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Search Results: 1 - 10 of 327381 matches for " B.L.;Calil-Elias "
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Pulsed ultrasound therapy accelerates the recovery of skeletal muscle damage induced by Bothrops jararacussu venom
Saturnino-Oliveira, J.;Tomaz, M.A.;Fonseca, T.F.;Gaban, G.A.;Monteiro-Machado, M.;Strauch, M.A.;Cons, B.L.;Calil-Elias, S.;Martinez, A.M.B.;Melo, P.A.;
Brazilian Journal of Medical and Biological Research , 2012, DOI: 10.1590/S0100-879X2012007500033
Abstract: we studied the effect of pulsed ultrasound therapy (ust) and antibothropic polyvalent antivenom (pav) on the regeneration of mouse extensor digitorum longus muscle following damage by bothrops jararacussu venom. animals (swiss male and female mice weighing 25.0 ± 5.0 g; 5 animals per group) received a perimuscular injection of venom (1 mg/kg) and treatment with ust was started 1 h later (1 min/day, 3 mhz, 0.3 w/cm2, pulsed mode). three and 28 days after injection, muscles were dissected and processed for light microscopy. the venom caused complete degeneration of muscle fibers. ust alone and combined with pav (1.0 ml/kg) partially protected these fibers, whereas muscles receiving no treatment showed disorganized fascicules and fibers with reduced diameter. treatment with ust and pav decreased the effects of the venom on creatine kinase content and motor activity (approximately 75 and 48%, respectively). sonication of the venom solution immediately before application decreased the in vivo and ex vivo myotoxic activities (approximately 60 and 50%, respectively). the present data show that ust counteracts some effects of b. jararacussu venom, causing structural and functional improvement of the regenerated muscle after venom injury.
Effect of perimuscular injection of Bothrops jararacussu venom on plasma creatine kinase levels in mice: influence of dose and volume
Calil-Elias, S.;Thattassery, E.;Martinez, A.M.B.;Melo, P.A.;
Brazilian Journal of Medical and Biological Research , 2002, DOI: 10.1590/S0100-879X2002001000018
Abstract: the effect of dose and volume of a perimuscular injection of bothrops jararacussu venom on myonecrosis of skeletal muscle was studied in mice. an increase of the venom dose (0.25 to 2.0 μg/g) at a given volume (50 μl) resulted in an increase in plasma creatine kinase (ck) levels 2 h after injection. plasma ck activity increased from the basal level of 129.27 ± 11.83 (n = 20) to 2392.80 ± 709.43 iu/l (n = 4) for the 1.0 μg/g dose. histological analysis of extensor digitorum longus muscle 4 h after injection showed lesion of peripheral muscle fibers, disorganization of the bundles or the complete degeneration of muscle fibers. these lesions were more extensive when higher doses were injected. furthermore, an increase in volume (12.5 to 100 μl) by dilution of a given dose (0.5 μg/g) also increased plasma ck levels from 482.31 ± 122.79 to 919.07 ± 133.33 iu/l (n = 4), respectively. these results indicate that care should be taken to standardize volumes and sites of venom injections.
Effect of perimuscular injection of Bothrops jararacussu venom on plasma creatine kinase levels in mice: influence of dose and volume
Calil-Elias S.,Thattassery E.,Martinez A.M.B.,Melo P.A.
Brazilian Journal of Medical and Biological Research , 2002,
Abstract: The effect of dose and volume of a perimuscular injection of Bothrops jararacussu venom on myonecrosis of skeletal muscle was studied in mice. An increase of the venom dose (0.25 to 2.0 μg/g) at a given volume (50 μl) resulted in an increase in plasma creatine kinase (CK) levels 2 h after injection. Plasma CK activity increased from the basal level of 129.27 ± 11.83 (N = 20) to 2392.80 ± 709.43 IU/l (N = 4) for the 1.0 μg/g dose. Histological analysis of extensor digitorum longus muscle 4 h after injection showed lesion of peripheral muscle fibers, disorganization of the bundles or the complete degeneration of muscle fibers. These lesions were more extensive when higher doses were injected. Furthermore, an increase in volume (12.5 to 100 μl) by dilution of a given dose (0.5 μg/g) also increased plasma CK levels from 482.31 ± 122.79 to 919.07 ± 133.33 IU/l (N = 4), respectively. These results indicate that care should be taken to standardize volumes and sites of venom injections.
