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Search Results: 1 - 10 of 6234 matches for " Bone cement "
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Osteoclastoma of Proximal Ulna―Atypical Location in a 13-Year-Old Child  [PDF]
Siddaram Patil, Ranjit Kumar Yalamanchili
Open Journal of Orthopedics (OJO) , 2014, DOI: 10.4236/ojo.2014.43009
Abstract: Giant cell tumour (GCT) or osteoclastoma is a very rare locally invasive bone tumour that occurs close to the joint. The ulnar metaphysis is an unusual site for an Osteoclastoma with occurrence rate of 0.45% to 3.2% as reported in literature [1]. Most of the patients seek traditional methods of treatment before orthopaedic consultation and present lately with extensive involvement of the tumour into soft tissues and articular surface, making the joint preservation difficult or impossible. For reconstruction, several options have been described, which include fibular autografts, allografts and cement augmentation. Inherent to all these procedures is the risk of delayed union of the graft and preserving functional mobility of the joint. We report a rare case of a proximal ulna GCT diagnosed in a 13-year-old girl. It was treated with intralesional curettage, and autologous maternal iliac crest bone grafting augmented with bone cement reconstruction.
Resternotomy Following Sternal Bone Cement Implantation: A Great Challenge for Cardiac Surgeons  [PDF]
Aliasghar Moeinipour, Alireza Sepehri Shamloo, Alireza Abdollahi Moghadam, Mohammad Sobhan Sheikh Andalibi, Ahmad Reza Zarifian, Hamid Hoseinikhah
Journal of Biosciences and Medicines (JBM) , 2015, DOI: 10.4236/jbm.2015.311010
Abstract: Background: Median sternotomy and resternotomy is the standard technique for coronary artery bypass grafting (CABG), valvular heart disease, and congenital heart disease. Despite ad-vances in many areas of cardiac surgical procedures, there is a lack of innovation in sternal closure techniques. Several studies have examined sternal closure techniques including wiring, interlocking, plate and screw, and bone cementation. However, none of them achieved widespread acceptability. On one hand, serious post-operative complications are associated with the use of wiring and plating techniques in high-risk patients. The aim of this study is showing challenges and difficulties with resternotomy in patient with a history of previous cardiac surgery and usage of biologic bone cements. Case Report: The case was a 56-year-old woman with a history of previous sternotomy for mitral and aortic valve replacement (mechanical sj. No. 29 and mechanical sj. No. 21, respectively) using biologic bone cement (Kryptonite TM, Doctors Research Group Inc.) for her osteopenic sternum. Four years after the mitral valve replacement (MVR), she was referred to emergency department with a thrombosis at the mitral valve. She under-went emergent cardiac surgery with a very difficult resternotomy under femoral cannulation support. Conclusion: Resternotomy in patients with previous sternotomy with Kryptonite bone cements or calcium phosphate cements (CPC) is safe and can be done similar to other cardiac reoperations. It seems that reoperation in this patients does not increase the risk of bleeding, morbidity, and mortality.
Modeling of Daptomycin Release from Medium-Dose Daptomycin-Xylitol-Loaded PMMA Bone Cements  [PDF]
Ali Salehi, Gladius Lewis, Ashley Cox Parker, Warren O. Haggard
Journal of Biomedical Science and Engineering (JBiSE) , 2014, DOI: 10.4236/jbise.2014.76037
Abstract: Antibiotic-loaded poly (methyl methacrylate) bone cements (ALPBCs) are widely used as an agent to decrease the occurrence of periprosthetic joint infection (PJI). Most often, the antibiotic used in an ALPBC is gentamicin, tobramycin, or vancomycin. In many recent clinical studies, it has been reported that the pathogens that commonly present in PIJ are becoming resistant to these antibiotics. As such, a new generation of antibiotics is emerging, among which is daptomycin. Literature reports with a clinically relevant medium-dose daptomycin-loaded cement show that the daptomycin release rate from cylindrical specimens is low. Incorporation of a poragen, such as dextrose, glycine, or particulate xylitol, into the cement powder has been shown to be an effective way to increase daptomycin release rate. There are, however, no studies on modeling of daptomycin release from specimens of either a daptomycin-loaded cement or a daptomycin-poragen-loaded cement. In the present work, we determine the profiles of daptomycin release from cylindrical medium-dose daptomycin-xylitol-loaded cement specimens, as a function of the particulate xylitol loading. We used these results and relationships that have been shown to model antibiotic release from ALPBC specimens to obtain the best-fit relationship for the present cements. Through this approach, we demonstrated that, regardless of the xylitol loading, the daptomycin release profile is a mixture of initial burst followed by a slow Fickian diffusion.
