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Search Results: 1 - 10 of 26534 matches for " Azucena González-Coloma "
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Differential Deterrent Activity of Natural Products Isolated from Allophylus edulis (Sapindaceae)  [PDF]
Martina Díaz, Lucía Castillo, Carmen E. Díaz, Ricardo Guillermo álvarez, Azucena González-Coloma, Carmen Rossini
Advances in Biological Chemistry (ABC) , 2014, DOI: 10.4236/abc.2014.42021
Abstract: The phytochemical study of Uruguayan specimens of Allophylus edulis (Sapindaceae) yielded the isolation of various natural products being some of them reported for the first time in this species. Although most of them are ubiquitous in the plant kingdom, some revealed in this study to have anti insect properties. Two sesquiterpenes (6,7-Epoxicaryophyllene and spathulenol), two phytosterols (sitosterone and sitosterol), a pentacyclic triterpene (lupeol) and a clerodane diterpene were isolated. 6,7-Epoxycaryophyllene, lupeol and sitosterol showed to be deterrent against the aphid Myzus persicae and the coleopteran Epilachna paenulata. Moreover, the crude ethanolic extract of twigs of A. edulis showed to be deterrent against both insect species being some of its fractions also active against another aphid, Rhopalosiphum padi. Various active compounds against different insect models have been isolated from the twigs extract of A. edulis. The results evidenced synergic as well as antagonistic effects in the mixture, summed to differential activity against the insects, a desirable attribute when developing botanical pesticides.
Perfil químico y biológico de aceites esenciales de plantas aromáticas de interés agro-industrial en Castilla-La Mancha (Espa a)
Santana, O.,Cabrera, R.,González-Coloma, A.,Sánchez-Vioque, R.
Grasas y Aceites , 2012, DOI: 10.3989/gya.129611
Abstract: The chemical composition and biological activities of essential oils of Salvia officinalis L., Salvia lavandulifolia Vahl., Lavandula x intermedia Emeric ex Loisel., Lavandula latifolia Medik., Lavandula angustifolia Mill. and Thymus vulgaris L. are presented. The essential oils have been analysed by Gas Chromatography Mass Spectrometry and 61 compounds were identified, 23 of which represented more than 1% of the essential oil. The 1,8 cineole (16-23%) appeared as the main compound of Salvia sp. essential oils. The high content of α-thujone was characteristic in S. officinalis oil. Remarkable concentrations of linalool (30-33%), camphor (5-17%) and linalyl acetate (9-28%) were detected in Lavandula sp. oils while carvacrol (21.6%) and p-cimene (23.7%) were the most abundant compounds in T. vulgaris oil. Biological characterization was based on their bioplaguicide activity. The essential oils studied had strong antifeedant effects against Leptinotarsa decemlineata Say, Spodoptera littoralis Boisd., Myzus persicae Sulzer and Rhopalosiphum padi L., phytotoxic activity against Lactuca sativa L. and Lolium perenne L. and also exhibited high antifungal activity against Fusarium sp. Oils from T. vulgaris and L. latifolia showed the highest levels of bioactivity against all target species. These results provide an added-value to the essential oils of aromatic plants of agro-industrial interest for its potential use in the development of natural agrochemicals. En este trabajo se presenta el estudio químico y biológico de los aceites esenciales de Salvia officinalis L., Salvia lavandulifolia Vahl., Lavandula x intermedia Emeric ex Loisel., Lavandula latifolia Medik., Lavandula angustifolia Mill. y Thymus vulgaris L. El estudio químico por cromatografía de gases acoplada a espectrometría de masas de los aceites esenciales permitió la identificación de 61 compuestos, de los cuales 23 presentaron un porcentaje mayor o igual al 1 %. Los aceites esenciales de Salvia sp. se caracterizaron por presentar un alto contenido de 1,8 cineol (16-23%) y, en el caso específico de S. officinalis, una elevada proporción de α-tuyona (15.7%). En Lavandula sp., los compuestos mayoritarios del aceite fueron linalol (30-33%), alcanfor (5-17%) y acetato de linalilo (9-28%); mientras que en T. vulgaris lo fueron carvacrol (21.6%) y p-cimeno (23.7%). La caracterización biológica, desde el punto de vista de la actividad bioplaguicida, mostró que los aceites ensayados disminuyeron significativamente la alimentación de Leptinotarsa decemlineata Say, Spodoptera littoralis Boisd., Myzus persic
