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Search Results: 1 - 10 of 747351 matches for " Ben J. M. van de Wetering "
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Multifactorial Determinants of Target and Novelty-Evoked P300 Amplitudes in Children of Addicted Parents
Anja S. Euser, Brittany E. Evans, Kirstin Greaves-Lord, Ben J. M. van de Wetering, Anja C. Huizink, Ingmar H. A. Franken
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080087
Abstract: Background Although P300 amplitude reductions constitute a persistent finding in children of addicted parents, relatively little is known about the specificity of this finding. The major aim of this study was to investigate the association between parental rearing, adverse life events, stress-reactivity, substance use and psychopathology on the one hand, and P300 amplitude in response to both target and novel distracter stimuli on the other hand. Moreover, we assessed whether risk group status (i.e., having a parental history of Substance Use Disorders [SUD]) uniquely contributed to P300 amplitude variation above and beyond these other variables. Methods Event-related potentials were recorded in high-risk adolescents with a parental history of SUD (HR;n=80) and normal-risk controls (NR;n=100) while performing a visual Novelty Oddball paradigm. Stress-evoked cortisol levels were assessed and parenting, life adversities, substance use and psychopathology were examined by using self-reports. Results HR adolescents displayed smaller P300 amplitudes in response to novel- and to target stimuli than NR controls, while the latter only approached significance. Interestingly, the effect of having a parental history of SUD on target-P300 disappeared when all other variables were taken into account. Externalizing problem behavior was a powerful predictor of target-P300. In contrast, risk group status uniquely predicted novelty-P300 amplitude reductions above and beyond all other factors. Conclusion Overall, the present findings suggest that the P300 amplitude reduction to novel stimuli might be a more specific endophenotype for SUD than the target-P300 amplitude. This pattern of results underscores the importance of conducting multifactorial assessments when examining important cognitive processes in at-risk adolescents.
Trial Registration Numbers Are Underreported in Biomedical Publications
Fleur T. van de Wetering, Rob J. P. M. Scholten, Tamara Haring, Michael Clarke, Lotty Hooft
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0049599
Abstract: Context Since September 2005, the International Committee of Medical Journal Editors (ICMJE) has required that randomised controlled trials (RCTs) are prospectively registered in a publicly accessible database. After registration, a trial registration number (TRN) is assigned to each RCT, which should make it easier to identify future publications and cross-check published results with associated registry entries, as long as the unique identification number is reported in the article. Objective Our primary objective was to evaluate the reporting of trial registration numbers in biomedical publications. Secondary objectives were to evaluate how many published RCTs had been registered and how many registered RCTs had resulted in a publication, using a sample of trials from the Netherlands Trials Register (NTR). Design, Setting Two different samples of RCTs were examined: 1) RCTs published in November 2010 in core clinical journals identified in MEDLINE; 2) RCTs registered in the NTR with a latest expected end date of 31 August 2008. Results Fifty-five percent (166/302) of the reports of RCTs found in MEDLINE and 60% (186/312) of the published reports of RCTs from the NTR cohort contained a TRN. In both samples, reporting of a TRN was more likely in RCTs published in ICMJE member journals as compared to non-ICMJE member journals (MEDLINE 58% vs. 45%; NTR: 70% vs. 49%). Thirty-nine percent of published RCTs in the MEDLINE sample appear not to have been registered, and 48% of RCTs registered in the NTR seemed not to have been published at least two years after the expected date for study completion. Conclusion Our results show that further promotion and implementation of trial registration and accurate reporting of TRN is still needed. This might be helped by inclusion of the TRN as an item on the CONSORT checklist.
Probing photo-ionization: Experiments on positive streamers in pure gasses and mixtures
S Nijdam,F M J H van de Wetering,R Blanc,E M van Veldhuizen,U Ebert
Physics , 2009, DOI: 10.1088/0022-3727/43/14/145204
Abstract: Positive streamers are thought to propagate by photo-ionization whose parameters depend on the nitrogen:oxygen ratio. Therefore we study streamers in nitrogen with 20%, 0.2% and 0.01% oxygen and in pure nitrogen, as well as in pure oxygen and argon. Our new experimental set-up guarantees contamination of the pure gases to be well below 1 ppm. Streamers in oxygen are difficult to measure as they emit considerably less light in the sensitivity range of our fast ICCD camera than the other gasses. Streamers in pure nitrogen and in all nitrogen/oxygen mixtures look generally similar, but become somewhat thinner and branch more with decreasing oxygen content. In pure nitrogen the streamers can branch so much that they resemble feathers. This feature is even more pronounced in pure argon, with approximately 10^2 hair tips/cm^3 in the feathers at 200 mbar; this density could be interpreted as the free electron density creating avalanches towards the streamer stem. It is remarkable that the streamer velocity is essentially the same for similar voltage and pressure in all nitrogen/oxygen mixtures as well as in pure nitrogen, while the oxygen concentration and therefore the photo-ionization lengths vary by more than five orders of magnitude. Streamers in argon have essentially the same velocity as well. The physical similarity of streamers at different pressures is confirmed in all gases; the minimal diameters are smaller than in earlier measurements.
