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Search Results: 1 - 10 of 23 matches for " Boukaré;Lamien "
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Antiacetylcholinesterase and antioxidant activity of essential oils from six medicinal plants from Burkina Faso
Kiendrebeogo, Martin;Coulibaly, Ahmed Y.;Nebie, Roger C. H.;Zeba, Boukaré;Lamien, Charles E.;Lamien-Meda, Aline;Nacoulma, Odile G.;
Revista Brasileira de Farmacognosia , 2011, DOI: 10.1590/S0102-695X2011005000008
Abstract: in this investigation, we evaluated essential oils from six medicinal plants from burkina faso for their antiacetylcholinesterase and antioxidant abilities. the chemotype of most active were also determined. the best antiacetylcholinesterase activities were recorded for the essential oils of eucalyptus camaldulensis (ic50 18.98 μ g/ml) and ocimum canum (ic50 36.16 μ g/ml). their chemotype have been related to the 1,8-cineole one. both essential oils demonstrated a linear mixed non competitive inhibition. the essential oil of ocimum basilicum which belong to the linalool-eugenol chemotype exhibited the best radical scavenging activity (ic50 3.82 μ g/ml) and reducing power (531.75 mg aae/g). in comparison with gallic and ascorbic acids, o. basilicum essential oil evidenced interesting antioxidant activities. the antiacetylcholinesterase and antioxidant activities of essential oils were discussed in regard with their chemical composition.
Antioxidant and Antibacterial Activities of Combretum nioroense Aubrév. Ex Keay (Combretaceae)
T.H. Coulidiati,H. Millogo-Kone,A. Lamien-Meda,C.E. Lamien
Pakistan Journal of Biological Sciences , 2009,
Abstract: In this study, the antioxidant and antibacterial activities of acetone extract, ethyl acetate, n-butanol and n-hexane fractions of acetone extract from leaves of Combretum nioroense Aubrév. ex Keay were investigated. The total phenolics and total flavonoids contents in the fractions and acetone extract were determined by spectrophotometric methods using Folin-Ciocalteu and AlCl3, respectively. Two methods were adopted to assess the antioxidant activities: the Ferric Reducing Antioxidant Power (FRAP) and the radical scavenging activity of 2, 2’-azinobis (3-ethylbenzothiozoline-6-sulfonate) radical cation (ABTS). The Minimum Inhibitory Concentrations (MICs) of the extract and fractions against pathogenic bacteria (4) and serotyped bacteria (4) from American Type Culture Collection (ATCC) were also determined using the agar-well diffusion method. The results showed that the butanol fraction, with the highest phenolic content, exhibited the best antioxidant and antibacterial activities as compared to the ethyl acetate fraction which contains more flavonoids.
Polyphenol Contents and Antioxidant Activities of Five Indigofera Species (Fabaceae) from Burkina Faso
S. Bakasso,A. Lamien-Meda,C.E. Lamien,M. Kiendrebeogo
Pakistan Journal of Biological Sciences , 2008,
Abstract: Aqueous acetone extracts prepared from five Indigofera species of Burkina Faso, namely Indigofera colutea (Burm.) Murril., I. macrocalyx Guilld et Perr., I. nigritana Hook f., I. pulchra willd. and I. tinctoria L., were investigated for their phytochemical composition and their antioxidant activities. Standard methods and TLC were used to screen the phytochemical composition. The total phenolic and flavonoid content of extracts were assessed by Folin-Ciocalteu and AlCl3 methods, respectively. These extracts were also evaluated for their antioxidant potentials using ferric reducing antioxidant power (FRAP), 2,2-diphenyl-l-picrylhydrazyl (DPPH) and 2,2`-azinobis(3-ethylbenzothiazoline-6-sulphonate) (ABTS) assays. Flavonoids, saponins, quinones, sterols/triterpenes and tannins were present in all these species except for I. pulchra where quinones were not found. Gallic acid, caffeic acid, rutin and myricetin in I. colutea; gallic acid, quercitrin, myricetin in I. tinctoria; galangin and myricetin in I. macrocalyx were identified by thin layer chromatography. Among these, I. colutea, I. tinctoria, I. nigritana and I. macrocalyx, which had the highest phenolic content, were also found to possess the best antioxidant activities. The results indicated a good correlation between antioxidant activities and total phenolic content (p<0.05 for FRAP/DPPH and DPPH/ABTS and p<0.01 for FRAP/ABTS). These plants represent promising sources of natural antioxidants and these findings give scientific bases to their ethnopharmacological uses.
