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índice de masa corporal y perfil lipídico en adolescentes venezolanos de la región centro norte costera
Solángel Higuera, Melissa Arria, Yadira Vera, Rafael Sanz 150
Acta Cientifica Estudiantil , 2009,
Abstract: La adolescencia es un período importante en eldesarrollo humano, debido a todos los cambiosfisiológicos, físicos y psicológicos que ocurren y quepueden afectar el bienestar nutricional del adolescente.Un reflejo de ello es la obesidad, cuyo desarrollodurante las etapas de crecimiento y maduracióndetermina su presencia en la edad adulta; para ello sedeterminó el índice de masa corporal (IMC) y su relacióncon los lípidos séricos, como indicadores del estadonutricional, así como de riesgo para enfermedadescardiovasculares. La investigación se realizó en 1.776individuos de ambos sexos, con edades comprendidasentre 12 y 19,99 a os, seleccionados de cinco estadosvenezolanos (Aragua, Carabobo, Distrito Capital,Miranda y Vargas). El análisis de los datos incluyómedidas de tendencia central y de dispersión, pruebasde ANOVA, y pruebas Post Hoc. En los adolescentesevaluados la prevalencia del IMC por encima delpercentil 90 estuvo entre 14 y 18,7%, siendo mayor enlas adolescentes; a medida que fue aumentando el IMC,fue incrementándose los niveles de colesterol totalsiendo significativamente mayores en el sexo femenino.Aquellos adolescentes femeninos y masculinos, quepresentaron IMC en exceso, presentaron nivelessignificativamente mayores de triglicéridos con respectoa aquellos con un IMC en déficit e IMC adecuado,siendo mayores en las adolescentes; se observótambién que fue descendiendo los niveles de HDL; sinembargo estos niveles de lípidos séricos resultaronadecuados tanto para los individuos del sexo masculinocomo femenino.
Intestinal Parasitic Infections among Pregnant Women in Venezuela
Alfonso J. Rodríguez-Morales,Rosa A. Barbella,Cynthia Case,Melissa Arria
Infectious Diseases in Obstetrics and Gynecology , 2006,
Abstract: Introduction. Intestinal parasitic infections, especially due to helminths, increase anemia in pregnant women. The results of this are low pregnancy weight gain and IUGR, followed by LBW, with its associated greater risks of infection and higher perinatal mortality rates. For these reasons, in the setting of no large previous studies in Venezuela about this problem, a national multicentric study was conducted. Methods. Pregnant women from nine states were studied, a prenatal evaluation with a coproparasitological study. Univariated and multivariated analyses were made to determine risk factors for intestinal parasitosis and related anemia. Results. During 19 months, 1038 pregnant women were included and evaluated. Intestinal parasitosis was evidenced in 73.9%: A lumbricoides 57.0%, T trichiura 36.0%, G lamblia 14.1%, E hystolitica 12.0%, N americanus 8.1%, E vermicularis 6.3%, S stercoralis 3.3%. Relative risk for anemia in those women with intestinal parasitosis was 2.56 ( P<.01 ). Discussion. Intestinal parasitoses could be associated with conditions for development of anemia at pregnancy. These features reflect the need of routine coproparasitological study among pregnant women in rural and endemic zones for intestinal parasites. Further therapeutic and prophylactic protocols are needed. Additional research on pregnant intestinal parasitic infection impact on newborn health is also considered.
