oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2020 ( 2 )

2019 ( 190 )

2018 ( 248 )

2017 ( 270 )

Custom range...

Search Results: 1 - 10 of 190047 matches for " Barclay G. Barrell "
All listed articles are free for downloading (OA Articles)
Page 1 /190047
Display every page Item
甲状腺功能对调节雄性马鹿体重和繁殖活动季节性变化的研究
施振旦,g.k.barrell
兽类学报 , 1995,
Abstract: ?本研究探讨了甲状腺功能对雄性马鹿体重和繁殖活动季节性变化的调节作用。试验1从1988年1月(夏季)开始到1989年6月(冬季)结束,对照组5头正常鹿体中,血浆t3水平具有明显的季节性变化(p3水平在1988年6月后(冬季)降低到不可测水平。在1988年9月以前,二组鹿的体重、睾丸直径和血浆睾酮水平的季节性变化趋势相似。正常鹿体重在1988年l2月至1989年3月(夏秋季)大大增加,而thx鹿体重仅有少许增长。在1988年9月(春季)开始,正常鹿睾丸萎缩,血浆睾酮水平也下降至不可测水平,thx鹿则未发生此现象,但在thx鹿在秋季配种季节的睾丸直径峰值剜叉显著低于正常鹿的值。试验2从1990年9月(春季)开始,对4头thx雄性马鹿补偿t4,另外4头thx雄性马鹿作为对照,于1991年3月结束。在整个春夏季生长季节,t4补偿鹿增重高于对照鹿(p4也使thx鹿的睾丸在春夏季发生萎缩退化,血浆睾酮水平在春夏季降至不可测定。两试验的结果表明,甲状腺功能参与雄性马鹿在春夏季的体重和繁殖活动季节性变化的调节。
Rapid Evolution of Virulence and Drug Resistance in the Emerging Zoonotic Pathogen Streptococcus suis
Matthew T. G. Holden, Heidi Hauser, Mandy Sanders, Thi Hoa Ngo, Inna Cherevach, Ann Cronin, Ian Goodhead, Karen Mungall, Michael A. Quail, Claire Price, Ester Rabbinowitsch, Sarah Sharp, Nicholas J. Croucher, Tran Bich Chieu, Nguyen Thi Hoang Mai, To Song Diep, Nguyen Tran Chinh, Michael Kehoe, James A. Leigh, Philip N. Ward, Christopher G. Dowson, Adrian M. Whatmore, Neil Chanter, Pernille Iversen, Marcelo Gottschalk, Josh D. Slater, Hilde E. Smith, Brian G. Spratt, Jianguo Xu, Changyun Ye, Stephen Bentley, Barclay G. Barrell, Constance Schultsz, Duncan J. Maskell, Julian Parkhill
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0006072
Abstract: Background Streptococcus suis is a zoonotic pathogen that infects pigs and can occasionally cause serious infections in humans. S. suis infections occur sporadically in human Europe and North America, but a recent major outbreak has been described in China with high levels of mortality. The mechanisms of S. suis pathogenesis in humans and pigs are poorly understood. Methodology/Principal Findings The sequencing of whole genomes of S. suis isolates provides opportunities to investigate the genetic basis of infection. Here we describe whole genome sequences of three S. suis strains from the same lineage: one from European pigs, and two from human cases from China and Vietnam. Comparative genomic analysis was used to investigate the variability of these strains. S. suis is phylogenetically distinct from other Streptococcus species for which genome sequences are currently available. Accordingly, ~40% of the ~2 Mb genome is unique in comparison to other Streptococcus species. Finer genomic comparisons within the species showed a high level of sequence conservation; virtually all of the genome is common to the S. suis strains. The only exceptions are three ~90 kb regions, present in the two isolates from humans, composed of integrative conjugative elements and transposons. Carried in these regions are coding sequences associated with drug resistance. In addition, small-scale sequence variation has generated pseudogenes in putative virulence and colonization factors. Conclusions/Significance The genomic inventories of genetically related S. suis strains, isolated from distinct hosts and diseases, exhibit high levels of conservation. However, the genomes provide evidence that horizontal gene transfer has contributed to the evolution of drug resistance.
A Deconstruction of Borderline Personality Disorder  [PDF]
Michael Barclay
Psychology (PSYCH) , 2015, DOI: 10.4236/psych.2015.69117
Abstract: BPD is a disorder of many aspects, levels, meanings, presenting symptoms and issues. It demands deconstruction so that the blueprint of its development can provide a model for its treatment. Deconstruction can only be accomplished theoretically. This paper attempts to provide a theoretical perspective on both the development of the syndrome and a possible view of its treatment. The paper reviews the theories of BLPD and the steady reification of the diagnosis in order to provide a phenomenological alternative and a compassionate method of treatment.
RELATIONSHIP BETWEEN PETROGRAPHIC PORE TYPES AND CORE MEASUREMENTS IN SANDSTONES OF THE MONSERRATE FORMATION, UPPER MAGDALENA VALLEY, COLOMBIA
EHRLICH,R; COBALEDA,G; BARCLAY FERM,J;
CT&F - Ciencia, Tecnología y Futuro , 1997,
Abstract: patterns of porosity in sandstones of the monserrate formation (upper magdalena valley) exposed in polished blocks have been digitally recorded using an image processor coupled to a scanning electron microscope operated in backscatter electron mode. additionally, porosity, permeability and response to mercury injection-capillary pressure tests were measured on some of the imaged samples. porosity patterns were evaluated via an erosion/dilation-differencing image-processing algorithm and then classified by the selftraining classifier, sawvec. changes in the resulting pore type proportions were strongly associated with changes in the mercury porosimetry curves. from the image processing data, five pore types, sufficient to include all of the variability in size and shape of the patterns of porosity, were identified. variations in the number of pores of each type per unit cross sectional area were related to variations in permeability. the resultant relationships with mercury porosimetry demonstrated that pores of the same type tend to form microcircuits characterized by a limited throat size range. permeability modeling showed that intergranular pore types 2 and 4 (secondary porosity resulting from carbonate dissolution) are responsible for permeability in the 0,01 -0,1 0 darcy range. type 5 pores (large molds) slightly contribute to permeability, except in coarse grained rocks where they are efficiently connected by microfractures.
