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Search Results: 1 - 10 of 226899 matches for " Arturo R Palomares "
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Genetic polymorphisms in folate pathway enzymes, DRD4 and GSTM1 are related to temporomandibular disorder
Angel Aneiros-Guerrero, Ana M Lendinez, Arturo R Palomares, Beatriz Perez-Nevot, Lidia Aguado, Alvaro Mayor-Olea, Maximiliano Ruiz-Galdon, Armando Reyes-Engel
BMC Medical Genetics , 2011, DOI: 10.1186/1471-2350-12-75
Abstract: A case-control study was designed to evaluate the impact of genetic polymorphisms above described on TMD. A total of 229 individuals (69% women) were included at the study; 86 were patients with TMD and 143 were healthy control subjects. Subjects underwent to a clinical examination following the guidelines by the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Genotyping of 20 Single Nucleotide Polymorphisms (SNPs), divided in two groups, was performed by multiplex minisequencing preceded by multiplex PCR. Other seven genetic polymorphisms different from SNPs (deletions, insertions, tandem repeat, null genotype) were achieved by a multiplex-PCR. A chi-square test was performed to determine the differences in genotype and allelic frequencies between TMD patients and healthy subjects. To estimate TMD risk, in those polymorphisms that shown significant differences, odds ratio (OR) with a 95% of confidence interval were calculated.Six of the polymorphisms showed statistical associations with TMD. Four of them are related to enzymes of folates metabolism: Allele G of Serine Hydoxymethyltransferase 1 (SHMT1) rs1979277 (OR = 3.99; 95%CI 1.72, 9.25; p = 0.002), allele G of SHMT1 rs638416 (OR = 2.80; 95%CI 1.51, 5.21; p = 0.013), allele T of Methylentetrahydrofolate Dehydrogenase (MTHFD) rs2236225 (OR = 3.09; 95%CI 1.27, 7.50; p = 0.016) and allele A of Methionine Synthase Reductase (MTRR) rs1801394 (OR = 2.35; 95CI 1.10, 5.00; p = 0.037). An inflammatory oxidative stress enzyme, Gluthatione S-Tranferase Mu-1(GSTM1), null allele (OR = 2.21; 95%CI 1.24, 4.36; p = 0.030) and a neurotransmission receptor, Dopamine Receptor D4 (DRD4), long allele of 48 bp-repeat (OR = 3.62; 95%CI 0.76, 17.26; p = 0.161).Some genetic polymorphisms related to folates metabolism, inflammatory oxidative stress, and neurotransmission responses to pain, has been significantly associated to TMD syndromeTemporomandibular joint disorder (TMD) is characterized by a set of symptoms
Human genetic selection on the MTHFR 677C>T polymorphism
álvaro Mayor-Olea, Gonzalo Callejón, Arturo R Palomares, Ana J Jiménez, María Gaitán, Alfonso Rodríguez, Maximiliano Ruiz, Armando Reyes-Engel
BMC Medical Genetics , 2008, DOI: 10.1186/1471-2350-9-104
Abstract: A total of 1305 subjects born in the 20th century were genotyped for the 677C>T polymorphism using allele specific real-time PCR with Taqman? probes. A section of our population (n = 276) born in 1980–1989 was compared with fetal samples (n = 344) from SA of unknown etiology from the same period.An increase in the frequency of the T allele (0.38 vs 0.47; p < 0.001) and of the TT genotype (0.14 vs 0.24; p < 0.001) in subjects born in the last quarter of the century was observed. In the 1980–1989 period, the results show that the frequency of the wild type genotype (CC) is about tenfold lower in the SA samples than in the controls (0.03 vs 0.33; p < 0.001) and that the frequency of the TT genotype increases in the controls (0.19 to 0.27) and in the SA samples (0.20 to 0.33 (p < 0.01)); r = 0.98.Selection in favor of the T allele has been detected. This selection could be due to the increased fetal viability in early stages of embryonic development, as is deduced by the increase of mutants in both living and SA populations.The methylenetetrahydrofolate reductase enzyme (MTHFR) catalyzes a reaction that produces 5-methyltetrahydrofolate (5-methylTHF), the methyl donor for homocysteine in the synthesis of methionine. The 677C>T mutation of the MTHFR gene has been associated with a thermolabile enzyme with decreased activity that may cause an increase in plasma homocysteine concentrations [1] when folate status is poor. This polymorphism is one of the most widely studied clinically relevant polymorphisms in humans, as it is related to cardiovascular disease [2] and neural tube defects (NTD; 601634) [3].A large number of studies have provided a broad overview of the prevalence of the 677C>T polymorphism in different human populations, showing that the distribution of frequencies is diverse [4]. These differences have been also observed between groups of different ages in the same Spanish population (older and younger than 24 years) [5] and in a Swiss population (older and
Análisis de la producción científica de los estudios de traducción en Espa a
Palomares Perraut, R.
