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Search Results: 1 - 10 of 2492 matches for " Branka Jana? "
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Diabetic osteopathy
Ili? Jana,Kova?ev Branka
Medicinski Pregled , 2005, DOI: 10.2298/mpns0504147i
Abstract: Introduction. The aim of this study was to point out some dilemmas about the existence and pathogenesis of primary diabetic osteopathy as a separate entity, based on currently available studies. Expert disagreements are present not only about the occurrence of generalized osteopathy with diabetic disease, but also about direct relationship between metabolic diabetes control and bone metabolism and influence of disease duration and sex on bone changes. Pathogenesis of diabetic osteopathy Decreased bone formation is the basic mechanism leading to decreased bone mass. Biochemical markers showed no clear connection with bone density measurement. Insulin and insulin-like growth factor (IGF) affect bone metabolism. Osteopathy in patients with diabetic disease-type 1 Some clinical studies have shown that patients with diabetic disease-type 1 have a mild decrease in bone mass, while others have not presented such results. Osteopathy in patients with diabetic disease-type2 In patients with diabetic disease-type 2 the risk for osteopathy is even less defined. Patients treated with oral hypoglycemics present with higher decrease of bone mass has than patients treated with insulin therapy. This could partly be explained by anabolic effects of insulin on bones. Bone fractures in patients with diabetic disease Literature data are contradictory concerning the occurrence of bone fractures in diabetic patients. A survey of bone fracture occurrence in diabetic patients was performed in "Veljko Vlahovi Medical Center" in Vrbas and it included a group of 100 patients with diabetic disease. The results show that 12 patients had some fractures: mostly females in postmenopause, aged and with secondary insulin-dependent diabetes and most frequently arm fractures. Considering contradictory literature data, further longitudinal studies are necessary. .
Efficiency of Printing Technologies of Graphically Protected Materials
Branka Moric Kolaric,Ivan Budimir,Jana Ziljak Vujic
Acta Graphica : Journal for Printing Science and Graphic Communications , 2012,
Abstract: This paper attempts to make a hierarchical assessment of graphic protection in orderto enhance its use. It was established that the most common types of approvedprotection are also the best known ones and that their implementation enhancesprotection efficiency on products which are often counterfeit. Printing offices, publishersand design authors will protect their high demand products which are subjectto counterfeiting by optimizing printing technology, implementation expensesand efficiency of the protection system. By means of a system of questioning anddata processing, we created a scale of values of protective graphic technologies,inks and graphic materials. A survey showed that a large number of examineesbelieves in the possibility of counterfeit ballot papers and a hypothesis was testedwhich proved that 95% of citizens think that protective graphic techniques shouldbe used to prevent the counterfeiting of ballot papers. We therefore recommendthe individualization of ballot papers and the implementation of invisible graphics.It has been proved that citizens would have more confidence in the democraticelections if guaranteed the protection of ballot papers, which would finally result inthe increased number of turnouts.
Effects of hyperthyroidism on bone mass in women of reproductive age
Ili? Jana,Kova?ev Branka,Todorovi?-?ilas Ljiljana R.
Medicinski Pregled , 2004, DOI: 10.2298/mpns0404111i
Abstract: Introduction Hyperthyroidism is one of the most frequent endocrinopathies in women of reproductive age. Consequently, increased risk of osteoporosis may be expected. Material and methods The research has included a group of 30 hyperthyroid women and a control group of 30 healthy women of reproductive age. Age and some clinical characteristics were analyzed, as well as some anthropometric parameters. Bone mass parameters were determined by measuring bone mineral density using ultrasound devices (SAHARA-Hologic). Results Bone mass parameters in hyperthyroid women are significantly lower than in controls (BUA: 63.25±12.17; 69.73±10.02 dB/MHz respectively; SOS:1523.90± 24.47; 1540.19±26.59 m/s respec. QUI/STIFF 79.78±13.95; 89.09±13.99 % respec.) Duration of hyperthyroidism affects bone density and reduces it. Discussion Obtained results were expected, having in mind that hyper- thyroidism is a condition characterized by increased bone catabolic rate. Also, negative correlation between the duration of hyperthyroidism and bone mass parameters (BUA, SOS) was expected, because it is logical that consolidation of bone mass in adult life cannot be maintained in circumstances in which metabolic rate is increased. During hyperthyroidism, bone loss is expected. In order to confirm this, future studies of bone markers are necessary. Conclusion Based on results obtained in the study, the following conclusions were made: hyperthyroidism is accompanied by decreased values of bone mass parameters; this effect depends on duration of hyperthyroidism. We confirmed that hyperthyroidism may be the cause of decrease in bone mass, particularly if it lasts more than a year. To prevent osteoporosis in women of reproductive age with hyperthyroidism and involution osteoporosis later in life, early diagnosis and effective therapy of hyperthyroidism is imperative.
