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Search Results: 1 - 10 of 70544 matches for " Ana Paula do Rego André "
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Profile of Patients Treated in Outpatient Vestibular Rehabilitation at a Hospital in São Paulo  [PDF]
Bárbara Vieira Coró, Miguel Angelo Hyppolito, Camila Giacomo Carneiro Barros, Ana Paula do Rego André
International Journal of Clinical Medicine (IJCM) , 2019, DOI: 10.4236/ijcm.2019.101002
Abstract: Introduction: Currently it is very common that the search for diagnosis and treatment for curing diseases can cause vertigo or dizziness. Objective: This study sought to characterize the profile of patients seen in the clinic for vestibular rehabilitation in a tertiary hospital in the last 10 years. Methods: Survey questionnaires of patients with dizziness. Results: The prevalence of treated subjects was female 65.3% (N = 439). The average age was 54.9 years old. Dizziness type roundabout was more prevalent 33.04% (N = 222). Tinnitus occurred in 58.33% of the population. The time of most observed dizziness was less than 5 years 70.68% (N = 475). Neurovegetative symptoms appeared in 63.98% (N = 430) of the population. The bilateral normal hearing was more standard 35.26% (N = 237). The topographic diagnosis of peripheral origin was the most usual 65.47% (N = 440). Conclusion: The peripheral otoneurologic involvement was more prevalent in this population, affecting more women at an average age of 54.9 years old. The most prevalent symptoms were vertigo, nausea, tachycardia, sweating, vomiting and tinnitus, characterizing the peripheral vestibular impairment. The time of dizziness was less than five years. Audiological standard normal curve was predominant and the symptom of tinnitus was the most reported. The most prevalent comorbidity was Hypertension.
Long-Term Efficacy of Repositioning Maneuvers in Benign Paroxysmal Positional Vertigo  [PDF]
Erika Barioni Mantello, Ana Paula do Rego André, Nathali Singaretti Moreno, Miguel ?ngelo Hyppolito, Julio Cesar Moriguti
International Journal of Clinical Medicine (IJCM) , 2011, DOI: 10.4236/ijcm.2011.22029
Abstract: To determine the characteristics of 12 patients with a diagnosis of benign paroxysmal positional vertigo (BPPV) treated by the repositioning maneuver during a 24-month follow-up period after the initial discharge a longitudinal clinical study was performed in which a questionnaire for the assessment of discomfort caused by dizziness was applied at the first visit, at the last visit after treatment and 2 years after the initial discharge. Repositioning treatment was again offered to patients who suffered relapses. In 10 cases (83.34%) there was no recurrence of symptoms and 2 patients (16.66%) presented symptoms exactly 2 years after the original discharge showing that treatment of BPPV by repositioning manuevers is effective in the long term, but new studies in larger populations are needed to determine the pattern of the rates of recurrence of BPPV.
Number of maneuvers need to get a negative Dix-Hallpike test
Moreno, Nathali Singaretti;André, Ana Paula do Rego;
Brazilian Journal of Otorhinolaryngology , 2009, DOI: 10.1590/S1808-86942009000500006
Abstract: benign paroxysmal positional vertigo is one of the most common causes of dizziness. its characteristic clinical profile is dizziness at head movements. the main diagnostic maneuver of posterior canal benign paroxysmal positional vertigo is the dix-hallpike test. if the maneuver is positive (vertigo and/or nystagmus), the physician can perform the epley maneuver on the injured side. aim: this paper aims at checking the number of maneuvers necessary for patients with posterior canal benign paroxysmal positional vertigo to have a negative dix-hallpike test. materials and methods: we carried out a retrospective analysis of 71 charts of patients with posterior canal benign paroxysmal positional vertigo, who were treated with the modified epley maneuver. study design: cross-sectional retrospective. results: we found that 76.00% of the patients analyzed had the symptoms completely resolved and negative dix-hallpike test with a single maneuver. conclusion: based on our results it is possible to conclude that the number of modified epley maneuvers is variable depending on the etiology, being that the benign paroxysmal positional vertigo secondary to the traumatic brain injury needed a greater number of maneuvers for dix-hallpike test to become negative.
