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Search Results: 1 - 10 of 49921 matches for " Antonio Antunes;Dias Neto "
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Correlation between the presence of inguinal hernia and the intensity of lower urinary tract symptoms
Reis, Rodolfo Borges dos;Rodrigues Neto, Antonio Antunes;Reis, Leonardo Oliveira;Machado, Roberto Dias;Kaplan, Steven;
Acta Cirurgica Brasileira , 2011, DOI: 10.1590/S0102-86502011000800023
Abstract: purpose: to verify the correlation between the presence of ih and the intensity of luts related to bph quantified through the international prostate symptom score (ipss). methods: we prospectively selected 52 patients over the age of 55years; patients were divided into 2 groups. group 1: composed of 32 patients with ih; group 2 (control group): composed of 20 patients with no clinical evidence of ih. all patients were assessed using the ipss, uroflowmetry (qmax), post-void residual urine volume (pvr) and prostate volume (pv). results: groups 1 and 2 presented no difference in pv (p>0.05) and uroflowmetry (qmax) (p>0.05). there was a statistical significant difference between the pvr mean values between groups 1 and 2. the presence of ih correlated with a higher ipss score (r=0.38 p<0.05) despite the fact the no difference was detected between the incidence of patients with mild, moderate and severe luts in groups 1 and 2. conclusion: patients with ih present higher ipss. the role of ipss as a marker to predict the development of clinical ih still to be determined.
A??o do citrato de sildenafil sobre a fun??o uretral de ratas com desnerva??o vesical
Suaid, Haylton Jorge;Cologna, Adauto José;Martins, Antonio Carlos Pereira;Tucci Jr, Silvio;Rodrigues, Antonio Antunes;Dias Neto, José Anastácio;
Acta Cirurgica Brasileira , 2003, DOI: 10.1590/S0102-86502003001200010
Abstract: background: nitric oxide acts as a non-adrenergic and non-cholinergic neurotransmitter in the bladder and urethra. it activates the guanilatocyclase that transforms gmp in cgmp which promotes muscle relaxation. sildenafil citrate increases the cgmp concentration by inhibiting the phosphodiesterase responsible for its hydrolysis. methods: 6 female rats weighing 200g were anesthetized with urethane at a dosage of 1.25mg/kg. all animals underwent cystostomy with a catheter p50 connected by a y to an infusion pump and to a polygraph narco-biosystem. the cystometry was performed trice in each animal: right after the cystostomy, after surgical of bladder denervation and 1h after gastric infusion of 1mg/kg of sildenafil citrate. maximum (map) and minimum (mip) vesical pressure were compared in the following moments: i - before bladder denervation, ii - after bladder denervation and iii - after bladder denervation and sildenafil administration. wilcoxon test was used for a level of significance of 5%. results: mean values of map were: i - 86.6±10.1, ii - 42.6±15.0 and iii - 30.8±12.4. the corresponding values of mip were: : i - 72.1±18.9, ii - 31.1±9.8 and iii - 14.5±9.5. the comparison between map and mip in each moment showed difference only in moment iii (p<0.01). for map p value was <0.002 in ixii and ixiii and >0.05 in iixiii. for mip the p values were <0.004 in ixii, <0.002 in ixiii and <0.01 in iixiii. conclusion: 1) bladder denervation reduces maximum and minimum urethral pressure; 2) sildenafil citrate reduces the minimum urethral pressure widening the interval between the peak and bottom pressures; and, 3) sildenafil citrate does not interfere on the peak urethral pressure after bladder denervation.
