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Search Results: 1 - 10 of 9203 matches for " Antonella Lo Mauro "
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The Abdominal Circulatory Pump
Andrea Aliverti, Dario Bovio, Irene Fullin, Raffaele L. Dellacà, Antonella Lo Mauro, Antonio Pedotti, Peter T. Macklem
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0005550
Abstract: Blood in the splanchnic vasculature can be transferred to the extremities. We quantified such blood shifts in normal subjects by measuring trunk volume by optoelectronic plethysmography, simultaneously with changes in body volume by whole body plethysmography during contractions of the diaphragm and abdominal muscles. Trunk volume changes with blood shifts, but body volume does not so that the blood volume shifted between trunk and extremities (Vbs) is the difference between changes in trunk and body volume. This is so because both trunk and body volume change identically with breathing and gas expansion or compression. During tidal breathing Vbs was 50–75 ml with an ejection fraction of 4–6% and an output of 750–1500 ml/min. Step increases in abdominal pressure resulted in rapid emptying presumably from the liver with a time constant of 0.61±0.1SE sec. followed by slower flow from non-hepatic viscera. The filling time constant was 0.57±0.09SE sec. Splanchnic emptying shifted up to 650 ml blood. With emptying, the increased hepatic vein flow increases the blood pressure at its entry into the inferior vena cava (IVC) and abolishes the pressure gradient producing flow between the femoral vein and the IVC inducing blood pooling in the legs. The findings are important for exercise because the larger the Vbs the greater the perfusion of locomotor muscles. During asystolic cardiac arrest we calculate that appropriate timing of abdominal compression could produce an output of 6 L/min. so that the abdominal circulatory pump might act as an auxiliary heart.
Can nebivolol be helpful in Beh et’s disease?
Antonella Tomassino,Giovan Battista Mauro
Anadolu Kardiyoloji Dergisi , 2013,
Legionella contamination in hot water systems of hospitals, nursing homes, hotels, factories and spas in Tuscany-Italy
Antonella Lo Nostro,Elettra Checchi,Barbara Ducci,Giovanna Pesavento
Italian Journal of Public Health , 2011, DOI: 10.2427/5638
Abstract: Following the report of many cases of Legionnaires’ disease associated with accommodation facilities such as hotels, spas, workplaces, hospitals and nursing homes, we verified if Legionella pneumophila and Legionella spp. were present in some of those structures in Tuscany, in order to estimate the species and serogroups in circulation. Legionella pneumophila serogroup 1 (30.9%) was the most frequently isolated species along with serogroups 3 (16.1%) and 6 (13.3%); these three serogroups are identified, in literature, as those most responsible for Legionnaires’ disease (LD). Studying all analyzed structures, we found some parts of the water system where Legionella concentration was higher than 103CFU/L, indicated, in Italy, as the maximum admitted concentration value above which a decontamination treatment is necessary when one or more cases of healthcare-acquired Legionnaires’ disease are observed. Moreover disinfection is recommended in any case when counts exceed 104CFU/L. Consequently, in order to prevent cases of Legionnaires’ disease, a continuous surveillance of the water systems of all accommodation facilities is necessary, with particular attention to hospitals and nursing homes where immunocompromised patients lodge, so as to promptly estimate the presence of the pathogen and consequently plan the most suitable intervention activities. We concluded that, in any structure, a continuous surveillance and disinfecting treatment of water systems is necessary. Moreover, after any disinfection treatment the temperature of the hot water flowing in the system must be necessarily maintained near 51°C in order to minimize the probability of recontamination from Legionella and limit the risk of LD in consumers.
Imprinting a complete information about a quantum channel on its output state
Giacomo Mauro D'Ariano,Paoloplacido Lo Presti
Physics , 2002, DOI: 10.1103/PhysRevLett.91.047902
Abstract: We introduce a novel property of bipartite quantum states, which we call "faithfulness", and we say that a state is faithful when acting with a channel on one of the two quantum systems, the output state carries a complete information about the channel. The concept of faithfulness can also be extended to sets of states, when the output states patched together carry a complete imprinting of the channel.