Características audiológicas de idosos com Vertigem Posicional Paroxística Benigna
Moreno, Nathali Singaretti;André, Ana Paula do Rego;
Revista Brasileira de Otorrinolaringologia , 2009, DOI: 10.1590/S0034-72992009000200023
Abstract: benign paroxysmal positional vertigo (bppv) is one of the most common causes of dizziness; it constitutes the most common vestibular disorder in the elderly with vertigo. its characteristic clinical aspect is dizziness at head movement, with not hearing alteration. aim: this paper aims at studying the audiologic characteristics of elderly with bppv of the posterior semicircular canal. materials and methods: we carried out a retrospective analysis of threshold tonal audiometry exams of 37 senior citizens with posterior semicircular canal bppv and also of 37 elderly without complaints of dizziness and/or vertigo, and we studied the audiologic characteristics of the two groups. results: both groups had high rates of hearing loss, especially the descending curve sensorineural type, and there was no statistically significant difference between the groups. conclusion: having such data, we can conclude that posterior semicircular canal bppv has no impact on the hearing loss features of senior citizens; nonetheless, because of the spontaneous degeneration of the vestibulocochlear system, such population has a prevalence of hearing loss.
Condutas pós-manobra de Epley em idosos com VPPB de canal posterior
André, Ana Paula do Rego;Moriguti, Julio Cesar;Moreno, Nathali Singaretti;
Brazilian Journal of Otorhinolaryngology , 2010, DOI: 10.1590/S1808-86942010000300005
Abstract: benign paroxysmal positional vertigo is the most common peripheral vestibular disorder, especially in the elderly and presents as the predominant etiology in this population of the degeneration of the utricular macula. aim: to compare the effectiveness of the approaches after epley maneuver. study design: longitudinal cohort. materials and methods: the study included 53 volunteers with benign paroxysmal positional vertigo of the posterior semicircular canal, divided into group 1, who underwent epley maneuver associated with the use of neck collar and post-maneuver instructions, group 2 underwent the epley maneuver without the use cervical collar and/or post-maneuver restrictions, and group 3 underwent the epley maneuver associated with the use of a mini vibrator, without the use of neck collar and/or post-maneuver restrictions. results: in the three groups, the number of epley maneuvers ranged from one to three. we employed the brazilian dizziness handicap inventory - pre-and post-treatment and observed a statistically significant difference on most scores pre-and post-treatment for both groups. conclusion: regardless of the post epley maneuver treatment selected for the treatment of benign paroxysmal positional vertigo, it was effective when comparing the brazilian dizziness handicap inventory pre-and post-treatment.
Avalia??o de combina??es de técnicas alternativas de constru??o e montagem de blocos de tissue microarray
Santos Junior, Ivan Tiburtino dos;Rego, André Ricardo Benites Cavalcanti;Sobral, Ana Paula Veras;
Jornal Brasileiro de Patologia e Medicina Laboratorial , 2010, DOI: 10.1590/S1676-24442010000100009
Abstract: introduction and objectives: the aim of this study was to investigate different alternative tissue microarray (tma) techniques and to make adaptations, combining different tissue punch and tma block construction techniques in order to introduce easily reproducible, operational and cost effective tma techniques in the oral pathology laboratory of pernambuco college of dentistry, state university of pernambuco. methods: four donor punch techniques and two tma block construction techniques were performed, resulting in a total of eight possible combinations. for each combination three tma blocks were made, containing 9, 16 and 32 samples, respectively. they were evaluated as to sample loss, cost effectiveness, construction time and difficulty. results: for blocks with 9 samples, combination 2 was the most appropriate; for blocks with 16, combination 6 was the most efficient; and for blocks with 32, combination 1 was the most cost effective. conclusion: it was concluded that the combination choice depends on the number of samples to be put in tma blocks.
