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Search Results: 1 - 10 of 586 matches for " Ani Karapetyan "
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Bright light enhances the efficiency of physical activity in combination with a restrictive diet  [PDF]
Boris B. Pinkhasov, Vera G. Selyatitskaya, Ani R. Karapetyan
Health (Health) , 2014, DOI: 10.4236/health.2014.63030
Abstract: The purpose of this study was to analyze the effectiveness of measures aimed at correcting obesity in women and including bright light exposure during aerobic exercise combined with a restrictive diet. A one-stage, randomized study involved 80 obese women aged 20 to 58 years. The inclusion criterion for selecting participants for this research was the presence of primary alimentary-constitutional obesity with body mass index equal to or higher than 30 kg/m2. All the women were distributed into three groups according to the set of applied treatments. In Group 1, the women were on a restrictive diet; in Group 2, the restrictive diet was accompanied with daily aerobic exercise; in Group 3, women were exposed to bright light during exercise. Before and after the treatment course (3 weeks), body weight, waist and hip circumferences were measured; fat amount was determined by the impedancemetry method; and oxygen consumption was determined by indirect calorimetry. Women in Group 1 had reduced body weight, waist and hip circumferences, fat mass and oxygen consumption. Similar changes were identified in women of Group 2, but weight loss was greater, and the level of oxygen consumption increased as compared to the baseline. In women of Group 3, weight loss and increased oxygen consumption were more pronounced than in those of Group 2. The number of metabolic equivalents (MET) in women of Group 3 increased to nearly 1, which corresponded to the value of this index that reflected the resting metabolic rate in patients with normal body weight. Thus, exposure to bright full-spectrum light increases energy metabolism and enhances the effectiveness of exercises, despite prolonged food restriction, which is one of the mechanisms to improve the efficiency of obesity correction.
Association of Erectile Dysfunction and Hypogonadism with Metabolic Syndrome in Men with Lower Urinary Tract Symptoms of Younger and Older Age Groups  [PDF]
Elena Novikova, Vera Selyatitskaya, Igor Mitrofanov, Boris Pinkhasov, Ani Karapetyan
Advances in Sexual Medicine (ASM) , 2014, DOI: 10.4236/asm.2014.44009
Abstract: The aim of this study was to evaluate the incidence and severity of erectile dysfunction (ED) and hypogonadism in 193 men presenting with lower urinary tract symptoms (LUTSs) in the younger (20 - 39 years old) and older (40 - 60 years old) age groups depending on the presence of metabolic syndrome (MetS). Triglycerides, glucose and high-density lipoprotein cholesterol, serum total testosterone (TT), sex hormone-binding globulin, prostate-specific antigen, pituitary hormones levels were measured in serum. Standardized criteria (2009) were used to determine the prevalence of MetS. Patients were assessed based on the International Prostate Symptom Score (IPSS) and the IPSS-Quality of Life (IPSS-QoL) for LUTSs and the International Index of Erectile Function (IIEF) for ED. Hypogonadism was determined in accordance with the ISA, ISSAM, EAU, EAA and ASA recommendations. In men with MetS in the younger age group the incidence of ED was 2.4 times higher, and that of low TT level and hypogonadism was 8.4 times higher compared to men without the syndrome. In the older age group, an increased incidence of ED and low TT level in men with MetS compared to men without the syndrome was on the trend level, but the incidence of hypogonadism was for sure higher (by 1.6 times). In conclusion, the study showed that ED and hypogonadism are associated with MetS by a high degree of certainty in young men with LUTSs. In men of the older age group with LUTSs, the presence of MetS is not so clearly associated with ED and hypogonadism due to the fact that the incidence of these urogenital diseases is also high in men without MetS.