Pyrrolizidine alkaloids of senecio sp from Peru
Artiles, Liliana Ruiz Vásquez and Matías Reina;Coloma, Azucena González;Pérez, Raimundo Cabrera;Mesia, Lastenia Ruiz;
Química Nova , 2011, DOI: 10.1590/S0100-40422011000600015
Abstract: six pyrrolizidine alkaloids (pas) (two saturated macrocyclic, three unsaturated macrocyclic and one unsaturated seco-macrocyclic) were isolated from native peruvian senecio species. the structures of these alkaloids were established by a complete nmr spectroscopic analysis, chemical transformations and comparison of their nmr data with those published for similar alkaloids. three pas were then tested for antifungal activity against fusarium moniliforme, f. (sheldon), f. oxysporum fs. lycopersici (scheldt) and f. solani (mart), no significant activity being observed.
Determinación de proteína C-reactiva en hembras caninas con tumores mamarios benignos y malignos
Crossley,R; Coloma,A; Ríos,C; González,C;
Archivos de medicina veterinaria , 2010, DOI: 10.4067/S0301-732X2010000100014
Abstract: the aim of this study was to determine c-reactive protein levels in dogs with benign and malignant mammary tumors. thirty female dogs, with ages ranging between 6 and 15 years and with no distinction of breed were used for this purpose. the animals were divided into 3 different groups of 10 dogs each: group 1 (control), group 2 (benign mammary tumor) and group 3 (malignant mammary tumor). the neoplasias were classified histologically and c-reactive protein (crp) levels were analyzed using a human turbidimetric immunoassay validated for dogs. group 3 had the highest values (mean: 8.2 mg/l; median: 7.1 mg/l) of c-reactive protein compared with the other groups (p < 0.05). according to a discriminant analysis, a female dog with a mammary tumor and crp values ≥ 8 mg/l has a 61% or greater probability of this tumor being malignant.
Determinación de proteína C-reactiva en hembras caninas con tumores mamarios benignos y malignos Determination of C-reactive protein in female dogs with benign and malignant mammary tumors
R Crossley,A Coloma,C Ríos,C González
Archivos de medicina veterinaria , 2010,
Abstract: El objetivo de este estudio fue determinar los niveles séricos de proteína C-reactiva en caninos con neoplasias mamarias benignas y malignas. Se determinaron concentraciones séricas de proteína C-reactiva en 30 hembras caninas con edades entre 6 y 15 a os, sin discriminación de raza y no esterilizadas. Los animales fueron divididos en tres grupos de 10 individuos cada uno: grupo 1 (control), grupo 2 (neoplasia mamaria benigna) y grupo 3 (neoplasia mamaria maligna). Las neoplasias mamarias fueron clasificadas mediante estudio histopatológico en benignas o malignas. Los niveles séricos de proteína C-reactiva se determinaron a partir de un ensayo inmunoturbidimétrico de uso humano validado en caninos. El grupo 3 fue el que presentó los valores más altos (media 8,2 mg/L, mediana 7,1 mg/L) de proteína C-reactiva con respecto a los otros dos grupos (P < 0,05). De acuerdo con un análisis discriminante, una perra con neoplasia mamaria y valores de CRP ≥ 8 mg/L tiene una probabilidad de un 61% o más de que ésta sea maligna. The aim of this study was to determine C-reactive protein levels in dogs with benign and malignant mammary tumors. Thirty female dogs, with ages ranging between 6 and 15 years and with no distinction of breed were used for this purpose. The animals were divided into 3 different groups of 10 dogs each: Group 1 (control), Group 2 (benign mammary tumor) and Group 3 (malignant mammary tumor). The neoplasias were classified histologically and C-reactive protein (CRP) levels were analyzed using a human turbidimetric immunoassay validated for dogs. Group 3 had the highest values (mean: 8.2 mg/L; median: 7.1 mg/L) of C-reactive protein compared with the other groups (P < 0.05). According to a discriminant analysis, a female dog with a mammary tumor and CRP values ≥ 8 mg/L has a 61% or greater probability of this tumor being malignant.