Predictors for Massive Haemorrhage during Caesarean Delivery Due to Placenta Praevia  [PDF]
Mara Burgers, Katrien Oude Rengerink, Sanne J. Eschbach, Moira M. Muller, Marielle G. van Pampus, Ben W. J. Mol, Irene M. de Graaf
International Journal of Clinical Medicine (IJCM) , 2015, DOI: 10.4236/ijcm.2015.62014
Abstract:
Objectives: To describe the incidence and predictive factors for massive haemorrhage during a caesarean delivery in women with placenta praevia. Methods: We performed a retrospective cohort study among consecutive women with a placenta praevia planned for a caesarean delivery between 2001-2011 in one academic centre and two teaching hospitals in the Netherlands. Massive haemorrhage was defined as ≥1000 mL blood loss during caesarean section. We used logistic regression analysis to assess which maternal and pregnancy characteristics were predictors for massive haemorrhage during caesarean delivery. Results: Of 54,794 deliveries, we identified 215 (0.39%) women with placenta praevia who underwent a Caesarean delivery, of whom 94 (44%) had massive haemorrhage at or after surgery. After univariable preselection, multivariable logistic regression indicated that higher maternal age (OR 2.09; 95% CI 1.17 - 3.74), no Caucasian ethnicity (OR 1.73; 95% CI 0.92 - 3.27), multiple pregnancy (OR 3.92; 95% CI 0.72 - 21.28), lower systolic blood pressure during pregnancy (OR 1.03; 95% CI 1.00 - 1.07) and the placenta located at the anterior wall (OR 2.21; 95% CI 1.20 - 4.04) were independent predictors for massive haemorrhage during a caesarean delivery in women with placenta praevia. Predicted probabilities varied between 22% and 71%. The model has a reasonable discriminative ability and acceptable calibration. Conclusions: Women with placenta praevia are at high risk for massive haemorrhage during caesarean delivery. The risk profile can be used to identify extreme high-risk women in whom extensive preventive measures are justified.
The Role of 18F-FDG-PET/CT in the Management of Patients with High-Risk Breast Cancer: Case Series and Guideline Comparison  [PDF]
Ben F. Bulten, Marie J. de Haas, Haiko J. Bloemendal, Adriaan J. van Overbeeke, Jan Paul Esser, Henk J. Baarslag, Lioe-Fee de Geus-Oei, C. J. Rodenburg, John M. H. de Klerk
Advances in Molecular Imaging (AMI) , 2014, DOI: 10.4236/ami.2014.43005
Abstract:
Objectives: In grade III-IV breast cancer, dissemination of disease needs to be assessed. Until now this was done by conventional imaging (liver ultrasonography, chest X-ray and bone scintigraphy), but evidence favoring the use of FDG-PET/CT is accumulating. Methods: Patients with high-risk breast cancer, who had received conventional imaging and FDG-PET/CT, were included. Patients were staged and assigned a treatment after 1) conventional imaging and 2) FDG-PET/CT, both by a multidisciplinary oncology team. Equivocal FDG-PET/CT findings were histologically confirmed. Results: 16 patients were included (mean age 59 years). TNM-stage changed in 5 patients (31%) after FDG-PET/CT. In 3 patients (19%) unknown distant metastases were detected by FDG-PET/CT. An adjustment of treatment took place in 4 patients (25%). Conclusions: Our case series emphasizes the role of FDG-PET/CT in the staging of high-risk breast carcinoma, especially in the assessment of distant metastases. We suggest replacing conventional imaging with FDG-PET/CT.
Quantifying Cost-Effectiveness of Controlling Nosocomial Spread of Antibiotic-Resistant Bacteria: The Case of MRSA
Marjan W. M. Wassenberg,G. Ardine de Wit,Ben A. van Hout,Marc J. M. Bonten
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0011562
Abstract: The costs and benefits of controlling nosocomial spread of antibiotic-resistant bacteria are unknown.
