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Search Results: 1 - 10 of 582 matches for " Babacar Diao "
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Semen Abnormality Patterns and Parameters in Male Partners of Infertile Couples in Dakar (Senegal)  [PDF]
Mama Sy Diallo, Abdoulaye Séga Diallo, Pyrrhus Fotso, Yoro Diallo, Babacar Diao, Oumar Faye
Open Journal of Urology (OJU) , 2015, DOI: 10.4236/oju.2015.59024
Abstract: Introduction: Inter individual variation for semen on analysis is well known. Therefore, Semen profile is not the same in individuals from different geographic locations, environments, ways of life, and populations. It is important for a laboratory to have an idea of the semen profile of its population, especially for those who present with infertility. The aim of this study was to draw the pattern of semen abnormalities in male partner of infertile couple in Dakar, Senegal. Materials and Methods: A retrospective study of all the semen samples of male partners of infertile couples submitted for analysis in the laboratory of Cytogenetic and Reproductive Biology of Dakar at the University Teaching hospital from January 2013 to June 2014. Results: A total of 262 male semen analyses were reported. Analysis was performed according to WHO, 2010 manual for examination of human semen. Our study reveals that 80.9% of men in infertile couples present an abnormality in sperm pattern. The main one is oligo-astheno-terato-necrozoospermia (20.2%), followed by azoospermia, (14.1%), astheno-necrospermia (10.3%) and astheno-terato-necro-zoospermia (10.3%). Leucocytospermia was found in 57.8%. Teratozoospermia (80.9%) was the most associated abnormality, followed by necrozoospermia (76.2%). Low sperm count under 5 million per ml concerned 27.7% of the patients, and 11.2% patients had low ejaculate volume. Nearly 42.1% of the male partners are potential candidates for Assisted Reproductive Technology for male infertility. Conclusion: The high rate of semen abnormality in patients of infertile couples and consequently the high rate of potential candidates to Assisted Reproductive Technology for male infertility are important reasons for taking into account rigorously the male subject if we want to improve fertility rate in our context. The pattern of the specific abnormalities found is precious clues to guide management of these patients.
Increased DNA Fragmentation in Patients with Infertility in Dakar (Senegal)  [PDF]
Mama Sy Diallo, Oumar Faye, Abdoulaye Séga Diallo, Yoro Diallo, Babacar Diao
Advances in Reproductive Sciences (ARSci) , 2015, DOI: 10.4236/arsci.2015.34012
Abstract: The presence of DNA fragmentation in semen is associated with poor results in ART (Assisted Re-productive Technology). This has led to the introduction of sperm DNA integrity testing in the clinical assessment of male infertility. The TUNEL assay is one of the most commonly used tests to measure DNA fragmentation in research studies, but it is now being optimized for routine clinical use. So, the objectives of our study were to install the TUNEL assay in our laboratory and to use it to assess the degree of DNA fragmentation in our patients dealing with couple infertility. Forty seven (47) and 25 samples from patients followed up for infertility and known fertile men were analyzed between August 2013 and July 2015 respectively. The sperm samples were evaluated according to the World Health Organization Guidelines. Sperm DNA damage was assessed by the TUNEL assay, with a standardized protocol that we adapted for reading using fluorescence microscopy instead of flow cytometry. The Sperm DNA Fragmentation Index was significantly higher in patients with infertility compared to the controls (22.2% ± 5.6% vs. 16.7% ± 0.7%) with a p < 0.05. This Index was also high in patients with varicocele compared to the control group (22.8% ± 9.2 vs. 16.7% ± 0.7%) (p < 0.01). After establishing the ROC curve (Receiver Operating Characteristics curve), we found a 15% threshold of DNA fragmentation, separating the patients with infertility from the control group. In our study, a 15% threshold positivity of DNA fragmentation using the TUNEL assay was highly associated with infertility. The results indicate that high level DNA fragmentation is associated with infertility.
Congenital Urethral Diverticulum in Male Subject: Report of Three Cases  [PDF]
Yaya Sow, Babacar Sine, Ibrahima Dara Diamé, Ndéye Aissatou Bagayogo, Amath Thiam, Denis Barboza, Alioune Sarr, Cyrille Zé Ondo, Boubacar Fall, Babacar Diao
Open Journal of Urology (OJU) , 2018, DOI: 10.4236/oju.2018.82005
Abstract: Introduction: The urethral diverticulum or urethrocele corresponds to a saccular dilation of a portion of the urethral wall. Our objective was to report the clinical aspects, investigations and therapeutic aspects of three cases of congenital urethrocele. Observations: They were three male patients aged 11, 20 and 42 years, two of whom had consulted for terminal dribbling. The diagnosis of urethrocele was made for all patients with retrograde and voiding cystouretrography. Treatment consisted of resection of the urethrocele followed by urethroplasty for both cases. Conclusion: Diagnostic of congenital urethrocele must always be assessed when there is a persistent terminal dribbling, and systematically ask for a retrograde and voiding cystourethrography to confirm it.
