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Search Results: 1 - 10 of 144167 matches for " B Laughton "
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Management of children with cerebral palsy
B Laughton
Continuing Medical Education , 2004,
Abstract:
Management of children with cerebral palsy
B Laughton
Continuing Medical Education , 2004,
Abstract:
Neurodevelopmental status of HIV-exposed but uninfected children: A pilot study
P Springer, B Laughton, M Tomlinson, J Harvey, M Esser
South African Journal of Child Health , 2012,
Abstract: Introduction. HIV affects children both directly and indirectly, with evidence of increased infectious mortality and morbidity in the HIV-exposed but uninfected (HEU) infant. There is little published research on neurodevelopmental outcome of HEU infants in Africa. Following the introduction of successful prevention of mother-to-child transmission programmes, it has become important to determine whether differences exist between HEU infants and infants born to HIV-negative mothers in order to guide current management policies of this rapidly growing group of infants. Objectives. To compare the developmental outcome of infants exposed to HIV in utero who remained uninfected (HEU) with that of infants unexposed to HIV in utero (HUU). Methodology. This was a prospective, blinded, hospital-based study. Infants aged between 17 and 19 months were assessed on the Griffiths Mental Developmental Scales (GMDS). Birth history, previous hospitalisation, maternal and infant characteristics, antiretroviral exposure, anthropometric measurements and abnormal clinical findings were documented. Results. Of the original 55 infants enrolled at 2 weeks of age, 37 (17 HEU and 20 HUU) underwent neurological and developmental assessment. There were no significant differences between the groups with regard to the GMDS general quotient or other subscales, apart from the Personal/social subscale, where the HEU group performed significantly more poorly than the HUU participants (p=0.026). This difference is probably a result of cultural differences between the groups, as 76% of HEU and only 15% of HUU participants were of Xhosa origin. Discussion. There was no difference in neurodevelopmental outcome at 18 months between the HEU and HUU groups.
Longitudinal developmental profile of children from low socio-economic circumstances in Cape Town, using the 1996 Griffiths Mental Development Scales
B Laughton, PE Springer, D Grove, S Seedat, M Cornell, M Kidd, SA Madhi, MP Cotton
South African Journal of Child Health , 2010,
Abstract: Background. The Griffiths Mental Development Scales (GMDS) have not been standardised in South African children. Neurodevelopmental scores of infants from deprived environments decline with age, but there is no evidence on how young South African children from such backgrounds perform on serial assessments. Aim. To describe the longitudinal developmental profile of infants from low socio-economic backgrounds at Tygerberg Children’s Hospital by comparing the GMDS scores performed at 10 - 12 months and 20 - 22 months. Methods. Infants born to HIV-uninfected women attending the public service programme were recruited from a vaccine study in Cape Town, South Africa. The GMDS 0 - 2 years and a neurological examination were performed between 10 and 12 months and between 20 and 22 months. Results. Thirty-one infants (14 girls, 17 boys) were assessed. Their mean (standard deviation (SD)) age was 11.6 (0.8) months and 21.0 (0.5) months at the first and second assessments, respectively. The mean (SD) general quotient decreased significantly from 107.3 (11.7) to 95.0 (11.0) (p<0.001). All sub-quotients decreased significantly except for locomotor. The hearing and language sub-quotient was most affected, with a decrease in mean quotients from 113.0 to 93.2 (p<0.001). There was no evidence of intercurrent events to explain the decline. Interpretation. Scores on the GMDS of this group of children from low socio-economic backgrounds were normal at 11 months and, other than locomotor, decreased significantly at 21 months, with language the most affected. Further research is needed to determine the specific reasons for the decline.
Investigating on-line pornography at the University of Johannesburg
P. Laughton,C. Rensleigh
South African Journal of Information Management , 2010, DOI: 10.4102/sajim.v10i2.314
Abstract: The on-line user of today has access to a vast collection of information resources. In addition, the developments in Internet and Web technologies have made it even easier for surfers to anonymously get access to on-line pornography. The purpose of this research was to investigate the extent to which access to on-line pornography at the University of Johannesburg can be managed. For the empirical part of this research 1037 questionnaires were proportionally distributed to and completed by students on all five campuses of the university. The questionnaire consisted of four sections: biographical information; university computer facility usage; university acceptable use policy; and personal experience with university computer facilities. The gender distribution for the sample was almost even, with a total of 49,4% male participants and 50,6% female, with the largest grouping of respondents (61,6%) aged between 19 years and 21 years. Of the respondents, 36,7% indicated that exposure to unsolicited pornography did not bother them. When asked to what extent students should have access to pornography, 60,5% stated 'None' while 32,6% believed that 'Restricted' access should be granted for research purposes and 6,9% believed that students should be granted 'Total' access to pornography. Results from the research will be used to manage access to on-line resources at the University of Johannesburg better.
