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Search Results: 1 - 10 of 347204 matches for " Anna R B Doubeni "
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Self-reported colorectal cancer screening of Medicare beneficiaries in family medicine vs. internal medicine practices in the United States: a cross-sectional study
Angela Y Higgins, Anna R B Doubeni, Karon L Phillips, Adeyinka O Laiyemo, Becky Briesacher, Jennifer Tjia, Chyke A Doubeni
BMC Gastroenterology , 2012, DOI: 10.1186/1471-230x-12-23
Abstract: Nationally representative sample of non-institutionalized beneficiaries who received medical care from FPs or internists in 2006 (using Medicare Current Beneficiary Survey). The main outcome was the percentage of patients screened in 2007. We also examined the percentage of patients offered screening.Patients of FPs, compared to those of internists, were less likely to have received an FOBT kit or undergone home FOBT, even after accounting for patients' characteristics. Compared to internists, FPs' patients were more likely to have heard of colonoscopy, but were less likely to receive a screening colonoscopy recommendation (18% vs. 27%), or undergo a colonoscopy (43% vs. 46%, adjusted odds ratios [AOR], 95% confidence interval [CI]-- 0.65, 0.51-0.81) or any CRC screening (52% vs. 60%, AOR, CI--0.80, 0.68-0.94). Among subgroups examined, higher income beneficiaries receiving care from internists had the highest screening rate (68%), while disabled beneficiaries receiving care from FPs had the lowest screening rate (34%).Patients cared for by FPs had a lower rate of screening compared to those cared for by internists, despite equal or higher levels of awareness; a difference that remained statistically significant after accounting for socioeconomic status and access to healthcare. Both groups of patients remained below the national goal of 70 percent.Screening has been shown to decrease the risk of mortality for colorectal cancer (CRC) [1-4]. Although the use of CRC screening has increased in the US, particularly over the past decade [5,6], for many groups, screening rates are below the Healthy People goal of 70% [7]. Primary care physicians (PCPs) play an important role in the delivery of CRC screening services [6,8-12] by advising, recommending, performing and/or referring patients for screening [13]. It is therefore not surprising that studies have consistently reported a strong association between healthcare provider recommendations for and receipt of CRC screenin
W a ciwo ci enzymatyczne szczepów grzybów potencjalnie chorobotwórczych wyizolowanych z wód Jeziora Charzykowskiego
Piotr Kurnatowski,Anna Rózga,Anna Wójcik,B?a?ej Rózga
Medical Mycology , 2007,
Abstract: Wprowadzenie: Grzyby wydzielaj enzymy hydrolityczne, b d ce jednym z determinantów ich patogenno ci. Cel pracy: Celem pracy by o zbadanie w a ciwo ci enzymatycznych, ocenianych za pomoc testu APIZYM (bioMérieux) i metod Staiba w modyfikacji Rózgi, szczepów grzybów potencjalnie chorobotwórczych wyodr bnionych z wód Jeziora Charzykowskiego. Materia y i metody: Wod do badań pobierano w okresie wymieszania wiosennego, stagnacji letniej oraz wymieszania jesiennego z jeziora, cieków zasilaj cych, a tak e na dop ywie i odp ywie Brdy. Izolowanie grzybów i oznaczanie gatunków przeprowadzano zgodnie z wcze niej opisywan procedur . Aktywno enzymatyczn szczepów oceniano za pomoc testu API ZYM (bioMérieux) oraz wykorzystano zmodyfikowan metod Staiba. Wyniki: Z pobranych prób wody wyizolowano 18 gatunków grzybów z 5 rodzajów: Rhodotorula, Cryptococcus, Candida, Klockera i Trichosporon. Ok. 2/3 wyizolowanych gatunków cechowa o si aktywno ci wszystkich zbadanych hydrolaz, pozosta e - od 7 do 14 enzymów; najwy sz fosfatazy kwa nej (e11) i fosfohydrolazy naftolowej AS-BI (e12). Wszystkie wyizolowane gatunki Candida wykazywa y aktywno enzymatyczn wobec albuminy ludzkiej; zakres zmienno ci strefy proteolizy waha si od 0 do 6,5 mm. Wnioski: 1. Aktywno enzymów hydrolitycznych gatunków grzybów izolowanych z wód Jeziora Charzykowskiego i cieków ró ni si w porównaniu ze szczepami izolowanymi od pacjentów oraz izolowanych z wód Zbiornika Sulejowskiego, co wiadczy o ich szerokich mo liwo ciach przystosowania si do rodowiska. 2. Wyst powanie w jeziorze i ciekach wodnych gatunków Rhodotorula glutinis iR. rubra wiadczy o zachodz cych tam procesach samooczyszczania si wód.