Book Reviews
M. Heerma van Voss,J. Vergote,W. Thoden van Velzen-van Wetering,Alan Harwood
Bijdragen tot de Taal-, Land- en Volkenkunde , 1973,
Abstract: - M. Heerma van Voss, J. Vergote, De godsdienst van de Egyptenaren. Romen, Roermond 1971. 125 p., plaat op omslag. - W. Thoden van Velzen-van Wetering, Alan Harwood, Witchcraft, sorcery and social categories among the Safwa. Oxford University Press for the International African Institute, London 1970. 160 p. - J.G. Oosten, E.E. Evans Pritchard, Nuer Religion, Clarendon Press, Oxford University Press, Oxford 1970. 335 p., 15 pl., 5 figs. - A.A. Trouwborst, Robert Brain, Bangwa Funerary Sculpture. Art and Society Series, Edited by Peter J. Ucko. Gerald Duckworth & Company Limited, London 1971, XII en 148 pp., plates, figures, colour plates., Adam Pollock (eds.) - A.A. Trouwborst, E.E. Evans-Pritchard, The Azande. History and political institutions. Oxford University Press, London 1971. 444 pages, maps, figures, plates. - John Beattie, Jack Goody, Technology, tradition and the state in Africa. Oxford University Press for the International African Institute, London 1971. 88 pp. - D.H. Reader, Mia Brandel-Syrier, Reeftown elite: A study of social mobility in a modern African community on the Reef. Routledge and Kegan Paul, London 1971. 335 p., 4 figs. - R. Buijtenhuijs, Ariane Deluz, Organisation sociale et tradition orale: Les Guro de C te d’Ivoire. Cahiers de l’Homme, Mouton et Co., Paris-La Haye 1970, 196 p. - John Beattie, Samwiri Rubaraza Karugire, A history of the Kingdom of Nkore in Western Uganda to 1896. Clarendon Press, Oxford Studies in African Affairs, Oxford 1971. 291 pp. - Jan Vansina, D.W. Cohen, The historical tradition of Busoga. Mukama and Kintu. (Oxford Studies in African Affairs), Clarendon Press: Oxford Univesity Press, Oxford 1972. Pp. X + 218, 9 kaartjes. - Th. Gerold-Scheepers, Alexander Alland jr., Adaptation in cultural evolution: an approach to medical anthropology. Columbia University Press, New York and London, 1970. IX + 188 p. and 6 p. bibliography. - J. Prins, Heribert Adam, South Africa. Sociological Perspectives. Oxford University Press, London-New York-Toronto-Cape Town, 1971. XII en 300 bladzijden tekst; elke bijdrage voorzien van een lijst van “references”; een bibliografie (blz. 301-332) en een index (blz. 333-340). - Wim van Zanten, Hugo Zemp, Musique Dan - La musique dans la pensée et la vie sociale d’une société africaine. Cahiers de l’Homme, Mouton, Paris 1971. 320 pages, 16 photographs. - Jan Knappert, W.H. Whiteley, Language use and social change, Problems of multilingualism with special reference to Eastern Africa. Published for the International African Institute by Oxford University Press, London 1970. 406 p. -
Systemic impairment in relation to disease burden in patients with moderate COPD eligible for a lifestyle program. Findings from the INTERCOM trial
Carel R van Wetering,Floortje E van Nooten,Stijn J M Mol,Martine Hoogendoorn
International Journal of COPD , 2008,
Abstract: Carel R van Wetering1, Floortje E van Nooten2, Stijn J M Mol3, Martine Hoogendoorn2, Maureen P M H Rutten-van M lken2, Annemie M Schols41Department of Physiotherapy, Máxima Medical Centre, Veldhoven, The Netherlands; 2Institute for Medical Technology Assessment, Erasmus Medical Centre, Rotterdam, The Netherlands; 3Department of Respiratory Medicine, Máxima Medical Centre, Veldhoven, The Netherlands; 4Department of Respiratory Medicine, Maastricht University, Maastricht, The NetherlandsIntroduction: In contrast with the frequency distribution of chronic obstructive pulmonary disease (COPD) stages in the population, in which the majority of the patients is classified as GOLD 2, much less information is available on the prevalence and implications of systemic manifestations in less severe patients relative to GOLD 3 and 4.Aim: To characterize local and systemic impairment in relation to disease burden in a group of GOLD 2 COPD patients (n = 127, forced expiratory volume in one second (SD): 67 (11)% pred) that were eligible for the Interdisciplinary Community-based COPD management (INTERCOM) trial.Methods: Patients were included for this lifestyle program based on a peak exercise capacity (Wmax) <70% of predicted. Metabolic and ventilatory response to incremental cycle ergometry, 6 minute walking distance (6MWD), constant work rate test (CWR), lung function, maximal inspiratory pressure (Pimax), quadriceps force (QF), quadriceps average power (QP) (isokinetic dynamometry), handgrip force (HGF) and body composition were measured. Quality of life (QoL) was assessed by the St. George’s Respiratory Questionnaire (SGRQ) and dyspnea by the modified Medical Research Council (MRC) dyspnea scale. Exacerbations and COPD-associated hospital admissions in 12 months prior to