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Search Results: 1 - 10 of 554199 matches for " B. A. Olofinbiyi "
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Interaction of Glucose/Sucrose Binding Lectin Isolated from Nigeria Wild Bean with E. coli and S. aureus  [PDF]
O. A. Awoyinka, J. O. Awe, O. A. Omosebi, O. Osukoya, F. C. Oladele, B. A. Olofinbiyi, M. F. Asaolu
Food and Nutrition Sciences (FNS) , 2017, DOI: 10.4236/fns.2017.812080
Lectin purified from wild underutilized local bean—Otili, Feregede, Pakalai was comparatively characterized and further evaluated for interaction with gastrointestinal bacteria—Esherichia coli and Staphylococcus aureus. The purified lectin in all the bean samples showed to be glucose and sucrose binding. The hemagglutinating activity, was non selective to type of blood group (A, B, AB and O). Anti-bacteria interaction with Escherichia coli showed clear zone of inhibition of about 1.5 ± 0.5 mm with lectin from Feregede and Otili while there was slight agglutination with lectin from Pakala. Staphylococcus aureus sensitivity to the lectin extracted from Otili with clear zone of inhibition of 2.0 ± 0.5 mm was also found in the control chloramphenicol. However there was pronounced agglutination with lectin from Feregede and Pakala with Staphylococcus auereus. This may be a clear indication that lectin from local underutilized wild bean understudy will agglutinate and interact with a gram positive bacteria more than gram negative bacteria.
Serum Magnesium Levels in Healthy Pregnant and Pre-Eclamptic Patients
—A Cross-Section Study

D. A. Adekanle, O. T. Adeyemo, A. A. Adeniyi, R. A. Okere, A. K. Jimoh, I. O. Adebara, A. Bakare, A. S. Atiba, A. Adelekan, B. A. Olofinbiyi
Open Journal of Obstetrics and Gynecology (OJOG) , 2014, DOI: 10.4236/ojog.2014.49080

Background: Pre-eclampsia complicates 2% - 8% of pregnancies. Various efforts have been put forward for its prevention and treatment. Magnesium sulphate is presently the recommended drug for the prevention and treatment of eclampsia and severe pre-eclampsia. Objectives: The study aimed to compare the serum magnesium in a healthy pregnant women and pre-eclamptic women. It determined demographic characteristic of the study population and recommended the prophylactic usage of magnesium sulphate in pregnancy in our environment. Method: This was a prospective case control study comparing the serum magnesium levels in pre-eclampsia and normal pregnancy tertiary hospitals. The women who satisfied the inclusion criteria were recruited in the two groups (seventy five in the healthy pregnant women and seventy five in the pre-eclamptic women). The blood samples were collected and analysed for the serum magnesium and urine sample for urinalysis. Result: Total of 150 patients comprises 75 normal pregnant women and 75 cases of pre-eclampsia. The mean serum magnesium in the normal pregnant women was 0.73 (±0.14) mmol/L while in preeclampsia the level was 0.58 (±0.17) mmol/L. This is statistically significant (t = 6.120, p = 0.000). There was significance difference in the mean age of patients with pre-eclampsia and normal pregnancy. The mean parity in the pre-eclampsia was 0.80 and in the normal pregnancy was 1.4 and was statistically significant (t = 3.40, p value < 0.001). The mean gestational age of the pre-eclamptic was 36.5 weeks while it was 28.7 weeks in the normal pregnant women (t = 10.80, p = 0.000). Conclusion: The findings in this research work revealed that the pre-eclamptic women have lower serum magnesium level compared to the normal pregnant women, and it may therefore be interesting to do a larger multicenter study with possibility of developing a marker for this disease of theories.