Revista Espa?ola de Documentación Científica , 1998,
Abstract: This article studies the literature produced on Translation Studies in Spain between 1960 and 1994. An analytical subject database named TRADES has been created and is used to obtain results regarding quinquennial productivity, productivity of different types of documents, pairs of languages, academic research, and most developed topics in all documents and in journals. The results show the volume of publications on Translation Studies is directly related to the implementation of the Spanish undergraduate degree in Translation. Se estudia la producción bibliográfica de los Estudios de Traducción en Espa a durante el período 1960-1994. A partir de la información documental seleccionada en la base de datos TRADES se analizan las siguientes variables: productividad por quinquenios, productividad por tipología documental, pares de lenguas, investigación (tesis y tesinas), materias y líneas temáticas preferentes de las revistas de traducción. Los resultados aportados muestran una correlación entre el volumen de publicaciones y la implantación de la licenciatura de Traducción e Interpretación.
Nivel de conocimiento que poseen médicos residentes sobre la Norma oficial Mexicana del Expediente Clínico
Rillo,Arturo G; Palomares Pulido,Pablo; Arceo Guzmán,Mario E;
Humanidades M??dicas , 2008,
Abstract: introduction: knowing the mexican regulations for clinical files (nom - 168) has become an important aspect in postgraduate medical formation because an appropriate integration of the clinical file optimizes the doctor-patient relation and is a concrete objective reference for legally medical problems. this investigation is aimed at identifying medical residents' knowledge level of nom - 168. material and methods: an observational, cross-sectional, prospective and descriptive study has been carried out and included 56 residents of general surgery, traumatology, internal medicine, anesthesiology and radiology. a 40-item questionnaire has been applied and included five areas: personal data, clinical file, outpatient file, and notes on hospitalization and other documents. data have been analyzed using kruskal wallis and u-mann-whitney tests. results: in a 0 - 10 scale, the studied population's knowledge level of nom-168 has been of 7.88±0.85 (ic95=7.65;8.11). general surgery and its second - year residency had the highest scores (8.55±0.52; ic95=8.18;8.92 and 8.06±0.84; ic95=7.61;8.50; respectively). general surgery residents have a higher level of knowledge than internal medicine and radiology residents (p<0.05). there has been no clear differences according to the year of residency or any previous knowledge of nom - 168. conclusions: residents involved in the study have an average knowledge of nom - 168. promoting the knowledge of these regulations since the beginning of the career studies has become evidently important.
Nivel de conocimiento que poseen médicos residentes sobre la Norma oficial Mexicana del Expediente Clínico Medical Residents' Level of Knowledge of Mexican Regulations for Clinical Files
Arturo G Rillo,Pablo Palomares Pulido,Mario E Arceo Guzmán
Humanidades M??dicas , 2008,
Abstract: Introducción: El conocimiento de la NOM-168 constituye un aspecto importante en la formación médica de posgrado, pues la integración adecuada del expediente clínico optimiza la relación médico-paciente y es el referente objetivo y concreto ante problemas médico-legales; por lo que el estudio se realizó con el propósito de identificar el nivel de conocimiento que poseen los médicos residentes sobre la NOM-168. Material y métodos: El estudio fue observacional, transversal, prospectivo y descriptivo. Incluyó 56 residentes de Cirugía General, Traumatología, Medicina Interna, Anestesiología y Radiología. Se aplicó un cuestionario de 40 preguntas relacionadas a 5 áreas: generalidades, expediente clínico, expediente en consulta externa, notas médicas en hospitalización y otros documentos. Se utilizaron las pruebas de Kruskal Wallis y U de Mann-Whitney. Resultados: En escala de 0 a 10, el nivel de conocimiento sobre la NOM-168 de la población en estudio fue de 7.88±0.85 (IC95=7.65;8.11). La mayor puntuación se obtuvo en Cirugía General (8.55±0.52; IC95=8.18;8.92) y el segundo a o de residencia (8.06±0.84; IC95=7.61;8.50). Los residentes de Cirugía General poseen un mayor conocimiento que los de Medicina Interna y Radiología (p<0.05). No se identificaron diferencias significativas (p>0.05) en relación al a o de residencia que se cursa o al conocimiento previo de la NOM-168. Discusión: Los médicos residentes participantes en el estudio poseen en promedio un conocimiento regular de la NOM-168 lo que destaca la importancia de promover su difusión desde los estudios de licenciatura. Introduction: Knowing the Mexican Regulations for Clinical Files (NOM - 168) has become an important aspect in postgraduate medical formation because an appropriate integration of the clinical file optimizes the doctor-patient relation and is a concrete objective reference for legally medical problems. This investigation is aimed at identifying medical residents' knowledge level of NOM - 168. Material and methods: An observational, cross-sectional, prospective and descriptive study has been carried out and included 56 residents of General Surgery, Traumatology, Internal Medicine, Anesthesiology and Radiology. A 40-item questionnaire has been applied and included five areas: personal data, clinical file, outpatient file, and notes on hospitalization and other documents. Data have been analyzed using Kruskal Wallis and U-Mann-Whitney tests. Results: In a 0 - 10 scale, the studied population's knowledge level of NOM-168 has been of 7.88±0.85 (IC95=7.65;8.11). General Surgery and its second
La política en la periferia de la modernidad Esbozos para su observación en América Latina
VALLEJOS R,ARTURO;
Cuadernos del Cendes , 2007,
Abstract: this paper proposes to observe latin america from a modern, world-wide society differentiated by functions, with independent and non transparent systems. upon this, we offer a theoretical and methodological delineation illustrating the other side of its distinction: a peripheral modernity and its political system, working under non differentiated forms. we will then describe the operational general frames of a peripheral modernity. what we understand by a world-wide society will be addressed first, continuing with a theoretical approach suitable to observe a peripheral modernity and its political system. then, we will outline the political evolution and how it has operated in latin america through the distinction inclusion/exclusion. finally we will describe some mechanisms acting as functional equivalents, to close with some final reflections.