Microsatellites and the Polyploid Guarana Plant: Diversity under a Sea of Alleles  [PDF]
Paula Cristina da Silva Angelo, Maria do Perpétuo Socorro Lira, Manuella Villar Amado, Ana Takagaki Yamaguishi, Gilvan Ferreira Silva, Jorge Ivan Rebelo Porto, Spartaco Astofi-Filho, André Luiz Atroch
Open Journal of Genetics (OJGen) , 2014, DOI: 10.4236/ojgen.2014.43020
Abstract:

Repeat blocks, microsatellites or simple sequence repeats (SSRs) can produce good co-dominant molecular markers for genetic diversity analysis and the determination of self-pollination rates in progenies originating from open pollination of selected genotypes. The enrichment of guarana genomic libraries was underway when it was confirmed that we are working with a complex polyploid species with 210 chromosomes. The probes (CA)12, (CT)12 and (TC)14 were used to finish the enrichment of four libraries for repeat blocks and the screening of a databank of expressed sequence tags (ESTs) from guarana seeded-fruits was accomplished as well. Fifteen clonal cultivars were genotyped with three replicas at 10 out of 27 identified loci using the 59 alleles that passed the reproducibility criterion. A large number of short repeat blocks were identified and this was considered to be a consequence of the recent polyploidization event. However, blocks with eight or more repeats ideal for genotyping were scarce. Annealing of most probes to short blocks by partial complementarity could explain the scarcity of longer blocks in genomic libraries but cannot explain why they were rare in the ESTs. Due to the complexity of the genotypes, alleles were treated as dominant traits. ESTs harboring repeat blocks had the functional annotation renewed. Locus GRN07 is inserted in a homologue of the MOTHER OF FLOWERING LOCUS T AND TFL1 (MFT), in which 3’-UTR displays clear post-transcriptional regulatory features. MFT and its variants are probably involved in the determination of seed germination and embryo growth characteristics. Other accessed loci can be involved in plant architecture and defense reactions. It was concluded that the

HPV 16 detection in cervical lesions, physical state of viral DNA and changes in p53 gene
Oliveira, Ledy do Horto dos Santos;Rodrigues, Eliane de Vasconcelos Machado;Lopes, Ana Paula Terra Alvim de Salles;Fernandez, André de Paula;Cavalcanti, Silvia Maria Baeta;
Sao Paulo Medical Journal , 2003, DOI: 10.1590/S1516-31802003000200007
Abstract: context: persistent infection with high risk human papillomavirus (hpv) has been linked to cervical carcinoma. integration of viral dna into host cell dna is essential for this cancer development, promoting disruption of the hpv e2 gene, thus leading to unregulated increases in e6 and e7 proteins and inactivating the products of p53 and rb tumor suppressor genes. objective: to investigate hpv 16 infection in cervical lesions, physical state of viral dna and p53 gene alterations in a group of women attending a public health service. design: prospective, non-controlled, transversal study. setting: gynecological clinic of the school od medicine, universidade federal fluminense. sample: 43 consective patients with cervical lesions referred to our service. main measurements: cases were classified via cytology/histology as normal, hpv infection, condyloma, low-grade squamous intraepithelial lesion (lsil), high-grade squamous intraepithelial lesion (hsil) and carcinoma. hpv infection was studied via polymerase chain reaction (pcr) using two pcr primer sets, to determine dna integration. p53 gene changes were investigated by single-strand conformation polymorphism (sscp) analysis. results: one normal case, 7 hpv infections, 6 condylomas, 7 lsil, 14 hsil and 8 cancers were found, with 95% positive for hpv genome when tested using both l1 and e6 primers. hpv 16 was most prevalent (73.1%). hpv 16 dna was integrated within the host genome in 3 lsil. one lsil progressed to hsil by 13 months after first diagnosis. among hpv 16-positive hsil cases, 50% contained integrated viral dna. hpv 16 e2 gene disruption was seen in 7 cancers (87.5%). only smal-cell carcinoma showed intact hpv 16 e2 gene. abnormal p53 bands detected by pcr/sscp were observed in 4 cases: 2 squamous carcinoma with parametrium (exon 8) and two cervical intraepithelial neoplasia (cin) iii (exons 5 and 7). all cases presented hpv 16 e2 gene loss. conclusions: the sample had a high rate of high-risk hpv detected in