Baecklund Transformations and Non Abelian Nonlinear Evolution Equations: a novel Baecklund Chart
Sandra Carillo,Mauro Lo Schiavo,Cornelia Schiebold
Mathematics , 2015,
Abstract: Third order Non Abelian Nonlinear Evolution Equations, such as potential Korteweg deVries (pKdV), Korteweg deVries (KdV) as well as different versions of modified Korteweg deVries (mKdV), and the Korteweg deVries interacting soliton and Korteweg deVries singuarity manifold equations are here considered. In particular a new Baecklund Chart is constructed. Notably it, on one side, generalizes the Abelian Baecklund Chart presented in [24] and, on the other one, extends the noncommutative Baecklund Chart obtained in [12] to incorporate further non Abelian operator equations. The Baecklund transformations which link the various nonlinear evolution equations, allow to write the corresponding recursion operators and, hence, the corresponding whole hierarchies of nonlinear operators equations are connected.
Phototropic sulfur and sulfate-reducing bacteria in the chemocline of meromictic Lake Cadagno, Switzerland
Journal of Limnology , 2004, DOI: 10.4081/jlimnol.2004.161
Abstract: Lake Cadagno, a crenogenic meromictic lake located in the catchment area of a dolomite vein rich in gypsum in the Piora Valley in the southern Alps of Switzerland, is characterized by a compact chemocline with high concentrations of sulfate, steep gradients of oxygen, sulfide and light and a turbidity maximum that correlates to large numbers of bacteria (up to 107 cells ml-1). The most abundant taxa in the chemocline are large- and small-celled purple sulfur bacteria, which account for up to 35% of all bacteria, and sulfate- reducing bacteria that represent up to 23% of all bacteria. Depending on the season, as much as 45% of all bacteria in the chemocline are associated in aggregates consisting of different populations of small-celled purple sulfur bacteria of the genus Lamprocystis (up to 35% of all bacteria) and sulfate-reducing bacteria of the family Desulfobulbaceae (up to 12% of all bacteria) that are almost completely represented by bacteria closely related to Desulfocapsa thiozymogenes. Their association in aggregates is restricted to small-celled purple sulfur bacteria of the genus Lamprocystis, but not obligate since non-associated cells of bacteria related to D. thiozymogenes are frequently found, especially under limited light conditions in winter and early summer. Aggregate formation and concomitant growth enhancement of isolates of both partners of this association suggests synergistic interactions that might resemble a sulfide-based source-sink relationship between the sulfate-reducing bacterium that is able to sustain growth by a disproportionation of inorganic sulfur compounds (sulfur, thiosulfate, sulfite), with the purple sulfur bacteria acting as a biotic scavenger. The availability of these isolates opens up the door for future studies considering other facets of potential interactions in aggregates since both types of organisms are metabolically highly versatile and interactions may not be limited to sulfur compounds only.
Basic analysis of non-European Union immigrants’ hospitalizations and ambulatory care in the province of Ferrara, Northern Italy: the first step to an improved approach to immigrants’ healthcare.
Alessandro Cucchi,Mauro Bergamini,Orazio Buriani,Antonella Ferrari
Italian Journal of Public Health , 2008, DOI: 10.2427/5829
Abstract: Background: Immigration towards Ferrara is a recent occurrence. We evaluated the immigrants’ health requests. Methods: This report is based on data collected by Local Health Authority. Results: The analysis of ambulatory cares and hospitalizations are comparable. It emerges the age class 31- 65 is the most represented. Females’ requests are more than males’ one, due to pregnancy and gynaecological health requests. The capital hospital sustained the heaviest workload. We found differences respect European Union population regarding length of stay. The predominant kind of access are through emergency room and self-access. Conclusions: This complex pattern of health care requests requires dedicated approaches.
