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Search Results: 1 - 10 of 7941 matches for " Atílio Maximino "
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Abscesso de língua: relato de caso
Carvalho, Thiago Bittencourt Ottoni de;Fernandes, Atílio Maximino;Sanches, Raphael Angelo;
Arquivos Internacionais de Otorrinolaringologia , 2012, DOI: 10.7162/S1809-48722012000100019
Abstract: introduction: the tongue abscesses are rare even being frequently in touch with trauma, bites, and foreign bodies. it occurs because of the immunological features of the saliva and some histological and anatomical characteristics of the tongue. this work has as objective report a case of tongue abscess occurred in our job, and do a literature review. case report: patient of 76 years, male, assisted with complaint of pain when swallowing with progressive evolution for a week, with a significant deterioration over three days. report history of the surgery, for dental implant in the beginning of the period. in the admission during the oral cavity examination was evident bulging of nearly 2x2 cm in the middle third posterior of the right tongue, painful to palpation. was opted the hospitalization of the patient. was required a mri that showed suggestive lesions of abscess in the base of the tongue in the right side. was submitted to a clinical treatment with antibiotic therapy and surgical drainage. the patient recovered uneventfully. discussion: the clinical manifestation from the tongue abscess can be varied. the diagnosis must be done by clinic history, correlating risk factors associated, physical exam and the confirmatory imaging exams. the etiology and the differential diagnosis must be considered depending of the place of the clinical manifestation. the approach must include the permeability of airway, clinical support, and systemic antibiotic therapy and abscess drainage. final considerations: the abscess of the tongue must go in the differential diagnosis of bulging of the tongue being conducted with the antibiotic therapy and surgical drainage in a daily basis.
Mecanismos de a??o dos corticosteróides na polipose rinossinusal
Fernandes, Atílio Maximino;Valera, Fabiana Cardoso Pereira;Anselmo-Lima, Wilma T.;
Revista Brasileira de Otorrinolaringologia , 2008, DOI: 10.1590/S0034-72992008000200020
Abstract: glucocorticoids (gc) are the drugs of choice for the clinical treatment of nasal polyposis, according to the medical literature. its mechanism of action in the regression of clinical symptoms and polyps, however, is not fully understood. the topical and/or systemic use of glucocorticoids lead to variable expression of cytokines, chemokines and lymphokines, as well as changes in cells. it is known that gc suppresses the expression of pro-inflammatory cytokines, chemokines and adhesion molecules such as icam-1 and e-selectin; gc also stimulate the transcription of anti-inflammatory cytokines such as tgf-b. gc suppress pro-fibrotic cytokines related to polyp growth, such as il-11, the basic fibroblast growth factor (b-fgf), and the vascular endotelial growth factor (vegf). the action of gc depends fundamentally on their interaction with receptors (gr); certain subjects have a degree of resistance to its effect, which appears to be related with the presence of a b isoform of gr. gc also act variably on the genes involved in immunoglobulin production, presentation, and antigen processing. aim: we present a review of the literature on the mechanisms of gc action in nasal polyosis. conclusion: understanding the mechanism of action of gc in nasal polyposis will aid in the development of new, more efficient, drugs.
Tongue Abscess: Case Report
Carvalho, Thiago Bittencourt Ottoni de,Fernandes, Atílio Maximino,Sanches, Raphael Angelo
International Archives of Otorhinolaryngology , 2012,
Abstract: Introduction: The tongue abscesses are rare even being frequently in touch with trauma, bites, and foreign bodies. It occurs because of the immunological features of the saliva and some histological and anatomical characteristics of the tongue. This work has as objective report a case of tongue abscess occurred in our job, and do a literature review. Case Report: Patient of 76 years, male, assisted with complaint of pain when swallowing with progressive evolution for a week, with a significant deterioration over three days. Report history of the surgery, for dental implant in the beginning of the period. In the admission during the oral cavity examination was evident bulging of nearly 2x2 cm in the middle third posterior of the right tongue, painful to palpation. Was opted the hospitalization of the patient. Was required a MRI that showed suggestive lesions of abscess in the base of the tongue in the right side. Was submitted to a clinical treatment with antibiotic therapy and surgical drainage. The patient recovered uneventfully. Discussion: The clinical manifestation from the tongue abscess can be varied. The diagnosis must be done by clinic history, correlating risk factors associated, physical exam and the confirmatory imaging exams. The etiology and the differential diagnosis must be considered depending of the place of the clinical manifestation. The approach must include the permeability of airway, clinical support, and systemic antibiotic therapy and abscess drainage. Final Considerations: The abscess of the tongue must go in the differential diagnosis of bulging of the tongue being conducted with the antibiotic therapy and surgical drainage in a daily basis.
