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Search Results: 1 - 10 of 157915 matches for " André K. Samandoulougou "
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Use of Vasopressive Amines in a Limited Resource Country  [PDF]
Anna Thiam, Lidwine Alakoua, Géorges Kinda, Aimé Bama, Larissa Kagambéga, Géorges Millogo, Jonas Kologo, Nvalentin Yaméogo, André K. Samandoulougou, Patrice Zabsonré
Open Access Library Journal (OALib Journal) , 2017, DOI: 10.4236/oalib.1104064
Introduction: Vasopressive amines are frequently used in cardioology. The aim of our work was to evaluate the practical modalities of use of amines in the cardiology department of University Hospital Yalgado Ouédraogo. Patients and Methods: We conducted a prospective observational study for 6 months, from 01 June to 31 November 2013, including all patients treated with vasopressive amines. We were interested in the different clinical pictures, the indications, the choice of amines, and the practical application of the treatment. Results: Fifty patients were included in the study; the mean age was 58 ± 17.6. The sex ratio was 0.85. Hypertensive heart disease was the underlying cardiac disease in 34% of cases. A known chronic heart failure was observed in 62% of cases. Clinical admission tables were dominated by overall heart failure (74%). Vascular collapse (38%) and shock (36%) were the main indications of treatment. Severe alterations in left ventricular systolic function were found in 74% of cases. Dobutamine was the amine of choice (90%). The average time to start treatment was 96.32 minutes (range 15-660 minutes). The time to relay between syringes was more than ten minutes in 72% of the cases, and the nurses’ unavailability was the main cause. Monitoring was manual in almost all cases. The average duration of treatment was 6.64 days. Treatment-related incidents were observed in 26% of cases. The intra-hospital mortality of patients with amines was 48%. Conclusion: The indications of vasopressive amines in the cardiology department are close to the international recommendations. But this treatment suffers in its practical application. The duration of treatment remains excessive but is explained by the lack of therapeutic alternative.
Management Problems of Trans-Frontier Yellow Fever Cases in Burkina Faso 2010  [PDF]
Seydou Yaro, Aline R. Ouoba, Alidou Zango, Jérémi Rouamba, Aly Drabo, Soumeya Ouangraoua, Fati Samandoulougou-Kirakoya, Jean Macq, Annie Robert, Jean Bosco Ouedraogo
Advances in Infectious Diseases (AID) , 2013, DOI: 10.4236/aid.2013.32013

This last decade, Burkina Faso has been confronted with yellow fever confirmed cases, mainly from Western part of the country. In 2010, National Reference laboratory of yellow fever received 970 sera of suspected cases from the 65 Health Districts of the country. We found 11 positive results by ELISA test researching specific IgM against yellow fever. An aliquot of these eleven positive sera were sent to Dakar for confirmation by sero neutralization and RT-PCR. Eight have been confirmed by regional laboratory of Pasteur Institute of Dakar and three were classified as doubtful. Confirmed cases were manly notified by Sindou (4/8) and Mangodara (3/8) Health Districts and the last one came from Nongr-masson health District situated in the central part of the country. Three out of the four confirmed cases in Sindou Health District were resident from neighboring village in Ivory Cost. Conformed cases coming from neighboring villages of Ivory Cost were difficult to manage because of the relative lack of coordination between the two health centers responsible in two different countries. The three cases were not notified to Ivory Cost Health authorities and, in addition, they didn’t benefit from the Burkina Faso response plan. The goal of this work is to present results from National Reference yellow fever laboratory in 2010 in Burkina Faso and stressing trans-frontier cases management problems in order to suggest a multinational mechanism of response to fight against this disease more effectively.