RELATIONSHIP BETWEEN PETROGRAPHIC PORE TYPES AND CORE MEASUREMENTS IN SANDSTONES OF THE MONSERRATE FORMATION, UPPER MAGDALENA VALLEY, COLOMBIA
R EHRLICH,G COBALEDA,J BARCLAY FERM
CT&F - Ciencia, Tecnología y Futuro , 1997,
Abstract: Patterns of porosity in sandstones of the Monserrate Formation (Upper Magdalena Valley) exposed in polished blocks have been digitally recorded using an image processor coupled to a scanning electron microscope operated in backscatter electron mode. Additionally, porosity, permeability and response to mercury injection-capillary pressure tests were measured on some of the imaged samples. Porosity patterns were evaluated via an erosion/dilation-differencing image-processing algorithm and then classified by the selftraining classifier, SAWVEC. Changes in the resulting pore type proportions were strongly associated with changes in the mercury porosimetry curves. From the image processing data, five pore types, sufficient to include all of the variability in size and shape of the patterns of porosity, were identified. Variations in the number of pores of each type per unit cross sectional area were related to variations in permeability. The resultant relationships with mercury porosimetry demonstrated that pores of the same type tend to form microcircuits characterized by a limited throat size range. Permeability modeling showed that intergranular Pore Types 2 and 4 (secondary porosity resulting from carbonate dissolution) are responsible for permeability in the 0,01 -0,1 0 Darcy range. Type 5 pores (large molds) slightly contribute to permeability, except in coarse grained rocks where they are efficiently connected by microfractures. Patrones de porosidad de areniscas pertenecientes a la Formación Monserrate (Valle Superior del Magdalena), expuestos sobre bloques pulidos, fueron capturados y digitalizados mediante procesador de imágenes acoplado al Microscopio Electrónico de Barrido operado en detección de electrones retrodispersos. Adicionalmente se midieron la porosidad y permeabilidad, y se realizó porosimetría de mercurio. Los patrones de porosidad se evaluaron por algoritmos de procesamiento que hacen uso de diferenciación vía erosión/dilatación, y posteriormente fueron clasificados mediante el programa SAWVEC. A partir del procesamiento se establecieron cinco tipos de poro, suficientes para describir toda la variabilidad en tama o y forma del espacio poral en estudio. Variaciones en el número de poros de cada tipo por unidad de área transversal se relacionaron con la permeabilidad. La relación resultante con la porosimetría de mercurio demostró que poros de un mismo tipo tienden a formar microcircuitos caracterizados por un tama o de garganta restringido. El modelo de permeabilidad demostró que los poros intergranulares tipo 2 y 4 (porosidad regenera
The importance of early arthroscopy in athletes with painful cartilage lesions of the ankle: a prospective study of 61 consecutive cases
Christer G Rolf, Caroline Barclay, Masoud Riyami, John George
Journal of Orthopaedic Surgery and Research , 2006, DOI: 10.1186/1749-799x-1-4
Abstract: Primarily to evaluate clinical symptoms, signs, diagnostics and outcomes of surgery for symptomatic chondral injuries of the talo crural joint in athletes. Secondly, in applicable cases, to evaluate the accuracy of MRI in detecting these injuries. Type of study: Prospective consecutive series.Over around 4 years we studied 61 consecutive athletes with symptomatic chondral lesions to the talocrural joint causing persistent exertion ankle pain.43% were professional full time athletes and 67% were semi-professional, elite or amateur athletes, main sports being soccer (49%) and rugby (14%). The main subjective complaint was exertion ankle pain (93%). Effusion (75%) and joint line tenderness on palpation (92%) were the most common clinical findings. The duration from injury to arthroscopy for 58/61 cases was 7 months (5.7–7.9). 3/61 cases were referred within 3 weeks from injury. There were in total 75 cartilage lesions. Of these, 52 were located on the Talus dome, 17 on the medial malleolus and 6 on the Tibia plafond. Of the Talus dome injuries 18 were anteromedial, 14 anterolateral, 9 posteromedial, 3 posterolateral and 8 affecting mid talus. 50% were grade 4 lesions, 13.3% grade 3, 16.7% grade 2 and 20% grade 1. MRI had been performed pre operatively in 26/61 (39%) and 59% of these had been interpreted as normal. Detection rate of cartilage lesions was only 19%, but subchondral oedema was present in 55%. At clinical follow up average 24 months after surgery (10–48 months), 73% were playing at pre-injury level. The average return to that level of sports after surgery was 16 weeks (3–32 weeks). However 43% still suffered minor symptoms.Arthroscopy should be considered early when an athlete presents with exertion ankle pain, effusion and joint line tenderness on palpation after a previous sprain. Conventional MRI is not reliable for detecting isolated cartilage lesions, but the presence of subchondral oedema should raise such suspicion.Ankle injuries make up 15% of all s
