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Replacement of Process Scale Chromatography by Counterflow Membrane Cascades  [PDF]
Edwin N. Lightfoot, Bar?? ünal
Advances in Bioscience and Biotechnology (ABB) , 2014, DOI: 10.4236/abb.2014.511106
Abstract: Invention and innovation, always important, become ever more so in these fast changing and competitive times. They are in addition primarily dependent upon the dynamic behavior of the human mind. Our underlying purpose here is to examine these creative processes and to provide means to make them more effective. This is a timely effort because our understanding of perception and its interpretation by the human brain is very rapidly advancing. Even experimental insights into mental activity can be determined with rapidly increasing effectiveness. The framework of our discussion is that of evolution dynamics, and the scientific bases are rapidly developing neural sciences. However the bulk of our discussion deals with a specific example: the replacement of process scale chromatography by membrane-mediated steady counterflow in downstream processing. We do this because inventive activities must depend upon intimate knowledge of the systems available.
Early detection of pulmonary fungal infection by CT scan in pediatric ALL patients under chemotherapy or in post-transplantation period with primary complaint of chest pain
?ule ünal,Bar?? Ku?konmaz,Betul Tavil,Selin Ayta? Elmas
Turkish Journal of Hematology , 2010,
Abstract: We describe herein four children with acute lymphoblastic leukemia who were diagnosed as pulmonary fungal infection after presenting with chest pain. The plain radiologic evaluations failed to reveal any positive findings, whereas computerized tomography (CT) scanning showed nodular opacification with or without cavitation. This experience suggests that chest pain may be an initial symptom of an invasive fungal infection in patients with leukemia, and CT scan of the lungs should be performed urgently for the early diagnosis and treatment, despite normal plain X-rays.
Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants
?ule ünal,Bar?? Ku?konmaz,Necati Balamtekin,G?khan Baysoy
Turkish Journal of Hematology , 2010,
Abstract: Giant cell hepatitis associated with direct Coombs’ test-positive hemolytic anemia is a rare condition of childhood and the pathogenesis remains unclear. An autoimmune activation and loss of self-tolerance in these patients may be the underlying pathology related to the response of some of the patients to immunosuppressive treatment. Herein, we report the clinical presentation and course of three consecutive patients with this rare condition. We conclude that serum ferritin at diagnosis may be used for prediction of the outcome.
China and Sub-Saharan Africa’s Economic Development: A Multipolar Specification  [PDF]
Abdelrasaq Nal
Technology and Investment (TI) , 2015, DOI: 10.4236/ti.2015.63015
Abstract: Within the purview of contemporary international development discourse, China, alongside other regional powers are perceived as growth poles or drivers of global development. In the context of Africa’s development around which some of the emergent issues have been framed, analyses often proceed along a bilateral framework where the influence of China is isolated and assumed to be neither connected with nor shaped by the influences of other growth poles. Inspired by recent development in policy circles, this paper develops a multipolar framework to explain ways by which dimensions of possible interactions amongst activities of growth poles can affect development outcomes in other regions. It is then used to demonstrate how a nexus of Sino-EU activities has had limited impact on the development of Africa’s manufactured exports in comparison with similar nexus involving China and US.
An unusual presentation of pediatric acute lymphoblastic leukemia with parotid gland involvement and dactylitis
?ule ünal,Bar?? Ku?konmaz,Yasemin I??k Balc?,Bülent Cengiz
Turkish Journal of Hematology , 2010,
Abstract: Mumps infection during the course of childhood acute lymphoblastic leukemia (ALL) treatment has been reported to have a mild course and this was related to the intrinsic low cytopathological effect of the virus, contrasting with the severe course of measles and Varicella zoster virus infections in immunocompromised patients. Herein, we present a three-year-old girl, who was previously vaccinated against mumps infection, admitted with bilateral parotid swelling, dactylitis and serum immunoglobulin M positivity for mumps infection and diagnosed to have ALL with bilateral persistent parotid involvement, inconsistent with mumps infection. Acute leukemia should be suspected during the atypical course of any disease during childhood. Besides, mumps infection at presentation of ALL, as similar to infection emerging during the period of the leukemia treatment, has a mild course.
