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Search Results: 1 - 10 of 321 matches for " Baljean Dhillon "
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Postoperative IOP prophylaxis practice following uncomplicated cataract surgery: a UK-wide consultant survey
Usha Zamvar, Baljean Dhillon
BMC Ophthalmology , 2005, DOI: 10.1186/1471-2415-5-24
Abstract: A questionnaire was sent to all consultant ophthalmic surgeons in the UK.62.6% of surgeons did not use any IOP lowering agents. 37.4% surgeons routinely prescribed some form of medication. The majority (86.8%) used oral diamox. 20.6% of surgeons said they based their practice on evidence, 43.3% on personal experience, and 17.6% on unit policy. Surprisingly, among the two groups of surgeons (those who gave routine prophylaxis, and those who did not) the percentages of surgeons quoting personal experience, unit policy, or presence of evidence was strikingly similar. The timing of the first postoperative IOP check varied from the same day to beyond 2 weeks. Only 20.2% of surgeons had ever seen an adverse event related to IOP rise; this complication is thus very rare.This survey highlights a wide variation in the practice and postoperative management of phacoemulsification cataract surgery. What is very striking is that there is a similar proportion of surgeons in the diametrically opposite groups (those who give or do not give routine IOP lowering prophylaxis) who believe that there practice is evidence based. The merits of this study suggests that consideration must be given to drafting a uniform guideline in this area of practice.Phacoemulsification and intra-ocular lens implantation (PhIOL) is one of the most cost-effective, elective surgical interventions. In order to minimise postoperative intraocular pressure (IOP) rise, prophylaxis may be adopted. Currently, there are no specific guidelines for prophylaxis in uncomplicated cataract surgery. We studied current prophylaxis practice in a UK-wide survey which showed wide variation in prophylaxis practice.We conducted a pilot, self-administered postal-based survey of the Scottish ophthalmic consultants. The results of this survey suggested variation in prophylaxis practice for IOP rise, duration until 1st IOP monitoring, and management of elevated IOP following uncomplicated phacoemulsification with intraocular lens
Does a small central Nd:YAG posterior capsulotomy improve peripheral fundal visualisation for the Vitreoretinal surgeon?
Niall Patton, Tariq M Aslam, Harry G Bennett, Baljean Dhillon
BMC Ophthalmology , 2004, DOI: 10.1186/1471-2415-4-8
Abstract: Patients undergoing Nd:YAG capsulotomy for PCO were examined pre- and four weeks post- Nd:YAG capsulotomy. In order to give a quantitative measure of visualisation of the peripheral retina, a novel scalar measurement was developed. Changes in the degree of visualisation following Nd:YAG capsulotomy were calculated.There was a significant improvement in fundal visualisation of the retinal periphery with scleral indentation following Nd:YAG capsulotomy (p = 0.001).Peripheral fundal visualisation with scleral indentation improves following a small central Nd:YAG capsulotomy. This finding is important in relation to the detection of peripheral pseudophakic retinal breaks, particularly in those patients deemed at high risk following Nd:YAG capsulotomy.Posterior capsular opacification (PCO) is the commonest complication of cataract surgery [1]. It has implications not only for the immediate visual function of the patient, but also for the ophthalmologists' diagnostic ability, as PCO may have a significant impact on the ability of the vitreoretinal surgeon to visualise the peripheral fundus. This may be particularly important for patients at risk of retinal detachment.After uneventful extracapsular cataract surgery, Nd:YAG capsulotomy has been shown to increase the risk of developing a retinal detachment [2-11]. Proposed mechanisms include liquefaction of the vitreous[12] and interruption of the anterior hyaloid face[13]. Whilst some authors consider the increased risk to be as a result of opening the capsule and not a specific complication of the laser procedure itself[10,12,14], minimising the energy used to create the capsulotomy is generally considered advisable to minimise the associated risk of retinal detachment[15]. It has been suggested that current practise should be wary of performing Nd:YAG capsulotomy on high risk patients, such as high myopes. However when making this decision, one must also consider that there may be an increased difficulty in fundal visuali
Increased Corneal Epithelial Turnover Contributes to Abnormal Homeostasis in the Pax6+/? Mouse Model of Aniridia
Panagiotis Douvaras, Richard L. Mort, Dominic Edwards, Kanna Ramaesh, Baljean Dhillon, Steven D. Morley, Robert E. Hill, John D. West
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0071117
Abstract: We aimed to test previous predictions that limbal epithelial stem cells (LESCs) are quantitatively deficient or qualitatively defective in Pax6+/? mice and decline with age in wild-type (WT) mice. Consistent with previous studies, corneal epithelial stripe patterns coarsened with age in WT mosaics. Mosaic patterns were also coarser in Pax6+/? mosaics than WT at 15 weeks but not at 3 weeks, which excludes a developmental explanation and strengthens the prediction that Pax6+/? mice have a LESC-deficiency. To investigate how Pax6 genotype and age affected corneal homeostasis, we compared corneal epithelial cell turnover and label-retaining cells (LRCs; putative LESCs) in Pax6+/? and WT mice at 15 and 30 weeks. Limbal BrdU-LRC numbers were not reduced in the older WT mice, so this analysis failed to support the predicted age-related decline in slow-cycling LESC numbers in WT corneas. Similarly, limbal BrdU-LRC numbers were not reduced in Pax6+/? heterozygotes but BrdU-LRCs were also present in Pax6+/? corneas. It seems likely that Pax6+/? LRCs are not exclusively stem cells and some may be terminally differentiated CD31-positive blood vessel cells, which invade the Pax6+/? cornea. It was not, therefore, possible to use this approach to test the prediction that Pax6+/? corneas had fewer LESCs than WT. However, short-term BrdU labelling showed that basal to suprabasal movement (leading to cell loss) occurred more rapidly in Pax6+/? than WT mice. This implies that epithelial cell loss is higher in Pax6+/? mice. If increased corneal epithelial cell loss exceeds the cell production capacity it could cause corneal homeostasis to become unstable, resulting in progressive corneal deterioration. Although it remains unclear whether Pax6+/? mice have LESC-deficiency, we suggest that features of corneal deterioration, that are often taken as evidence of LESC-deficiency, might occur in the absence of stem cell deficiency if corneal homeostasis is destabilised by excessive cell loss.