Comparative Effects of Selected Underutilized Wild Beans on Plasma Lipid Profile and Liver Function of Rats Fed with High Fats Diet  [PDF]
O. A. Awoyinka, T. R. Omodara, F. C. Oladele, D. D. Ajayi, H. A. Babalola, B. A. Olofinbiyi, G. S. Adeleye, E. O. Odesanmi
Food and Nutrition Sciences (FNS) , 2019, DOI: 10.4236/fns.2019.104034
Abstract: Dietary fiber content of beans is known to be responsible in the management of metabolic syndrome by delaying the degree of glucose as fuels, changing fat utilization, and controlling appetite through increased satiety, thus lowering the risk of cardiovascular diseases. Hence some selected varieties of underutilized wild beans were evaluated to study their anti-lipidemic effects. Prior to this, attempts were made to ferment the non-digestible fractions of the beans with fermentable micro-organism and the respective gut metabolites were determined. Lipid profile result carried out in the blood showed high density lipoprotein to be significantly (p ≤ 0.05) high in Pakala group with a value of 2.2 ± 0.02 compared to other groups. While for low density lipoprotein (LDL); rats with Otili in their diet had the highest LDL with a value of 0.45 ± 0.01. However, the group of rats fed with Feregede had the least cholesterol level compared to other groups of rats fed with respective wild beans and the negative control group. Otili had the highest ALP with value of 89 ± 1.0. Otili group also had a significant lower value of both aspartate amino transferase and alanine amino transferase. The biochemical indices reported in this study vary from one type of wild bean to another.
Maternal Plasma Lipid Profile in Women Screened for Gestational Diabetes Mellitus (GDM)  [PDF]
Adeniran Samuel Atiba, Babatunde Ajayi Olofinbiyi, Akindele Rasaq Akintunde, Aduloju Olusola Peter, Ojo Olubunmi Clementinah, Akinlua Ibikunle
Open Journal of Obstetrics and Gynecology (OJOG) , 2017, DOI: 10.4236/ojog.2017.712123
Abstract: Objective: This is to determine the plasma lipid profile status of patients diagnosed with gestational diabetes mellitus. Methodology: Seventy-nine pregnant women between gestational age of 24 and 28 weeks out of which 23 and 16 were diagnosed of having GDM using IADAPSG and WHO guidelines respectively were recruited into the study. Plasma lipid profile was determined among the study groups using standard laboratory techniques. Results: Higher numbers of women were diagnosed with GDM using IASDAPG criteria than when WHO criteria were used. Plasma lipid profile showed no significant difference between women with GDM and Non-GDM irrespective of guidelines used in the diagnosis of GDM. Conclusion: Pregnancy and Gestational Diabetes Mellitus may have influence on lipid metabolism but not likely in the second trimester of pregnancy as observed in our study.
Preoperative pain treatment in acute abdomen in Osogbo, Nigeria: a randomized double-blind placebo-controlled study
Olayide Agodirin, Adetunji Oguntola, Moses Adeoti, Austin Agbakwuru, Kehinde Oluwadiya and Babatunde Olofinbiyi
International Journal of Emergency Medicine , 2013, DOI: 10.1186/1865-1380-6-3
Abstract: The preoperative use of Tramal in acute abdomen improved the experience of pain and did not adversely affect the accuracy of the diagnosis or decision-making.
Prevalence of Antibodies to HIV among Students of Selected Tertiary Schools in Two Southwest States, Nigeria  [PDF]
Gabriel Olugbenga Daramola, Adekemi Olubukunola Oluyege, Helen Abike Edogun, Amos Olakunle Ojerinde, Babatunde Ajayi Olofinbiyi, Ayodele Oluwaseun Ajayi, Olugbenga Omoniyi Ajala, Ogunbola Ogunfolakan, Adebimpe Egbebi, Clement Olawale Esan, Adegboyega Oladele Agbaje
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.58007
Abstract: Young adults generally have been identified as one of the groups of individuals who are particularly at risk of contracting HIV/AIDS and under-graduates constitute a very significant subset among these young adults. Therefore this research was designed to study the specific factors that put undergraduates in ten selected tertiary institutions in southwest Nigeria at risk of contracting HIVAIDS, as well as determine HIV prevalence in these campuses and the viral load of positive subjects. 1000 undergraduates were enrolled in the study, over a period of forty-two months. Baseline retroviral screening was carried out, using a rapid commercial test-kit, DETERMINE®. Confirmatory tests were carried out on positive samples using Enzyme Immuno Assay (EIA) technique. The viral load of the positive samples was determined using Real Time PCR, while the CD4+ count was assayed using Cyflow technique. Four out of the 1000 subjects were confirmed to be positive, thus representing an overall prevalence rate of 0.4%. The CD4 count of the positive subjects were 479/L, 368/L, 420/L and 1063/L. Molecular analysis of the positive subjects’ samples using RT-PCR revealed that the level of viral RNA in two of the subjects’ was too low for detection, while the other two positive subjects had 20 cp/ml and 325 cp/ml of viral RNA in their samples. Analyses of both the negative and positive subjects’ questionnaires were carried out, so as to determine the probable risk-factors that predisposed the positive subjects to infection. Hypotheses tested at p < 0.05 revealed that there was a significant difference in the rate at which the subjects were infected with HIV among the age-groups.
Effect of Mechanical and Chemical Scarification on Germination of Dodder (Cuscuta campestris Yunck.) Seed  [PDF]
A. B. Mustapha, N. A. Gworgwor, B. B. Jakusko
World Journal of Engineering and Technology (WJET) , 2015, DOI: 10.4236/wjet.2015.33B006

Experiments were carried out to evaluate the effect of seed treatment on germination of Cuscuta campestris. This may provide the possible ways to overcome the problem of dormancy in Cuscuta campestris. The experiments were conducted in the Laboratory of Crop Production and Horticulture, Modibbo Adama University of Technology, Yola, Adamawa State, Nigeria, using mechanical scarification and tetraoxosulphate (VI) acid (H2SO4). For the mechanical scarification the treatments were unscarified, scarified using sandpaper and scarified using gravel arranged in a completely randomized design (CRD) and replicated four times. For the tetraoxosulphate (VI) acid (H2SO4) scarification, the treatment of control, 9:1, 7:3, 1:1, 4:6, 3:7, 2:8 and 1:9 H2SO4 were laid out in a Split plot design and replicated three times. The mechanical scarification was not significant (P ≤ 0.05), a rapid increase of germination from day 3 to day 9 was observed, and the highest rate of germination percentage (14% - 22%) obtained on day 9. Tetraoxosulphate (VI) acid treatment of 4:6 concentrations significantly gave the highest C. campestris seeds germination percentage (40.07%) compared with the rest of the treatments, while the time of soaking the seeds in the tetraoxosulphate (VI) acid showed that soaking the seeds for 1 minute significantly gave the highest percentage germination (39.98%) of C. campestris compared with the 3 and 5 minutes soaking treatments. It can be concluded that sulphuric acid of 4:6 concentrations treatments has the potentiality to break dormancy of C. campestris seeds.