Longitudinal Study of Cognitive Impairment in Multiple Sclerosis: A 5-year Follow-up
Demet Yand?m Ku??u,Melek Kandemir,Aysun ünal,Bar?? Top?ular
N?ropsikiyatri Ar?ivi , 2012,
Abstract: Objectives: Cognitive impairment can be demonstrated in 40 to 65% of MS patients, starting from early stages. The aim of this study was to investigate alteration in cognitive impairment during long-term follow-up and the association with the disease characteristics.Method: Twenty-five MS patients (15 men, 10 women) were reexamined after an average of 5.3 years (range: 4.9-5.8). The disease duration, type, Expanded Disability Status Scale (EDSS) scores at the initial and last evaluations were recorded. They underwent a comprehensive neuropsychological evaluation. Major depression was excluded.Results: The mean age of the patients was 39.2±9.3 years and the mean duration of the disease was 11.4±5.14 years. The mean EDSS score at the beginning and last follow-up were 2.92±1.52 and 3.56±1.92, respectively. At the end of the follow-up period, the patients performed poorly on the Corsi Block-Tapping Test (p<0.001) and there was a significant difference in maximum word line in the verbal memory processes test (VMPT) (p<0.001). Short-term memory scores, assessed with the Wechsler Memory Scale (WMS), decreased slightly, but the total recall score was significantly worse (p<0.001). There was also significant decrease in executive functions according to the stroop test (p<0.001), and the Wisconsin Card Sorting Test (WCST) results in patients with a longer disease course were worse. Besides, there was a trend for worsening in the clock-drawing test. The language skills were well preserved. Patients with a disease duration of ≥10 years scored worse on the stroop test, clock-drawing test, Benton Line Orientation Test (BLOT), WCST, and VMPT. Discussion: The cognitive deficits tended to worsen during long-term follow-up. There was no correlation between severity of disability and cognitive impairment. However, there seems to be an association between results of some tests and disease duration. (Arc-hi-ves of Neu-ropsy-chi-atry 2012;49: 29-32)
Zafer ünal,Aslihan ünal
International Journal of Instruction , 2012,
Abstract: This study provided a basis for answering the following essential question: Does the years of experience affect teachers' classroom management approaches? Data were collected from 268 primary school teachers. The findings of this study demonstrated that experienced teachers are more likely to prefer to be in control in their classrooms than beginning teachers while interacting with students when making decisions. Investigating the previous studies, researchers were able to discover that there is certain path teachers follow through their career. While preservice teachers prefer non-interventionism (minimum teacher control), they support interactionism (shared control) during internship and early career years, and finally they prefer to choose complete teacher control when they become experienced teachers.
A case study on the perception of the school counselor by students and teachers
Ali ünal,Emine ünal
International Journal of Human Sciences , 2010,
Abstract: The aim of this research is to determine the perception of the school counsellor of the school by teachers working at a formal general high school and students, via metaphors. In the research, one of the case study patterns, an embedded single-case design was used. Study group of the research consists of 89 students studying at eleventh grade at a high school in Sel uklu district in 2007-2008 academic years, of Konya and 25 teachers working at this school. Data were collected by open ended survey method. In the survey, participants were asked to complete the sentence "School Counselor is like ... because ...". Data were analysed using content analysis method. According to the findings, the school counselor is acting according to the guidance principles and he is devoted to his profession. While the students' remarks were about his professional characteristics, teachers' remarks were about his personal characteristics.
Fourier Coefficients of a Class of Eta Quotients of Weight 16 with Level 12  [PDF]
Bar?? Kendirli
Applied Mathematics (AM) , 2015, DOI: 10.4236/am.2015.68133
Abstract: Recently, Williams [1] and then Yao, Xia and Jin [2] discovered explicit formulas for the coefficients of the Fourier series expansions of a class of eta quotients. Williams expressed all coefficients of 126 eta quotients in terms of \"\" and \"\" and Yao, Xia and Jin, following the method of proof of Williams, expressed only even coefficients of 104 eta quotients in terms of \"\" and \"\" . Here, by using the method of proof of Williams, we will express the even Fourier coefficients of 360 eta quotients i.e., the Fourier coefficients of the sum, f(q) + f(?q), of 360 eta quotients in terms of \"\" and \"\".
Representations by Certain Sextenary Quadratic Forms Whose Coefficients Are 1, 2, 3 and 6  [PDF]
Bar?? Kendirli
Advances in Pure Mathematics (APM) , 2016, DOI: 10.4236/apm.2016.64018
Abstract: Here, we determine formulae, for the numbers of representations of a positive integer by certain sextenary quadratic forms whose coefficients are 1, 2, 3 and 6.
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