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Search Results: 1 - 10 of 692 matches for " Annalisa Noce "
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Safety Food in Celiac Disease Patients: A Systematic Review  [PDF]
Mariarita Dessì, Annalisa Noce, Sara Vergovich, Gianluca Noce, Nicola Di Daniele
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.47A008
Abstract: The prevalence of Celiac Disease (CD), an autoimmune enteropathy, characterized by chronic inflammation of the intestinal mucosa, atrophy of intestinal villi and several clinical manifestations has increased in recent years. Epidemiological studies have shown that CD is very common and affects about one in 250 people. The mechanism of the intestinal immune-mediated response is not completely clear, but involves an HLA-DQ2 or HLA-DQ8 restricted T-cell immune reaction in the lamina propria as well as an immune reaction in the intestinal epithelium. Subjects affected by CD cannot tolerate gluten protein, a mixture of storage proteins contained in several cereals (wheat, rye, barley and derivatives). Gluten free-diet remains the cornerstone treatment for celiac patients. Therefore the absence of gluten in natural and processed foods represents a key aspect of food safety of the gluten-free diet. In this review, we evaluate the main studies about the safety food in CD patients.
Obesity-Related Metabolic Syndrome: Mechanisms of Sympathetic Overactivity
Maria Paola Canale,Simone Manca di Villahermosa,Giuliana Martino,Valentina Rovella,Annalisa Noce,Antonino De Lorenzo,Nicola Di Daniele
International Journal of Endocrinology , 2013, DOI: 10.1155/2013/865965
Abstract: The prevalence of the metabolic syndrome has increased worldwide over the past few years. Sympathetic nervous system overactivity is a key mechanism leading to hypertension in patients with the metabolic syndrome. Sympathetic activation can be triggered by reflex mechanisms as arterial baroreceptor impairment, by metabolic factors as insulin resistance, and by dysregulated adipokine production and secretion from visceral fat with a mainly permissive role of leptin and antagonist role of adiponectin. Chronic sympathetic nervous system overactivity contributes to a further decline of insulin sensitivity and creates a vicious circle that may contribute to the development of hypertension and of the metabolic syndrome and favor cardiovascular and kidney disease. Selective renal denervation is an emerging area of interest in the clinical management of obesity-related hypertension. This review focuses on current understanding of some mechanisms through which sympathetic overactivity may be interlaced to the metabolic syndrome, with particular regard to the role of insulin resistance and of some adipokines. 1. Introduction The metabolic syndrome (MetS) is a cluster of abnormalities that include diabetes mellitus (DM), morbid obesity, dyslipidemia, and hypertension (HT) that are all risk factors for the development of cardiovascular disease (CVD) and chronic kidney disease (CKD) [1]. The National Cholesterol Education Program’s Adult Treatment Panel III report (ATP III) identified six components of the MetS that relate to CVD: abdominal obesity, atherogenic dyslipidemia, raised blood pressure (BP), insulin resistance (I.R.)/glucose intolerance, and proinflammatory and prothrombotic state [2]. A major problem concerning the WHO and NCEP ATPIII definitions was their applicability to different ethnic groups, especially when obesity cutoffs were to be defined. This is particularly evident for the risk of type II DM, which may be associated with much lower levels of obesity in Asians compared to Caucasians. The International Diabetes Federation has then proposed a new set of criteria with ethnic/racial specific cutoffs [3]. The MetS central feature is obesity, and the MetS is a growing epidemic in the United States and throughout the world [4, 5]. Approximately 1 adult in 4 or 5, depending on the country, has the MetS. Incidence increases with age; it has been estimated that in people over 50 years of age, the MetS affects more than 40% of the population in the United States and nearly 30% in Europe [6, 7]. Whether the effects of the MetS are due to a sum of
Atherosclerosis, Dyslipidemia, and Inflammation: The Significant Role of Polyunsaturated Fatty Acids