Metabolic syndrome in men and women with upper or lower types of body fat distribution  [PDF]
Boris B. Pinkhasov, Vera G. Selyatitskaya, Ani R. Karapetyan, Elvira L. Astrakhantseva
Health (Health) , 2012, DOI: 10.4236/health.2012.412A200

The purpose of the study was to determine the prevalence of metabolic syndrome as a cluster of risk factors for atherosclerotic cardiovascular disease and type 2 diabetes mellitus and its individual components in groups of men and women with primary obesity having different types of fat distribution. The study involved 142 men and 185 women with primary alimentary-constitutional obesity. The study participants were divided into 2 groups depending on waist-to-hip ratio value. Standardized criteria were used to determine the prevalence of metabolic syndrome and its individual components among the examined men and women. The ratios of the number of participants with lower or upper type of fat distribution in men and women were 28:114 and 84:101, respectively. Hence the frequency of lower type of fat distribution was 19.7% in men and 45.4% in women (p < 0.000). Men with lower type of body fat distribution as compared to upper type were characterized by a lower prevalence of abdominal obesity (1.9 times), hypertriglyceridemia (1.4 times), low HDL-C (1.6 times), and hypertension (2 times). The frequency of metabolic syndrome in men with lower type of fat distribution was lower by 2.7 times than that of men with upper type of fat distribution. Women with lower type of fat distribution as compared to upper type had a lower prevalence of abdominal obesity (1.2 times), hypertriglyceridemia (1.8 times), low HDL-C (1.2-fold), and hypertension (in 1.5 times). The frequency of metabolic syndrome in women with lower type of fat distribution was lower by 1.9 times than that of women with upper type of fat distribution. Both men and women in the groups with lower type of fat distribution were missing such a component of metabolic syndrome as hyperglycemia i.e. they had the minimal risk of type 2 diabetes mellitus.

Plato & Dukor on Philosophy of Sports, Physical Education and African Philosophy: The Role of Virtue and Value in Maintaining Body, Soul and Societal Development  [PDF]
Ani Casimir
Open Journal of Philosophy (OJPP) , 2013, DOI: 10.4236/ojpp.2013.31A038

To the question,“what is sports”, or what is a good sports activity or event, I am sure Plato would know what to say, using references to his philosophical division of man into three parts, namely: the appetite soul; the emotional soul and the reasonable soul. Plato would have said that sports comes from the human person and being, and so, for any particular sports to be accorded the accolade of goodness it must have the correspondence of the three constituent parts of man’s true nature. The concept of the soul in Plato is what exploring just as that of Professor Maduabuchi Dukor’s expositions concerning the African philosophical concepts of soul, mind, spirit and body as they affect philosophy of sports and the discipline of physical education. The article will therefore analyze the link between Plato concept of the good sports, Professor Dukor’s ontological ideas about the African core values as they affect the balance, harmony and health both the mind and body of the human being. The central point here is the analytical framework of enquiry which Plato sustained in his Dialogues when he queries people:“what is this?”. By this he wants people to appreciate the fact that when they are in search of truth, they usually have the impression that they have all when, actually, they have only half-baked understanding of issues. It is important therefore to understand the issues involved in the disciplines of physical education, philosophy of sports, ethics and the ontological frame of African philosophy as profiled under Professor Dukor theistic humanism of African philosophy. Centrally, the dialectical link between Plato and Dukor will expose the ethical dimension to sports development since every thing is not wining and money or drugs should not be the ultimate motivation for sports and physical exercises. The exercise of sports should lead to the dual development and balance of both mind and body; the highest being the competition of the soul with itself and not with others in which laurels, gold or money is won or lost. The man who wins is the one, like in the communal spirit of the African ontology, who has conquered over his selfishness and sacrifices for the good of the community.