Effects of alendronate on the markers of bone metabolic activity in postmenopausal women with osteoporosis
Ili? Jana,Kova?ev Branka,Babi? Ljiljana J.,?uri? Nikola
Medicinski Pregled , 2005, DOI: 10.2298/mpns0508393i
Abstract: Introduction Bisphosphonates are synthetic compounds used in treatment of osteoporosis and inhibition of bone resorption. Material and methods The research included a group of 30 postmenopausal women with osteoporosis, treated with alendronate (70 mg per week -Fosamax tablets in combination with calcium and active vitamin D - Alpha D3 0.25mcg). The control group included 20 women with osteoporosis treated with hormone substitution therapy (HST), calcitonin and deca duraboline. Bone metabolic activity, was evaluated using osteocalcin for bone formation and cross-laps for bone resorption. Blood samples were taken before therapy and 6-8 weeks after. Results The serum levels of osteocalcin and cross-laps during application of alendronate were statistically significantly lower comparing to those in pre-therapy. The serum levels of osteocalcin and cross-laps during the therapy applied in the control group were statistically insignificantly lower than values in pretherapy. Osteocalcin has a tendency of decreasing in both groups, and it was slightly more evident in alendronate group. Cross-laps demontrated the same tendency of decreasing in both groups, and it was more evident in alendronate group. Discussion Our results have shown the efficacy of alendronate in preventing bone loss, which was highly statistically significant. They have also shown its suppressive effect on bone formation and resorption, but the effects were statistically less significant. Conclusion Alendronate significantly reduces the level of bone resorption in postmenopausal women with osteoporosis. Its effects on bone formation are less expressed. Alendronate's effects on bone metabolism become evident not later than 6-8 weeks after therapy application. Parameters of bone metabolic activity are very useful diagnostic means in evaluation of alendronate effect on bone metabolic activity and in the prognosis of bone mass loss.
Ghrelin effects on the activities of digestive enzymes and growth of Lymantria dispar L.
Peri?-Mataruga Vesna,JanaBranka,Vlahovi? Milena,Mrdakovi? Marija
Archives of Biological Sciences , 2012, DOI: 10.2298/abs1202497m
Abstract: Ghrelin, along with several other hormones, has significant effects on appetite and growth in humans and animals. The aim of our study was to examine changes in relative growth rates, α- and β-glucosidase activities and endocrine cell size in the midgut of 4th instar caterpillars of the pest insect Lymantria dispar L. after ghrelin treatment. Four subpicomolar injections of ghrelin (0.3 pmol) or physiological saline were applied every 24 h to two separate groups of fifteen caterpillars. Repeated administration of ghrelin in subpicomolar doses elevated the relative growth rate, induced α- and β-glucosidase activities and increased the size of endocrine cells. The results are the first data about ghrelin effects on relative growth rate, digestive enzyme activities and midgut endocrine cells in insects. This information supports the use of this relatively simple model system in future studies of mechanisms underlying digestion in complex organisms.
Effect of glutamate antagonists on nitric oxide production in rat brain following intrahippocampal injection
Radenovi? Lidija,Selakovi? Vesna,JanaBranka,Todorovi? Dajana
Archives of Biological Sciences , 2007, DOI: 10.2298/abs0701029r
Abstract: Stimulation of glutamate receptors induces neuronal nitric oxide (NO) release, which in turn modulates glutamate transmission. The involvement of ionotropic glutamate NMDA and AMPA/kainate receptors in induction of NO production in the rat brain was examined after injection of kainate, a non-NMDA receptor agonist; kainate plus 6-cyano- 7-nitroquinoxaline-2,3-dione (CNQX), a selective AMPA/kainate receptor antagonist; or kainate plus 2-amino-5-phosphonopentanoic acid (APV), a selective NMDA receptor antagonist. Competitive glutamate receptor antagonists were injected with kainate unilaterally into the CA3 region of the rat hippocampus. The accumulation of nitrite, the stable metabolite of NO, was measured by the Griess reaction at different times (5 min, 15 min, 2 h, 48 h, and 7 days) in hippocampus, forebrain cortex, striatum, and cerebellum homogenates. The used glutamate antagonists APV and CNQX both provided sufficient neuroprotection in the sense of reducing nitrite concentrations, but with different mechanisms and time dynamics. Our findings suggest that NMDA and AMPA/kainate receptors are differentially involved in nitric oxide production.
