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Search Results: 1 - 10 of 224421 matches for " Antonietta R. Farina "
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The TrkAIII Oncoprotein Inhibits Mitochondrial Free Radical ROS-Induced Death of SH-SY5Y Neuroblastoma Cells by Augmenting SOD2 Expression and Activity at the Mitochondria, within the Context of a Tumour Stem Cell-like Phenotype
Pierdomenico Ruggeri, Antonietta R. Farina, Natalia Di Ianni, Lucia Cappabianca, Marzia Ragone, Giulia Ianni, Alberto Gulino, Andrew R. Mackay
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0094568
Abstract: The developmental and stress-regulated alternative TrkAIII splice variant of the NGF receptor TrkA is expressed by advanced stage human neuroblastomas (NBs), correlates with worse outcome in high TrkA expressing unfavourable tumours and exhibits oncogenic activity in NB models. In the present study, we report that constitutive TrkAIII expression in human SH-SY5Y NB cells inhibits Rotenone, Paraquat and LY83583-induced mitochondrial free radical reactive oxygen species (ROS)-mediated death by stimulating SOD2 expression, increasing mitochondrial SOD2 activity and attenuating mitochondrial free radical ROS production, in association with increased mitochondrial capacity to produce H2O2, within the context of a more tumour stem cell-like phenotype. This effect can be reversed by the specific TrkA tyrosine kinase inhibitor GW441756, by the multi-kinase TrkA inhibitors K252a, CEP-701 and G?6976, which inhibit SOD2 expression, and by siRNA knockdown of SOD2 expression, which restores the sensitivity of TrkAIII expressing SH-SY5Y cells to Rotenone, Paraquat and LY83583-induced mitochondrial free radical ROS production and ROS-mediated death. The data implicate the novel TrkAIII/SOD2 axis in promoting NB resistance to mitochondrial free radical-mediated death and staminality, and suggest that the combined use of TrkAIII and/or SOD2 inhibitors together with agents that induce mitochondrial free radical ROS-mediated death could provide a therapeutic advantage that may also target the stem cell niche in high TrkA expressing unfavourable NB.
Plantas hospedadoras de Cerambycidae (Coleoptera) de la provincia de Buenos Aires, Argentina
Di Iorio,Osvaldo R.; Farina,Juan;
Revista del Museo Argentino de Ciencias Naturales , 2009,
Abstract: the insect-host plants associations for 48 species of cerambycidae (coleoptera) from buenos aires province (argentina) are summarized, including the previous records given in the literature, 12 associations in native plants (11 species of cerambycidae in 6 species of plants) and 50 associations in exotic plants (18 cerambycidae in 16 species of plants). to them are added the previous associations given for the province of the espinal, and the data now gathered of 6239 specimens (34 of prioninae, 4564 of cerambycinae, and 1641 of lamiinae) belonging to 42 species of cerambycidae reared from 108 species of plants. this last data includes 329 associations: 91 (27,6%) of them were found in native plants (36 species of cerambycidae in 24 species of plants), and 240 (72,4%) in exotic plants (69 spp.) and some native plants (15 spp.) cultivated outs of its natural range (29 species of cerambycidae in 84 species of plants). with the amount of localities of each insect- host plant association, the total number of associations increases to 501 records, 199 (39,8%) in native plants and 302 (60,2%) in exotic plants.