Diferencias entre la hemoglobina observada y estimada por hematocrito y su importancia en el diagnóstico de anemia en población costera venezolana: análisis del segundo estudio nacional de crecimiento y desarrollo humano (SENACREDH) Differences between observed and estimated by hematocrit hemoglobin and its relevance in the diagnosis of anemia among coastal population in Venezuela: analysis of the second national study of human growth and development (SENACREDH)
Jessica Flores-Torres,María Echeverría-Ortega,Melissa Arria-Bohorquez,Glida Hidalgo
Revista Peruana de Medicina Experimental y Salud Pública , 2011,
Abstract: Objetivos. Evaluar las diferencias entre el valor de hemoglobina observada y el valor estimado a partir del hematocrito en el marco del Segundo Estudio Nacional de Crecimiento y Desarrollo Humano de la Población Venezolana (SENACREDH) en el eje centro norte costero del país. Materiales y métodos. Por medio de un muestreo probabilístico multietápico por conglomerados se seleccionó un total de 6004 sujetos que representan 7 286 781 habitantes del eje Centro Norte Costero (Vargas, Carabobo, Distrito Capital, Aragua y Miranda). Se compararon medias de la hemoglobina observada y hemoglobina estimada (hematocrito/3), usando la prueba t para muestras relacionadas. Se realizaron regresiones lineales entre hemoglobina observada y hematocrito. Resultados. Se observó que el promedio de las diferencias entre la asignadas a la hemoglobina observada y la estimada por el hematocrito fue de -0,3446 ± 0,0002 (p<0,001); sobreestimando significativamente los valores de hemoglobina. Modelos de regresión del hematocrito para la hemoglobina arrojan un valor de r2=0,87. Al corregir la estimación, se propone una nueva forma de calcularla, con la siguiente fórmula: hemoglobina estimada = (hematocrito/3,135) + 0,257. Conclusiones. Existe una sobreestimación de hemoglobina y, por tanto, subestimación de la prevalencia de anemia a partir del hematocrito; sin embargo, se encuentra una alta correlación entre ambos componentes que permite modelar una mejor estimación de la hemoglobina a partir del hematocrito. Objectives. To evaluate the differences between the observed hemoglobin levels and those estimated based on hematocrit in the context of the 2nd National Study of Human Growth and Development of the Venezuelan Population (SENACREDH). Materials and methods. 6,004 individuals were chosen by a probabilistic multistage cluster sampling representing 7,286,781 inhabitants from North Central Coastal area (Vargas, Carabobo, Capital District, Aragua and Miranda). Means of observed and estimated hemoglobin (hematocrit/3) were compared, using t test for related samples and linear regression. Results. Mean difference between the values of observed and estimated hemoglobin was -0.3446 ±0.0002 (p<0.001); significantly overestimating the hemoglobin values. Regression models of hemoglobin on hematocrit showed an r2=0,87. In order to correct the estimation, we propose a new formula for calculating hemoglobin based on haematocrit values: estimated hemoglobin=(Haematocrit/3.135)+ 0.257. Conclusions: There is an overestimation of hemoglobin levels from hematocrit levels and therefore an underestim
Haemoglobin and haematocrit: the threefold conversion is also non valid for assessing anaemia in Plasmodium vivax malaria-endemic settings
Alfonso J Rodríguez-Morales, Elia Sánchez, Melissa Arria, Miguel Vargas, Carmelina Piccolo, Rosa Colina, Carlos Franco-Paredes
Malaria Journal , 2007, DOI: 10.1186/1475-2875-6-166
Abstract: Carneiro et al [1] recently reported that the standard threefold conversion from haematocrit to haemoglobin underestimates the prevalence of anaemia and low levels of haemoglobin in children under five years of age in malaria endemic settings.In agreement with Carneiro et al findings, demonstrating that the usual threefold conversion represents a significant bias when haemoglobin (Hb) is estimated based on haematocrit (Hct) values in children with malaria, the present report describes the experience in a vivax malaria-endemic zone in northeastern Venezuela. It has been a widely accepted assumption that this conversion could be used as an alternative measurement to haemoglobin in malaria studies [2]. This is particularly important in African settings where Plasmodium falciparum malaria is endemic, but the corresponding haemoglobin levels cannot be derived with an acceptable accuracy using the value three as a conversion factor [2]. As a consequence, the relationship between haematocrit and haemoglobin needs to be specifically evaluated according to each particular region or epidemiological setting. In order to illustrate this important issue, the experience in a malaria-endemic zone in northeastern Venezuela (state of Sucre) is described [3,4], showing a similar bias between haematocrit and haemoglobin in patients with Plasmodium vivax infection.Data from one study that have measured haemoglobin and haematocrit was used to assess the reliability of the standard threefold conversion factor. Finger-prick blood samples were collected for determination of anaemia status from 120 patients with malaria aged 4–89 years-old from a prospective survey carried out between 2000 and 2002 in Carupano, Sucre, Venezuela [5]. In this study, haemoglobin concentration was assessed by haemophotometry and haematocrit was assessed by centrifugation using standard procedures for microhaematocrit tubes and centrifuge (i.e. 10 minutes at a fixed speed of 11,000 rpm).As described by Carneiro