Material properties and in vitro biocompatibility of a newly developed bone cement
Mitzner, Elke;Pelt, Paco Albertus Hubert Maria;Mueller, Christian;Strohwig, Angela;Mueller, Wolf-Dieter;
Materials Research , 2009, DOI: 10.1590/S1516-14392009000400013
Abstract: in this study mechanical properties and biocompatibility (in vitro) of a new bone cement were investigated. a new platform technology named cool is a variable composite of dissolved, chemically modified pmma and different bioceramics. cool cures at body temperature via a classical cementation reaction. compressive strengths ranging from 3.6 ± 0.8 to 62.8 ± 1.3 mpa and bending strengths ranging from 9.9 ± 2.4 to 26.4 ± 3.0 mpa were achieved with different cool formulations. porosity varied between 31 and 43%. varying the components of each formulation mechanical properties and porosity could be adjusted. in vitro biocompatibility studies with primary human osteoblasts (phob) in direct contact with different cool formulations, did not reveal any signs of toxicity. in contrast to refobacin? r, cells incubated with cool showed similar density, viability and alp activity compared to control, if specimen were added immediately to the cell monolayer after preparation. in conclusion, cool has promising mechanical properties in combination with high biocompatibility in vitro and combines different advantages of both cpcs and pmma cements by avoiding some of the respective shortcomings.
Recent advances in the use of glass ionomers: bone substitutes
SALATA, Luiz Antonio;SVERZUT, Cássio Edvard;XAVIER, Samuel Porfírio;
Revista de Odontologia da Universidade de S?o Paulo , 1999, DOI: 10.1590/S0103-06631999000200016
Abstract: the purpose of this study is to update the reader upon the latest scientific trends concerning the use of glass ionomer cements (gics). these materials which have been found of large clinical application in dentistry worldwide, have recently been successfully tested as bone substitutes in minor surgical procedures. the new perspectives of the use of glass ionomer as an osteoconductive material is analysed in the light of its biological properties as a restorative material.
Recent advances in the use of glass ionomers: bone substitutes
SALATA Luiz Antonio,SVERZUT Cássio Edvard,XAVIER Samuel Porfírio
Revista de Odontologia da Universidade de S?o Paulo , 1999,
Abstract: The purpose of this study is to update the reader upon the latest scientific trends concerning the use of glass ionomer cements (GICs). These materials which have been found of large clinical application in dentistry worldwide, have recently been successfully tested as bone substitutes in minor surgical procedures. The new perspectives of the use of glass ionomer as an osteoconductive material is analysed in the light of its biological properties as a restorative material.
Percutaneous vertebroplasty in the management of vertebral lesions
Purkayastha S,Gupta A,Kapilamoorthy T,Kesavadas C
Neurology India , 2005,
Abstract: Background : Debilitating backache due to different types of vertebral lesions is a common cause of morbidity in all age groups. Percutaneous vertebroplasty (PV) gives substantial pain relief and stabilizes the weak vertebrae. Most of the information regarding PV comes from the Western literature. The effect of PV in our population should be studied. Aims : The primary objective is to assess the therapeutic benefit of PV in alleviating back pain and improving the functional status in patients with painful pathologic vertebrae. The secondary objectives are to study the technical aspects of the procedure and their relation to outcome and complications. Settings and Design : This is a retrospective hospital-based (tertiary teaching hospital) study. Materials and Methods : From January 2001 to December 2004, 46 patients underwent PV procedures. Sixty-five vertebroplasties were done in 13 males and 33 female patients. Twenty-four (36.92%) procedures were done for osteoporotic compression collapse, 26 (40.0%) for hemangioma, and 15 (23.07%) for different vertebral body tumors and metastasis. The Wilcoxon signed rank test was used to evaluate the statistical significance of differences between the preoperative and postoperative levels of pain, mobility and analgesic usage. Results: Most of the patients had pain relief within 48 h. Only minor side effects were encountered. No patient had any deficit related to the procedure. On follow up of 3-48 months, all patients had statistically significant improvement in clinical condition (P < 0.001). Conclusion : Percutaneous vertebroplasty is a safe and effective procedure in relieving debilitating backache and can be used to treat vertebral lesions in selected cases.