Investigating on-line pornography at the University of Johannesburg
P. Laughton,C. Rensleigh
South African Journal of Information Management , 2009, DOI: 10.4102/sajim.v9i4.204
Abstract: The on-line user of today has access to a vast collection of information resources. In addition, the developments in Internet and Web technologies have made it even easier for surfers to anonymously get access to on-line pornography. The purpose of this research was to investigate the extent to which access to on-line pornography at the University of Johannesburg can be managed. For the empirical part of this research 1037 questionnaires were proportionally distributed to and completed by students on all five campuses of the university. The questionnaire consisted of four sections: biographical information; university computer facility usage; university acceptable use policy; and personal experience with university computer facilities. The gender distribution for the sample was almost even, with total of 49,4% male participants and 50,6% female, with the largest grouping of respondents (61,6%) aged between 19 years and 21 years. Of the respondents, 36,7% indicated that exposure to unsolicited pornography did not bother them. When asked to what extent students should have access to pornography, 60,5% stated 'None' while 32,6% believed that 'Restricted' access should be granted for research purposes and 6,9% believed that students should be granted 'Total' access to pornography. Results from the research will be used to manage access to on-line resources at the University of Johannesburg better.
Hierarchical analysis of acceptable use policies
P. A. Laughton
South African Journal of Information Management , 2010, DOI: 10.4102/sajim.v10i4.330
Abstract: Acceptable use policies (AUPs) are vital tools for organizations to protect themselves and their employees from misuse of computer facilities provided. A well structured, thorough AUP is essential for any organization. It is impossible for an effective AUP to deal with every clause and remain readable. For this reason, some sections of an AUP carry more weight than others, denoting importance. The methodology used to develop the hierarchical analysis is a literature review, where various sources were consulted. This hierarchical approach to AUP analysis attempts to highlight important sections and clauses dealt with in an AUP. The emphasis of the hierarchal analysis is to prioritize the objectives of an AUP.
Macrodynamics of Disordered and Frustrated Systems
D. Sherrington,A. C. C. Coolen,S. N. Laughton
Physics , 1996,
Abstract: It is shown how the macroscopic non-equilibrium dynamics of a class of systems whose microscopic stochastic dynamics involves disordered and frustrated but range-free interactions can be well described by closed deterministic flow equations; this requires an appropriate choice of order parameters/function and ansatze.
Dynamical Replica Theory for Disordered Spin Systems
A. C. C. Coolen,S. N. Laughton,D. Sherrington
Physics , 1995, DOI: 10.1103/PhysRevB.53.8184
Abstract: We present a new method to solve the dynamics of disordered spin systems on finite time-scales. It involves a closed driven diffusion equation for the joint spin-field distribution, with time-dependent coefficients described by a dynamical replica theory which, in the case of detailed balance, incorporates equilibrium replica theory as a stationary state. The theory is exact in various limits. We apply our theory to both the symmetric- and the non-symmetric Sherrington-Kirkpatrick spin-glass, and show that it describes the (numerical) experiments very well.
Order-Parameter Flow in the SK Spin-Glass II: Inclusion of Microscopic Memory Effects
S. N. Laughton,A. C. C. Coolen,D. Sherrington
Physics , 1995, DOI: 10.1088/0305-4470/29/4/007
Abstract: We develop further a recent dynamical replica theory to describe the dynamics of the Sherrington-Kirkpatrick spin-glass in terms of closed evolution equations for macroscopic order parameters. We show how microscopic memory effects can be included in the formalism through the introduction of a dynamic order parameter function: the joint spin-field distribution. The resulting formalism describes very accurately the relaxation phenomena observed in numerical simulations, including the typical overall slowing down of the flow that was missed by the previous simple two-parameter theory. The advanced dynamical replica theory is either exact or a very good approximation.
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