The Radial Nerve Entrapment in Pediatric Extension-Type Supracondylar Humeral Fractures. About Two Cases Reports  [PDF]
Amadou N. Kassé, Malick Diallo, Souleymane Diao, Mohamed Tall, Babacar Thiam, Jean Claude F. Sané, Mouhamadou H. Sy
Open Journal of Orthopedics (OJO) , 2016, DOI: 10.4236/ojo.2016.63008
Abstract: Radial nerve injuries in displaced extension-type supracondylar humeral fractures in children are well known. Entrapment in fracture of radial nerve is uncommon and rarely evocated in literature. We report two similar cases in the mechanism of injury, the clinical findings and the treatment and propose therapeutic guidelines.
Varicocele and DNA Fragmentation in Senegalese Infertile Males—A Study of 95 Cases  [PDF]
Mama Sy Diallo, Oumar Faye, Yoro Diallo, Rokhaya Ndiaye Diallo, Jean Pascal Demba Diop, Abdoulaye Séga Diallo, Babacar Diao
Advances in Reproductive Sciences (ARSci) , 2017, DOI: 10.4236/arsci.2017.53006
Abstract: Varicocele is the first etiology of infertility in men worldwide and affects almost half of the men dealing with infertility in Senegal. Varicocele is associated with a high rate of sperm DNA fragmentation so this test is being more and more recommended especially when patients have to benefit from an ART (Assisted Reproductive Technology) procedure. The aim of our study was to assess if our patients with varicocele are concerned by higher DNA fragmentation rate in spermatozoon. Sperm samples were collected (95 cases of varicocele and 30 controls) and analyzed between January 2013 and June 2016 in a prospective study. Sperm DNA damage, characterized by the rate of DNA fragmentation was evaluated by TUNEL assay using fluorescence microscopy. There was a significant higher percentage of DNA fragmentation in patients with varicocele (p < 0.001), compared to controls. We plan to study a bigger cohort to assess this tendency and study the benefits of surgery in varicocele by evaluating DNA fragmentation after the procedure.
Erectile Dysfunction: Clinical and Epidemiological Aspects in Senegal  [PDF]
Yoro Diallo, Racine Kane, Saint Charles Kouka, Boubacar Fall, Cyrille Ze Ondo, Abdoulaye N’Diaye, Adamson Phiri, Amadou Sékou Soumah, Babacar Diao, Cheickna Sylla
Open Journal of Urology (OJU) , 2015, DOI: 10.4236/oju.2015.59023
Abstract: Introduction: The objective of our study was to analyze the clinical and epidemiologic aspects of erectile dysfunction in subjects with different comorbidities in Senegal. Patients and Methods: This was a retrospective study over a period of 2 years on patients who presented themselves for consultation for erectile dysfunction. The study was carried out in the regions of Dakar and Thies at the Ouakam geriatric center and the Saint Jean of god Hospital of Thies respectively. Results: We enrolled into the study 402 patients with erectile dysfunction. The average age of our patients was 47 ± 5 years. Patients aged more than 60 years were the most. The majority of our patients had less than secondary school level education, 211 in total representing 52.5% of the study population compared to 14.9% having post baccalaureate level. A large number of these patients had professional activities (53.3%), followed by retirees (29.6%). Polygamous patients were more in number (51.5%). In our study sample, we registered 120 active smokers (29.9%). A hundred and ten of our patients were sedentary for periods of 5 months to 22 years. The average length of time before seeking help for erectile dysfunction in our patients was 2.8 years. Severe erectile dysfunction was predominant in the smoking group (54.2%) compared to (9.9%) in the non-smoking group. We found a large proportion of severe and moderate erectile dysfunction (66.3%) and (31.7%) respectively in diabetic than non-diabetic patients. Severe erectile dysfunction was more in hypertensive and diabetics. Severe erectile dysfunction was more present in hypertensive plus smokers (83.9%) than in non-smoking hypertensive patients (68.6%). Severe ED was found more in hypertension and diabetic subjects. Conclusion: Erectile dysfunction is most frequently related on one side to socio-environmental factors, and to co-existing comorbidities on the other side.
