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Search Results: 1 - 10 of 32965 matches for " Ana Linares "
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Medidas imitanciométricas em crian?as com ausência de emiss?es otoacústicas
Linares, Ana Emilia;Carvallo, Renata Mota Mamede;
Revista Brasileira de Otorrinolaringologia , 2008, DOI: 10.1590/S0034-72992008000300016
Abstract: considering the hypothesis that middle ear changes can impair the recording of otoacoustic emissions, it is possible that absent otoacoustic emissions in infants could be associated with a light tympanometric change. aim: to study the association between transient otoacoustic emissions and changes in acoustic immittance measurements with 226hz probe tone in neonates. methods: cross-sectional contemporary cohort study. 20 infants with no transient otoacoustic emissions (study group) and 101 infants with transient otoacoustic emissions (control group), with ages ranged from birth to eight months, were assessed. infants were submitted to: admittance tympanometry; contralateral acoustic reflex threshold with stimulus of 0.5, 1, 2, 4 khz and broad band noise; transient and distortion product otoacoustic emissions. the auditory brain response was used to study the threshold in neonates without transient otoacoustic emissions. results: significant statistical differences were observed between the groups (p < 0.005), characterized by reduction in tympanometric configuration and increase acoustic reflex thresholds in the study group. these data suggest the occurrence of middle ear mild impairment in infants without transient otoacoustic emissions associated with normal auditory brain response. conclusion: tympanometry associated with acoustic reflex adds accuracy to the diagnosis of middle ear abnormalities.
Fish oil supplementation reverses the effect of cholesterol on apoptotic gene expression in smooth muscle cells
Sonia Perales, Ma Alejandre, Rogelio Morales, Carolina Torres, Ana Linares
Lipids in Health and Disease , 2010, DOI: 10.1186/1476-511x-9-70
Abstract: An in vivo/in vitro cell model was used, culturing SMC isolated from chicks exposed to an atherogenic cholesterol-rich diet with 5% of cholesterol (SMC-Ch) alone or followed by an anti-atherogenic fish oil-rich diet with 10% of menhaden oil (SMC-Ch-FO) and from chicks on standard diet (SMC-C). Cells were exposed to 25-HC, studying apoptosis levels by flow cytometry (Annexin V) and expressions of caspase-3, c-myc, and p53 genes by quantitative real-time reverse transcriptase-polymerase chain reaction. Results: Exposure to 25-HC produced apoptosis in all three SMC cultures, which was mediated by increases in caspase-3, c-myc, and p53 gene expression. Changes were more marked in SMC-Ch than in SMC-C, indicating that dietary cholesterol makes SMC more susceptible to 25-HC-mediated apoptosis. Expression of p53 gene was elevated in SMC-Ch-FO. This supports the proposition that endogenous levels of p53 protect SMC against apoptosis and possibly against the development of atherosclerosis. Fish oil attenuated the increase in c-myc levels observed in SMC-C and SMC-Ch, possibly through its influence on the expression of antioxidant genes.Replacement of a cholesterol-rich diet with a fish oil-rich diet produces some reversal of the cholesterol-induced changes, increasing the resistance of SMC to apoptosis.Gene expression is influenced by dietary fat [1], gene transcription is regulated by dietary polyunsaturated fatty acids [2], and the nutritional control of gene regulation guides the transformation of SMC into foam cells in atherosclerosis [3]. The present study focused on the effect of cholesterol and fish oil intake on the expression of apoptosis-regulating caspase-3, c-myc and p53 genes.In the 1970 s, a very low incidence of death from ischemic heart disease was observed in Greenland Eskimos, who have a high fish consumption [4]. Evidence from several research lines supports the hypothesis that fish consumption may protect against atherosclerotic vascular disease. Fish oil
Escenarios de vulnerabilidad por ascenso del nivel del mar en la costa mexicana del Golfo de México y el Mar Caribe
Mario Arturo Ortiz Pérez,Ana Patricia Méndez Linares
Investigaciones geográficas , 1999,
Abstract: Mediante la caracterización geomorfológica del litoral se identifican áreas vulnerables a las variaciones del nivel del mar. A partir de esta zonificación se estimaron las áreas de impacto por inundación sobre el nivel del mar a 1 y 2 m. Se obtuvo como resultado el mapeo de distribución del fenómeno de impacto, con la utilización de modelos digitales del terreno.
Componentes naturales y de uso del suelo vulnerables a las variaciones del nivel del mar en la costa atlántica de México
Mario Arturo Ortiz Pérez,Ana Patricia Méndez Linares
Investigaciones geográficas , 2000,
Abstract: Con base en el arreglo de la estructura fisiográfica y en la identificación de las características geomorfológicos del perfil longitudinal de la costa. se reconocen dos zonas: a) la de intermareas considerada como el escenario besico de impacto directo en las variaciones del nivel del mar. y b) la franja adyacente perimareal (Supralltoral) que por su disposición constituye un área de amortiguamiento o de riesgo potencial. En ambos escenarios se llevó a cabo un inventario de los componentes naturales y del uso del suelo, con objeto de conocer la distribución de las áreas vulnerables al ascenso del nivel del mar. La identificación de éstos se realizó mediante fotointerpretaci6n w n verificación de campo. Los resultados se procesaron en un sistema de información geográfica
Nanotechnology: An Urgent Need  [PDF]
Francisco M. Marquez Linares
Soft Nanoscience Letters (SNL) , 2013, DOI: 10.4236/snl.2013.33008

From the first forecasts and expectations of nanotechnology, in the late 90s, there are many things that have changed and too many expectations not fulfilled. By 2050, the population is expected to exceed 9 billion people. At that time, or even before, the situation in the world can be very difficult if we do not put all the means at our disposal.