Plantas hospedadoras de Cerambycidae (Coleoptera) de la provincia de Buenos Aires, Argentina Host plants of Cerambycidae (Coleoptera) from Buenos Aires province, Argentina
Osvaldo R. Di Iorio,Juan Farina
Revista del Museo Argentino de Ciencias Naturales , 2009,
Abstract: Se enumeran las asociaciones insecto-planta hospedadora para 48 especies de Cerambycidae (Coleoptera) de la provincia de Buenos Aires (Argentina), incluyendo los registros dados previamente en la literatura, 12 asociaciones en plantas nativas (11 especies de Cerambycidae en 6 especies de plantas) y 50 asociaciones en plantas exóticas (18 Cerambycidae en 16 especies de plantas). A ello se suman las asociaciones previamente dadas para la Provincia del Espinal y los datos ahora obtenidos de 6239 especímenes (34 de Prioninae, 4564 de Cerambycinae y 1641 de Lamiinae) pertenecientes a 42 especies de Cerambycidae criados de 108 especies de plantas. Estos últimos comprenden 329 asociaciones: 91 (27,6%) de ellas fueron encontradas en plantas nativas (36 especies de Cerambycidae en 24 especies de plantas) y 240 (72,4%) en plantas exóticas (69 spp.) y algunas plantas nativas (15 spp.) cultivadas fuera de su área natural (29 especies de Cerambycidae en 84 especies de plantas). Con la cantidad de localidades de cada asociación insecto-planta, el número total de asociaciones se incrementa a 501 registros, 199 (39,7%) en plantas nativas y 302 (60,3%) en plantas exóticas. The insect-host plants associations for 48 species of Cerambycidae (Coleoptera) from Buenos Aires province (Argentina) are summarized, including the previous records given in the literature, 12 associations in native plants (11 species of Cerambycidae in 6 species of plants) and 50 associations in exotic plants (18 Cerambycidae in 16 species of plants). To them are added the previous associations given for the Province of the Espinal, and the data now gathered of 6239 specimens (34 of Prioninae, 4564 of Cerambycinae, and 1641 of Lamiinae) belonging to 42 species of Cerambycidae reared from 108 species of plants. This last data includes 329 associations: 91 (27,6%) of them were found in native plants (36 species of Cerambycidae in 24 species of plants), and 240 (72,4%) in exotic plants (69 spp.) and some native plants (15 spp.) cultivated outs of its natural range (29 species of Cerambycidae in 84 species of plants). With the amount of localities of each insect- host plant association, the total number of associations increases to 501 records, 199 (39,8%) in native plants and 302 (60,2%) in exotic plants.
A study of six low redshift QSO pairs
E. P. Farina,R. Falomo,A. Treves
Physics , 2011, DOI: 10.1111/j.1365-2966.2011.18931.x
Abstract: The dynamical properties of six SDSS quasar pairs at z < 0.8 are investigated. The pairs have proper transverse separation < 500 kpc, and velocity difference along the line of sight < 500 km/s. If they are bound systems their dynamical mass can be evaluated and compared with that of host galaxies. Evidence is found of an excess of the former mass with respect to the latter. This suggests that these quasar pairs are hosted by galaxies with massive dark halos or that they reside in a group/cluster of galaxies.
The Interactive Effects of Pulsed Grazing Disturbance and Patch Size Vary among Wetland Arthropod Guilds
Anna R. Armitage, Chuan-Kai Ho, Antonietta Quigg
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0076672
Abstract: Pulse disturbances and habitat patch size can determine community composition independently or in concert, and may be particularly influential on small spatial scales for organisms with low mobility. In a field experiment, we investigated whether the effects of a pulsed disturbance that simulated a grazing event varied with habitat patch size. We focused on the short-term responses of multiple co-occurring emergent salt marsh arthropods with differing levels of mobility and dispersal potential. As part of a marsh restoration project, two types of emergent marsh structures were created: small circular mounds (0.5 m diameter) separated by several meters of aquatic habitat, and larger, elongated terraces (>50 m long). Study plots (0.25 m2) were established on both structures; in a subset of plots, we simulated a pulsed grazing disturbance event by clipping the aboveground tissue of emergent plants, primarily Spartina alterniflora. At the end of the two-month recovery period, Ischnodemus (Hemiptera: Blissidae) density was over 50% lower in disturbed treatments within both large (terrace) and small (mound) patches. Predatory spider treatment responses were similar to Ischnodemus responses, suggesting a trophic relationship between those two arthropod groups. Alternatively, spiders may have been directly affected by the loss of shelter in the disturbed plots. Prokelisia (Homoptera: Delphacidae), which are generally more mobile than Ischnodemus, were not affected by disturbance treatment or by patch size, suggesting the potential for rapid recolonization following disturbance. Larval stem borers decreased by an order of magnitude in disturbed plots, but only in the large patches. In general, the disturbance effects of vegetation removal on arthropod density and community composition were stronger than patch size effects, and there were few interactions between pulsed disturbance and patch size. Rather, emergent marsh arthropod responses to disturbance and habitat area treatments were linked to the dispersal potential and mobility of each individual taxon.