Rhino-orbitocerebral mucormycosis associated with cavernous sinus thrombosis: case report
Haber, Daniel Martiniano,Fernandes, Atílio Maximino,Santi Neto, Dalisio De,Schiavetto, Renata Rennó
International Archives of Otorhinolaryngology , 2008,
Abstract: Introduction: Mucormycosis is a rare opportunistic infection caused by Mucorales fungi, and the Rhizopus is the most common one (70% of the cases). It is an acute invasive fungal disease whose form is disseminated, cutaneous, pulmonary, gastrointestinal and rhino-orbitocerebral. The latter is the most common form and its symptoms comprise of unilateral sinusitis, fever and headache. Once established in the orbit the symptoms can be chemosis, diplopia and reduced vision. The infection can spread to the brain via the orbital apex, orbital arteries or via the cribriform plate. Mucormycosis is a medical emergency and the treatment consists of a surgery to an aggressive debridement and in the use of antifungal therapy. Despite the appropriate management, the mortality rate can reach 40% of the cases. One possible intracranial complication of Mucormycosis is the Cavernous Sinus Thrombosis which is a rare and fatal infective disease. The initial symptoms of Cavernous Sinus Thrombosis are headache, retro-orbital pain, periorbital edema, proptosis, diplopia and reduced vision. Case Report: We describe the case of 43-year-old woman with medical history of diabetes mellitus and use of immunosuppressant drugs after kidney transplantation. The patient developed Acute Bacterial Sinusitis and Rhino-orbitocerebral Mucormycosis associated with Cavernous Sinus Thrombosis.
Sinus retrospective analysis of surgeries in a hospital school
Carvalho, Thiago Bittencourt Ottoni de,Conrado, Tiago José,Genaro, Tiago L,Fernandes, Atílio Maximino
International Archives of Otorhinolaryngology , 2010,
Abstract: Introduction: The ENT is a medical specialty that covers 4.4% of all doctors in S o Paulo, with a variety of surgical procedures distributed between pharynx, nose, ear and larynx. Knowing the profile of a reference service in otolaryngology allows for a better organization, scaling the volume of care and surgeries, providing better training to the student and resident physician. Objective: To describe the profile of sinonasal surgery and patients to them in the department of otolaryngology and head and neck surgery at a teaching hospital. Method: We conducted a cohort study of cross-sectional retrospective study with review of 872 charts of patients undergoing surgery Sinus between January 2006 and December 2008. Used questionnaires, seeking sex, age, surgical diagnosis and surgery. Results: Of 872 patients studied, 45.4% were female and 54.6% male, ranging in an age group 40-80 years (mean 29.8 years). The main surgical diagnoses were: nasal septum deviation (n=457), nasal deformity after trauma (n=287), enlarged turbinates (n=153), rhinosinusal polyposis (n=73), chronic sinusitis (n=32). Among the most frequently performed surgical procedures include: septoplasty (n=388), rhinoplasty (n=215), FESS (n=131), intra-turbinal cauterization (n=114), reconstructive rhinoplasty (n=73), turbinectomy (n=43), turbinoplasty (n=55). It is emphasized that patients may have received more than one surgical diagnosis and realized more than one surgery, depending on the alert. Conclusion: We present the volume and diversity of Sinus surgeries performed in our department, contributing to the scarce scientific literature on this type of case.
Análise retrospectiva de cirurgias rinossinusais em um hospital escola
Carvalho, Thiago Bittencourt Ottoni de,Conrado, Tiago José,Genaro, Tiago L,Fernandes, Atílio Maximino
Arquivos Internacionais de Otorrinolaringologia , 2010,
Abstract: Introdu o: A otorrinolaringologia é uma especialidade médica que abrange 4,4% do total de médicos paulistas, tendo uma variedade de procedimentos cirúrgicos distribuídos entre faringe, nariz, ouvido e laringe. O conhecimento do perfil de um servi o de referência em otorrinolaringologia permite a sua melhor organiza o, dimensionamento do volume do atendimento e das cirurgias realizadas, proporcionando uma melhor forma o ao aluno e ao médico residente. Objetivo: Descrever o perfil das cirurgias nasossinusais e dos pacientes submetidos a elas no departamento de otorrinolaringologia e cirurgia de cabe a e pesco o de um hospital escola. Método: Foi realizado estudo de coorte histórico com corte transversal retrospectivo, com revis o de 872 prontuários de pacientes submetidos a cirurgias rinossinusais entre janeiro de 2006 e dezembro de 2008. Utilizado questionário próprio, buscando sexo, idade, diagnóstico cirúrgico e cirurgia realizada. Resultados:Do total de 872 pacientes analisados, 45,4% eram sexo feminino e 54,6% sexo masculino, variando em uma faixa etária 4 a 80 anos (média de 29,8 anos). Os principais diagnósticos cirúrgicos foram: desvio septo nasal(n=457), deformidade nasal pós-trauma (n=287), hipertrofia de conchas nasais (n=153), polipose rinossinusal(n=73), rinossinusite cr nica(n=32). Entre os procedimentos cirúrgicos mais frequentemente realizadas, est o: septoplastia (n=388), rinosseptoplastia (n=215), FESS (n=131), cauteriza o intra-turbinal(n=114), rinoplastia reparadora(n=73), turbinectomia(n=43), turbinoplastia (n=55). Ressalta-se que os pacientes podem ter recebido mais de um diagnóstico cirúrgico e realizado mais de uma cirurgia, dependendo da indica o. Conclus o: Apresenta-se o volume e a diversidade de cirurgias rinossinusais realizadas em nosso servi o, contribuindo com a escassa produ o científica sobre esse tipo de casuística.
