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Search Results: 1 - 10 of 60290 matches for " Bi Yan Liang "
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Progress on Research for the Treatment of HIV/AIDS with Traditional Chinese Medicine in China  [PDF]
Jian Wang, Bi Yan Liang
World Journal of AIDS (WJA) , 2011, DOI: 10.4236/wja.2011.13016
Abstract: The mortality rate associated with HIV/AIDS has decreased dramatically after highly active antiretroviral therapy (HAART). However, issues such as viral reservoirs, drug resistance and side effects have led to a significant crisis in the management of HIV/AIDS. It has become evident that HAART does not offer a complete solution to the problem. Therefore, additional and alternative therapeutic strategies urgently need to be explored. Traditional Chinese medicine (TCM) is one of the mainstays of complementary and alternative medicine, and its use has aroused increasing attention. This paper reviews the recent progress in the use of TCM, from single herbs, herbal ingredients, compound Chinese herbal medicine, acupuncture and medical care, for the treatment of HIV/AIDS in China. We also review evaluation systems that assess the efficacy of TCM.
Is Helicobacter Pylori Infection Associated with Asthma Risk? A Meta-Analysis Based on 770 Cases and 785 Controls
Yan Wang, Yutian Bi, Liang Zhang, Changzheng Wang
International Journal of Medical Sciences , 2012,
Abstract: Objective: Helicobacter pylori (H. pylori) infection has been thought to play a critical role in disorders such as gastric and lung cancer. A number of studies have been devoted to the relationship between H. pylori infection and asthma risk, which have generated inconclusive results. In this study we aimed to derive a more precise estimation of the relationship. Methods: Meta-analyses evaluating the association of H. pylori infection and asthma risk were conducted and subgroup analyses on ethnicity and source of controls as well as CagA status were further conducted. Eligible studies were identified for the period up to Jul 2012. Results: A total of five case-control studies comprising 770 cases and 785 controls were lastly selected for analysis. The overall data failed to indicate a significant association of H. pylori infection and asthma risk (OR=1.01; 95%CI=0.82-1.24). Likewise, in the subgroup analysis regarding ethnicity, source of controls and CagA status, no associations could be observed. Conclusions: The pooled data failed to suggest a marked association between H. pylori infection and asthma risk. Future studies are needed to confirm this conclusion.
Up-regulation of p21 and TNF-α is mediated in lycorine-induced death of HL-60 cells
Jing Liu, Ji-liang Hu, Bi-Wei Shi, Yan He, Wei-Xin Hu
Cancer Cell International , 2010, DOI: 10.1186/1475-2867-10-25
Abstract: When HL-60 cells were treated with different concentration of lycorine, the expression of p21 and TNF-α was up-regulated in a concentration-dependent manner as shown by real-time quantitative reverse transcriptase-polymerase chain reaction and Western blotting. Lycorine also down-regulated p21-related gene expression, including Cdc2, Cyclin B, Cdk2 and Cyclin E, promoted Bid truncation, decreased IκB phosphorylation and blocked NF-κB nuclear import. Cytochrome c was released from mitochondria as observed with confocal laser microscopy.The TNF-α signal transduction pathway and p21-mediated cell-cycle inhibition were involved in the apoptosis of HL-60 cells induced by lycorine. These results contribute to the development of new lycorine-based anti-leukemia drugs.A tumor is a disease with two defining characteristics: a proliferation disorder and an apoptosis obstacle. The inhibition of proliferation and the induction of apoptosis are regulated by a network of signaling pathways and transcription factors, which may represent potential targets for rational tumor therapy [1,2]. Apoptotic events are regulated by the interplay of proapoptotic and antiapoptotic proteins. The apoptotic pathways include two major signaling pathways: the death receptor-induced pathway and the mitochondria-apoptosome-mediated pathway. Elements of the death receptor pathway include cell death ligands and their receptors, such as tumor necrosis factor (TNF) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor, and downstream molecules, such as caspase 8. The major components of the mitochondrial pathway include apoptotic stimuli, mitochondria, the apoptosome, and key effector caspases [1]. Crosstalk between these two apoptotic pathways is mediated through the truncation of the BH3-interacting death domain (Bid) protein. Inhibitors of apoptosis proteins include the X-linked inhibitor of apoptosis protein (XIAP), the cellular inhibitor of apoptosis protein (cIAP), survivin,
