not rely on single tools but on toolboxes containing several domains of tools. The impact of toolboxes on change performance depends both on the complementary inter-domain mix and the intra-domain blending of tools. The patterns of blending are investigated both conceptually and empirically with respect to scope, diversity and coupling of tools. Survey results indicate that blending practices are predominantly determined by rational tool evaluation and by task context.
A Real-Time Semiautonomous Audio Panning System for Music Mixing
Enrique Perez_Gonzalez,Joshua D. Reiss
EURASIP Journal on Advances in Signal Processing , 2010, DOI: 10.1155/2010/436895
Abstract: A real-time semiautonomous stereo panning system for music mixing has been implemented. The system uses spectral decomposition, constraint rules, and cross-adaptive algorithms to perform real-time placement of sources in a stereo mix. A subjective evaluation test was devised to evaluate its quality against human panning. It was shown that the automatic panning technique performed better than a nonexpert and showed no significant statistical difference to the performance of a professional mixing engineer.
Automatic Noise Gate Settings for Drum Recordings Containing Bleed from Secondary Sources
Michael Terrell,Joshua D. Reiss,Mark Sandler
EURASIP Journal on Advances in Signal Processing , 2010, DOI: 10.1155/2010/465417
Renormalized mean-field analysis of antiferromagnetism and d-wave superconductivity in the two-dimensional Hubbard model
J. Reiss,D. Rohe,W. Metzner
Physics , 2006, DOI: 10.1103/PhysRevB.75.075110
Abstract: We analyze the competition between antiferromagnetism and superconductivity in the two-dimensional Hubbard model by combining a functional renormalization group flow with a mean-field theory for spontaneous symmetry breaking. Effective interactions are computed by integrating out states above a scale Lambda_{MF} in one-loop approximation, which captures in particular the generation of an attraction in the d-wave Cooper channel from fluctuations in the particle-hole channel. These effective interactions are then used as an input for a mean-field treatment of the remaining low-energy states, with antiferromagnetism, singlet superconductivity and triplet pi-pairing as the possible order parameters. Antiferromagnetism and superconductivity suppress each other, leaving only a small region in parameter space where both orders can coexist with a sizable order parameter for each. Triplet pi-pairing appears generically in the coexistence region, but its feedback on the other order parameters is very small.
Magnetic and superconducting correlations in the two-dimensional Hubbard model
W. Metzner,J. Reiss,D. Rohe
Physics , 2005, DOI: 10.1002/pssb.200562445
Abstract: The interplay and competition of magnetic and superconducting correlations in the weakly interacting two-dimensional Hubbard Model is investigated by means of the functional renormalization group. At zero temperature the flow of interactions in one-loop approximation evolves into a strong coupling regime at low energy scales, signalling the possible onset of spontaneous symmetry breaking. This is further analyzed by a mean-field treatment of the strong renormalized interactions which takes into account magnetic and superconducting order simultaneously. The effect of strong correlations on single-particle properties in the normal phase is studied by calculating the flow of the self-energy.
Expectations for Presentation of Engineering and Scientific Mobile Platform Information within a Virtual Globe Geographic Information Systems  [PDF]
Brian Guise, Michael D. Proctor
Journal of Geographic Information System (JGIS) , 2011, DOI: 10.4236/jgis.2011.32008
Abstract: Layered information systems like Google Earth have revolutionized public access to and visualization of geographic information through virtual globes. Separately, geo-specific technical information has been advanced in mobile platforms, both handheld and embedded devices, for the engineering and scientific communities. However, engineering and scientific information has had limited penetration into virtual globe Geographic Information Systems (GIS). This article explores unmet expectations which may be at the root of the issue. These expectations include design of the architecture within the originating mobile platform as well as expression of the level of accuracy and precision necessary for validity of the simulation displayed through the virtual globe GIS. The article below discusses architecture and validity research that advances real-time generation of simulated electro-magnetic coverage maps as composed layers within a mobile platform. Further, the research also enables real-time visualization of the simulated coverage maps by a global team through a virtual globe. Finally, for communication assurance purposes, the level of validity of the generated simulated coverage maps are analyzed from the perspective of an analog celestial body exploration mission by a mobile rover and its supporting organization analysis needs.
Short Report: Identifying Sources of Subsurface Flow—A Theoretical Framework Assessing Hydrological Implications of Lithological Discontinuities  [PDF]
Martin Reiss, Peter Chifflard
Open Journal of Modern Hydrology (OJMH) , 2014, DOI: 10.4236/ojmh.2014.43008
An integrative theoretical concept—combining scientific approaches from soil science and slope hydrology—is given as a framework to study the influence of depth functions of geochemical concentrations for trace elements, dissolved organic carbon and stable isotopes in the soil pore water of stratified soils on the chemical composition of the hillslope runoff. Combining investigations at the point and hillslope scale opens the opportunity to identify sources of subsurface runoff components using geochemical depth functions as proxies.
The Mount Stromlo Abell Cluster Supernova Search
David J. Reiss,Lisa M. Germany,Brian P. Schmidt,C. W. Stubbs
Physics , 1997, DOI: 10.1086/300191
Abstract: We have initiated a three-year project to find supernovae (SNe) in a well-defined sample of high-density southern Abell clusters with redshifts $z\leq0.08$. These observations will provide a volume-limited sample of SNe Ia to more than a magnitude below their peak brightness, and will enable us to: (1) measure the luminosity function of SNe, (2) further explore the correlation of light curve shape with the absolute luminosity of SNe Ia to better understand SNe Ia as distance indicators, (3) measure SN rates, (4) measure the bulk motion of the Local Group using SNe Ia, and (5) directly compare SN Ia distances to brightest cluster galaxy distances. We use the MaCHO wide-field 2-color imager on the 1.3m telescope at Mount Stromlo to routinely monitor $\sim 12$ clusters per week. We describe our technique for target selection and scheduling search observations, and for finding and identifying SN candidates. We also describe the results from the first year of our program, including the detection of 19 SNe, several RR-Lyrae variables, and hundreds of asteroids.
SN1997cy/GRB970514 - A New Piece in the GRB Puzzle?
Lisa M. Germany,David J. Reiss,Elaine M. Sadler,Brian P. Schmidt,C. W. Stubbs
Physics , 1999, DOI: 10.1086/308639
Abstract: We present observations of SN1997cy, a supernova discovered as part of the Mount Stromlo Abell Cluster SN Search, which does not easily fit into the traditional classification scheme for supernovae. This object's extraordinary optical properties and coincidence with GRB970514, a short duration gamma ray burst, suggest a second case, after SN1998bw/GRB980425, for a SN-GRB association. SN1997cy is among the most luminous SNe yet discovered and has a peculiar spectrum. We present evidence that SN1997cy ejected approximately 2 solar masses of 56Ni, supported by its late-time light curve, and FeII/[FeIII] lines in its spectrum, although it is possible that both these observations can be explained via circumstellar interaction. While SN1998bw and SN1997cy appear to be very different objects with respect to both their gamma ray and optical properties, SN1997cy and the optical transient associated with GRB970508 have roughly similar late-time optical behavior. This similarity may indicate that the late-time optical output of these two intrinsically bright transient events have a common physical process. Although the connection between GRB970514 and SN1997cy is suggestive, it is not conclusive. However, if this association is real, followup of short duration GRBs detected with BATSE or HETE2 should reveal objects similar to SN1997cy.
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