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Search Results: 1 - 10 of 331117 matches for " Ana Lúcia O.;Bosignoli "
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Tireotoxicose por triiodotironina e sua variante: relato de três casos
Machado, Marise;Teixeira, Rosimere J.;Le?o, Lenora Maria C.S.M.;Tabet, Ana Lúcia O.;Bosignoli, Rogério;Henriques, Jodélia L.M.;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2003, DOI: 10.1590/S0004-27302003000100016
Abstract: thyrotoxicosis is confirmed by high serum total or free triiodothyronine (t3/ft3) and thyroxine (t4/ft4) and low serum thyrotropin (tsh) concentrations. in endemic areas, a predominant increase of t3 with normal or low t4 and ft4 can be found, referred to as "t3-thyrotoxicosis". one variant, known as "free t3-toxicosis" has recently been described presenting subnormal serum tsh, normal ft4 and total t3 concentrations, but high serum ft3. thyrotoxicosis increases bone turnover, especially resorption, with bone loss and increases fracture rates; involves the cardiovascular system both in systemic hemodynamics and t3-mediated effects on cardiac myocite-specific gene expression. detecting t3- thyrotoxicosis is important because of the high morbidity, increased risk of osteoporosis and arrythmias. thus, the early diagnosis and treatment of the hyperthyroidism can prevent complications. we studied three patients with criteria for t3-toxicosis - one of them with ft3 toxicosis. they live in areas with adequate iodine intake and all three present with diffuse goiter. because the screening for thyroid diseases only measures ft4 and tsh, we suggest that patients with subnormal tsh levels and normal ft4 should be worked up with measurement of total t3. if normal, a ft3 can be obtained to identify ft3 toxicosis. the study of such cases must continue to provide valuable insights into the thyrotoxicosis.
Potential of Penicillium Species in the Bioremediation Field
Ana Lúcia Leit?o
International Journal of Environmental Research and Public Health , 2009, DOI: 10.3390/ijerph6041393
Abstract: The effects on the environment of pollution, particularly that caused by various industrial activities, have been responsible for the accelerated fluxes of organic and inorganic matter in the ecosphere. Xenobiotics such as phenol, phenolic compounds, polycyclic aromatic hydrocarbons (PAHs), and heavy metals, even at low concentrations, can be toxic to humans and other forms of life. Many of the remediation technologies currently being used for contaminated soil and water involve not only physical and chemical treatment, but also biological processes, where microbial activity is the responsible for pollutant removal and/or recovery. Fungi are present in aquatic sediments, terrestrial habitats and water surfaces and play a significant part in natural remediation of metal and aromatic compounds. Fungi also have advantages over bacteria since fungal hyphae can penetrate contaminated soil, reaching not only heavy metals but also xenobiotic compounds. Despite of the abundance of such fungi in wastes, penicillia in particular have received little attention in bioremediation and biodegradation studies. Additionally, several studies conducted with different strains of imperfecti fungi, Penicillium spp. have demonstrated their ability to degrade different xenobiotic compounds with low co-substrate requirements, and could be potentially interesting for the development of economically feasible processes for pollutant transformation.
Colegiado gestor: uma análise das possibilidades de autogest?o em um hospital público
Abrah?o,Ana Lúcia;
Ciência & Saúde Coletiva , 2008, DOI: 10.1590/S1413-81232008000100014
Abstract: this paper analyzes the possibilities for self-management through an administration committee in a public hospital in s?o paulo state, examining this experience and identifying the collective arrangements established from the standpoint of self-managed areas. this analysis focuses on the production dynamics of subjective aspects that pass by the administration committee of the hospital under examination, using the daily records of the institution and simple observation as the research methods. charting the committee processes indicated the establishment of collective activities guided by models based on shared management experiences, where the introduction of processes assigning joint responsibility can promote a management style with room for the dynamics of singularization. this paper also comments on some elements constituting self-management movements that are apparent in the conflict triggered by hetero-management processes.