Clinical Significance and Role of Lymphatic Vessel Invasion as a Major Prognostic Implication in Non-Small Cell Lung Cancer: A Meta-Analysis
Jun Wang, Baocheng Wang, Weipeng Zhao, Yan Guo, Hong Chen, Huili Chu, Xiuju Liang, Jingwang Bi
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0052704
Abstract: Background Lymphatic vessel invasion (LVI) exerts an important process in the progression and local spread of cancer cells. However, LVI as a prognostic factor for survival in non-small cell lung cancer (NSCLC) remains controversial. Methodology/Principal Findings A meta-analysis of published studies from PubMed and EMBASE electronic databases was performed to quantity the effects of LVI on both relapse-free survival and overall survival for patients with NSCLC. Hazard ratios (HRs) with 95% confidence intervals (95% CIs) were used to assess the strength of these effects. This meta-analysis included 18,442 NSCLC patients from 53 eligible studies. LVI appeared in 32.1% (median; range, 2.8% to 70.9%) of tumor samples. In all, patients with LVI were 2.48 times more likely to relapse by univariate analysis (95% CI: 1.92–3.22) and 1.73 times by multivariate analysis (95% CI: 1.24–2.41) compared with those without LVI. For the analyses of LVI and overall survival, the pooled HR estimate was 1.97 (95% CI: 1.75–2.21) by univariate analysis and 1.59 (95% CI: 1.41–1.79) by multivariate analysis. Multivariate analysis showed a risk was 91% higher for recurrence (HR = 1.91, 95% CI: 1.14–2.91) and 70% higher for mortality (HR = 1.70, 95% CI: 1.38–2.10) in LVI-positive I stage patients compared with LVI-negative I stage patients. Subgroup analyses showed similar significant adjusted risks for recurrence and death in adenocarcinomas, and a significant adjusted risk for death in studies that utilized elastic staining with or without immunohistochemistry in defining LVI. Conclusions/Significance The present study indicates that LVI appears to be an independent poor prognosticator in surgically managed NSCLC. NSCLC patients with LVI would require a more aggressive treatment strategy after surgery. However, large, well-designed prospective studies with clinically relevant modeling and standard methodology to assess LVI are required to address some of these important issues.
R-plane Sapphire Substrate for Non-polar GaN Film
非极性GaN用r面蓝宝石衬底

YANG Xin-Bo,XU Jun,LI Hong-Jun,BI Qun-Yu,CHENG Yan,SU Liang-Bi,ZHOU Guo-Qing,
杨新波

无机材料学报 , 2009,
Abstract: R-plane sapphire used for epitaxial growth of non-polar GaN film was grown by the temperature gradient technique (TGT) method and chemical mechanical method was used to polish the r-plane sapphire substrate. The crystallization quality, optical property and surface roughness of as-obtained r-plane sapphire substrate were investigated. The average full width at half maximum (FWHM) of the substrate is 19.4arcsec and the dislocation density is 5.6×103cm-2. The transmission of the substrate is higher than 80% when the wavelength is longer than 300nm and the optical homogeneity is 6.6×10-5. The average surface roughness of the r-plane sapphire substrate is 0.49nm. The results indicate that as-obtained r-plane sapphire substrate meets the basic standard of GaN substrate.
Growth of | Al2O3 Crystal by Edge-Defined, Film-Fed Growth Technique
YANG Xin-Bo,LI Hong-Jun,BI Qun-Yu,CHENG Yan,SU Liang-Bi,TANG Qiang,XU Jun
无机材料学报 , 2009, DOI: 10.3724/sp.j.1077.2009.00255
Abstract: | Al2O3 crystal was grown by Edge-Defined, Film-Fed Growth Technique (EFG) in which graphite heating unit and shield acted as the carbon source and high purity Al2O3 was used as the raw material. Thermoluminescence (TL) and optically stimulated luminescence (OSL) properties of as-grown crystal after annealing in H2 were investigated. The crystal shows a single one-order kinetic glow peak at 460K and blue emission band at 415nm. OSL decay curve of | Al2O3 crystal shows exponential characteristic. The decay curve is made up of two components, i.e. the faster component and the slower component. The TL and OSL responses of | Al2O3 crystal show lineara2sublineara2saturation characteristics. The TL exhibits good linear dose response in the dose range from 5 0-6 to 0.2Gy and saturation is about 10Gy. The OSL exhibits good linear dose response in the dose range from 5 0-6 to 10Gy and saturation is about 30Gy.