Control de gestación en inmigrantes
Torre,J. de la; Coll,C.; Coloma,M.; Martín,J. I.; Padron,E.; González González,N. L.;
Anales del Sistema Sanitario de Navarra , 2006, DOI: 10.4321/S1137-66272006000200005
Abstract: the phenomenon of immigration has had an impact on the health care of the population. the immigrant population in spain today represents approximately 8% of the total population. the majority of this population proceeds from countries with low income, and its origin and distribution is diverse. the immigrant population is characterised by its being young and healthy, and with a capacity to adapt to changes, but its social, economic and labour conditions are frequently insecure and favour vulnerability to disease. in spite of the number of immigrants of the male sex being globally higher than that of women, the percentage of immigrants of the female sex is growing. this increase of the female immigrant population has resulted in the appearance of specific health care needs, especially with respect to sexual and reproductive health. to which we must add a substantial increase in pathologies prevalent in the countries of origin, such as anaemia, tuberculosis, malnutrition, haemoglobinopathies, consanguinity, hypocalcaemia, hepatitis b and/or c, sexually transmitted infections, infectious diseases transmitted by arthropods, such as chagas disease and other parasitoses, as well as genital mutilations. the aim of this article is to analyse the factors that make it difficult to control gestation in the immigrant population, as well as to establish guidelines for acting in antenatal care consultations. insistence is placed on health education and prevention during pregnancy, and consideration is given to the appearance of rare diseases related to some of these groups.
Incisiones limbares relajantes y cirugía de la catarata: nuestra experiencia
Coloma-González,I.; González-Herrera,M.; Mengual-Verdú,E.; Hueso-Abancens,J.R.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2007, DOI: 10.4321/S0365-66912007000900007
Abstract: purpose: to evaluate the reduction of pre-existing corneal astigmatism at the time of cataract surgery with limbal relaxing incisions (lris). methods: a prospective study of two groups of patients (treatment and control) with pre-existing astigmatism ≥1d was performed. the 30 patients in the control group had a temporal clear corneal phacoemulsification and the 32 patients of treatment group had combined temporal clear corneal phacoemulsification and lris. holladay analysis was used to assess the efficacy of treatment. an astigmatism distribution and prevalence study in our population is also presented. results: three months after surgery, the mean astigmatism change was -0.55d (-0.75 to -0.35) in the treatment group and 0.04d (-0.3 to 0.3) in the control group (p<.0001). conclusions: lri is a simple, safe and effective method not only for reducing pre-existing astigmatism during cataract surgery but in providing good unaided visual acuity.