Charge tuning of non-resonant magneto-exciton phonon interactions in graphene
Sebastian Rémi,Bennett B. Goldberg,Anna K. Swan
Physics , 2013, DOI: 10.1103/PhysRevLett.112.056803
Abstract: Far from resonance, the coupling of the G-band phonon to magneto-excitons in single layer graphene displays kinks and splittings versus filling factor that are well described by Pauli blocking and unblocking of inter- and intra- Landau level transitions. We explore the non-resonant electron-phonon coupling by high-magnetic field Raman scattering while electrostatic tuning of the carrier density controls the filling factor. We show qualitative and quantitative agreement between spectra and a linearized model of electron-phonon interactions in magnetic fields. The splitting is caused by dichroism of left and right handed circular polarized light due to lifting of the G-band phonon degeneracy, and the piecewise linear slopes are caused by the linear occupancy of sequential Landau levels versus $\nu$.
What Is the Personal Experience of IBD Patients about Their Anti-TNF-Alpha Therapy?  [PDF]
ágnes Milassin, Mariann Rutka, ágnes Anna Csontos, Pál Miheller, Károly Palatka, Mónika Sz?cs, Zoltán Szepes, Anita Bálint, Renáta Bor, Anna Fábián, Klaudia Farkas, Ferenc Nagy, Tamás Molnár
Health (Health) , 2017, DOI: 10.4236/health.2017.97073
AIM: To evaluate and compare the patients opinion on the two types of anti- TNF-α therapies in a Hungarian cohort of IBD patients. METHODS: This was a prospective, multicentre, questionnaire-based observational study carried out in three Hungarian tertiary centres. From April to September 2014, an anonymous questionnaire was distributed to patients diagnosed with ulcerative colitis (UC) or Crohn’s disease (CD), who have received infliximab (IFX) and/or adalimumab (ADA). The survey focused on the preferences of the two anti-TNF-α therapies on the basis of the efficacy, the administration routes and the side effects. RESULTS: 292 IBD patients, 216 CD, 75 UC and 1 indeterminate colitis patient completed the questionnaire. The mean duration of biological therapy was 1.7 (1 - 7) years. IFX treated patients noticed improvement of symptoms at 4 - 5 weeks while ADA treated patients noticed at 5 - 6 weeks. There was no difference between the patients’ satisfaction regarding the types of anti-TNF-α therapy if they received both. However, subcutaneous administration was preferred by ADA-treated patients previously receiving IFX (p = 0.007) compared to intravenous route and they did not intend to change the mode of therapy (p = 0.040). 90% of the patients, receiving only IFX or ADA were satisfied with their present therapy. The majority of patients (186/292, 63.7%) would not switch therapy. 63 of 291, 22% of the patients reported to have some concern with biological therapy—the majority (32/63, 50.8%) due to fear from side effects. CONCLUSION: Generally, patients preferred and would not change the present anti-TNF-α therapy, however, subcutaneous administration was preferred among those patients who had have experience with both.