Balancing Scales of Language Injustice  [PDF]
Jerome Rabow, Manpreet Dhillon
Sociology Mind (SM) , 2015, DOI: 10.4236/sm.2015.51003
Abstract: This paper addresses the ways in which our everyday usage of the common phrase “people of color” perpetuates a basic inequality in language use. A suggestion to eliminate inequality in teaching is proposed.
Probabilistic Analysis of a Robot System with Redundant Safety Units and Common-Cause Failures  [PDF]
B. S. DHILLON, Zhijian LI
Intelligent Information Management (IIM) , 2009, DOI: 10.4236/iim.2009.13022
Abstract: This paper presents reliability and availability analyses of a model representing a system having one robot and n-redundant safety units with common-cause failures. At least k safety units must function successfully for the robot system success. The robot and other failure rates and the partially failed system repair rates are assumed constant and the failed robot-safety system repair time is assumed arbitrarily distributed. Markov and supplementary variable methods were used to perform mathematical analysis of this model. Generalized expressions for state probabilities, system availabilities, reliability, mean time to failure, and variance of time to failure are developed. Plots of some resulting expressions are shown.
An algorithm for Secure formatting of memory
Dhillon Amrit
International Journal of Computer and Distributed System , 2012,
Abstract: Flash memories find wide use in storing data in any application. Data deletion in flash memories involves making the data unreliable on the device. As contents get deleted in the flash memory, time is consumed in deleting the data on the flash permanently. This paper proposes a method to make the contents of the deleted blocks in the flash memory unreliable. The proposed method makes data unreliable by swapping most significant bits into least significant bits in block of data making data recovery impossible
A Generalized Torelli Theorem
Ajneet Dhillon
Mathematics , 2000,
Abstract: Given a smooth projective curve $C$ of genus $g$ over the complex numbers, Torelli's thoerem asserts that the pair $(J(C),W^{g-1})$ determines $C$, where $W^{g-1}$ is an image of the $g-1$st symmetric power of $C$ inside the Jacobian under an Abel-Jacobi map. We show that the theorem holds with $g-1$ replaced by an integer $d$ in the range $1\le d\le g-1$.
On the Cohomology of Moduli of Vector Bundles
Ajneet Dhillon
Mathematics , 2003,
Abstract: We compute some Hodge and Betti numbers of the moduli space of stable rank $r$ degree $d$ vector bundles on a smooth projective curve. We do not assume $r$ and $d$ are coprime. In the process we equip the cohomology of an arbitrary algebraic stack with a functorial mixed Hodge structure. This Hodge structure is computed in the case of the moduli stack of rank $r$, degree $d$ vector bundles on a curve. Our methods also yield a formula for the Poincare polynomial of the moduli stack that is valid over any ground field.
Knowledge Dispersion Index for Measuring Intellectual Capital
Vikram Dhillon
Computer Science , 2011,
Abstract: In this paper we propose a novel index to quantify and measure the flow of information on macro and micro scales. We discuss the implications of this index for knowledge management fields and also as intellectual capital that can thus be utilized by entrepreneurs. We explore different function and human oriented metrics that can be used at micro-scales to process the flow of information. We present a table of about 23 metrics, such as change in IT inventory and percentage of employees with advanced degrees, that can be used at micro scales to wholly quantify knowledge dispersion as intellectual capital. At macro scales we split the economy in an industrial and consumer sector where the flow of information in each determines how fast an economy is going to grow and how overall an economy will perform given the aggregate demand. Lastly, we propose a model for knowledge dispersion based on graph theory and show how corrections in the flow become self-evident. Through the principals of flow conservation and capacity constrains we also speculate how this flow might seeks some equilibrium and exhibit self-correction codes. This proposed model allows us to account for perturbations in form of local noise, evolution of networks, provide robustness against local damage from lower nodes, and help determine the underlying classification into network super-families.
Modeling Instantaneous Changes In Natural Scenes
Vikram Dhillon
Computer Science , 2010,
Abstract: This project aims to create 3d model of the natural world and model changes in it instantaneously. A framework for modeling instantaneous changes natural scenes in real time using Lagrangian Particle Framework and a fluid-particle grid approach is presented. This project is presented in the form of a proof-based system where we show that the design is very much possible but currently we only have selective scripts that accomplish the given job, a complete software however is still under work. This research can be divided into 3 distinct sections: the first one discusses a multi-camera rig that can measure ego-motion accurately up to 88%, how this device becomes the backbone of our framework, and some improvements devised to optimize a know framework for depth maps and 3d structure estimation from a single still image called make3d. The second part discusses the fluid-particle framework to model natural scenes, presents some algorithms that we are using to accomplish this task and we show how an application of our framework can extend make3d to model natural scenes in real time. This part of the research constructs a bridge between computer vision and computer graphics so that now ideas, answers and intuitions that arose in the domain of computer graphics can now be applied to computer vision and natural modeling. The final part of this research improves upon what might become the first general purpose vision system using deep belief architectures and provides another framework to improve the lower bound on training images for boosting by using a variation of Restricted Boltzmann machines (RBM). We also discuss other applications that might arise from our work in these areas.
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