Incisiones limbares relajantes y cirugía de la catarata: nuestra experiencia Limbal relaxing incisions and cataract surgery: our experience
I. Coloma-González,M. González-Herrera,E. Mengual-Verdú,J.R. Hueso-Abancens
Archivos de la Sociedad Espa?ola de Oftalmología , 2007,
Abstract: Objetivo: Evaluar la reducción del astigmatismo corneal preexistente en la cirugía de catarata mediante incisiones limbares relajantes (ILRs). Método: Estudio prospectivo de dos grupos de pacientes (tratamiento y control) con astigmatismo prequirúrgico ≥1D. Los 30 pacientes del grupo control fueron sometidos a facoemulsificación por incisión temporal en córnea clara y los 32 pacientes del grupo tratamiento a ILRs junto a facoemulsificación por incisión temporal en córnea clara. Se usó el test de Holladay para valorar la eficacia del tratamiento. Asimismo, presentamos un peque o estudio de la prevalencia y distribución del astigmatismo en nuestra población de trabajo. Resultados: El seguimiento promedio de los 62 pacientes fue de 3 meses, con un cambio astigmático medio a los 3 meses de -0.55D (-0,75 a -0,35) en el grupo tratamiento y de 0.04D (-0,3 a 0,3) en el grupo control (p<,000). Conclusiones: Las ILRs son un método sencillo y efectivo para conseguir reducir el astigmatismo previo durante la cirugía de catarata y con ello la dependencia de gafa. Purpose: To evaluate the reduction of pre-existing corneal astigmatism at the time of cataract surgery with limbal relaxing incisions (LRIs). Methods: A prospective study of two groups of patients (treatment and control) with pre-existing astigmatism ≥1D was performed. The 30 patients in the control group had a temporal clear corneal phacoemulsification and the 32 patients of treatment group had combined temporal clear corneal phacoemulsification and LRIs. Holladay analysis was used to assess the efficacy of treatment. An astigmatism distribution and prevalence study in our population is also presented. Results: Three months after surgery, the mean astigmatism change was -0.55D (-0.75 to -0.35) in the treatment group and 0.04D (-0.3 to 0.3) in the control group (p<.0001). Conclusions: LRI is a simple, safe and effective method not only for reducing pre-existing astigmatism during cataract surgery but in providing good unaided visual acuity.
Avanzando en la gestión y seguridad terapéutica: recuento de comprimidos Advancing in management and therapeutic safety: pill count
Rocío Coto Moreno,ángeles Laviana Fernández,Azucena Pereda González,Ruth álvarez Oviedo
Revista de la Sociedad Espa?ola de Enfermería Nefrológica , 2010,
Abstract:
Efecto de distintos tratamientos de conservación en la actividad antirradicalaria de alcaparras (Capparis spinosa L.) cultivadas en Santiago del Estero, Argentina
Evangelina Adela González,Yanina Soledad Coria Cayupán,Mónica Azucena Nazareno
Revista Venezolana de Ciencia y Tecnología de Alimentos , 2010,
Abstract: Capparis spinosa L. es un arbusto cuyos botones florales, conocidos con el nombre de alcaparras, tienen una amplia aplicación en la gastronomía. Las alcaparras se comercializan en distintas presentaciones de acuerdo a los tratamientos de conservación a los que son sometidas. Se estudiaron posibles variaciones en la actividad antirradicalaria de alcaparras argentinas, como resultado de diferentes métodos de procesamiento en relación con el contenido de flavonoides. Se analizaron botones conservados en vinagre y secados en sal, comparándose los valores obtenidos con los botones frescos y secados en estufa a 55 °C. Paralelamente, con el objetivo de explorar nuevas fuentes de sustancias antioxidantes, se analizaron también las hojas de la planta. Los resultados en cuanto a la determinación de flavonoides indicaron que el contenido total en botones frescos correspondió a 37 mg/g de materia seca mientras que en hojas frescas el valor fue de 23 mg/g de materia seca. El contenido de rutina en ambas muestras correspondió a un 86,5 y 95,6 % del contenido total de flavonoides, para botones y hojas frescas, respectivamente. La actividad antirradicalaria, determinada por el método de decoloración del radical 2,2-difenil-1-picril-hidracilo, mostró correlación con el contenido de flavonoides, siendo mayor para botones frescos con un valor equivalente a 46,7 mg/g de muestra seca. En cuanto al efecto de los tratamientos de conservación sobre los botones florales, se observó que la actividad antirradicalaria decrece en el siguiente orden: botones frescos > conservados en vinagre > secados a 55 °C > secados en sal. La mayor retención de la actividad antirradicalaria se observó en el tratamiento de conservación en vinagre, correspondiendo a un 62 % respecto a la actividad del material fresco. Los resultados indicaron que los botones florales al igual que las hojas son una importante fuente de flavonoides, especialmente rutina, incluso después de los tratamientos aplicados.
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