Andrés Filnkeilsteiln K
Revista de Otorrinolaringología y Cirugía de Cabeza y Cuello , 2009,
The baseline pressure of intracranial pressure (ICP) sensors can be altered by electrostatic discharges
Per K Eide, André Bakken
BioMedical Engineering OnLine , 2011, DOI: 10.1186/1475-925x-10-75
Abstract: We performed bench-testing of a set of commercial ICP sensors. In our experimental setup, the ICP sensor was placed in a container with 0.9% NaCl solution. A test person was charged 0.5 - 10 kV, and then delivered ESD's to the sensor by touching a metal rod that was located in the container. The continuous pressure signals were recorded continuously before/after the ESD's, and the pressure readings were stored digitally using a computerized systemA total of 57 sensors were tested, including 25 Codman ICP sensors and 32 Raumedic sensors. When charging the test person in the range 0.5-10 kV, typically ESD's in the range 0.5 - 5 kV peak pulse were delivered to the ICP sensor. Alterations in baseline pressure ≥ 2 mmHg was seen in 24 of 25 (96%) Codman sensors and in 17 of 32 (53%) Raumedic sensors. Lasting changes in baseline pressure > 10 mmHg that in the clinical setting would affect patient management, were seen frequently for both sensor types. The changes in baseline pressure were either characterized by sudden shifts or gradual drifts in baseline pressure.The baseline pressures of commercial solid ICP sensors can be altered by ESD's at discharge magnitudes that are clinically relevant. Shifts in baseline pressure change the ICP levels visualised to the physician on the monitor screen, and thereby reveal wrong ICP values, which likely represent a severe risk to the patient.In patients with brain injury due to traumatic brain injury, stroke, or complications to neurosurgery, the continuous monitoring of intracranial pressure (ICP) is crucial for surveillance [1-3], even though no randomized trials have confirmed the benefit of ICP monitoring in patients with brain injury [4].Modern ICP monitoring was first introduced by Janny in 1950 [5] and Lundberg in 1960 [6]. While ICP initially was mostly measured from fluid-filled catheters in connection with the ventricular cerebrospinal fluid (CSF), the first ICP micro transducers were introduced in the 1980's [7,8]. The ICP
Differences in the quality of interpersonal care in complementary and conventional medicine
André Busato, Beat Künzi
BMC Complementary and Alternative Medicine , 2010, DOI: 10.1186/1472-6882-10-63
Abstract: A comparative observational study in Swiss primary care with written survey completed by patients who visited a GP one month earlier. 6133 patients older than 16 years of 170 certified CAM physicians, of 77 non-certified CAM physicians and of 71 conventional physicians were included. Patients completed a questionnaire aimed at symptom relief, patient satisfaction, fulfilment of expectations, and quality of patient-physician interaction (EUROPEP questionnaire).CAM physicians treated significantly more patients with chronic conditions than COM physicians. CAM Patients had significant higher healing expectations than COM patients. General patient satisfaction was significantly higher in CAM patients, although patient-reported symptom relief was significantly poorer. The quality of patient-physician communication was rated significantly better in CAM patients.The study shows better patient-reported outcomes of CAM in comparison to COM in Swiss primary care, which is related to higher patient satisfaction due to better patient-physician communication of CAM physicians. More effective communication patterns of these physicians may play an important role in allowing patients to maintain more positive outcome expectations. The findings should promote formative efforts in conventional primary care to improve communication skills in order to reach the same levels of favourable patient outcomes.The trend that patients seek more and more help in complementary and alternative medicine (CAM) is a phenomenon in almost all western healthcare systems. CAM therapies that are used instead of conventional medicine are termed "alternative." CAM therapies used alongside conventional medicine are said to be "complementary." With reference to this merging of CAM with conventional biomedicine (COM) an increasing number of clinicians and researchers uses the term "integrative" medicine. However, it is argued that combination medicine (CAM added to COM) is not integrative as such. Integrative
Primary care physician supply and other key determinants of health care utilisation: the case of Switzerland
André Busato, Beat Künzi
BMC Health Services Research , 2008, DOI: 10.1186/1472-6963-8-8
Abstract: The data were derived from the complete claims data of Swiss health insurers for 2004 and included 21.4 million consultations provided by 6564 Swiss primary care physicians on a fee-for-service basis. Socio-demographic data were obtained from the Swiss Federal Statistical Office. Utilisation-based health service areas were created and were used as observational units for statistical procedures. Multivariate and hierarchical models were applied to analyze the data.Models within the study allowed the definition of 1018 primary care service areas with a median population of 3754 and an average per capita consultation rate of 2.95 per year. Statistical models yielded significant effects for various geographical, socio-demographic and cultural factors. The regional density of physicians in independent practice was also significantly associated with annual consultation rates and indicated an associated increase 0.10 for each additional primary care physician in a population of 10,000 inhabitants. Considerable differences across Swiss language regions were observed with reference to the supply of ambulatory health resources provided either by primary care physicians, specialists, or hospital-based ambulatory care.The study documents a large small-area variation in utilisation and provision of health care resources in Switzerland. Effects of physician density appeared to be strongly related to Swiss language regions and may be rooted in the different cultural backgrounds of the served populations.Previous research on variations in the volume of physician services in geographic areas has emphasized that an additional use of services is not necessarily associated with improved health in the corresponding populations[1]. After controlling for input prices and health status, it was found that the volume of physician services is driven partly by local practice patterns and partly by differences in physician density and speciality. However, an association between greater volume a
Performance of Nanofiltration (NF) and Low Pressure Reverse Osmosis (LPRO) Membranes in the Removal of Fluorine and Salinity from Brackish Drinking Water  [PDF]
Courfia K. Diawara, Saidou N. Diop, Mouhamadou A. Diallo, Michel Farcy, André Deratani
Journal of Water Resource and Protection (JWARP) , 2011, DOI: 10.4236/jwarp.2011.312101
Abstract: Certain areas in Senegal have a serious problem of high fluoride and salinity in underground water because of soil properties. This water currently used for drink has a bad taste on consumption and caused diseases like dental fluorosis and skeletal fluorosis. A membrane filtration plant constructed by Pall Corporation was improved through nanofiltration (NF) and Low Pressure Reverse Osmosis (LPRO). Both NF and LPRO membranes were shown applicable for salinity and fluoride ions removal from brackish and high fluorinated drinking water in a remote community. The NF membrane has given a fluorine retention rate varying between 63.3% and 71% while the LPRO membrane allow to reach 97 to 98.9% for fluorine rejection. Highest salinity rejection rates expressed through conductivity measurements are around 46% and 97% for respectively NF and LPRO.