Knowledge and Practice of Fundoscopy among Medical Doctors in Port Harcourt, Nigeria  [PDF]
A. A. Onua, B. Fiebai
Open Journal of Ophthalmology (OJOph) , 2016, DOI: 10.4236/ojoph.2016.63023
Abstract: Background: Many clinical entities manifest early characteristic changes in the fundus of the eye. The value of fundoscopy cannot be overemphasized and every medical doctor is expected to be able to use the ophthalmoscope to detect common pathological changes. However, more often than not fundoscopy is seen as an exclusive specialized skill of the ophthalmologist. Aim: The aim of this study was to evaluate knowledge and practice of fundoscopy among the physicians present at the Ordinary General Meeting of the Nigerian Medical Association (Rivers State branch) held in Port Harcourt on 30th June 2014. Methods: A self administered questionnaire about their knowledge and practice of fundoscopy was administered to 125 medical doctors attending the Ordinary General Meeting of the Nigerian Medical Association (Rivers State branch) held in Port Harcourt on 30th June 2014. Questions asked tested the Knowledge and Practice of the physicians on matters related to fundoscopy. Participants’ knowledge and practice were graded as Good for scores of 75% and above, Fair for 50% - 74% score and Poor for scores less than 50%. Respondents’ demographic data, responses and corresponding scores were entered into computer software—Scientific Package for Social Sciences (SPSS) version 20 and subsequently analyzed. Results: The study participants were 125 physicians; 86 males and 39 females (M:F = 2.2:1). Twenty-eight percent of the study participants had good knowledge of fundoscopy while only 15% had good practice. Seventy eight physicians representing 62.4% of the participants could correctly refer patients with the need for fundoscopy to an ophthalmologist, whereas 11 (8.8%) worked in facilities without basic instrument for fundoscopy (ophthalmoscope). Conclusion: Our study demonstrates that knowledge and practice of fundoscopy among medical practitioners in Port Harcourt is poor and far from ideal. Therefore, refresher courses emphasizing the acquisition of the skill in fundoscopy and the provision of ophthalmoscopes in our General Practitioners’ clinics are necessary.
Prevalence, Causes and Management of Neovascular Glaucoma: A 5-Year Review  [PDF]
B. Fiebai, A. A. Onua
Open Journal of Ophthalmology (OJOph) , 2019, DOI: 10.4236/ojoph.2019.91001
Abstract: Purpose: To determine the prevalence, identify the causes and outline the management options available at our center for the treatment of neovascular glaucoma. Setting: The study was carried out in the department of ophthalmology, University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria. Methods: The case records of all patients who were managed in the department of ophthalmology from January 2013 to December 2017 for neovascular glaucoma were retrieved. Data collected included, age, sex, causes of neovascular glaucoma, presenting visual acuity, treatment options and outcomes, systemic and ocular comorbidities. Results were analysed using Statistical Package for Social Sciences (SPSS) 20.0 for Windows statistical software. Results: Thirty-two eyes (32) of twenty-eight patients were studied. The hospital prevalence of neovascular glaucoma was 0.3%. There were 4 cases of bilateral neovascular glaucoma (NVG). Retinal vein occlusion 17 (53%) was the commonest cause of NVG followed by proliferative diabetic retinopathy 13 (41%). Uveitis was seen in only 2 (6%) eyes. The commonest form of intervention used was a combination of medical therapy and anti VEGFs. Fifty percent (50%) of the study population had a lowering of their intraocular pressures within the normal limits post treatment and this was statistically significant (p = 0.000). However, only 10% had an improvement in their visual acuity after treatment. Conclusions: Neovascular glaucoma is a potential blinding condition with challenges in control of intraocular pressures and preservation of vision. Early detection and attention to aetiological factors with timely institution of the appropriate mode of treatment may help in preserving vision.
Total Harmonic Distortion Minimization of Multilevel Converters Using Genetic Algorithms  [PDF]
A. Salami, B. Bayat
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.47139

This paper presents a genetic algorithm (GA) optimization technique to find the optimum switching angles of 11-level inverter with minimum number of dc sources and switches in comparison with the cascade multilevel inverter in order to minimize the total harmonic distortion (THD) of their output voltage waveform. Theoretical and simulation results for an 11-level converter show the efficiency of the proposed algorithm to determine the optimum angles in order to decrease the undesired harmonics and produce very high quality output voltage waveform.

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