Extremely Low Frequency Magnetic Field (50 Hz, 0.5 mT) Reduces Oxidative Stress in the Brain of Gerbils Submitted to Global Cerebral Ischemia
Sne?ana Rau? Balind, Vesna Selakovi?, Lidija Radenovi?, Zlatko Proli?, Branka Jana
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0088921
Abstract: Magnetic field as ecological factor has influence on all living beings. The aim of this study was to determine if extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) affects oxidative stress in the brain of gerbils submitted to 10-min global cerebral ischemia. After occlusion of both carotid arteries, 3-month-old gerbils were continuously exposed to ELF-MF for 7 days. Nitric oxide and superoxide anion production, superoxide dismutase activity and index of lipid peroxidation were examined in the forebrain cortex, striatum and hippocampus on the 7th (immediate effect of ELF-MF) and 14th day after reperfusion (delayed effect of ELF-MF). Ischemia per se increased oxidative stress in the brain on the 7th and 14th day after reperfusion. ELF-MF also increased oxidative stress, but to a greater extent than ischemia, only immediately after cessation of exposure. Ischemic gerbils exposed to ELF-MF had increased oxidative stress parameters on the 7th day after reperfusion, but to a lesser extent than ischemic or ELF-MF-exposed animals. On the 14th day after reperfusion, oxidative stress parameters in the brain of these gerbils were mostly at the control levels. Applied ELF-MF decreases oxidative stress induced by global cerebral ischemia and thereby reduces possible negative consequences which free radical species could have in the brain. The results presented here indicate a beneficial effect of ELF-MF (50 Hz, 0.5 mT) in the model of global cerebral ischemia.
Achieving the Objectives of Arts and Cultural Education in Slovenian Pre-Service Teacher Training  [PDF]
Olga Denac, Branka ?agran
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.38207
Abstract: The paper presents the results of research involving students from across Slovenia, exploring opinions on whether the objectives of arts and cultural education in their higher education have been met so far and their attitude towards education and the arts. The results of the research show that the general aims of arts and cultural education were more frequently incorporated in the study process than the aims relating to developing an attitude towards cultural heritage. Students from various study programs agree in particular on the need for team planning of the learning process, and on the importance of art education in the development of the individual’s creative potential. However, they agree less on measures aimed at improving the quality of art education and viewpoints relating to the content of future preschool and school teacher higher education. The results relating to the research aims also display statistically significant differences between study programs. Arts and cultural education in the education system was given higher importance by students of social sciences, preschool education and class teaching than by students of natural sciences.
Evolu??o do modo de regula??o escolar e reestrutura??o da fun??o de diretor de escola
Cattonar, Branka;
Educa??o em Revista , 2006, DOI: 10.1590/S0102-46982006000200010
Abstract: these last ten years, the educational systems of the provinces in canada knew several important changes in their mode of regulation which have effects on the conditions and the content of the work of the school actors. our article intends studying their effects on the work of the principals of schools: how do they feel the recent school evolutions? how do they live, do they conceive and do they exercise their work today? we shall try to answer these questions on base of the results of a survey by questionnaire realized in 2005 with 2144 principals of elementary and secondary schools in the whole of canada. the survey shows that most of the principals have a qualified vision of the impacts of the school evolutions, that their work implies on the exercise of a multitude of responsibilities and that it appears to bring them a professional satisfaction under numerous aspects.
Spatial structure changes of cities in the post socialist period
To?i? Branka
Glasnik Srpskog Geografskog Dru?tva , 2006, DOI: 10.2298/gsgd0601165t
Abstract: The paper gives the overview of the policy of urban planning in CEE and Southeast Europe during the socialist period. That policy was based on centralistic system which caused specific type of internal structure of the cities. Besides that, the paper compares the changes in the urban planning that took place during the 1990s as the results of global and integrational processes, market rules and privatization, decentralization deindustrialization, commercialization, social segregation etc. These changes are already obvious in urban areas. At the end of the last century unstable policy and economic crisis in Serbia slowed down these processes both the changes in the functional-spatial structure of the cities and especially the changes related to the institutional policy in urban planning.
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