Mucormicose rino-órbito-cerebral associada com trombose do seio cavernoso: relato de caso
Haber, Daniel Martiniano,Fernandes, Atílio Maximino,Santi Neto, Dalisio De,Schiavetto, Renata Rennó
Arquivos Internacionais de Otorrinolaringologia , 2008,
Abstract: Introdu o: A Mucormicose é uma infec o oportunista rara causada por fungos da ordem dos Mucorales, sendo o Rhizopus o gênero mais comum (70% dos casos). Esta é uma infec o fúngica invasiva aguda que pode apresentar-se na forma disseminada, cutanea, pulmonar, gastrointestinal e rino-órbito-cerebral (forma mais comum). Nesta última, as queixas mais comuns s o de rinorréia unilateral, febre e cefaléia. Quando há envolvimento orbitário as queixas podem ser de quemose, diplopia e diminui o da acuidade visual. A infec o pode disseminar-se para o Sistema Nervoso Central através do ápice orbitário, da placa cribiforme ou causar trombose em artérias que irrigam o Sistema Nervoso Central. A Mucormicose é uma emergência médica e o tratamento consiste na cirurgia para debridamento agressivo e no uso de antifúngicos sistêmicos. Mesmo com a terapêutica adequada à taxa de mortalidade chega a até 40% dos casos. Uma possível complica o intracraniana da Mucormicose é a Trombose de Seio Cavernoso que é uma infec o rara e com alta taxa de mortalidade. Na Trombose de Seio Cavernoso as queixas iniciais s o de cefaléia, dor retro-orbital, edema periorbitário, proptose, diplopia e diminui o da acuidade visual. Relato do Caso: Nós relatamos o caso de uma paciente com 43 anos de idade com antecedentes de diabetes mellitus e uso drogas imunossupressoras para transplante renal, que desenvolveu quadro de Rinossinusite Bacteriana Aguda e Rinossinusite Fúngica Invasiva Aguda associada à Trombose de Seio Cavernoso.
Evolutionary Changes in the Complexity of the Tectum of Nontetrapods: A Cladistic Approach
Caio Maximino
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0003582
Abstract: Background The tectum is a structure localized in the roof of the midbrain in vertebrates, and is taken to be highly conserved in evolution. The present article assessed three hypotheses concerning the evolution of lamination and citoarchitecture of the tectum of nontetrapod animals: 1) There is a significant degree of phylogenetic inertia in both traits studied (number of cellular layers and number of cell classes in tectum); 2) Both traits are positively correlated accross evolution after correction for phylogeny; and 3) Different developmental pathways should generate different patterns of lamination and cytoarchitecture. Methodology/Principal Findings The hypotheses were tested using analytical-computational tools for phylogenetic hypothesis testing. Both traits presented a considerably large phylogenetic signal and were positively associated. However, no difference was found between two clades classified as per the general developmental pathways of their brains. Conclusions/Significance The evidence amassed points to more variation in the tectum than would be expected by phylogeny in three species from the taxa analysed; this variation is not better explained by differences in the main course of development, as would be predicted by the developmental clade hypothesis. Those findings shed new light on the evolution of an functionally important structure in nontetrapods, the most basal radiations of vertebrates.
Modulation of nociceptive-like behavior in zebrafish (Danio rerio) by environmental stressors
Maximino, Caio;
Psychology & Neuroscience , 2011, DOI: 10.3922/j.psns.2011.1.017
Abstract: zebrafish have been demonstrated to react consistently to noxious chemical stimuli and present reliable phenotypes of stress, fear, and anxiety. in this article, we describe the modulation of nociceptive-like responses of zebrafish to fear-, stress-, and anxiety-eliciting situations. animals were exposed to an alarm substance, confinement stress, or a novel environment before being injected with 1% acetic acid in the tail. the alarm substance and confinement stress reduced the display of erratic movements and tail-beating behavior elicited by acetic acid. the novelty of the environment, in contrast, increased the frequency of tail-beating behavior. the results suggest that descending modulatory control of nociception exists in zebrafish, with apparent fear- and stress-induced analgesia and anxiety-induced hyperalgesia.
Modulation of nociceptive-like behavior in zebrafsh (Danio rerio) by environmental stressors
Caio Maximino
Psychology & Neuroscience , 2011,
Abstract: Zebrafsh have been demonstrated to react consistently to noxious chemical stimuli and present reliable phenotypes of stress, fear, and anxiety. In this article, we describe the modulation of nociceptive-like responses of zebrafsh to fear-, stress-, and anxiety-eliciting situations. Animals were exposed to an alarm substance, confnement stress, or a novel environment before being injected with 1% acetic acid in the tail. The alarm substance and confnement stress reduced the display of erratic movements and tail-beating behavior elicited by acetic acid. The novelty of the environment, in contrast, increased the frequency of tail-beating behavior. The results suggest that descending modulatory control of nociception exists in zebrafsh, with apparent fear- and stress-induced analgesia and anxiety-induced hyperalgesia.
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