Mariarita Dessì,Annalisa Noce,Pierfrancesco Bertucci,Simone Manca di Villahermosa,Rossella Zenobi,Veronica Castagnola,Eliana Addessi,Nicola Di Daniele
ISRN Inflammation , 2013, DOI: 10.1155/2013/191823
Abstract: Phospholipids play an essential role in cell membrane structure and function. The length and number of double bonds of fatty acids in membrane phospholipids are main determinants of fluidity, transport systems, activity of membrane-bound enzymes, and susceptibility to lipid peroxidation. The fatty acid profile of serum lipids, especially the phospholipids, reflects the fatty acid composition of cell membranes. Moreover, long-chain n-3 polyunsatured fatty acids decrease very-low-density lipoprotein assembly and secretion reducing triacylglycerol production. N-6 and n-3 polyunsatured fatty acids are the precursors of signalling molecules, termed “eicosanoids,” which play an important role in the regulation of inflammation. Eicosanoids derived from n-6 polyunsatured fatty acids have proinflammatory actions, while eicosanoids derived from n-3 polyunsatured fatty acids have anti-inflammatory ones. Previous studies showed that inflammation contributes to both the onset and progression of atherosclerosis: actually, atherosclerosis is predominantly a chronic low-grade inflammatory disease of the vessel wall. Several studies suggested the relationship between long-chain n-3 polyunsaturated fatty acids and inflammation, showing that fatty acids may decrease endothelial activation and affect eicosanoid metabolism. 1. Introduction Cardiovascular disease is the leading cause of mortality in many economically developed nations accounting for about 30% of all deaths [1] and its incidence is still increasing. Ongoing research aims to investigate and prevent the early development of cardiovascular risk factors such as atherosclerosis, hypertension, dyslipidemia, chronic inflammation, and insulin resistance. The beneficial effects of n-3 polyunsaturated fatty acids (n-3 PUFAs) were proved in several observational and experimental studies. The lipid lowering action of n3-PUFAs was detected at the beginning, so these nutrients were used for the treatment of dyslipidemic disorders. Their anti-inflammatory, antithrombotic, antiatherosclerotic, and antiarrhythmogenic effects were observed later. Low-grade chronic inflammation is now recognized as a prominent process in the development of atherosclerosis and coronary heart disease. The induction of inflammation may well provide a link between hyperlipidemia and atherogenesis [2, 3]. Atherosclerosis is now considered a “systemic disease” featured by low-grade arterial inflammatory lesions that can develop through the disease progression [4]. In physiological conditions, endothelial cells synthesize and release adequate amounts
Sistema regionale delle aree protette della fascia fluviale del Po
F. Noce
Aestimum , 1994,
Las estructuras de la investigación en Argentina (universidades, entes, asociaciones, fundaciones) An Overview of Research Infrastructure for Medieval Studies in Argentina (Associations, Institutes, and Universities)
Esteban Noce
Reti Medievali Rivista , 2012, DOI: 10.6092/1593-2214/361
Abstract: El siguiente trabajo tiene como objetivo presentar un cuadro descriptivo respecto de la situación actual de los estudios sobre la Edad Media en la Argentina. A tal fin, se hará inicialmente referencia a los diversos institutos universitarios, entes públicos, asociaciones y fundaciones que, desde una u otra área de las Ciencias Humanas, realizan su contribución al análisis del Medioevo. Especial atención merecerán las actividades y publicaciones desarrolladas por cada uno de ellos. Tras esto, se aludirá a algunas de las dificultades que supone para el ejercicio de la investigación la posición geográfica y académica correspondiente a nuestro país. The work aims to present an outline of the current situation regarding studies on the Middle Ages in Argentina. To this end, reference is made initially to the various academic institutes, public institutions, associations and foundations, in the different areas of the Human Sciences, that give a contribution to the analysis of the Middle Ages; it pays special attention to the activities and publications developed by each of them. After this, the paper connect some of the difficulties for the exercise of research to the academic and geographical position of the country.