Nonextensivity and Tsallis Entropy in DNA Fragmentation Patterns by Ionizing Radiation  [PDF]
Carlos Antonio Marante Valdés, Fidel Antonio Castro Smirnov, Oscar Rodríguez Hoyos, Jo?o Dias de Toledo Arruda-Neto
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.36059
Abstract: Nonextensive statistical mechanics as in Tsallis formalism was used in this study, along with the dynamical Hamiltonian rod-like DNA model and the maximum entropy criteria for Tsallis’ entropy, so as to obtain length distribution of plasmid fragments, after irradiation with very high doses, assuming that the system reaches metaequilibrium. By intensively working out the Grand Canonical Ensemble (used to take into account the variation of the number of base pairs) a simplified expression for Fragment Size Distribution Function (FSDF) was obtained. This expression is dependent on two parameters only, the Tsallis q value and the minimal length of the fragments. Results obtained from fittings to available experimental data were adequate and the characteristic behavior of the shortest fragments was clearly documented and reproduced by the model, a circumstance never verified from theoretical distributions. The results point to the existence of an entropy which characterizes fragmentation processes and depending only on the q entropic index.
Escala diagramática para avalia??o de mofo cinzento (Amphobotrys ricini) da mamoneira (Ricinus communis L.)
Chagas, Haroldo Antunes;Basseto, Marco Antonio;Rosa, Daniel Dias;Zanotto, Maurício Dutra;Furtado, Edson Luiz;
Summa Phytopathologica , 2010, DOI: 10.1590/S0100-54052010000200011
Abstract: the aim of the present study was to develop a diagrammatic scale to assess gray mold caused by amphobotrys ricini in castor bean (ricinus communis l.). the experiment included 59 clusters, which were disinfected in solution of sodium hypochlorite to 2% for 30 seconds and distilled water and sterilized. then, they were packed in moistened foam trays which received 5mm mycelial discs, and were kept in a climatic chamber at 25o c and 80%. rh. the disease evolution was observed daily pictures of the clusters diseased. to determine the severity percentage of the bunches, infected and healthy fruits were counted, estimating thus the percentage of the injured area, and developing a diagrammatic scale with six severity levels. the adoption of the proposed scale, improved the accuracy (r2 = 0,94) "a" values were not significantly different from zero (0) and "b" values were not significantly different from one (1).
Nutritional assessment and weight-height development of sickle cell children in Northeast Brazil
Maria de Fátima Rebou?as Antunes,Jose Brand?o Neto,Carlos Antonio Bruno da Silva
Revista Brasileira em Promo??o da Saúde , 2009,
Abstract: Objective: To evaluate the weight-height development and the nutritional status of a sickle cell anemia infantile sample in relation to zinc seric levels and to bone age in comparison to a control group of eutrophic children of the same Brazilian region. Methods: There were studied 66 sickle cell children (GE) and 50 eutrophic ones (GC). The nutritional status was assessed using Rohrer Index, Z-score analysis of weight/age, height/age and body mass index (BMI). Zinc seric level (SZn), growth velocity (VC) and bone age (IO) were assessed using the standards of the National Center for Health Statistic (NCHS) data and the results obtained from the GC evaluation. Results: Both groups had similar Rohrer Index. GE presented weight/age and height/age Z scores and BMI of underdevelopment levels with significant statistical difference. VC and IO were also lower in GE. The mean SZn in GE was significantly lower than in GC. Conclusion: The studied sickle cell children were born with normal stature, after that an important decrease in weight-height development occurred, which may be related to under-nourishing status, bone age delay, smaller growth velocity and worse zinc seric levels.
Efeitos da simula??o da solariza??o do solo com materiais vegetais sobre o crescimento micelial de fungos fitopatogênicos habitantes do solo
Basseto, Marco Antonio;Bueno, César Júnior;Chagas, Haroldo Antunes;Rosa, Daniel Dias;Padovani, Carlos Roberto;Furtado, Edson Luiz;
Summa Phytopathologica , 2011, DOI: 10.1590/S0100-54052011000300006
Abstract: the incorporation of plant materials associated with soil solarization has been a promising progress to control soilborne phytopathogenic fungi. the aim of this study was to evaluate certain effects of incorporation and decomposition of broccolis, castor bean, wild and sweet cassava, in the soil, under microcosm conditions maintained in bod (37±2oc), on the mycelium of fusarium oxysporum f. sp. lycopersici race 2, macrophomina phaseolina, rhizoctonia solani ag-4 hgi and sclerotium rolfsii. thus, four identical experiments were established with five treatments of four different and independent periods (7, 14, 21 and 28 days). the assessed parameter was the innocuous, fungistatic and fungicide effects of the treatments on the mycelium of fungi. fungistatic and fungicide effect was verified for the mycelium of f. oxysporum f. sp. lycopersici race 2, r. solani ag-4 hgi and s. rolfsii. fungi with fungistatic effect presented lower velocity of mycelial growth compared to the general control, which consisted of incubation of the fungi at a temperature of 25±2oc. fungicide effect occurred at 21 days of incubation for f. oxysporum and r. solani and at 28 days for s. rolfsii. only innocuous effect was observed for m. phaseolina. the factor that caused fungistatic and fungicide effect on the mycelium of fungi was the association of the temperature of 37±2oc with the period of the treatments. that association also interfered in the mycelial growth velocity of the fungi that showed fungistatic effect.
