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Search Results: 1 - 10 of 125096 matches for " Angela Wang "
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Vascular and Valvular Calcification in Chronic Peritoneal Dialysis Patients
Angela Yee-Moon Wang
International Journal of Nephrology , 2011, DOI: 10.4061/2011/198045
Abstract: Cardiovascular disease accounts over half of the total mortality in peritoneal dialysis (PD) patients. In addition, there is an increasing recognition of a high prevalence of vascular and valvular calcification that may contribute to the increased all-cause and cardiovascular mortality in the PD patients. Disturbed mineral metabolism in association with chronic kidney disease has been suggested as one of the major contributing factors to the increased vascular/valvular calcification in this population. In this paper, we provide an overview of the prevalence and importance of this complication in the PD patients. In addition, we review the contributing factors and some emerging mechanisms for this complication. Furthermore, we discuss some therapeutic strategies that may be useful in limiting the progression of vascular/valvular calcification in the PD population. 1. Introduction Cardiovascular disease is the leading cause of death in end-stage renal disease (ESRD) patients receiving long-term peritoneal dialysis (PD) therapy. Data from the Canada and United States (CANUSA) Peritoneal Dialysis Study showed that nearly half of the mortality in PD patients was due to cardiovascular disease [1]. According to data from the United State Renal Data System (USRDS), this trend has remained more or less the same in the recent years [2]. Vascular/valvular calcifications are important and highly prevalent complications in ESRD patients including those receiving PD therapy and very much contributed to the exceedingly high cardiovascular mortality in this population. Numerous observational cohort studies demonstrated the prognostic importance of vascular/valvular calcification in ESRD patients. Using plain radiographs to estimate number of arterial sites with calcification including carotid artery, abdominal aorta, and iliofemoral axis, both the presence and extent of vascular calcifications are strong predictors of cardiovascular and all-cause mortality in the ESRD patients [3]. Abdominal aortic calcification detected nonquantitatively using plain lateral abdominal radiographs has also been shown to be an independent predictor of all-cause mortality and cardiovascular death in hemodialysis patients [4]. Using multislice computed tomography (MSCT) that enables quantification of calcification, Block et al. demonstrated a significant mortality effect of the severity of coronary artery calcium score in incident hemodialysis patients [5]. Cardiac valvular calcification, detected using echocardiography, also predicts all-cause mortality and cardiovascular death in chronic
Optical Methods in Orientation of High-Purity Germanium Crystal  [PDF]
Guojian Wang, Yongchen Sun, Yutong Guan, Dongming Mei, Gang Yang, Angela Alanson Chiller, Bruce Gray
Journal of Crystallization Process and Technology (JCPT) , 2013, DOI: 10.4236/jcpt.2013.32009
Abstract:

Two optical methods, namely crystal facet reflection and etching pits reflection, were used to orient <100> and <111> high-purity germanium crystals. The X-ray diffraction patterns of three slices that were cut from the oriented <100> and <111> crystals were measured by X-ray diffraction. The experimental errors of crystal facet reflection method and etching pits reflection method are in the range of 0.05° - 0.12°. The crystal facet reflection method and etching pits reflection method are extremely simple and cheap and their accuracies are acceptable for characterizing high purity detector-grade germanium crystals.

Women entrepreneurship in Romania
Angela ON
Revista Romana de Economie , 2011,
Abstract: Considering entrepreneurship the domain with the greatest potential for creativity and innovation, any investigation on this field is recommended, in order to reveal new aspects that can influence the small enterprises development. From this point of view, female entrepreneurship represents an important source of innovation, only partially exploited or even forgotten.
Remote sensing in inventory of high altitude pastures of the eastern Tibetan Plateau
Timo Kumpula,Alfred Colpaert,Wang Qian,Angela Manderscheid
Rangifer , 2004,
Abstract: The animal husbandry practised on high altitude pastures of the eastern Tibetan Plateau is based on the use of natural pastures. The livestock consists of yaks, sheep and horses. During the recent decades the number of animals has increased in the Dzoge study area, which is located in the north western part of the Sichuan province at an altitude of 2800-4000 meters. Most of Dzoge is treeless grassland with large peat land areas. The remote sensing and Geographical Information System (GIS) methods combined with the conventional pasture mapping provide a methodology to make a cost effective and reliable inventory of large areas. Providing accurate data about the quality and quantity of pastures and also of the amount of natural forage resources promotes sustainable use of the pastures. Two field trips were made to Dzoge. Random test plots (186) covering the main vegetation types in the research area were selected. The Landsat TM image is the remote sensing data in used this study. The image classification was done in the ERMapper program. The final map producing and the accuracy assessment were performed in the ArcGIS program. The Landsat TM image proved to be a useful data source in the mapping of pastures in the Dzoge area. The main vegetation classes were classified accurately. The estimations of the biomass of different vegetation types were made. Elevation differences were relatively small and the shadows on the slopes did not affect the classification significantly.
The Phosphorus and the Vascular Calcification in ESRD between Old Adventures and New Horizons
Biagio Raffaele Di Iorio,Markus Ketteler,Domenico Russo,Angela Wang
International Journal of Nephrology , 2011, DOI: 10.4061/2011/716526
Abstract:
A Viral Infection Model with a Nonlinear Infection Rate
Yumei Yu,Juan J. Nieto,Angela Torres,Kaifa Wang
Boundary Value Problems , 2009, DOI: 10.1155/2009/958016
Abstract: A viral infection model with a nonlinear infection rate is constructed based on empirical evidences. Qualitative analysis shows that there is a degenerate singular infection equilibrium. Furthermore, bifurcation of cusp-type with codimension two (i.e., Bogdanov-Takens bifurcation) is confirmed under appropriate conditions. As a result, the rich dynamical behaviors indicate that the model can display an Allee effect and fluctuation effect, which are important for making strategies for controlling the invasion of virus.