Tietze’s Syndrome in the emergency department: A rare etiology of atraumatic chest pain  [PDF]
Lee Grodin, Gino Farina
Case Reports in Clinical Medicine (CRCM) , 2013, DOI: 10.4236/crcm.2013.23056
Abstract:

Tietze’s Syndrome is an uncommon disorder that presents with painful, tender, non-suppurative swelling of the anterior chest wall. We report a case of a female patient who presented to the emergency department with a chief complaint of atraumatic chest pain and swelling of the anterior chest wall. After a thorough history and physical examination, as well as basic laboratory tests and chest radiography, she was diagnosed with Tietze’s Syndrome. The expedient accurate diagnosis of Tietze’s Syndrome is important for the physical and emotional well-being of a patient, and avoids overlooking more dangerous pathologies. Tietze’s Syndrome needs to be considered in the differential diagnosis of a patient presenting with spontaneous swelling of the anterior chest.

Enhancing Metaphor and Metonymy Comprehension in Children with High-Functioning Autism Spectrum Disorder  [PDF]
Sergio Melogno, Maria Antonietta Pinto
Psychology (PSYCH) , 2014, DOI: 10.4236/psych.2014.511148
Abstract:

This article addresses how to enhance metaphor and metonymy comprehension in children with high-functioning autism spectrum disorder (HF-ASD), who are known to have difficulties with figurative language. After considering some major issues on typical development and in HF-ASD, and some studies on treatment in this specific domain, the authors describe an intervention methodology that can be used in schools and clinics. This methodology is based on two main points: 1) the explicit teaching of strategies for understanding metaphors and 2) activities for enhancing the abstraction of semantic features in metaphors and metonymies. The authors show how these devices can make complex processes such as figurative language comprehension more concrete for children with HF-ASD.

Localized corrosion of zirconium and zircaloy- 4 in iodine alcoholic solutions
Farina,S. B.; Duffo,G. S; Galvele,J. R.;
Latin American applied research , 2002,
Abstract: the stress corrosion cracking (scc) susceptibility of zirconium and one of its alloys, zircaloy-4, was studied in 10 g/l iodine dissolved in various alcohols: methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol. scc was observed in all the systems studied and the crack propagation rate was found to vary depending on the size of the solvent molecule. when the molecular weight of the solvent molecule increased, the crack propagation rate decreased. intergranular attack was also found in all the solutions tested, and the rate of intergranular corrosion also varied with the size of the solvent molecule. this behavior is attributed to a steric effect, which hinders the access of the corrosive species to the tip of the crack. the results found agree with the predictions of the surface mobility-scc mechanism.
Localized corrosion of zirconium and zircaloy- 4 in iodine alcoholic solutions
S. B. Farina,G. S Duffo,J. R. Galvele
Latin American applied research , 2002,
Abstract: The stress corrosion cracking (SCC) susceptibility of zirconium and one of its alloys, Zircaloy-4, was studied in 10 g/L iodine dissolved in various alcohols: methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol. SCC was observed in all the systems studied and the crack propagation rate was found to vary depending on the size of the solvent molecule. When the molecular weight of the solvent molecule increased, the crack propagation rate decreased. Intergranular attack was also found in all the solutions tested, and the rate of intergranular corrosion also varied with the size of the solvent molecule. This behavior is attributed to a steric effect, which hinders the access of the corrosive species to the tip of the crack. The results found agree with the predictions of the surface mobility-SCC mechanism.
One-dimensional motion of a material with a strain theshold ONE-DIMENSIONAL MOTION OF A MATERIAL WITH A STRAIN THRESHOLD
A. Farina,A. Fasano,L. Fusi,K.R. Rajagopal
Le Matematiche , 2007,
Abstract: We consider the one-dimensional shearing motion of a material exhibiting elastic behaviour when the stress is below some threshold. The threshold represents a limit to the deformability, i.e. no further deformation can occur on increasing the stress. The mathematical formulation leads to a free boundary problem for the wave equation, whose structure depends on whether the stress (and the velocity) are continuous across the propagating interface for the strain threshold . Local existence and uniqueness are proved for the continuous case (in which the interface propagation is subsonic). Some explicit solutions are calculated for another case (with a supersonic interface). It is shown that the model with strain threshold is never the limit of hyperelastic systems. We consider the one-dimensional shearing motion of a material exhibiting elastic behaviour when the stress is below some threshold. The threshold represents a limit to the deformability, i.e. no further deformation can occur on increasing the stress. The mathematical formulation leads to a free boundary problem for the wave equation, whose structure depends on whether the stress (and the velocity) are continuous across the propagating interface for the strain threshold . Local existence and uniqueness are proved for the continuous case (in which the interface propagation is subsonic). Some explicit solutions are calculated for another case (with a supersonic interface). It is shown that the model with strain threshold is never the limit of hyperelastic systems.
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