Judaísmo e identidad cristiana en el corpus de Cromacio de Aquileya
Noce, Esteban
Sefarad : Revista de Estudios Hebraicos y Sefardíes , 2012,
Abstract: The aim of this paper is to determine the underling motivation for Chromatius of Aquileia’s strongly anti-Judaic rhetoric. After analyzing the existing interpretations and critically reconsidering the testimonies in which they have been based, we suggest that –regardless of the situation of the Jewish minority in Aquileia–, the bishop’s invective against Iudaei was motivated by the intention to provide to the members of the Christian community with a concrete counter model, an example of what was not to be tolerated by the Christian community and a demonstration of the consequences of such behavior, so that the Christian individual might guard against such errors in his own behavior and beliefs. El presente trabajo procura determinar la motivación subyacente al discurso marcadamente antijudaico de Cromacio de Aquileya. Tras analizar las interpretaciones existentes sobre el fenómeno y reconsiderar críticamente los testimonios en que se han basado, se sugiere que –con independencia de cuál fuese la situación de la minoría judía en la propia Aquileya, circunstancia que ignoramos– la invectiva del obispo contra los Iudaei tuvo por intención proveer a los propios miembros de la comunidad cristiana de un contramodelo concreto en el que el individuo, acaso ignorante de las implicaciones de su elección, pudiese encontrar un buen ejemplo de lo que no era tolerado por la comunidad de la que formaba parte y de las consecuencias que aguardaban a quien no ci ese a ello sus conductas y creencias.
Perfil psicológico de atletas paraolímpicos brasileiros
Samulski, Dietmar;Noce, Franco;
Revista Brasileira de Medicina do Esporte , 2002, DOI: 10.1590/S1517-86922002000400005
Abstract: the purpose of this study was to present and discuss the results of a psychological evaluation carried out with 64 athletes from eight different sports disciplines. the evaluation was carried out in the paralympic training centers in rio de janeiro, s?o paulo, and recife, applying personality tests, motivation tests, stress inventory, and psychometric tests (perception, concentration and reaction time). significant differences were detected in some psychological parameters comparing male and female athletes and athletes with different kinds of disability (physical, visual or mental). in general, the most important motives to begin a sports activity were pleasure and the need for rehabilitation. the main motive for actual sports practice was competition and the desire to overcome limits. the majority of the athletes mentioned the following stressing factors: sleeping problems, pressure to win, and interpersonal conflicts. most of the athletes showed good results in perception and reaction time. based on these results individual guidance was developed to prepare the athletes for the paralympic games.
Does Salvaging the Environment Require Economic Growth
Anthony A. Noce
Journal of Sustainable Development , 2011, DOI: 10.5539/jsd.v4n5p3
Abstract: We examine the determinants of environmental quality by using carbon dioxide emission levels as a proxy for environmental degradation. Our confirmatory, but different approach to analyzing EKC patterns in the data yield results that do not always agree with those found in the literature, which itself has no conclusive answer as to whether an EKC exists. We find that a log-linear form best models variations in carbon dioxide levels for each of the years 1970 and 2007 for the given cross-section of countries. We also note from the cross-sectional regressions that, in 1970, environmental degradation followed a linear trajectory given increasing income levels, but analysis of 2007 data reveals that an N-shaped environmental hypothesis of two inflection points is supported. The panel analysis uncovers similar results including a positive relationship between HDI and environmental degradation; thus leading one to argue that as countries become wealthier, the rate of environmental degradation no longer remains invariable.
Model Calculation of Electron-Phonon Couplings in a Dimer with a Non-Degenerate Orbital
M. Acquarone,C. Noce
Physics , 1999, DOI: 10.1142/S0217979299003052
Abstract: We evaluate all the electron-phonon couplings derived from the one-body electronic interactions, in both the adiabatic and extreme non-adiabatic limit, for a dimer with a non-degenerate orbital built from atomic wave functions of Gaussian shape. We find largely different values of the coupling parameters in the two cases, as well as different expressions of the corresponding terms in the Hamiltonian.
Distance-depending electron-phonon interactions
Marcello Acquarone,Canio Noce
Physics , 2000,
Abstract: For a dimer with a non-degenerate orbital built from atomic wave functions of Gaussian shape we evaluate all the electron-phonon couplings derived from the one-body and two-body electronic interactions, considering both the adiabatic and extreme non-adiabatic limit. Not only the values of the coupling parameters in the two limits, but also the expressions of the corresponding terms in the Hamiltonian differ. Depending on the distance between the dimer ions, some of the two-body couplings are comparable, or even larger than the one-body ones.
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