Diferencias entre la hemoglobina observada y estimada por hematocrito y su importancia en el diagnóstico de anemia en población costera venezolana: análisis del segundo estudio nacional de crecimiento y desarrollo humano (SENACREDH)
Flores-Torres,Jessica; Echeverría-Ortega,María; Arria-Bohorquez,Melissa; Hidalgo,Glida; Albano-Ramos,Carlos; Sanz,Rafael; Rodríguez-Morales,Alfonso J.;
Revista Peruana de Medicina Experimental y Salud Pública , 2011, DOI: 10.1590/S1726-46342011000100008
Abstract: objectives. to evaluate the differences between the observed hemoglobin levels and those estimated based on hematocrit in the context of the 2nd national study of human growth and development of the venezuelan population (senacredh). materials and methods. 6,004 individuals were chosen by a probabilistic multistage cluster sampling representing 7,286,781 inhabitants from north central coastal area (vargas, carabobo, capital district, aragua and miranda). means of observed and estimated hemoglobin (hematocrit/3) were compared, using t test for related samples and linear regression. results. mean difference between the values of observed and estimated hemoglobin was -0.3446 ±0.0002 (p<0.001); significantly overestimating the hemoglobin values. regression models of hemoglobin on hematocrit showed an r2=0,87. in order to correct the estimation, we propose a new formula for calculating hemoglobin based on haematocrit values: estimated hemoglobin=(haematocrit/3.135)+ 0.257. conclusions: there is an overestimation of hemoglobin levels from hematocrit levels and therefore an underestimation of the prevalence of anemia; however, a high positive correlation between them was found, allowing modeling for achieving a better estimation of the hemoglobin from the hematocrit value.
La Trimetazidina Disminuye la Glicemia Basal en Ratas con Hiperglicemia de Ayuno
Cano,Clímaco; Bermúdez,Valmore; Souki,Aida; Amell,Anilsa; Restrepo,Helen; Leal,Elliuz; Espinoza,Santiago; Seyfi,Hamid; Arria,Melissa; Rojas,Joselyn; Medina,Mayerlim; Nú?ez,Maryluz; Bermúdez A,Fernando;
Archivos Venezolanos de Farmacología y Terapéutica , 2000,
Abstract: trimetazidine (tmz) is a drug with cardioprotective properties used in coronary artery disease. its effect has been attributed to inhibition of the long chain fatty acids intra-mitochondrial transport via carnitin-palmitoil-transferase- 1. clinical evidence supports the possibility that tmz is able to improve the fasting hyperglycemia in diabetic patients. for this reason, the objective of the present study was to determine the effect of tmz on plasma glucose of sprague-dawley rats under fasting hyperglycaemia. all the a animals received water and food "ad libitum" and two daily tmz doses (1 mg/kg) during 30 days. in order to complete the study, were collected (in fasting period) two blood samples, the last day of treatment (30th day) and 15 days post-treatment and processed with the purpose of evaluate the concentration of plasma glucose. the fasting glycaemia after 30 days of tmz administration, diminished significantly from 141,27 ± 3,31 mg/dl to 120,90 ± 5,84 mg/dl (p <0,01). fifteen days after firnishing treatment, the fasting plasma glucose levels increased again (from 12o,90 ± 5,84 to 137,09 ± 7,08 mg/dl) (p< 0,05). these data suggest that tmz improves glucose utilization by activation of the glucolitic pathway in muscular and hepatic cells to the disminish hyperglycaemic state in diabetic rats.
Chlamydia trachomatis infection among asymptomatic pregnant women attending
Cueva Gómez Janeth, Mezones Holguín Edward, La Madrid Razurí Francisco, Castro Cruz Miguel, Holguín Mauricci Carlos, Valdes García Patricio, Arria Melissa, Rodríguez Morales Alfonso J.
Acta Cientifica Estudiantil , 2009,
Abstract: A cross-sectional descriptive study was conducted among asymptomatic pregnant women attending an antenatal clinic in Piura, northern Peru. Structured questionnaires were used to collect demographic and behavioral information, and clinical and gynecologic examinations were performed to detect clinical signs of infection. Cervical swabs were collected to detect the infection due to C. trachomatis using the direct immunofluorescence technique.C. trachomatis infection was detected in 11 (22%) of the 50 asymptomatic pregnant women. Multiple logistic regression analysis indicated that history of previous abortions (OR = 7.73) and history of previous sexually transmitted infections (STI) (OR = 4.45) were significant independent risk factors for chlamydial infection (P<0.05).A substantial prevalence of C. trachomatis infection in this asymptomatic pregnant women population was found in the study area. These results support a strategy of screening pregnant women for bacterial STIs (followed by treatment of infections), which could be integrated into routine pregnancy care in northern Peru.