The Concept of Feminist Justice in African Philosophy: A Critical Exposition of Dukor’s Propositions on African Cultural Values  [PDF]
Ani Casimir
Open Journal of Philosophy (OJPP) , 2013, DOI: 10.4236/ojpp.2013.31A030

Having taken note of, and critically analyzed, Professor Maduabuchi Dukor’s epochal work entitled“Theistic Humanism of African philosophy-the great debate on substance and method of philosophy”(2010), I am much encouraged and rationally convinced that he has succeeded in building the core critical and essential foundational pillars of what can safely pass for professional African philosophy, though much remains to be done by way of further research from other scholars. Based upon that conviction and the great prospects that the African philosophy project breakthrough holds for every African philosopher in the global village, I am also motivated to take a closer look at, and carry out a critical exposition of the concept of justice in the context of African cultural values, using the propositions of what he calls the canons of cultural values that are native to African philosophy. These cultural values define African identity and delineateAfrica’s contributions to the advancement of the global ideas of justice, axiology, gender and globalization. The essence and methodology of this article, therefore, will lift the relevant thematic thrusts and arguments made by the erudite Professor of African philosophy to“properly locate African philosophy in the context of globalism, cosmopolitanism, science and what it could contribute to emerging global culture”(Dukor,2010:p.ix). The central point of this critical exposition is that his theistic inspired cultural humanism has enhanced the global understanding of not only justice but feminist rights and the urgent needs for African philosophy to make its contributions towards the emancipation of and empowerment of women both in the continent and globally. The feminist search for justice, according to Dukor, is“the current global pool where the African is needed urgently to intervene”, since“feminism and women liberation has truncated the equilibrium and balance of relations between man and woman. African contribution to this class struggle between man and woman is a neutral one that absorbs the man and woman to their respective natural places in the nature’s womb”. Women’s search for global justice and the struggle to have their human rights recognized as a part of mankind’s gender balancing process would be philosophically enriched by Professor Dukor’s cultural value propositions and canons of justice.

Weighted Anisotropic Integral Representations of Holomorphic Functions in the Unit Ball of
Arman Karapetyan
Abstract and Applied Analysis , 2010, DOI: 10.1155/2010/354961
Abstract: We obtain weighted integral representations for spaces of functions holomorphic in the unit ball and belonging to area-integrable weighted -classes with “anisotropic” weight function of the type , . The corresponding kernels of these representations are estimated, written in an integral form, and even written out in an explicit form (for ). 1. Introduction Denote by the unit ball in the complex -dimensional space . For and , denote by the space of all functions holomorphic in and satisfying the condition where is the Lebesgue measure in . Further, for a complex number with , put We have the following theorem. Theorem 1.1. Assume that , and that the complex number satisfies the condition Then each function admits the following integral representations: where is the Hermitean inner product in . For , that is, for the case of the unit disc , this theorem was established in [1, 2], where the formulas (1.4) are important in the theory of factorization of meromorphic functions in the unit disc. For , the theorem was proved in [3] (when ) and in [4, 5] (when ). In monographs [6, 7], one can find numerous applications of the formulas (1.4) in the complex analysis. In the present paper, we generalize Theorem 1.1 in the following way. Assume that and satisfies the conditions Then we introduce the spaces of functions holomorphic in and satisfying the condition Section 3 contains detailed investigation of these spaces with “anisotropic” weight function. For these “anisotropic” spaces, similarities of the integral representations (1.4) are obtained, but this time a special kernels (where , are associated with , and in a special way) appear instead of (Theorem 4.7). Theorem 4.5 gives the description (in a multiple series form) and the main properties of these kernels. Theorem 4.8 makes it possible to represent the kernels as integrals taken over . Finally, in the special case we write out these kernels in an explicit form (see Theorem 4.12). 2. Preliminaries In this section, we present several well-known facts which will be used in what follows. Fact 1. For and , put then Moreover, if and , then Remark 2.1. Assume that and is a continuous positive (i.e., ) function in . If , then when the corresponding integral exists. Fact 2. For , Fact 3. If , then Fact 4. If , then As a consequence of Stirling’s Formula, we have the following fact. Fact 5. For arbitrary and for In addition, if , and , then Fact 6. Assume that , and ; then is a nondecreasing function of , that is, Corollary 2.2. Assume that , and is a continuous positive (i.e., ) function in . Then if and . In