Para superar el estancamiento económico en México: "nudos críticos" de un proyecto nacional de desarrollo
Guillén R., Arturo;
Revista de Economia Política , 2007, DOI: 10.1590/S0101-31572007000400005
Abstract: this article is devoted to analyze changes in economic policy to be adopted by mexico if a national development project were implemented. starting from an evaluation of the main economic and political outcomes of vicente?s fox administration, the author proposes an alternative development strategy which permits mexico to overcome economic stagnation. that strategy would be based in recovering the internal market as the dynamical focus of the economy with the purpose of satisfying basic needs of people. to be successful this strategy should to confront the "critical knots" of the neo-liberal model: to reverse the uneven distribution of income; abandoning the fixing of restrictive monetary, fiscal and exchange rate policies; and mobilizing economic surplus by means of a profound revision of debt service schemes. it concludes that to implement a national development project it is required a political and economic strategy to dismantle neoliberalism, which is an antinational structure of power.
The effects of the global economic crisis in Latin America
Guillén R., Arturo;
Revista de Economia Política , 2011, DOI: 10.1590/S0101-31572011000200001
Abstract: the aim of this article is to analyze the current phase of the global crisis and the way it has manifested itself in latin america. the global crisis is the most important capitalist crisis since world war ii. it is a new type of debt-deflation crisis, highlighting the limits of the finance-dominated regime of accumulation and characterized by securitization. latin american countries have not been immune to the global crisis. since it sets limits on globalization, the impossibility of maintaining export-driven accumulation sustained by restrictive monetary and fiscal policies becomes clear. this time, there will be no way out in external markets for any country. that fact will force them to restructure productive systems and search for a way out in domestic markets and in regional spaces for integration.
La política en la periferia de la modernidad Esbozos para su observación en América Latina
ARTURO VALLEJOS R
Cuadernos del Cendes , 2007,
Abstract: El artículo propone observar América Latina desde una sociedad moderna, mundial, diferenciada por funciones, con sistemas autónomos e intransparentes. Ante ella, haremos un delineamiento teórico y metodológico ilustrando históricamente el otro lado de su distinción: una modernidad periférica y su sistema político, los que operarían bajo formas no diferenciadas. Pretendemos describir teóricamente sus marcos generales de operación, exponiendo qué entendemos por sociedad mundial, para pasar a algunos lineamientos teóricos que nos permitan observar una modernidad periférica y su sistema político. Posteriormente esbozaremos la evolución de la política y cómo ha operado en América Latina a través de la distinción inclusión/exclusión. Delinearemos algunos mecanismos que fungen como equivalentes funcionales, y terminaremos con algunas reflexiones. This paper proposes to observe Latin America from a modern, world-wide society differentiated by functions, with independent and non transparent systems. Upon this, we offer a theoretical and methodological delineation illustrating the other side of its distinction: a peripheral modernity and its political system, working under non differentiated forms. We will then describe the operational general frames of a peripheral modernity. What we understand by a world-wide society will be addressed first, continuing with a theoretical approach suitable to observe a peripheral modernity and its political system. Then, we will outline the political evolution and how it has operated in Latin America through the distinction inclusion/exclusion. Finally we will describe some mechanisms acting as functional equivalents, to close with some final reflections.
Literatura y poder: una interpretación en clave simbólica de Los girasoles ciegos
José Palomares
Impossibilia : Revista Internacional de Estudios Literarios , 2012,
Abstract: This article aims to provide a symbolic reading of Los girasoles ciegos (2004) through twoconcepts: light and darkness. This paper deals with the meaning of the title, and it comments thedisposition in the narrative structure of the novel, and the value of duality in every chapter of AlbertoMéndez’s work (1941-2004).
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