Dexamethasone restrains ongoing expression of interleukin-23p19 in peripheral blood-derived human macrophages
Palma Linda,Sfara Carla,Antonelli Antonella,Magnani Mauro
BMC Pharmacology , 2011, DOI: 10.1186/1471-2210-11-8
Abstract: Background Since its recent discovery, interleukin-23 has been shown to be involved in the pathogenesis of autoimmune diseases favoring the development of a T cell subset referred to as T helper 17. Glucocorticoids are widely employed in inflammatory and autoimmune diseases as they inhibit pro-inflammatory signaling and prevent production of inflammation mediators. Very limited information is available about the efficacy of synthetic glucocorticoids in containing the expression of interleukin-23 under cell activation. Results We demonstrate here that the glucocorticoid analogue dexamethasone administered to human monocyte-derived macrophages is indeed able to restrain the expression of interleukin-23 once it has been triggered by a pro-inflammatory stimulus. This effect of dexamethasone is here demonstrated being secondary to suppression of p38 MAPK activity, and involving a protein phosphatase - likely MAPK phosphatase-1 (MKP-1). Conclusions Results reported in this paper show that a 10 nanomolar dose of dexamethasone not only prevents inflammatory activation but is also efficacious in confining active inflammation. This effect is here demonstrated not to occur through "canonical" inhibition of the NF-κB transcription factor but through a distinct cascade of down-modulation, that underlines the importance of the transactivating activity of glucocorticoid receptor in the context of its anti-inflammatory action.
Detection and Characterization of Leishmania (Leishmania) and Leishmania (Viannia) by SYBR Green-Based Real-Time PCR and High Resolution Melt Analysis Targeting Kinetoplast Minicircle DNA
Marcello Ceccarelli, Luca Galluzzi, Antonella Migliazzo, Mauro Magnani
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0088845
Abstract: Leishmaniasis is a neglected disease with a broad clinical spectrum which includes asymptomatic infection. A thorough diagnosis, able to distinguish and quantify Leishmania parasites in a clinical sample, constitutes a key step in choosing an appropriate therapy, making an accurate prognosis and performing epidemiological studies. Several molecular techniques have been shown to be effective in the diagnosis of leishmaniasis. In particular, a number of PCR methods have been developed on various target DNA sequences including kinetoplast minicircle constant regions. The first aim of this study was to develop a SYBR green-based qPCR assay for Leishmania (Leishmania) infantum detection and quantification, using kinetoplast minicircle constant region as target. To this end, two assays were compared: the first used previously published primer pairs (qPCR1), whereas the second used a nested primer pairs generating a shorter PCR product (qPCR2). The second aim of this study was to evaluate the possibility to discriminate among subgenera Leishmania (Leishmania) and Leishmania (Viannia) using the qPCR2 assay followed by melting or High Resolution Melt (HRM) analysis. Both assays used in this study showed good sensitivity and specificity, and a good correlation with standard IFAT methods in 62 canine clinical samples. However, the qPCR2 assay allowed to discriminate between Leishmania (Leishmania) and Leishmania (Viannia) subgenera through melting or HRM analysis. In addition to developing assays, we investigated the number and genetic variability of kinetoplast minicircles in the Leishmania (L.) infantum WHO international reference strain (MHOM/TN/80/IPT1), highlighting the presence of minicircle subclasses and sequence heterogeneity. Specifically, the kinetoplast minicircle number per cell was estimated to be 26,566±1,192, while the subclass of minicircles amplifiable by qPCR2 was estimated to be 1,263±115. This heterogeneity, also observed in canine clinical samples, must be taken into account in quantitative PCR-based applications; however, it might also be used to differentiate between Leishmania subgenera.
Quantum calibration of measuring apparatuses
Giacomo Mauro D'Ariano,Lorenzo Maccone,Paoloplacido Lo Presti
Physics , 2004,
Abstract: By quantum calibration we name an experimental procedure apt to completely characterize an unknown measurement apparatus by comparing it with other calibrated apparatuses. Here we show how to achieve the calibration of an arbitrary measuring apparatus, by using it in conjunction with a ``tomographer'' in a correlation setup with an input bipartite system. The method is robust to imperfections of the tomographer, and works for practically any input state of the bipartite system.
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