Community acquired urinary tract infection: etiology and bacterial susceptibility
Dias Neto José Anastácio,Martins Antonio Carlos Pereira,Silva Leonardo Dias Magalh?es da,Tiraboschi Ricardo Brianezi
Acta Cirurgica Brasileira , 2003,
Abstract: PURPOSE: Urinary tract infections (UTI) are one of the most common infectious diseases diagnosed. UTI account for a large proportion of antibacterial drug consumption and have large socio-economic impacts. Since the majority of the treatments begins or is done completely empirically, the knowledge of the organisms, their epidemiological characteristics and their antibacterial susceptibility that may vary with time is mandatory. OBJECTIVE: The aim of this study was to report the prevalence of uropathogens and their antibiotic susceptibility of the community acquired UTI diagnosed in our institution and to provide a national data. METHODS: We analyzed retrospectively the results of urine cultures of 402 patients that had community acquired urinary tract infection in the year of 2003. RESULTS: The mean age of the patients in this study was 45.34 ± 23.56 (SD) years. There were 242 (60.2%) females and 160 (39.8%) males. The most commonly isolated organism was Escherichia coli (58%). Klebsiella sp. (8.4%) and Enterococcus sp.(7.9%) were reported as the next most common organisms. Of all bacteria isolated from community acquired UTI, only 37% were sensitive to ampicillin, 51% to cefalothin and 52% to trimethoprim/sulfamethoxazole. The highest levels of susceptibility were to imipenem (96%), ceftriaxone (90%), amikacin (90%), gentamicin (88%), levofloxacin (86%), ciprofloxacin (73%), nitrofurantoin (77%) and norfloxacin (75%). CONCLUSION: Gram-negative agents are the most common cause of UTI. Fluoroquinolones remains the choice among the orally administered antibiotics, followed by nitrofurantoin, second and third generation cephalosporins. For severe disease that require parenteral antibiotics the choice should be aminoglycosides, third generation cephalosporins, fluoroquinolones or imipenem, which were the most effective.
Prevalence and bacterial susceptibility of hospital acquired urinary tract infection
Dias Neto José Anastácio,Silva Leonardo Dias Magalh?es da,Martins Antonio Carlos Pereira,Tiraboschi Ricardo Brianezi
Acta Cirurgica Brasileira , 2003,
Abstract: PURPOSE: Urinary tract infection is the most common nosocomially acquired infection. It is important to know the etiology and antibiotic susceptibility infectious agents to guide the initial empirical treatment. OBJECTIVE: To determine the prevalence of bacterial strains and their antibiotic susceptibility in nosocomially acquired urinary tract infection in a university hospital between January and June 2003. METHODS: We analyzed the data of 188 patients with positive urine culture (= 10(5) colony-forming units/mL) following a period of 48 hours after admission. RESULTS: Half of patients were male. Mean age was 50.26 ± 22.7 (SD), range 3 months to 88 years. Gram-negative bacteria were the agent in approximately 80% of cases. The most common pathogens were E. coli (26%), Klebsiella sp. (15%), P. aeruginosa (15%) and Enterococcus sp. (11%). The overall bacteria susceptibility showed that the pathogens were more sensible to imipenem (83%), second or third generation cephalosporin and aminoglycosides; and were highly resistant to ampicillin (27%) and cefalothin (30%). It is important to note the low susceptibility to ciprofloxacin (42%) and norfloxacin (43%). CONCLUSION: This study suggests that if one can not wait the results of urine culture, the best choices to begin empiric treatment are imipenem, second or third generation cephalosporin and aminoglycosides. Cefalothin and ampicillin are quite ineffective to treat these infections.