Neighborhood Socioeconomic Status and Use of Colonoscopy in an Insured Population – A Retrospective Cohort Study
Chyke A. Doubeni, Guruprasad D. Jambaulikar, Hassan Fouayzi, Scott B. Robinson, Margaret J. Gunter, Terry S. Field, Douglas W. Roblin, Robert H. Fletcher
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0036392
Abstract: Background Low-socioeconomic status (SES) is associated with a higher colorectal cancer (CRC) incidence and mortality. Screening with colonoscopy, the most commonly used test in the US, has been shown to reduce the risk of death from CRC. This study examined if, among insured persons receiving care in integrated healthcare delivery systems, differences exist in colonoscopy use according to neighborhood SES. Methods We assembled a retrospective cohort of 100,566 men and women, 50–74 years old, who had been enrolled in one of three US health plans for ≥1 year on January 1, 2000. Subjects were followed until the date of first colonoscopy, date of disenrollment from the health plan, or December 31, 2007, whichever occurred first. We obtained data on colonoscopy use from administrative records. We defined screening colonoscopy as an examination that was not preceded by gastrointestinal conditions in the prior 6-month period. Neighborhood SES was measured using the percentage of households in each subject's census-tract with an income below 1999 federal poverty levels based on 2000 US census data. Analyses, adjusted for demographics and comorbidity index, were performed using Weibull regression models. Results The average age of the cohort was 60 years and 52.7% were female. During 449,738 person-years of follow-up, fewer subjects in the lowest SES quartile (Q1) compared to the highest quartile (Q4) had any colonoscopy (26.7% vs. 37.1%) or a screening colonoscopy (7.6% vs. 13.3%). In regression analyses, compared to Q4, subjects in Q1 were 16% (adjusted HR = 0.84, 95% CI: 0.80–0.88) less likely to undergo any colonoscopy and 30%(adjusted HR = 0.70, CI: 0.65–0.75) less likely to undergo a screening colonoscopy. Conclusion People in lower-SES neighborhoods are less likely to undergo a colonoscopy, even among insured subjects receiving care in integrated healthcare systems. Removing health insurance barriers alone is unlikely to eliminate disparities in colonoscopy use.
Neighborhood Socioeconomic Deprivation and Mortality: NIH-AARP Diet and Health Study
Jacqueline M. Major,Chyke A. Doubeni,Neal D. Freedman,Yikyung Park,Min Lian,Albert R. Hollenbeck,Arthur Schatzkin,Barry I. Graubard,Rashmi Sinha
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0015538
Abstract: Residing in deprived areas may increase risk of mortality beyond that explained by a person's own SES-related factors and lifestyle. The aim of this study was to examine the relation between neighborhood socioeconomic deprivation and all-cause, cancer- and cardiovascular disease (CVD)-specific mortality for men and women after accounting for education and other important person-level risk factors.
Urovysion? testing can lead to early identification of intravesical therapy failure in patients with high risk non-muscle invasive bladder cancer
Whitson, Jared M.;Berry, Anna B.;Carroll, Peter R.;Konety, Badrinath R.;
International braz j urol , 2009, DOI: 10.1590/S1677-55382009000600005
Abstract: purpose: in this study, we investigated the ability of urovysion? to assess response to intravesical therapy in patients with high risk superficial bladder tumors. materials and methods: we performed a retrospective review of patients undergoing intravesical therapy for high risk superficial bladder tumors. urine specimens were collected for urovysion? analysis before and immediately after a course of intravesical therapy. cytology and cystoscopy were performed six weeks after treatment, using either a positive cytology or visible abnormality on cystoscopy as a prompt for biopsy. the operating characteristics of the urovysion? test were then determined. results: 41 patients were identified in whom 47 cycles of induction and 41 cycles of maintenance intravesical therapy were given during the study period. this yielded a total of 88 treatment and evaluation cycles. median follow-up was 9 months per induction (range 1-21 months) and 13 months per patient (range 1-25 months). a total of 133 urine samples were collected for urovysion? of which 40 were positive. based upon standard clinical evaluation, 41 biopsies were performed which detected 20 recurrences. urovysion? testing performed immediately upon completion of therapy for the 41 patients undergoing biopsy yielded a sensitivity, specificity, and accuracy of 85%, 61%, and 71%. conclusions: the use of urovysion? following intravesical therapy for high-risk superficial bladder tumors helps to identify patients at high risk of refractory or recurrent disease who should undergo immediate biopsy under anesthesia.
How Reliable Is Sex Differentiation From Teeth Measurements
Anna P Joseph,Harish R.K,P K. Rajeesh Mohammed,Vinod Kumar R.B
Oral & Maxillofacial Pathology Journal , 2013,
Abstract: Gender determination of human remains recovered in forensic contexts constitutes an important step in medico-legal examination. The ability of the inert, mineralized structures of teeth to resist post-mortem degradation and to survive deliberate, accidental or natural change has led forensic experts to focus on the teeth as a possible source for valuable forensic data in fragmentary and poorly preserved human remains. Numerous studies show that tooth size standards based on odontometric investigations are population specific and can be used in age and sex determination. This paper reviews the methods of determining sex by odontometrics, tooth proportions and sexual dimorphism.