A note on the re-introduction of grey rhebuck pelea capreolus to the Addo Elephant National Park
B.L. Penzhorn
Koedoe : African Protected Area Conservation and Science , 1977, DOI: 10.4102/koedoe.v20i1.954
Abstract: It is the policy of the National Parks Board to attempt to approximate as closely as possible the original wildlife spectrum in every national park wherever practical. Large scale re-introductions of ungulates have taken place, but in most cases there was no accurate documentation of the numbers, sex and sometimes even of the source of the re-introduced animals.
An old reference to 'Hartebeest in the Transvaal Lowveld
B.L. Penzhorn
Koedoe : African Protected Area Conservation and Science , 1985, DOI: 10.4102/koedoe.v28i1.536
Abstract: Dr. Percy Rendall FZS, who visited the Transvaal Lowveld during 1893 and 1894, made the following statement in a field-note on the antelopes which he encountered in the region: THE HARTEBEESTE. Bubalis caama. Zulu: Indhluzela There are a few of these antelopes on the banks of the Krokodil River, opposite Hector's Spruit, and also in the East Lydenburg District of the Transvaal and in South Gazaland.' (Rendall 1895).
Toevoegings tot die blomplantlys van die Bergkwagga Nasionale Park
B.L. Penzhorn
Koedoe : African Protected Area Conservation and Science , 1977, DOI: 10.4102/koedoe.v20i1.956
Abstract: Additions to the check list of flowering plants of the Mountain Zebra National Park. Thirteen additional flowering plant species are reported from the Mountain Zebra National Park, increasing the total reported to 371 species.
Further bird records from the Bontebokand Mountain Zebra National Parks
B.L. Penzhorn
Koedoe : African Protected Area Conservation and Science , 1977, DOI: 10.4102/koedoe.v20i1.957
Abstract: The avifauna of this Park is well-known. Shortly after the Park was relocated to Swellendam in 1960, a preliminary list of the birds of the Park was published (Winterbottom 1962a). This was soon followed by a comprehensive check list (Winterbottom 1967a) and a report on bird densities in the Coastal Renosterbosveld of the Park (Winterbottom 1968a). Six further bird species, five of which have been reported in The Ostrich, are documented here, increasing to 150 the total number of species recorded in the Park. The numbers denote those used in Roberts birds of South Africa (McLachlan and Liversidge 1970) and the nomenclature follows the Check list of the birds of South Africa (S.A.O.S. List Committee 1969).
Mammals
B.L. Penzhorn
Koedoe : African Protected Area Conservation and Science , 1988, DOI: 10.4102/koedoe.v31i1.480
Abstract: At last! A book that tells visitors to the Kruger National Park much more than just gestation period and record horn length of the larger mammals.
Dr. K.C. Mehta and Manoranjan Mitra Award (2009) - B.L. PUTTOO*
B.L. PUTTOO*
Indian Phytopathology , 2011,
Abstract:
Onderstepoort 1908 - 2008, D.W. Verwoerd and R.D. Bigalke (Eds.) : book review
B.L. Penzhorn
Journal of the South African Veterinary Association , 2012, DOI: 10.4102/jsava.v80i2.185
Abstract: October 2008 saw the commemoration of the centenary of the inauguration of the first building on the Onderstepoort campus. This building was declared a national monument in 1983. The roots of the Onderstepoort Veterinary Institute actually go back further, to 1896, when the rinderpest pandemic sweeping down the African continent prompted the government of the then Zuid-Afrikaansche Republiek to establish a 'disinfection station' at Daspoort, on the outskirts of Pretoria, under the supervision of Arnold Theiler. The activities of that rather basic laboratory were transferred in October 1908 to the state-of-the-art building that had been erected on the farm 'De Onderstepoort', north of Pretoria. The name Onderstepoort has since become synonymous with veterinary research and education, not only in South Africa, but also far beyond its borders.
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