Cardiac MRI: Luxury or Necessity, beyond the Electrocardiogram and Biology in the Management of Acute Coronary Syndrome in Young Patients? About 2 Cases Reports in Sub-Saharan Environment  [PDF]
Simon Antoine Sarr, Kana Babaka, Fatou Aw, Malick Bodian, Joseph Mingou, Mouhamadou Bamba Ndiaye, Mor Beye, Amalia Owona, Babacar Mbengue, Adama Kane, Maboury Diao, Serigne Abdou Ba
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.82010
Abstract: Introduction: Precordial pain is a common reason for admission in cardiology, and has many causes. Acute myocarditis in its pseudo-infarctoid form is sometimes difficult to differentiate from myocardial infarction. Cardiac magnetic resonance imaging (MRI) helps to differentiate these two disease entities. We report the respective cases of two young patients, one presenting with myocarditis whilst the other with myocardial infarction. Case Report: We present the cases of two patients. The first who had a recent history of febrile syndrome is a 23-year-old who stopped smoking 3 months prior to presentation whilst the second is a 22-year-old professional footballer with a history of stress with no other cardiovascular risk factors. They were respectively admitted in our emergency department for a constrictive, intense chest pain. Physical examination was normal. The chest pain in both patients was associated with elevated cardiac markers, primary repolarisation abnormalities on ECG, wall motion abnormalities as well as left ventricular systolic dysfunction on transthoracic echocardiography. Coronary angiograms were normal in both patients. In the first patient, MRI concluded with an acute myocarditis with apical akinesia extending to the anterior wall, a T2 hypersignal indicative of myocardial edema, and uptake of a nodular heterogeneous contrast without affecting the sub-endocardial layers on the late enhancement sequences. In the second patient, MRI showed an appearance consistent with acute extensive infarction in the antero-apical region with severe hypokinesia and late quasi-transmural enhancement, impairment of the anterior papillary muscle of the mitral valve and a reduced left ventricular ejection fraction at 33%. In addition to analgesics, the first patient was treated with perindopril and bisoprolol, and the second patient received antithrombotic and anticoagulant treatment. There was clinical improvement in both patients. Conclusion: Cardiac MRI is a useful diagnostic tool for the precise diagnosis of precordial pain with elevated cardiac enzymes, especially in young patients.
Threatened Aortic Injury by Thoracic Pedicle Screw: A Case Report  [PDF]
Amadou Ndiassé Kassé, Souleymane Diao, Magatte Gaye, Jean Claude Sané, Jean Marie Vianey Hope, Karim Hemmam, Babacar Thiam, Pape Adama Dieng, Mouhamadou Habib Sy
Open Journal of Orthopedics (OJO) , 2018, DOI: 10.4236/ojo.2018.82007
Abstract: Iatrogenic vascular injury during posterior spinal surgery is a rare but potentially serious complication with treatment challenges. We report the case of threatened aortic injury by pedicle screw impingement during posterior fixation of thoracic spine T7 - T8 fracture dislocation. The removal of the conflicting screws was done posteriorly after a visual control of the absence of adventitious break-in by a thoracotomy.
Characteristics of the Heart of School-Age Children in a Schistosomiasis Endemic Area in Senegal  [PDF]
Simon Antoine Sarr, Roger Camara, Fassi-Fehri Hicham, Cheikh-Binetou Fall, Ibrahima Sory2 Sylla, Fatou Aw, Malick Bodian, Mouhammadou Bamba Ndiaye, Alassane Mbaye, Adama Kane, Babacar Faye, Maboury Diao, Abdoul Kane, Serigne Abdou Ba
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.89043
Abstract: Introduction: In Senegal, surveys have revealed areas of high endemicity of?Schistosomiasis including the town of Richard Toll. We undertook this study?to determine the echocardiocardiographic characteristics of school-agechildren in endemic bilharziasis. Methodology: We performed a descriptive cross-sectional study in Richard Toll and Dakar in school-age children. Results: A total of 250 children were included. There was male?predominance, age between 4 and 16 (10 years old ± 2.77). Hematuria was reported in 69.6% of cases in endemic areas. Positive testing for Schistoma hæmatobium was found exclusively in Richard-Toll at 33.5%. The diastolic, systolic, basal and median left ventricle dimensions were larger in Richard Toll’s population compared to Dakar. It was the same for the right chambers dimensions. The average pulmonary systolic arterial pressure was greater in Richard-Toll: 26.38 ± 3.16 mmHg versus 21.82 ± 1.73 mmHg in Dakar (p < 0.001). There was a correletion between pulmonary systolic artérial pressure and presence of hematuria, anemia and parasitological positivity. Conclusion: The heart of the school-aged child in endemic area is characterized by larger cavitary dimensions.
Application of the p-Median Problem in School Allocation  [PDF]
Fagueye Ndiaye, Babacar Mbaye Ndiaye, Idrissa Ly
American Journal of Operations Research (AJOR) , 2012, DOI: 10.4236/ajor.2012.22030
Abstract: This paper focus on solving the problem of optimizing students’ orientation. After four years spent in secondary school, pupils take exams and are assigned to the high school. The main difficulty of Education Department Inspection (EDI) of Dakar lies in the allocation of pupils in the suburbs. In this paper we propose an allocation model using the p-median problem. The model takes into account the distance of the standards imposed by international organizations between pupil’s home and school. The p-median problem is a location-allocation problem that takes into account the average (total) distance between demand points (pupil’s home) and facility (pupil’s school). The p-median problem is used to determine the best location to place a limited number of schools. The model has been enhanced and applied to a wide range of school location problems in suburbs. After collecting necessary numerical data to each EDI, a formulation is presented and computational results are carried out.
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