Educa??o profissional e gest?o em saúde: pressupostos teórico-conceituais na forma??o de profissionais de nível médio
Silva, Ana Lúcia Abrah?o da;
Trabalho, Educa??o e Saúde , 2005, DOI: 10.1590/S1981-77462005000200006
Abstract: this article discusses the theoretical and conceptual premises that serve as guidelines for the program of the joaquim venancio polytechnic health school course on professional education on administration of health services. the article simultaneously describes how the administration of health services was assembled, seeking to identify the knowledge required of technicians in administration of health services, and debates the configuration that was designed for professional education since the promulgation of the lei de diretrizes e bases da educa??o (education guidelines and principles act), of 1996. in the end, the article proposes the creation of a sequential course comprised of crossing axes which seek to train independent professionals that comply with the proposed changes, especially those regarding decentralization, regionalization and democratization in health administration.
Student’s Academic Efficacy or Inefficacy? An Example on How to Evaluate the Psychometric Properties of a Measuring Instrument and Evaluate the Effects of Item Wording  [PDF]
Jo?o Maroco, Ana Lúcia Maroco, Juliana Alvares Duarte Bonini Campos
Open Journal of Statistics (OJS) , 2014, DOI: 10.4236/ojs.2014.46046

This study evaluated the effect of item inversion on the construct validity and reliability of psychometric scales and proposed a theoretical framework for the evaluation of the psychometric properties of data gathered with psychometric instruments. To this propose, we used the Maslach Burnout Inventory, which is the most used psychometric inventory to measure burnout in different professional context (Students, Teachers, Police, Doctors, Nurses, etc…). The version of the MBI used was the MBI-Student Survey (MBI-SS). This inventory is composed of three key dimensions: Exhaustion, Cynicism and Professional Efficacy. The two first dimensions—which have positive formulated items—are moderate to strong positive correlated, and show moderate to strong negative correlations with the 3rd dimension—which has negative formulated items. We tested the hypothesis that, in college students, formulating the 3rd dimension of burnout as Inefficacy (reverting the negatively worded items in the Efficacy dimension) improves the correlation of the 3rd dimension with the other two dimensions, improves its internal consistency, and the overall MBI-SS’ construct validity and reliability. Confirmatory factor analysis results, estimated by Maximum Likelihood, revealed adequate factorial fit for both forms of the MBI-SS (with Efficacy) vs. the MBI-SSi (with Inefficacy). Also both forms showed adequate convergent and discriminant related validity. However, reliability and convergent validity were higher for the MBI-SSi. There were also stronger (positive) correlations between the 3 factors in MBI-SSi than the ones observed in MBI-SS. Results show that positively rewording of the 3rd dimension of the MBI-SS improves its validity and reliability. We therefore propose that the 3rd dimension of the MBI-SS should be named Professional Inefficacy and its items should be positively worded.

Agente Comunitário de Saúde: um novo ator no cenário da saúde do Brasil
Filgueiras, Andréa Sabino;Silva, Ana Lúcia Abrah?o;
Physis: Revista de Saúde Coletiva , 2011, DOI: 10.1590/S0103-73312011000300008
Abstract: the community health agents program (pacs) was created in 1991 as a strategy to implement the sus, developing activities related to prevention and health education. in 1994, the health ministry proposed the family health program (psf) as a strategy for restructuring the dominant care model. with the emergence of these two programs, there is the emergence of a new actor in the health scenario, the community health agent (acs). this actor plays an important role in basic care, acting as a link between families, users and health service. this study takes as subject the work of acs in a family health unit in the city of volta redonda, rio de janeiro state. it aims to discuss the facilitators and limiting aspects of the activities assigned to the acs. this is a search-type descriptive work, with qualitative approach. data analysis was made by analytical categories that emerged from data from the interviews. after data analysis, we found that the acs from volta redonda's psf do not receive training to develop their activities and that they consider the experience the main engine to perform activities. teamwork is recognized as a space for scientific knowledge circulation, and popular knowledge as a mediator between team and population. the work acs is centered on home visit, mainly focused on disease.
