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Search Results: 1 - 10 of 140256 matches for " Ashok K. Batra "
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Pyroelectric Properties of PVDF:MWCNT Nanocomposite Film for Uncooled Infrared Detectors  [PDF]
Matthew E. Edwards, Ashok K. Batra, Ashwith K. Chilvery, Padmaja Guggilla, Michael Curley, Mohan D. Aggarwal
Materials Sciences and Applications (MSA) , 2012, DOI: 10.4236/msa.2012.312124
Abstract: Pyroelectric multi-walled carbon nanotubes:polyvinylidene fluoride (PVDF:MWCT) composite films have been fabriccated by the solution casting technique. The pyroelectric and dielectric properties of the composite films were examined for their use in uncooled infrared detectors. The properties measured include: 1) dielectric constants and 2) pyroelec- tric coefficient as a function of temperature. From the foregoing parameters, materials Figures-of-merit, for infrared detection and thermal-vidicons, were calculated. The results indicated Figures-of-merit of composite film were higher than pristine polyvinylidene fluoride films.
Electronic Transport Mechanisms in PVDF/ZnO Nanocomposite Films  [PDF]
Bir B. Bohara, Ashok K. Batra, James R. Currie Jr.
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105707
In this report, we present fundamental DC conduction mechanisms of pol-yvinyl difluoride/nano-zinc oxide (PVDF/ZnO) composite films. Nano-composite films of zinc oxide in the PVDF matrix have been fabricated via a solution casting method. Space charge limited conduction (SCLC) was found to be a prominent conduction mechanism in higher voltage region and Schottky- Richardson mechanism was a possible conduction mechanism in a higher temperature region. DC activation energy for composites was found to decrease with increasing concentration of ZnO nanoparticles and reduced graphene oxide (RGO) with 1.41 eV (9.9 wt%), 1.04 eV (33.33 wt%), and 0.95 eV (33.33 wt% RGO), respectively.
A Versatile Technique for the Fabrication of PEDOT: PSS Films for Organic Solar Cells
Ashwith K. Chilvery,Ashok K. Batra,Padmaja Guggilla,R. B. Lal
Energy Science and Technology , 2012, DOI: 10.3968/j.est.1923847920120402.528
Abstract: Organic solar cells hold the potential of low-cost production as compared to inorganic solar cells, as well as the increase in efficiency. To realize these possibilities, the key is to fabricate most of the functional films in requisite structures via ambient solution-processed techniques. The PEDOT: PSS films, which are commonly used as an anode layer in organic electronic devices, were deposited on large-area ITO glass substrates under optimized conditions. The spin, spray, brush and brush+spray-coating techniques were utilized to examine their suitability in the fabrication of organic solar cells (OSCs). The films were characterized for their morphology, molecular structure, optical and electrical properties and results are compared with the existing data. A smooth and thin films of PEDOT: PSS were obtained by “Spray+Brush” coating method with attractive sheet-conductivity having potential in fabricating OSCs with different architectures. Key words: Organic solar cells; PEDOT: PSS films; Solution-processed techniques
Feedback Reliability Ratio of an Intrusion Detection System  [PDF]
Usha Banerjee, Gaurav Batra, K. V. Arya
Journal of Information Security (JIS) , 2012, DOI: 10.4236/jis.2012.33030
Abstract: The behavior and nature of attacks and threats to computer network systems have been evolving rapidly with the advances in computer security technology. At the same time however, computer criminals and other malicious elements find ways and methods to thwart such protective measures and find techniques of penetrating such secure systems. Therefore adaptability, or the ability to learn and react to a consistently changing threat environment, is a key requirement for modern intrusion detection systems. In this paper we try to develop a novel metric to assess the performance of such intrusion detection systems under the influence of attacks. We propose a new metric called feedback reliability ratio for an intrusion detection system. We further try to modify and use the already available statistical Canberra distance metric and apply it to intrusion detection to quantify the dissimilarity between malicious elements and normal nodes in a network.
Infantile onset of Cockayne syndrome in two siblings
Batra Prerna,Saha Abhijeet,Kumar Ashok
Indian Journal of Dermatology, Venereology and Leprology , 2008,
Syntax score: The fallacies and remedies—A perspective  [PDF]
Pravin K. Goel, Roopali Khanna, Aditya Batra, Sanjeev K. Syal
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.37070
Abstract: The syntax score devised as a tool to grade complexity of coronary artery disease with a view to its suitability for PCI or otherwise on deeper introspection is fraught with some inherent limitations and fallacies largely as a result of the variability in coronary anatomy and the fixed nomenclature of the devised scoring system. We, in this special report, bring out the limitations and fallacies in the same and possible remedies presented as a viewpoint which may be useful to the interventional community at large.
Characteristics of Nanoparticles-Based Chemical Sensors  [PDF]
Jason Stephens, A. K. Batra, James R. Currie
Materials Sciences and Applications (MSA) , 2012, DOI: 10.4236/msa.2012.37063
Abstract: Semiconducting nanoparticle tin oxide-based sensors have been prepared with a pressure load of 4, 6, 8, 10 tons and reinforced with carbon nanofibers (CNF) in SnO2 matrix. The SnO2/CNF sensor’s sensitivity for ethyl alcohol has in-creased by a factor of two, in compared with that of pure SnO2 8-ton pressed sensor with lower response time. These results open the way towards further optimized lower cost CNF nanocomposite sensors as compared with expensive tin oxide/carbon nanotubes sensors.
Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy
Murielle Mimeault, Surinder K Batra
Chinese Medicine , 2011, DOI: 10.1186/1749-8546-6-31
Abstract: The deregulation and sustained activation of multiple tumorigenic pathways are typically implicated in cancer development and progression to locally advanced, aggressive and metastatic stages as well as in treatment resistance and disease relapse [1-5]. Consequently, the use of therapeutic agents acting on different deregulated gene products, alone or in combination therapy, may represent a potentially better strategy than the targeting of one specific oncogenic product to overcome treatment resistance and prevent cancer development and disease recurrence [1-5]. The non-toxic substance curcumin is the major bioactive ingredient extracted from the rhizome of the plant Curcuma longa Linn, also as known as turmeric [6,7]. Curcumin has been used as a dietary supplement as well as a therapeutic agent in Chinese medicine and other Asian medicines for centuries [6,7]. Recently, curcumin, which is a polyphenolic compound, has emerged worldwide as a potent therapeutic substance for treating diverse human diseases. Curcumin displays a wide range of pharmacological properties against various human disorders, such as metabolic and infectious diseases, diabetes, psoriasis, rheumatoid arthritis, atherosclerosis, Parkinson's and Alzheimer's diseases and cancer [6-14].In vitro and in vivo studies have indicated that curcumin induces chemopreventive and chemotherapeutic effects against various types of human cancers. More specifically, curcumin exhibits anticarcinogenic effects on leukemias, lymphomas, multiple myeloma, brain cancer and melanoma as well as skin, cervix, lung, prostate, breast, ovarian, bladder, liver, gastrointestinal tract, pancreatic and colorectal epithelial cancers [2,9,15-36]. Curcumin displays strong anti-inflammatory, antioxidant, anti-aging, chemopreventive, antitumoral, anti-angiogenic, anti-metastatic, radiosensitizing and chemosensitizing effects in cancer cells in a concentration- and cell type-dependent manner (Figures 1 and 2) [2,7,9,10,22,37-39]. Of t
Anti-cancer potential of flavonoids: recent trends and future perspectives
Priya Batra,Anil K. Sharma
3 Biotech , 2013, DOI: 10.1007/s13205-013-0117-5
Abstract: Cancer is a major public health concern in both developed and developing countries. Several plant-derived anti-cancer agents including taxol, vinblastine, vincristine, the campothecin derivatives, topotecan, irinotecan and etoposide are in clinical use all over the world. Other promising anti-cancer agents include flavopiridol, roscovitine, combretastatin A-4, betulinic acid and silvestrol. From this list one can well imagine the predominance of polyphenols, flavonoids and their synthetic analogs in the treatment of ovarian, breast, cervical, pancreatic and prostate cancer. Flavonoids present in human diet comprise many polyphenolic secondary metabolites with broad-spectrum pharmacological activities including their potential role as anti-cancer agents. A positive correlation between flavonoids-rich diet (from vegetables and fruits) and lower risk of colon, prostate and breast cancers lead to a question that whether flavonoids mediate the protective effects as chemopreventive agents or can interact with different genes and proteins to play role in chemotherapy. The current review emphasizes onto the therapeutic potential of flavonoids and their synthetic analogs as anti-cancer agents by providing new insights into the factors, regulation and molecular mechanisms along with their significant protein interactions.
Novel biomarkers and therapeutic targets for optimizing the therapeutic management of melanomas
Murielle Mimeault,Surinder K Batra
World Journal of Clinical Oncology , 2012, DOI: 10.5306/wjco.v3.i3.32
Abstract: Cutaneous malignant melanoma is the most aggressive form of skin cancer with an extremely poor survival rate for the patients diagnosed with locally invasive and metastatic disease states. Intensive research has led in last few years to an improvement of the early detection and curative treatment of primary cutaneous melanomas that are confined to the skin by tumor surgical resection. However, locally advanced and disseminated melanomas are generally resistant to conventional treatments, including ionizing radiation, systemic chemotherapy, immunotherapy and/or adjuvant stem cell-based therapies, and result in the death of patients. The rapid progression of primary melanomas to locally invasive and/or metastatic disease states remains a major obstacle for an early effective diagnosis and a curative therapeutic intervention for melanoma patients. Importantly, recent advances in the melanoma research have led to the identification of different gene products that are often implicated in the malignant transformation of melanocytic cells into melanoma cells, including melanoma stem/progenitor cells, during melanoma initiation and progression to locally advanced and metastatic disease states. The frequent deregulated genes products encompass the oncogenic B-RafV600E and N-RasQ61R mutants, different receptor tyrosine kinases and developmental pathways such as epidermal growth factor receptor (EGFR), stem cell-like factor (SCF) receptor KIT, hedgehog, Wnt/β-catenin, Notch, stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor-4 (CXCR4) and vascular endothelial growth factor (VEGF)/VEGFR receptor. These growth factors can cooperate to activate distinct tumorigenic downstream signaling elements and epithelial-mesenchymal transition (EMT)-associated molecules, including phosphatidylinositol 3’-kinase (PI3K)/Akt/ molecular target of rapamycin (mTOR), nuclear factor-kappaB (NF-κB), macrophage inhibitory cytokine-1 (MIC-1), vimentin, snail and twist. Of therapeutic relevance, these deregulated signal transduction components constitute new potential biomarkers and therapeutic targets of great clinical interest for improving the efficacy of current diagnostic and prognostic methods and management of patients diagnosed with locally advanced, metastatic and/or relapsed melanomas.
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