Transforming Energy Usage: It’s Not Only about Solar  [PDF]
Melissa Matlock
Open Journal of Energy Efficiency (OJEE) , 2014, DOI: 10.4236/ojee.2014.32004
Abstract:

GRID Alternatives, a non-profit solar contractor, installs solar electric systems for low-income families. Part of GRID Alternatives’ program is to provide solar electric systems that are designed to replace 75% of the homeowners’ electricity usage with solar power. This leaves 25% of their bill still to be paid. In order to save our resources, one must first use conservation practices, then energy efficiency, and then follow-up with renewable energy to cover the rest. GRID Alternatives Inland Empire (GRID IE) educates our participating homeowners and community members on this philosophy. However, measuring whether or not our families have been following this philosophy is hard to prove. It may seem obvious that if we want to know whether our homeowners are saving energy, we should look at their energy usage before and after solar. However, this is not the case with our low-income families that could be using electricity to make their lives more comfortable. GRID IE developed a survey to be given before homeowners received their solar systems and started their participation with GRID Alternatives and the same survey to be given after they have received their solar systems. This before and after survey (pre-test/post-test) asked our homeowners to rate their responses to 7 questions on a scale of 1 - 10. The before and after responses for each person were compared, and as a group, their differences were calculated to find out if the differences were statistically significance (within subjects, dependent Z test). 6 out of 7 questions showed statistical significance. The big picture is that change is happening among our low-income homeowners and has happened for many of the varied energy saving methods discussed. It is important to transform energy usage, because the solution is not just solved with solar.

Latinas’ Experience of Sexual Assault Disclosure  [PDF]
Melissa Villarreal
Psychology (PSYCH) , 2014, DOI: 10.4236/psych.2014.510140
Abstract:

This study describes Latina’s experience of sexual assault disclosure. This study contributes Latinas’ voices to the literature on sexual assault disclosure, about feelings experienced during the initial disclosure—regret, shame, and negative judgment of self, and about consequences experienced from the disclosure—feeling spoiled for marriage, silenced, and disbelieved. It points to the need for further research on social interventions to empower Latina sexual assault survivors. Although the literature review identified some research in the area of sexual assault with Latinas, there has been a limited amount of research conducted on feelings and consequences experienced specifically by Latinas during a sexual assault disclosure.

Intestinal Parasitic Infections Among Pregnant Women in Venezuela
Alfonso J. Rodríguez-Morales,Rosa A. Barbella,Cynthia Case,Melissa Arria,Marisela Ravelo,Henry Perez,Oscar Urdaneta,Gloria Gervasio,Nestor Rubio,Andrea Maldonado,Ymora Aguilera,Anna Viloria,Juan J. Blanco,Magdary Colina,Elizabeth Hernández,Elianet Araujo,Gilberto Cabaniel,Jesús Benitez,Pedro Rifakis
Infectious Diseases in Obstetrics and Gynecology , 2006, DOI: 10.1155/idog/2006/23125
Abstract: Introduction. Intestinal parasitic infections, especially due to helminths, increase anemia in pregnant women. The results of this are low pregnancy weight gain and IUGR, followed by LBW, with its associated greater risks of infection and higher perinatal mortality rates. For these reasons, in the setting of no large previous studies in Venezuela about this problem, a national multicentric study was conducted. Methods. Pregnant women from nine states were studied, a prenatal evaluation with a coproparasitological study. Univariated and multivariated analyses were made to determine risk factors for intestinal parasitosis and related anemia. Results. During 19 months, 1038 pregnant women were included and evaluated. Intestinal parasitosis was evidenced in 73.9%: A lumbricoides 57.0%, T trichiura 36.0%, G lamblia 14.1%, E hystolitica 12.0%, N americanus 8.1%, E vermicularis 6.3%, S stercoralis 3.3%. Relative risk for anemia in those women with intestinal parasitosis was 2.56 (P<.01). Discussion. Intestinal parasitoses could be associated with conditions for development of anemia at pregnancy. These features reflect the need of routine coproparasitological study among pregnant women in rural and endemic zones for intestinal parasites. Further therapeutic and prophylactic protocols are needed. Additional research on pregnant intestinal parasitic infection impact on newborn health is also considered.
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