Equipes gerenciadas por mulheres: representa??es sociais sobre gerenciamento feminino
Mour?o, Tania Maria Fontenele;Galinkin, Ana Lúcia;
Psicologia: Reflex?o e Crítica , 2008, DOI: 10.1590/S0102-79722008000100012
Abstract: the aim of this study was to apprehend the way teams that have a woman as amanager are building the social representation about this management. the participants were 74 women and 72 men whose teams work with seven women who have reached the top of their careers in administrative positions of das 5 and das 6 levels of the public federal administration. a free association test was applied and analyzed through the evoc software. the results showed that the participants identified some characteristics on women management that were considered a feminine form of leadership: interpersonal relationship, respect for individuality, concern with the quality of work. this kind of management carries an interactive style that is characterized by the capacity to promote inclusion, which is a characteristic of flat management nets.
Caminhos para a integralidade na educa??o profissional técnica de nível médio em saúde
Abrah?o, Ana Lúcia;Cassal, Luan Carpes Barros;
Trabalho, Educa??o e Saúde , 2009, DOI: 10.1590/S1981-77462009000200004
Abstract: the objective of this study is to understand and problematize the term 'integral' in professional education and health. this term is related to ways to produce health in the core of the services and in education with total access to the knowledge involved in work and education. in health care, the relationship between the professional, with his techniques and knowledge, and the user with his needs and desire to return to autonomy, is one of the areas that points o the integrality of production in health. it is in this environment that professionals and users have power and autonomy and can cooperate or compete. in the study, we used a literature-based qualitative bibliography. through successive readings of the bibliographic material, we produced an argumentative discussion between different theoretical references in the areas of health and education. in the end, it was possible to identify the different ties that constitute the integrality in health education.
Effect of phenolic compounds and osmotic stress on the expression of penicillin biosynthetic genes from Penicillium chrysogenum var. halophenolicum strain
Sumaya Ferreira Guedes,Ana Lúcia Leit?o
Journal of Xenobiotics , 2012, DOI: 10.4081/xeno.2012.e2
Abstract: Phenol and phenolic compounds are aromatic pollutants that inhibit biological treatment of wastewaters. Penicillium chrysogenum var. halophenolicum is a halotolerant fungus that previously showed the ability to degrade phenol and resorcinol in high salinity conditions. The presence of the penicillin biosynthetic cluster in P. chrysogenum var. halophenolicum was recently described. In this article, we examined the expression of pcbAB, pcbC and penDE, genes responsible for δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase, isopenicillin N synthase and isopenicillin N acyltransferase activities, respectively, in P. chrysogenum var. halophenolicum. A quantitative PCR (qPCR) approach was used to determine how these genes were expressed in media with 2% and 5.9% NaCl supplemented with phenol, catechol, hydroquinone and resorcinol as the sole carbon source. The effect of salt on the capability of P. chrysogenum var. halophenolicum to degrade aromatic compounds was measured using HPLC. qPCR analysis of RNA extracted from P. chrysogenum var. halophenolicum indicated that the expression levels of pcbAB, pcbC and penDE decreased in high saline concentrations compared to the levels expressed in media with glucose. High concentrations of salt significantly repress the expression of pcbAB and penDE. The pcbC gene was expressed differentially in catechol containing medium. There was no evident relationship between the expression levels of penicillin biosynthetic genes and yields of penicillin. Meanwhile, the presence of phenol and phenolic compounds seems to positively influence the antibiotic production; high concentrations of salt stimulated penicillin production. These results support the hypothesis that phenol, phenolic compounds and high concentrations of salt could act like a stress factor for P. chrysogenum var. halophenolicum resulting in higher yields of β-lactam antibiotic production.
Women managers' teams – social representations about feminine management / Equipes gerenciadas por mulheres - representa es sociais sobre gerenciamento feminino
Tania Maria Fontenele Mour?o,Ana Lúcia Galinkin
Psicologia: Reflex?o e Crítica , 2008,
Abstract: The aim of this study was to apprehend the way teams that have a woman as amanager are building the social representation about this management. The participants were 74 women and 72 men whose teams work with seven women who have reached the top of their careers in administrative positions of DAS 5 and DAS 6 levels of the Public Federal Administration. A free association test was applied and analyzed through the EVOC software. The results showed that the participants identified some characteristics on women management that were considered a feminine form of leadership: interpersonal relationship, respect for individuality, concern with the quality of work. This kind of management carries an interactive style that is characterized by the capacity to promote inclusion, which is a characteristic of flat management nets.
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