Review of Keenan, Jeremy 2001. Sahara Man, Travelling with the Tuareg. London: John Murray
Rupert Barclay
Papers from the Institute of Archaeology , 2001, DOI: 10.5334/pia.418
Abstract:
Employee Change Agents: The Foundation for Effective Organizational Change
Allen Barclay
International Business Research , 2009, DOI: 10.5539/ibr.v2n4p3
Abstract: This paper specifically looks at the process of organizational change and how employees can influence the outcomes. Organizations tend to underutilize their employees during times of change. An organization is basically a collection of people with the same objectives. Ultimately, I seek to understand how an employee change agent framework can function as an essential tool for controlling and analyzing organizational change. As a manager and an instructor of management, I believe that is the employee that essentially controls the success of any change in an organization. Employees should be charged with the ability to foster positive change by management, but more so, by themselves. It is the employees responsibility to make the change work in the organization, along with making changes in themselves to help improve not only the organization, but to improve their own working behaviors. All employers should be creating a learning organization by asking their employees to become responsible members of the organization. Allow your staff to be present at the table. Also empower your staff to become more aligned with the core mission of the organization. The more your staff believes they are making a difference for the organization, the more vested, accountable, and responsible they will become.
Cambios y continuidades en el pacto colonial en la Amazonía: el caso de los indios chasutas del Huallaga medio a finales del siglo XIX
Barclay, Frederica
Bulletin de l'Institut Francais d'études Andines , 2001,
Abstract: CHANGEMENTS ET CONTINUITES DU PACTE COLONIAL EN AMAZONIE. LE CAS DES INDIENS CHASUTAS DU MOYEN HUALLAGA A LA FIN DU XIXe SIECLE. Cet article analyse le soulèvement Chasuta de 1893 dans la région du moyen Huallaga, comme résultat de ce que les indigènes per urent comme une rupture du pacte colonial qui leur assurait certains droits et privilèges et établissait leurs devoirs envers l état. L article suggère que la dissolution de cet ordre d origine missionnaire entra na la désintégration sociale des Chasutas et accéléra ainsi les processus mis en place par le boom du caoutchouc. Este artículo analiza el levantamiento chasuta ocurrido en 1893 en el Medio Huallaga, como el resultado de lo que los indígenas locales percibieron como la ruptura del pacto colonial que les garantizaba determinados derechos y prerrogativas y establecía sus obligaciones frente al Estado. Sugiere que la disolución de este ordenamiento de origen misional y colonial, condujo a la desintegración social de los llamados chasutas y aceleró los procesos impulsados por el auge gomero. CHANGES AND CONTINUITIES IN THE COLONIAL PACT IN AMAZONIA. THE CASE OF CHASUTA AT THE END OF 19TH CENTURY. This article explains the occurrence of an uprising in Chasuta in 1893 as the result of what local Indians perceived as the infringement of the colonial pact that guarantied their rights and stipulated their duties vis à vis the local administration. It suggests that the dissolution of such a pact led to the social disintegration of the Chasuta as a people and that it accelerated those processes driven by the rubber boom.
The Rich Structure of Gauss-Bonnet Holographic Superconductors
Luke Barclay
Physics , 2010, DOI: 10.1007/JHEP10(2011)044
Abstract: We study fully backreacting, Gauss-Bonnet (GB) holographic superconductors in 5 bulk spacetime dimensions. We explore the system's dependence on the scalar mass for both positive and negative GB coupling, $\alpha$. We find that when the mass approaches the Breitenlohner-Freedman (BF) bound and $\alpha\rightarrow L^2/4$ the effect of backreaction is to increase the critical temperature, $T_c$, of the system: the opposite of its effect in the rest of parameter space. We also find that reducing $\alpha$ below zero increases $T_c$ and that the effect of backreaction is diminished. We study the zero temperature limit, proving that this system does not permit regular solutions for a non-trivial, tachyonic scalar field and constrain possible solutions for fields with positive masses. We investigate singular, zero temperature solutions in the Einstein limit but find them to be incompatible with the concept of GB gravity being a perturbative expansion of Einstein gravity. We study the conductivity of the system, finding that the inclusion of backreaction hinders the development of poles in the conductivity that are associated with quasi-normal modes approaching the real axis from elsewhere in the complex plane.
Page 1 /190047
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.