Tolerowanie wysokich st eń chlorku sodowego i zwi zków biogennych przez szczepy grzybów potencjalnie chorobotwórczych wyizolowanych z wód Zbiornika Sulejowskiego i Jeziora Charzykowskiego
Piotr Kurnatowski,Anna Rózga,B?a?ej Rózga,Piotr Babski
Medical Mycology , 2007,
Abstract: Wprowadzenie: Wyst powanie i liczebno grzybów, tak e grzybów potencjalnie chorobotwórczych dla ludzi i zwierz t, w ekosystemach wodnych mo e by zwi zana ze st eniem osmotycznym wody oraz z obecno ci substancji biogennych. Cechy te mog tak e wynika z ró nic w a ciwo ci wykrywanych grzybów. Cel pracy: Oceniano wybrane w a ciwo ci grzybów z gromad: Ascomycota i Basidiomycota izolowanych z wód Zbiornika Sulejowskiego i Jeziora Charzykowskiego -zdolno tolerowania wysokich st eń chlorku sodu oraz zwi zków biogennych. Materia y i metody: Badano zdolno grzybów do wzrostu na pod o ach zawieraj cych ró ne st enia NaCl (8%, 10%, 12% i 14%), azotanu sodu (st enia azotu azotanowego 0,2%, 0,5%, 0,7%), siarczanu amonowego (st enia azotu amonowego 0,2%, 0,5%, 0,7%) lub fosforanu dwusodo-wego (st enia fosforu fosforanowego 0,1%, 0,2%, 0,3%). Wyniki: Szczepy grzybów z gromady Ascomycota by y mniej wra liwe ni grzyby z gromady Basidiomycota na wzrastaj ce st enia NaCl: 2/3 szczepów z Ascomycota i 2/5 - z Basidiomycota wyizolowanych ze Zbiornika Sulejowskiego nie tolerowa o st enia 14%, wszystkie szczepy obydwu gromad z Jeziora Charzykowskiego nie tolerowa y ju 10% NaCl (Ascomycota) i 12% NaCl (Basidiomycota). Grzyby z wód Zbiornika Sulejowskiego wykazywa y wi ksz , ni wyodr bnione z Jeziora Charzykowskiego, tolerancj na zwi zki biogenne: siarczanu amonowego nie tolerowa o ok. 12% szczepów grzybów z gromady Ascomycota ze Zbiornika Sulejowskiego i ok. 47% -z Jeziora Charzykowskiego; a odpowiednio dla grzybów z gromady Basidiomycota - ok. 8-15% i ok. 79%. Azotanu sodu nie tolerowa o 14-21% (w zale no ci od st enia) szczepów z gromady Ascomycota wyodr bnionych ze Zbiornika Sulejowskiego i ok. 53% (bez wzgl du na st enie) - z Jeziora Charzykowskiego, równie ok. 4/5 szczepów z Basidiomycota z tego jeziora nie tolerowa o azotanu sodu, podobnie jak i fosforanu dwusodowego. Wnioski: 1. Szczepy grzybów wyizolowane z Jeziora Charzykowskiego cechuj si mniejsz zdolno ci tolerowania wzrastaj cych st eń NaCl i wysokich st eń zwi zków biogennych, co mo e by zwi zane z wy szym stopniem czysto ci wód tego jeziora ni Zbiornika Sulejowskiego. 2. Grzyby z gromady Ascomycota s mniej ni z gromady Basidiomycota wra liwe na zbadane zwi zki.
Revista GEINTEC : Gest?o, Inova??o e Tecnologias , 2012,
Abstract: Na indústria de petróleo, a gera o de efluentes é inevitável, destacando a quantidade de águas residuais gerada em todas as etapas do processo de produ o: extra o, transporte e refino. Na extra o, uma quantidade considerável de água é injetada nos po os visando aumentar a press o, além de que em alguns casos já existe uma grande quantidade de água misturada ao próprio óleo.A propor o água/óleo aumenta com a idade do po o atingindo em alguns casos a propor o de mais 90% de água. O descarte desse efluente é prejudicial ao meio ambiente, sendo assim indispensável um tratamento prévio. Para a realiza o da busca de patentes utilizou-se a base de dados do World Intellectual Property Organization (WIPO), do Instituto Nacional de Propriedade Industrial (INPI) e o Escritório Europeu de Patentes (Espacenet). Avaliando o cenário mundial e brasileiro, no que concerne aos documentos de pedidos de patentes, podemos caracterizar a prospec o relativa às técnicas de tratamento de água produzida por estar em constante desenvolvimento.
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