the start of the study were recorded. Burden of disease was defined in terms of exercise capacity, QoL, hospitalization, and exacerbation frequency. GOLD 2 patients were compared with reference values and with GOLD 3 patients who were also included in the trial.Results: HGF (77.7 (18.8) % pred) and Pimax (67.1 (22.5)% pred) were impaired in GOLD 2, while QF (93.5 (22.5)% pred) was only modestly decreased. Depletion of FFM was present in 15% of weight stable GOLD 2 patients while only 2% had experienced recent involuntary weight loss. In contrast to Wmax, submaximal exercise capacity, muscle function, and body composition were not significantly different between GOLD 2 and 3 subgroups. Body mass index and fat-free mass index were significantly lower in smokers compared to ex-smokers. In multivariate
Reversible Electric-Field Driven Magnetic Domain Wall Motion
Kévin J. A. Franke,Ben Van de Wiele,Yasuhiro Shirahata,Sampo J. H?m?l?inen,Tomoyasu Taniyama,Sebastiaan van Dijken
Physics , 2014,
Abstract: Control of magnetic domain wall motion by electric fields has recently attracted scientific attention because of its potential for magnetic logic and memory devices. Here, we report on a new driving mechanism that allows for magnetic domain wall motion in an applied electric field without the concurrent use of a magnetic field or spin-polarized electric current. The mechanism is based on elastic coupling between magnetic and ferroelectric domain walls in multiferroic heterostructures. Pure electric-field driven magnetic domain wall motion is demonstrated for epitaxial Fe films on BaTiO$_3$ with in-plane and out-of-plane polarized domains. In this system, magnetic domain wall motion is fully reversible and the velocity of the walls varies exponentially as a function of out-of-plane electric field strength.
The Relationship of Objectively Measured Physical Activity and Sedentary Behaviour with Gestational Weight Gain and Birth Weight
Anneloes E. Ruifrok,Ellen Althuizen,Nicolette Oostdam,Willem van Mechelen,Ben Willem Mol,Christianne J. M. de Groot,Mireille N. M. van Poppel
Journal of Pregnancy , 2014, DOI: 10.1155/2014/567379
Abstract: Objective. To evaluate the relationship of physical activity (PA) and sedentary behaviour with gestational weight gain (GWG) and birth weight. Design. Combined data from two prospective studies: (1) nulliparous pregnant women without BMI restrictions and (2) overweight and obese pregnant women at risk for gestational diabetes. Methods. Daily PA and sedentary behaviour were measured with an accelerometer around 15 and at 32–35 weeks of gestation. The association between time spent in moderate-to-vigorous PA (MVPA) and in sedentary activities with GWG and birth weight was determined. Main outcome measures were GWG between 15 and 32 weeks of gestation, average GWG per week, and birth weight. Results. We studied 111 women. Early in pregnancy, 32% of women spent ≥30 minutes/day in at least moderate PA versus 12% in late pregnancy. No significant associations were found between time spent in MVPA or sedentary behaviour with GWG or birth weight. Conclusions. We found no relation between MVPA and sedentary behaviour with GWG or birth weight. The small percentage of women meeting the recommended levels of PA indicates the need to inform and support pregnant women to maintain regular PA, as there seems to be no adverse effect on birth weight and maintaining PA increases overall health. 1. Introduction Excessive weight gain during pregnancy is associated with an increased risk of obstetrical, maternal, and fetal complications [1–4] and postpartum weight retention [5]. It increases the risk of obesity in children [5–7]. This contributes to the prevalence of women who are overweight or obese and increases the long-term risk of body weight-associated diseases, which impose a great pressure on health care [5, 8–12]. The American Institute of Medicine (IOM) updated their evidence-based guidelines for weight development during pregnancy in 2009 [13]. However, 53% of all women gain more weight than advised by the IOM. This is even more pronounced in women with overweight or obesity, with 68.9% and 59.8%, respectively, exceeding the recommendations [14]. Many trials have been conducted evaluating the effect of different lifestyle interventions on gestational weight gain (GWG) and adverse pregnancy outcomes, which were recently reviewed and combined in a meta-analysis [15, 16]. Combining results of 15 interventions consisting of physical activity (PA) alone did not result in a statistically significant effect on GWG and showed a very small but statistically significant reduction in mean birth weight. However, it must be noted that the compliance with the interventions was
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