Effect of Oxysterol-Induced Apoptosis of Vascular Smooth Muscle Cells on Experimental Hypercholesterolemia
Sonia Perales,M. José Alejandre,Rogelio Palomino-Morales,Carolina Torres,Jose Iglesias,Ana Linares
Journal of Biomedicine and Biotechnology , 2009, DOI: 10.1155/2009/456208
Abstract: Smooth muscle cells (SMCs) undergo changes related to proliferation and apoptosis in the physiological remodeling of vessels and in diseases such as atherosclerosis and restenosis. Recent studies also have demonstrated the vascular cell proliferation and programmed cell death contribute to changes in vascular architecture in normal development and in disease. The present study was designed to investigate the apoptotic pathways induced by 25-hydroxycholesterol in SMCs cultures, using an in vivo/in vitro cell model in which SMCs were isolated and culture from chicken exposed to an atherogenic cholesterol-rich diet (SMC-Ch) and/or an antiatherogenic fish oil-rich diet (SMC-Ch-FO). Cells were exposed in vitro to 25-hydroxycholesterol to study levels of apoptosis and apoptotic proteins Bcl-2, Bcl-XL and Bax and the expression of bcl-2 and bcl-xL, genes. The quantitative real-time reverse transcriptase-polymerase chain reaction and the Immunoblotting western blot analysis showed that 25-hydroxycholesterol produces apoptosis in SMCs, mediated by a high increase in Bax protein and Bax gene expression. These changes were more marked in SMC-Ch than in SMC-Ch-FO, indicating that dietary cholesterol produces changes in SMCs that make them more susceptible to 25-hydroxycholesterol-mediated apoptosis. Our results suggest that the replacement of a cholesterol-rich diet with a fish oil-rich diet produces some reversal of cholesterol-induced changes in the apoptotic pathways induced by 25-hydroxycholesterol in SMCs cultures, making SMCs more resistant to apoptosis.
Adverse events and readmissions after day-case urological surgery
Paez, Alvaro;Redondo, Enrique;Linares, Ana;Rios, Emilio;Vallejo, Jorge;Sanchez-Castilla, Margarita;
International braz j urol , 2007, DOI: 10.1590/S1677-55382007000300005
Abstract: objective: the literature lacks of studies on postoperative outcomes after urological ambulatory surgery. our study aims to identify parameters associated with postoperative complications within 30 days after ambulatory urological surgery. materials and methods: adjusted and unadjusted comparisons between clinical features and postoperative outcome (complicated and uncomplicated). results: postoperative course was complicated in 5% of the patients. discharge schedule was not completed in 1.1% while unplanned visits resulted in admission in 0.5%. multivariate analyses could only confirm the independent effect of type of anesthesia and diagnosis-related group (drg) relative weight. conclusions: ambulatory urological surgery can be safe in terms of postoperative complications. in the present study surgery under general anesthesia, or a higher drg relative weight procedure, increased the risk of complications compared to surgery under regional or local anesthesia or lower drg relative weight operations. patients scheduled for general anesthesia or undergoing complex urological procedures should be warned about an increased risk of postoperative incidents and/or readmission.
Revista Colombiana de Antropología , 2012,
Abstract: the genetic structure of the population of antioquia is complex and arises from the historical admixture of european, african and amerindian populations. the genetic makeup of 849 antioquian individuals was determined using a set of 75 ancestry informative markers and four computer programs based on bayesian methods in order to infer the composition of ancestral admixture. a great european component (60%) was twice as high as the amerindian contribution (28%), both with broad distributions, followed by a smaller african contribution (12%). the average number of generations since the admixture event was 11 generations per 100 cm, which makes this population a useful resource to implement admixture mapping studies. the usefulness of the marker set as well as the power and helpfulness of the computer programs were assessed.
Potencial evocado auditivo de estado estável em audiologia pediátrica
Linares, Ana Emilia;Costa Filho, Orozimbo Alves;Martinez, Maria Angelina Nardi de Souza;
Brazilian Journal of Otorhinolaryngology , 2010, DOI: 10.1590/S1808-86942010000600010
Abstract: the main issue regarding pediatric audiology diagnosis is determining procedures to configure reliable results which can be used to predict frequency-specific hearing thresholds. aim: to investigate the correlation between auditory steady-state response (assr) with other tests in children with sensorineural hearing loss. methods: prospective cross-sectional contemporary cohort study. twenty-three children (ages 1 to 7; mean, 3 years old) were submitted to assr, behavioral audiometry, click audiometry brain stem response (abr), tone burst abr, and predicting hearing level from the acoustic reflex. results: the correlation between behavioral thresholds and assr was (0.70- 0.93), for the abr tone burst it was (0.73 -0.93), for the abr click it was (0.83-0.89) only at 2k and 4 khz. the match between the assr and the hearing threshold prediction rule was considered moderate. conclusion: there was a significant correlation between the assr and audiometry, as well as between abr click (2k and 4 khz) and for the abr tone burst. the acoustic reflex can be used to add information to diagnosis in children.
Especie nueva de Albizia (Leguminosae: Mimosoideae) de Centroamérica
Linares, José;
Revista mexicana de biodiversidad , 2005,
Abstract: a new species, albizia xerophytica sp. nov., is described and illustrated, and its taxonomic affinities are discussed. the tree has been collected from the low-land broadleaf forests of el salvador, honduras and nicaragua of northern central america.
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