T Cell Mediated Antibody lnvariance in an Immune Response Against A Bacterial Carbohydrate Antigen Requires CD28/B7–1 Costimulation
André Rademaekers,Eckehart K lsch,Christoph Specht
Clinical and Developmental Immunology , 2001, DOI: 10.1155/2001/87168
Abstract: The humoral immune response against α(1→3) dextran (Dex) in BALB/c mice is characterized by the formation of predominantly IgM antibodies bearing the J558 idiotype. IgG antibodies do not appear in euthymic mice. In athymic animals however, the response proceeds to a vigorous IgG production. In euthymic mice formation of IgG is suppressed by J558 idiotype- specific regulatory T cells recognizing in association with I-Ed and in cognate T/B interaction the VH CDR3 derived peptide of the J558 idiotpye. Only B-2 lymphocytes produce IgG whereas B-1 cells do not participate in the production of this Ig class. Using a novel synthetic all α(1→3)-D-gluco configurated tetrasaccharide the Dex-specific B cells can for the first time be analyzed in FACS. In experiments using this newly designed low molecular Dex no signs of B cell apoptosis can be found. This demonstrates a true silencing of persisting Bγ memory cells and supports previous by adoptive transfer experiments. In this suppression an involvement of CD28/B7–1 interaction can be demonstrated which is a necessary costimulatory suppression signal in addition to the cognate TCR/peptide-I-Ed interaction between J558 Id-specific T cells and J558 idiotype beating B cells. This results in an activation of 178–4 Ts cells, leading to an overall suppression of the Dex-specific IgG isotype production on the one hand and on the other hand provides a signal for the survival and clonal expansion of J558 Id-positive B cells.
A Survey on Security in Mobile Peer-to-Peer Architectures—Overlay-Based vs. Underlay-Based Approaches
Christian Gottron,André K?nig,Ralf Steinmetz
Future Internet , 2010, DOI: 10.3390/fi2040505
Abstract: Mobile Ad hoc networks (MANET) and Peer-to-Peer (P2P) networks share central characteristics such as their distributed and decentralized nature. Combining both networking paradigms results in a Mobile Peer-to-Peer (MP2P) system that operates independently from a preexisting infrastructure. Securing MP2P networks in terms of availability and robustness as basic demands in envisioned application scenarios like first responder operations is a challenging task. In this article, we present a survey of selected threats and of state of the art countermeasures for MANETs and P2P networks. Further, we discuss the efficiency of MANET and P2P security mechanisms when applied in MP2P networks.
Factors related to treatment intensity in Swiss primary care
André Busato, Pius Matter, Beat Künzi
BMC Health Services Research , 2009, DOI: 10.1186/1472-6963-9-49
Abstract: The study was designed as a cross-sectional investigation, based on the complete claims data from all Swiss health care insurers for the year 2004, which covered information from 6087 primary care physicians and 4.7 million patients. Utilization-based health service areas were constructed and used as spatial units to analyze effects of density of supply. Hierarchical linear models were applied to analyze the data.The data showed that, within a service area, a higher density of primary care physicians was associated with higher mortality rates and specialist density but not with treatment intensity in primary care. Higher specialist density was weakly associated with higher mortality rates and with higher treatment intensity density of primary care physicians. Annual physician-level data indicate a disproportionate increase of supplied services irrespective of the size of the number of patients treated during the same year and, even in high volume practices, no rationing but a paradoxical inducement of consultations occurred. The results provide empirical evidence that higher densities of primary care physicians, specialists and the availability of out-patient hospital clinics in a given area are associated with higher volume of supplied services per patient in primary care practices.Analyses stratified by language regions showed differences that emphasize the effect of the cantonal based (fragmented) governance of Swiss health care.The study shows high volumes in Swiss primary care and provides evidence that the volume of supply is not driven by medical needs alone. Effects related to the competition for patients between primary care physicians, specialists and out-patient hospital clinics and an association with the system of reimbursing services on a fee-for-service basis can not be excluded.Swiss health care is based on the principles of universal health care, granting access to a broad range of services and, to a large extent, the financial protection is achieve
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