In vitro Antioxidant, Xanthine Oxidase and Acetylcholinesterase Inhibitory Activities of Balanites aegyptiaca (L.) Del. (Balanitaceae)
N.T.R. Meda,A. Lamien-Meda,M. Kiendrebeogo,C.E. Lamien
Pakistan Journal of Biological Sciences , 2010,
Abstract: The present study aimed to test the validity of Balanites aegyptiaca remedies used for the treatment of rheumatisms and mental disorders by examining the antioxidant, xanthine oxidase and acetylcholinesterase inhibitory activities of galls and leaves extracts and fractions. The total phenolics and flavonoids were measured using Folin-Ciocalteu and AlCl3 reagents, respectively. Two methods i.e., FRAP and ABTS were used to estimate the total antioxidant capacity of the plant materials. The FRAP and ABTS antioxidant activities showed that among all extracts and fractions tested, the best antioxidant activities were found with the galls dichloromethane and the leaves ethyl acetate fractions. The antioxidant activities did correlated significantly with the total phenolic and flavonoid contents. The study also showed that B. aegyptiaca galls and leaves fractions exhibited a moderate xanthine oxidase inhibitory activity comparatively to the acetylcholinesterase which was weakly inhibited by the tested extracts and fractions.
In vitro Inhibition of Acetyl Cholinesterase, Lipoxygenase, Xanthine Oxidase and Antibacterial Activities of Five Indigofera (Fabaceae) Aqueous Acetone Extracts from Burkina Faso
S. Bakasso,A. Lamien-meda,C.E. Lamien,M. Kiendrebeogo
Current Research Journal of Biological Sciences , 2013,
Abstract: The aim of this study is to evaluate the inhibition of oxidative stress related enzymes of aqueous acetone extracts, as well as antibacterial activity from five Indigofera species well-known medicinal plant from Burkina. Also are investigated in this study the potential contribution of tannins and of flavonol in these activities Particularly, aqueous acetone extracts were investigated for their Lipoxygenase (LOX), Xanthine Oxidase (XO) and Acetylcholinesterase (AChE) inhibitions that are implied in inflammation, gout and Alzheimer’s etiology diseases. Interestingly, I. macrocalyx which had the highest flavonol content (of all) showed more inhibition against LOX and XO (51.16 and 77.33% respectively). Our study showed a significant correlation between XO inhibition and total flavonol content (R2 = 0.9052). AChE was low sensible to all extracts. In contrast, the extracts were rich in tannin compounds especially in I. tinctoria extract. And results of the in vitro antibacterial activities of these extracts against five bacteria showed that all bacteria were sensible to all extracts particularly S. typhimurium and B. cereus. Our results suggest that the five studied species prove to be good sources of inhibition of the three enzymes involved in oxidative stress and also to have some antibacterial properties. That is what probably explains their uses in folk medicine, singularly, in the treatment of gout, dysentery and anti-inflammatory diseases.
Effect of Drying Air Velocity on Drying Kinetics of Tomato Slices in a Forced-Convective Solar Tunnel Dryer  [PDF]
Mamouda Moussa Na Abou, Sa?dou Madougou, Makinta Boukar
Journal of Sustainable Bioenergy Systems (JSBS) , 2019, DOI: 10.4236/jsbs.2019.92005
Abstract: The objective of this work is to analyse the extent to which a change in the drying air velocity may affect the drying kinetics of tomato in a forced-convective solar tunnel dryer. 2 m?s?1 (V1) and 3 m?s?1 (V2) air speeds were applied in similar drying air temperature and humidity conditions. Main drying constants calculated included the drying rate, the drying time and the effective water diffusivity based on the derivative form of the Fick’s second law of diffusion. Henderson and Pabis Model and Page Model were used to describe the drying kinetics of tomato. We found that solar drying of tomato occurred in both constant and falling-rate phases. The Page Model appeared to give a better description of tomato drying in a forced-convective solar tunnel dryer. At t = 800 min, the drying rate was approximately 0.0023 kg of water/kg dry matter when drying air velocity was at 2 m/s. At the same moment, the drying rate was higher than 0.0032 kg of water/kg dry matter when the drying air velocity was 3 m/s. As per the effective water diffusivity, its values changed from 2.918E?09 m2?s?1 to 3.921E?09 m2s?1 when drying air velocity was at 2 and 3 m?s?1 respectively, which is equivalent to a 25% increase. The experimentations were conducted in Niamey, on the 1st and 5th of January 2019 for V2 and V1 respectively. For both two experiments, the starting time was 9:30 local time.