Design, Evaluation and Analysis of Combinatorial Optimization Heuristic Algorithms
Daniel Karapetyan
Mathematics , 2012,
Abstract: Combinatorial optimization is widely applied in a number of areas nowadays. Unfortunately, many combinatorial optimization problems are NP-hard which usually means that they are unsolvable in practice. However, it is often unnecessary to have an exact solution. In this case one may use heuristic approach to obtain a near-optimal solution in some reasonable time. We focus on two combinatorial optimization problems, namely the Generalized Traveling Salesman Problem and the Multidimensional Assignment Problem. The first problem is an important generalization of the Traveling Salesman Problem; the second one is a generalization of the Assignment Problem for an arbitrary number of dimensions. Both problems are NP-hard and have hosts of applications. In this work, we discuss different aspects of heuristics design and evaluation. A broad spectrum of related subjects, covered in this research, includes test bed generation and analysis, implementation and performance issues, local search neighborhoods and efficient exploration algorithms, metaheuristics design and population sizing in memetic algorithm. The most important results are obtained in the areas of local search and memetic algorithms for the considered problems. In both cases we have significantly advanced the existing knowledge on the local search neighborhoods and algorithms by systematizing and improving the previous results. We have proposed a number of efficient heuristics which dominate the existing algorithms in a wide range of time/quality requirements. Several new approaches, introduced in our memetic algorithms, make them the state-of-the-art metaheuristics for the corresponding problems. Population sizing is one of the most promising among these approaches; it is expected to be applicable to virtually any memetic algorithm.
H?lder Continuity of the Data to Solution Map for HR in the Weak Topology
David Karapetyan
Mathematics , 2011,
Abstract: It is shown that the data to solution map for the hyperelastic rod equation is H\"older continuous from bounded sets of Sobolev spaces with exponent $s > 3/2$ measured in a weaker Sobolev norm with index $r < s$ in both the periodic and non-periodic cases. The proof is based on energy estimates coupled with a delicate commutator estimate and multiplier estimate.
Spectrophotometric Data in Human Immunodeficiency Virus (HIV)-Antiretroviral Drug Coated Blood Interactions  [PDF]
Okwuchukwu Ani, Adaeze Ani, Jeremiah Chukwuneke
Journal of Biosciences and Medicines (JBM) , 2015, DOI: 10.4236/jbm.2015.38005
Abstract: The spectrophotometric data in the interactions between the Human immunodeficiency virus (HIV) and blood cells treated with antiretroviral drug were collected to be used to show the effects of antiretroviral drugs on the absorbance characteristics of HIV infected and uninfected blood. The methodology involved the serial dilution of the five different antiretroviral drugs (two HAART/FDC and three single drugs) and the subsequent incubation with the blood samples collected from ten HIV infected persons who had not yet commenced treatment with the antiretroviral drugs, ten HIV infected persons who had already commenced treatment with the antiretroviral drugs, and ten HIV negative persons, for the absorbance measurements using a digital Ultraviolet Visible MetaSpecAE1405031Pro Spectrophotometer. The peak absorbance data for various interacting systems were measured. These were used to show that the antiretroviral drug had the effect of increasing the peak absorbance values of both the uninfected and infected blood components, i.e., the drugs were made able to increase the light absorption capacity of the blood cells. The use of the findings of this work in drug design may be expected to yield good results.
Destruction of an advanced malignant tumour by direct electrical current-case report  [PDF]
Chima Oji, John Ani
Health (Health) , 2010, DOI: 10.4236/health.2010.29154
Abstract: We carried out a study on the effect of low-level direct current on cancer by using it to treat a woman who had a large malignant squamous cell carcinoma of the sinus cavity. We used a device that produced low-level direct current and passed the current through the tumour via a 4 × 4 cm flat aluminium foil and a needle electrode that was insulated along its entire length except for the portion actually inserted into the tumour. The treatment was eight hourly daily and lasted for eight weeks. The therapy resulted in the total remission of the tumour and a feeling of wellness by the patient. This finding implies promising therapeutic potential for the use of direct electrical current as a simple, effective, low cost alternative for the treatment of cancer.
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