Incudostapedial Rebridging Ossiculoplasty with Bonecement after Temporal Bone Trauma
Mehmet Ali BABADEMEZ,Baran ACAR,Hayriye KARABULUT et al.
Duzce Universitesi Tip Fakültesi Dergisi , 2010,
Abstract: Though it is not very frequent, hearing loss can be experienced after head traumas. Surgicalintervention is occasionally required in persistant conductive hearing loss, and incudostapedialjoint injury often occurs during these interventions. In incudostapedial joint repair, ossicularprothesis, shaped bone and cartilage autogrefts are usually used. However; these methods havevarious disadvantages. In this case we report a case of incudostapedial joint repair with hydroxyapatite bone cement which is easily applicable, cheap and has favored audiological results in achild who experienced conductive hearing loss after temporal trauma.
Stiffness and strength of composite acrylic bone cements
I. Knets,V. Krilova,R. Cimdins,L. Berzina
Journal of Achievements in Materials and Manufacturing Engineering , 2007,
Abstract: Purpose: Different acrylic bone cements based upon PMMA-MMA system are applicable for implant fixation inbone tissue. The aim of present study is the optimisation of the structure of some new bone acrylic cements madeon the basis of PMMA-ethylmethacrylate-triethyleneglycoldimethacrylate and bone cements having additives (HAand radio pacifier), and the finding of the effect of these modifications on the flexural strength and stiffness.Design/methodology/approach: Different new bone cements on the basis of PMMA-EMA-TEGDMA system(ABC) were developed experimentally. The stiffness and strength of the samples of these modified cements weredetermined in the special three point bending equipment.Findings: A comparison of the flexural properties of new PMMA-EMA-TEGDMA cements and commercialavailable PMMA-MMA cement showed that commercial bone cement had larger values of ultimate strengthand modulus of elasticity, but the difference is not very important. As concerns the polymerisation peaktemperature, then there is a significant difference between commercial PMMA-MMA cement (~ 800C) andPMMA-EMA-TEGDMA modified cements (50 – 600C). The introduction of 10% and 18% of HA into solidphase does not influence essentially strength and modulus of elasticity of the PMMA-EMA-TEGDMA bonecements. The introduction of radio pacifier BaSO4 into bone cement leads to flexural strength diminishing.Low polymerisation peak temperature and appropriate mechanical properties of bone cements developed allowsregarding new 3-D structure acrylic bone cements as promising biomaterials.Research limitations/implications: It is supposed to carry out animal testing to learn more about reaction ofmodified implanted material on the biological environment.Practical implications: The new materials could be efficiently used as bone cements because they will notdamage surrounding biological tissue during curing.Originality/value: Paper is providing the new information about possibilities to realize the safe fixation of implants.
Influência de aditivos na injetabilidade de cimento ósseo de fosfato tricálcico
Alves, Hugo Leonardo Rocha;Santos, Luis Alberto dos;Bergmann, Carlos Pérez;
Matéria (Rio de Janeiro) , 2006, DOI: 10.1590/S1517-70762006000300022
Abstract: calcium phosphate cements are biomaterials made of a mixture of calcium phosphate powder with water or with aqueous solutions of inorganic or organic salts, forming a paste that reacts at room or body temperature and hardens as a result of precipitation reactions. calcium phosphate cements are commonly used in both dentistry and orthopedic bone filling surgeries, which require extremely invasive procedures. the innovation consists in formulate an injectable paste by incorporation of additives. in this work, three different additives (carboxymethylcellulose, agar polymer and calcium alginate) were incorporated in alpha-tricalcium phosphate (a-tcp), in concentrations of 0.4%; 0.8%; 1.6%; 3.2% and 6.4% wt%. results showed that it was possible to obtain injectable compositions of tricalcium phosphate cement. it was verified that the injectability, measured by a novel method, depends on the rheological behavior of the pastes and injection time. in this study, pastes with sufficient viscosity for good homogenization and injection were obtained. in this study, pastes with 1.6% carboxymethylcellulose, 1.6% agar and 0.8% sodium alginate present sufficient viscosity for good homogenization for cement injection.
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