Fitossociologia, caracteriza??o sucessional e síndromes de dispers?o da comunidade arbórea de remanescente urbano de Floresta Estacional Semidecidual em Monte Carmelo, Minas Gerais
Prado Júnior, Jamir Afonso do;Lopes, Sérgio de Faria;Schiavini, Ivan;Vale, Vagner Santiago do;Oliveira, Ana Paula de;Gusson, André Eduardo;Dias Neto, Olavo Custódio;Stein, Manuela;
Rodriguésia , 2012, DOI: 10.1590/S2175-78602012000300001
Abstract: urban parks have a strategic importance fot the quality of life in urban centers, contributing to significant environmental and social services. knowledge of forest structure has helped to subsidize the maintenance of these parks. based on the phytosociological analysis of tree species in a semideciduous forest fragment (120 ha), this study assessed the conservation status of this remnant. we sampled all trees with cbh > 15 cm, present in 25 permanent plots (20 × 20 m), and classified the species as to successional groups and dispersal syndromes. we recorded 798 individuals in 98 species belonging to 37 families. early secondary species had the highest values of species richness , density and importance value, followed by late secondary species with the highest dominance, and pioneer species with low representation. regarding the dispersal syndrome, over 77% of the community is represented by species with zoochoric dispersal. these results increase the valuation of the "parque da matinha", reaffirming the importance of this urban park for the conservation of native fauna and flora, and supporting the need for public policies of park use by visitors.
Exercício e restri??o alimentar aumentam o RNAm de proteínas do transito de Ca2+ miocárdico em ratos
Sugizaki, Mário Mateus;Leopoldo, Ana Paula Lima;Conde, Sandro José;Campos, Dijon Salome;Damato, Ricardo;Leopoldo, André Soares;Nascimento, André Ferreira do;Oliveira Júnior, Silvio de Assis;Cicogna, Antonio Carlos;
Arquivos Brasileiros de Cardiologia , 2011, DOI: 10.1590/S0066-782X2011005000066
Abstract: background: chronic exercise and food restriction (fr) have directionally opposite changes in transcription of molecular structures of calcium handling and thyroid hormone (th) status. objective: evaluate the association of chronic exercise and fr on serum thyroid hormones and gene transcription of molecular structures of intracellular calcium transients and thyroid receptors in myocardium of rats. methods: male wistar kyoto rats, divided into two groups: control (c, n = 7), fr (r50, n = 7), chronic exercise (ex, n = 7) and chronic exercise + fr (ex50, n = 7). fr was of 50% and exercise was swimming (1 hour/day, 5 days/week, during 12 weeks). serum concentrations of t3, t4 and tsh were determined. the mrna gene expression of the sarcoplasmatic reticulum calcium pump (serca2a), phospholamban (plb), na+/ca+2 exchanger (ncx), calcium channel l-type (l-channel), ryanodine (ryr), calsequestrin (cqs) and ht receptor (trα1 and trβ1) of the myocardium was performed by pcr real-time. results: fr reduced serum levels of t4 and tsh and trα1 mrna and increased the expression of plb, ncx and l-channel. exercise increased the trβ1 receptor, l-channel and ncx. the association of exercise and fr reduced plasma t4 and tsh, trβ1 mrna increase, serca2a, ncx and plb, and there was a significant correlation of trβ1 with cqs and nxc. conclusion: chronic exercise and food restriction increased the mrna of transient ca2+ proteins; however, th-receptor axis cannot participate in the transcription of mrna of myocardial calcium transient proteins.
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