R-plane Sapphire Substrate for Non-polar GaN Film
YANG Xin-Bo,XU Jun,LI Hong-Jun,BI Qun-Yu,CHENG Yan,SU Liang-Bi,ZHOU Guo-Qing
无机材料学报 , 2009, DOI: 10.3724/sp.j.1077.2009.00783
Abstract: R-plane sapphire used for epitaxial growth of non-polar GaN film was grown by the temperature gradient technique (TGT) method and chemical mechanical method was used to polish the r-plane sapphire substrate. The crystallization quality, optical property and surface roughness of as-obtained r-plane sapphire substrate were investigated. The average full width at half maximum (FWHM) of the substrate is 19.4arcsec and the dislocation density is 5.6 03cm-2. The transmission of the substrate is higher than 80% when the wavelength is longer than 300nm and the optical homogeneity is 6.6 0-5. The average surface roughness of the r-plane sapphire substrate is 0.49nm. The results indicate that as-obtained r-plane sapphire substrate meets the basic standard of GaN substrate.
A Review of Current Methodologies for Regional Evapotranspiration Estimation from Remotely Sensed Data
Zhao-Liang Li,Ronglin Tang,Zhengming Wan,Yuyun Bi,Chenghu Zhou,Bohui Tang,Guangjian Yan,Xiaoyu Zhang
Sensors , 2009, DOI: 10.3390/s90503801
Abstract: An overview of the commonly applied evapotranspiration (ET) models using remotely sensed data is given to provide insight into the estimation of ET on a regional scale from satellite data. Generally, these models vary greatly in inputs, main assumptions and accuracy of results, etc. Besides the generally used remotely sensed multi-spectral data from visible to thermal infrared bands, most remotely sensed ET models, from simplified equations models to the more complex physically based two-source energy balance models, must rely to a certain degree on ground-based auxiliary measurements in order to derive the turbulent heat fluxes on a regional scale. We discuss the main inputs, assumptions, theories, advantages and drawbacks of each model. Moreover, approaches to the extrapolation of instantaneous ET to the daily values are also briefly presented. In the final part, both associated problems and future trends regarding these remotely sensed ET models were analyzed to objectively show the limitations and promising aspects of the estimation of regional ET based on remotely sensed data and ground-based measurements.
Spatial and temporal distribution of falciparum malaria in China
Hualiang Lin, Liang Lu, Linwei Tian, Shuisen Zhou, Haixia Wu, Yan Bi, Suzanne C Ho, Qiyong Liu
Malaria Journal , 2009, DOI: 10.1186/1475-2875-8-130
Abstract: The annual numbers of falciparum malaria cases during 1992–2003 and the individual case reports of each clinical falciparum malaria during 2004–2005 were extracted from communicable disease information systems in China Center for Diseases Control and Prevention. The annual number of cases and the annual incidence were mapped by matching them to corresponding province- and county-level administrative units in a geographic information system. The distribution of falciparum malaria by age, gender and origin of infection was analysed. Time-series analysis was conducted to investigate the relationship between the falciparum malaria in the endemic provinces and the imported falciparum malaria in non-endemic provinces.Falciparum malaria was endemic in two provinces of China during 2004–05. Imported malaria was reported in 26 non-endemic provinces. Annual incidence of falciparum malaria was mapped at county level in the two endemic provinces of China: Yunnan and Hainan. The sex ratio (male vs. female) for the number of cases in Yunnan was 1.6 in the children of 0–15 years and it reached 5.7 in the adults over 15 years of age. The number of malaria cases in Yunnan was positively correlated with the imported malaria of concurrent months in the non-endemic provinces.The endemic area of falciparum malaria in China has remained restricted to two provinces, Yunnan and Hainan. Stable transmission occurs in the bordering region of Yunnan and the hilly-forested south of Hainan. The age and gender distribution in the endemic area is characterized by the predominance of adult men cases. Imported falciparum malaria in the non-endemic area of China, affected mainly by the malaria transmission in Yunnan, has increased both spatially and temporally. Specific intervention measures targeted at the mobile population groups are warranted.Malaria incidence appears to be decreasing worldwide as a result of mass interventions and other factors [1,2]. The decreasing pattern of incidence is encour
Diode-Pumped Soliton and Non-Soliton Mode-Locked Yb:GYSO Lasers

HE Jin-Ping,LIANG Xiao-Yan,LI Jin-Feng,ZHENG Li-He,SU Liang-Bi,XU Jun,

中国物理快报 , 2011,
Abstract:
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