A Viral Infection Model with a Nonlinear Infection Rate
Yu Yumei,Nieto JuanJ,Torres Angela,Wang Kaifa
Boundary Value Problems , 2009,
Abstract: A viral infection model with a nonlinear infection rate is constructed based on empirical evidences. Qualitative analysis shows that there is a degenerate singular infection equilibrium. Furthermore, bifurcation of cusp-type with codimension two (i.e., Bogdanov-Takens bifurcation) is confirmed under appropriate conditions. As a result, the rich dynamical behaviors indicate that the model can display an Allee effect and fluctuation effect, which are important for making strategies for controlling the invasion of virus.
The Phosphorus and the Vascular Calcification in ESRD between Old Adventures and New Horizons
Biagio Raffaele Di Iorio,Markus Ketteler,Domenico Russo,Angela Wang
International Journal of Nephrology , 2011, DOI: 10.4061/2011/716526
Abstract:
Systemic Treatments for Noninfectious Vitreous Inflammation
Angela Jiang,Jillian Wang,Malav Joshi,John Byron Christoforidis
Mediators of Inflammation , 2013, DOI: 10.1155/2013/515312
Abstract: Vitreous inflammation, or vitritis, may result from many causes, including both infectious and noninfectious, including rheumatologic and autoimmune processes. Vitritis is commonly vision threatening and has serious sequelae. Treatment is frequently challenging, but, today, there are multiple methods of systemic treatment for vitritis. These categories include corticosteroids, antimetabolites, alkylating agents, T-cell inhibitors/calcineurin inhibitors, and biologic agents. These treatment categories were reviewed last year, but, even over the course of just a year, many therapies have made progress, as we have learned more about their indications and efficacy. We discuss here discoveries made over the past year on both existing and new drugs, as well as reviewing mechanisms of action, clinical dosages, specific conditions that are treated, adverse effects, and usual course of treatment for each class of therapy. 1. Introduction Vitreous inflammation, or vitritis, may result from many causes, including both infectious and noninfectious. Epidemiologic studies indicate that uveitis accounts for 2–10% of prevalent blindness in the European and North American population and is therefore an underrated and significant public health problem [1]. Infectious etiologies include bacterial Lyme, syphilis, or Bartonella; viruses HSV, VZV, and CMV, and a variety of fungal and parasitic causes. Noninfectious etiologies include rheumatologic and autoimmune processes, examples being sarcoidosis, systemic lupus erythematosus, multiple sclerosis, and Behcet’s disease. However, idiopathic vitritis without associated systemic disease is most common. Vitritis is sometimes visionthreatening, due to sequelae such as cystoid macular edema (CME), vitreous opacities, and retinal detachment, ischemia/neovascularization, or pigment epithelium changes. Glaucoma and cataracts may also form. With such serious sequelae, there are multiple methods of systemic treatment for vitritis. On the other hand, mild vitritis without vasculitis or CME can sometimes be followed closely without any treatment. The goal of all types of treatment is to rapidly alter and stop the course of intraocular inflammation but at the same time minimize any side effects from these systemic drugs. We reviewed these treatment categories last year, but, even over the course of just a year, many therapies have made progress, as we have learned more about their indications and efficacy [2]. 2. Initial Treatment: Corticosteroids The first line of treatment for noninfectious uveitis is corticosteroids. This group of
A Needs-Based Rheumatologist Education Program on Treating to Target in Psoriatic Arthritis and Spondyloarthropathy: Insights and Challenges  [PDF]
Janet Pope, Linda Wang, Paul Tingey, Angela Montgomery, Art Karasik, Pauline Boulos, Vandana Ahluwalia, Maggie Larche, Sara Haig, Nikhil Chopra, Gina Rohekar, Sherry Rohekar
Open Journal of Rheumatology and Autoimmune Diseases (OJRA) , 2017, DOI: 10.4236/ojra.2017.71005
Abstract: Objectives: To determine if comparative practice data and education for rheumatologists would change physician behavior for monitoring and treating psoriatic arthritis (PsA) and spondyloarthritis (SpA). Methods: Participating rheumatologists each performed a chart audit on 20 patients with PsA and SpA. Accredited education (determined by a survey and chart audits) and results of chart audits (comparing to other rheumatologists) were provided for each participant (intervention). Eight months later, a repeat chart audit by each participant was conducted on another 20 PsA and SpA patients. Changes in measurements collected, treatment given and patient characteristics pre and post intervention were analyzed. Results: Nine rheumatologists received the intervention. At baseline, most routinely monitored PsA and SpA for clinical and laboratory markers. In PsA, there was no change post-intervention in performing SJC (96%), TJC (91%), ESR (70%), CRP (73%), and CDAI (25%). In SpA, there were increased measurements of inflammatory markers (54% pre vs. 61% post for CRP), more NSAID use and decreased physical exam measures and HAQ but no significant changes. There were no major treatment differences pre and post intervention including NSAIDs, DMARDs and biologics. Conclusions: The rheumatologists frequently performed measurements of disease activity, did not change significantly with educational intervention so there may have been little room for improvement and many patients were already in a low disease state. Calculation of composite scores did not increase in PsA. The validity of physical exam and BASDAI as a measurement of disease activity were noted as concerns in applying a treat-to-target approach in SpA. Significance and Innovation: This study did not show a significant change in behavior for rheumatologists who had education based on care gaps and needs assessment in psoriatic arthritis and spondyloarthropathy. The rheumatologists identified that disease activity is difficult to determine with usual care in SpA and thought some measures lacked validity.
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