Human eosinophil adhesion and degranulation stimulated with eotaxin and RANTES in vitro: Lack of interaction with nitric oxide
Letícia Lintomen, Gilberto Franchi, Alexandre Nowill, Antonio Condino-Neto, Gilberto de Nucci, Angelina Zanesco, Edson Antunes
BMC Pulmonary Medicine , 2008, DOI: 10.1186/1471-2466-8-13
Abstract: Eosinophils were purified using a percoll gradient followed by immunomagnetic cell separator. Cell adhesion and degranulation were evaluated by measuring eosinophil peroxidase (EPO) activity, whereas expression of Mac-1 and VLA-4 was detected using flow cytometry.At 4 h incubation, both eotaxin (100 ng/ml) and RANTES (1000 ng/ml) increased by 133% and 131% eosinophil adhesion, respectively. L-NAME alone (but not D-NAME) also increased the eosinophil adhesion, but the co-incubation of L-NAME with eotaxin or RANTES did not further affect the increased adhesion seen with chemokines alone. In addition, L-NAME alone (but not D-NAME) caused a significant cell degranulation, but it did not affect the CC-chemokine-induced cell degranulation. Incubation of eosinophils with eotaxin or RANTES, in absence or presence of L-NAME, did not affect the expression of VLA-4 and Mac-1 on eosinophil surface. Eotaxin and RANTES (100 ng/ml each) also failed to elevate the cyclic GMP levels above baseline in human eosinophils.Eotaxin and RANTES increase the eosinophil adhesion to fibronectin-coated plates and promote cell degranulation by NO-independent mechanisms. The failure of CC-chemokines to affect VLA-4 and Mac-1 expression suggests that changes in integrin function (avidity or affinity) are rather involved in the enhanced adhesion.Airway eosinophilia is considered a central event in the pathogenesis of asthma. The toxic components of eosinophils are thought to be important in inducing bronchial mucosal injury and dysfunction [1]. Evidences suggest that recruitment of eosinophils into sites of inflammation is a multifactorial and multistep process, involving eosinophil-endothelial interactions through adhesion molecules and local generation of chemotactic agents that direct cell migration into the inflamed airways [2]. Thus, adhesion molecules and chemokines play key roles in selective eosinophil accumulation [3]. The integrins macrophage adhesion molecule-1 (Mac-1, CD11b/CD18, αMβ2)
Amaurose secundária a mucocele esfenoidal
Melo, Antonio Antunes;Caldas Neto, Sílvio da Silva;Gouveia, Mariana Carvalho Leal;Santos, Patrícia Ferreira;
Arquivos Internacionais de Otorrinolaringologia , 2011, DOI: 10.1590/S1809-48722011000400018
Abstract: introduction: the mucocele of the sphenoide sinus its a benign rare lesion. those lesions are probably diagnosed late because they are asymptomatic or cause non-specific symptoms. the clinical characteristics depend on its location and can include fronto-orbital pain, oculomotor nerve palsy, decrease of visual acuity, exophthalmos and olfaction disorders. the findings of the ct and the mri of nose and paranasal sinuses have increased the diagnostic accuracy. the treatment consists of marsupialization and drainage of the mucocele via endoscopic sinus. the prognosis for vision depends on the length loss of the visual acuity preoperative. objective: report a case of sphenoid mucocele of big dimensions. case report: the authors report a case of sphenoid sinus mucocele in a male patient of 48 years old, that has suddenly presented amaurosis. final comments: the caracteristics of the sphenoid mucocele are reviewed with special attention for the clinical and radiological findings, as well as the surgical treatment.
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