Local Communities Demand for Food Tree Species and the Potentialities of Their Landscapes in Two Ecological Zones of Burkina Faso  [PDF]
Daniabla Natacha Edwige Thiombiano, Niéyidouba Lamien, Ana M. Castro-Euler, Barbara Vinceti, Dolores Agundez, Issaka Joseph Boussim
Open Journal of Forestry (OJF) , 2013, DOI: 10.4236/ojf.2013.33014
Abstract:

We examined demand and supply of Food Tree Species (FTS) products in Burkina Faso. The hypotheses were: 1) demand for FTS products by local communities exceeds what can be sustainably extracted, and 2) local communities of the Sudanian zone have access to more diverse FTS products compared to Sahelian zone. Surveys were conducted in 300 households and 360 quadrats in landscapes surrounding 6 villages to determine the diversity, richness and availability of FTS. The results indicate that local communities tend to exploit FTS which are rare to find or absent in the landscape surrounding their village. While the range of FTS largely exploited tends to coincide across the two ecological zones, the diversity and density of the preferred FTS are discordant between the two zones. The results of the present study further support the need for conservation and restoration strategies to sustain the local communities demand for FTS products.

Major Enzymatic Factors Involved in Bacterial Penicillin Resistance in Burkina Faso
Boukare Zeba,Martin Kiendrebeogo,Aline Lamien,Jean-Denis Docquier
Pakistan Journal of Biological Sciences , 2007,
Abstract: Many clinical species of bacteria were isolated from biological samples such as urines, blood and wound in Saint Camille medical centre of Ouagadougou. Among the concerned species, the most important members were Escherichia coli and Klebsiella pneumoniae. These β-lactamases producing isolates were directly screened by PCR to identify the nature of the amplified genes responsible for penicillin destroying activity. Therefore specific TEM and SHV primers were used. The PCR products were sequenced. The sequencing results indicated that the parental forms blaTEM-1 and blaSHV-1 were the most common determinants of β-lactamase found, respectively in Escherichia species and Klebsiella pneumoniae. The bacterial susceptibility analysis by MICs measurement clearly correlated the presence of concerned β-lactamase determinants and their resistance patterns. This study is part of a set of investigations carried out by our laboratory to assess the β-lactamase incidence in the failure of β-lactam therapy. In particular, the purpose of this study was to determine the precise nature of β-lactamase supporting the low susceptibility of host bacteria towards penicillins.
Phenolic Content and Antioxidant Activity of Six Acanthaceae from Burkina Faso
Wamtinga Richard Sawadogo,Aline Meda,Charles Euloge Lamien,Martin Kiendrebeogo
Journal of Biological Sciences , 2006,
Abstract: In this study the total phenolic and flavonoid content as well as the antioxidant activity of six Acanthaceae namely Blepharis lineariifolia PERS, Dicliptera verticillata (FORRSK.) C. CHRISTENS, Dyschoriste perrottetii (NEES) O. KTZE, Hygrophila auriculata (SCHUMACH.) HEINE, Lepidagathis anobrya NEES, Nelsonia canescens (LAM) SPRENG were evaluated. The total phenolic and flavonoid of their aqueous acetone extract were assessed by Folin-ciocalteu and AlCl3 method, respectively, whereas the antioxidant activities were determined by the DPPH method. Lepidagathis anobrya, Hygrophila auriculata and Nelsonia canescens which had the highest phenolic content, were found to possess the best antioxidant activities. The results suggest that these plants are good sources of antioxidants and support their use in cardiovascular and antiinflammatory diseases.
Laxative Effect of Some Plants Extracts Used in Traditional Pharmacopoeia on the Intestine of Rabbit  [PDF]
Imar Djibrine Soudy, Arada Izzedine Abdelaziz, Djidda Alhadj, Ousmane Dahab Atteib, Boukar Abba Alifa, Djimalbaye Mandiguel, Ngomde Djasnabaye, Hassane Mahamat Hassane
Food and Nutrition Sciences (FNS) , 2016, DOI: 10.4236/fns.2016.712110
Abstract: Constipation is a condition in which a person or animal has difficulty in eliminating solid waste from the body and the faeces are hard and dry. It is mainly characterized by a difficulty in defecation. The aim of the study is to assess the laxative effect of some plants such as Adansonia digitata , Ziziphus mauritiana and Psidium guayava traditionally used in Chad to treat the problems of constipation. The Microdynamometer method (Biomecatronics) is used to carry out this study. The outcomes show that the extracts’ leaves of Psidium guayava and barks of Ziziphus mauritiana did not lead a significant contraction of duodenum of rabbit until a maximum concentration of 1000 μg, but the extracts’ leaves of Adansonia digitata had a significant effect (P < 0.05) on the intestinal motility of rabbit. This effect of the extract of Adansonia digitata varies with the increase of its concentration (dose dependent) with a maximum of 500 μg and the minimal effect is inferior to 10 μg. On the other hand, the extract of Adansonia digitata has a musculotrope effect because the results have shown that inhibitive molecules such as the atropine and the naloxone do not have to inhibit the action of Adansonia digitata on the intestinal motility of rabbit. Thus, the extract of this plant would reduce significantly the time of intestinal transit and it will be an important laxative drug candidate as described traditionally in Chad.
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