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Search Results: 1 - 10 of 16488 matches for " Amar Pal Singh "
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HPTLC-MS as a Neoteric Hyphenated Technique for Separation and Forensic Identification of Drugs  [PDF]
Kanak Lata Verma, Manoj Kumar, Amar Pal Singh
Journal of Analytical Sciences, Methods and Instrumentation (JASMI) , 2018, DOI: 10.4236/jasmi.2018.81001
Abstract: Drugs are traditionally been identified on basis of chromatographic-spectroscopic hyphenated techniques in instrumental analysis. Gas chromatography (GC) and Liquid chromatography (LC) hyphenated with mass spectroscopy (MS) i.e. GC-MS and LC-MS give reliable and confirmatory results in drugs identification. In the present work the novel hyphenated technique High Performance Thin Layer Chromatography-Mass Spectroscopy (HPTLC-MS) has been used. This technique provides efficient, quick and simple method for identification and separation of Narcotic drugs and psychotropic substances. The drugs under study are Papaverine, Methadone, Cocaine, Ketamine, Caffeine, Codeine, Diazepam, Thebaine, Heroin, Methamphetamine, Carbamazepine, Morphine, Narcotine and Ephedrine. The present study comprising of sixteen drugs has been carried out on CAMAG HPTLC instrument with automatic sampling. Thin layer chromatography (TLC) plates were developed in various solvent systems, scanned under TLC scanner and the results in terms of Retention Factor (Rf value) and UV spectrum (λmax) are presented in the manuscript. Using hyphenated technique of HPTLC-MS (MS 2020 SHIMADZU) spots of these drugs from TLC plate was lifted with CAMAG TLC-MS interface and confirmed by the mass spectrum of the individual drugs by their m/z values thus delivering fast and accurate confirmatory result on the TLC plate.
Surface Wave Propagation in a Generalized Thermoelastic Material with Voids  [PDF]
Baljeet Singh, Raj Pal
Applied Mathematics (AM) , 2011, DOI: 10.4236/am.2011.25068
Abstract: In the present paper, the propagation of surface wave in a generalized thermoelastic solid with voids is considered. The governing equations are solved to obtain the general solution in x-z plane. The appropriate boundary conditions at an interface between two dissimilar half-spaces are satisfied by appropriate particular solutions to obtain the frequency equation of the surface wave in the medium. Some special cases are also discussed.
Phase diagram of mechanically stretched DNA: The salt effect
Amar Singh,Navin Singh
Physics , 2014, DOI: 10.1016/j.physa.2013.01.029
Abstract: The cations, in form of salt, present in the solution containing DNA play a crucial role in the opening of two strands of DNA. We use a simple non linear model and investigate the role of these cations on the mechanical unzipping of DNA. The Hamiltonian is modified to incoporate the solvent effect and the cations present in the solution. We calculate the melting temperature as well as the critical force that is required to unzip the DNA molecule as a function of salt concentration of the solution. The phase diagrams are found to be in close agreement with the experimental phase diagrams.
Pulling short DNA molecules having defects on different locations
Amar Singh,Navin Singh
Physics , 2015, DOI: 10.1103/PhysRevE.92.032703
Abstract: We present a study on the role of defects on the stability of short DNA molecules. We consider short DNA molecules (16 base pairs) and investigate the thermal as well as mechanical denaturation of these molecules in the presence of defects that occurs anywhere in the molecule. For the investigation, we consider four different kinds of chains. Not only the ratio of AT to GC different in these molecules but also the distributions of AT and GC along the molecule are different. With suitable modifications in the statistical model to show the defect in a pair, we investigate the denaturation of short DNA molecules in thermal as well as constant force ensemble. In the force ensemble, we pulled the DNA molecule from each end (keeping other end free) and observed some interesting features of opening of the molecule in the presence of defects in the molecule. We calculate the probability of opening of the DNA molecule in the constant force ensemble to explain the opening of base pairs and hence the denaturation of molecules in the presence of defects.
Effect of salt concentration on the stability of heterogeneous DNA
Amar Singh,Navin Singh
Physics , 2015, DOI: 10.1016/j.physa.2014.10.029
Abstract: We study the role of cations on the stability of double stranded DNA (dsDNA) molecules.It is known that the two strands of double stranded DNA(dsDNA) have negative charge due to phosphate group. Cations in the form of salt in the solution, act as shielding agents thereby reducing the repulsion between these strands. We study several heterogeneous DNA molecules. We calculate the phase diagrams for DNA molecules in thermal as well as in force ensembles using Peyrard-Bishop-Dauxois (PBD) model. The dissociation and the stacking energies are the two most important factors that play an important role in the DNA stability. With suitable modifications in the model parameters we investigate the role of cation concentration on the stability of different heterogeneous DNA molecules. The objective of this work is to understand how these cations modify the strength of different pairs or bases along the strand. The phase diagram for the force ensemble case (a dsDNA is pulled from an end) is compared with the experimental results.
A New Model for the Etching Characteristics of Corners Formed by Si{111} Planes on Si{110} Wafer Surface  [PDF]
Prem Pal, Sajal Sagar Singh
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.511A001

The etching characteristics of concave and convex corners formed in a microstructure by the intersection of {111} planes in wet anisotropic etchant are exactly opposite to each other. The convex corners are severely attacked by anisotropic Fetchant, while the concave corners remain unaffected. In this paper, we present a new model which explains the root cause of the initiation and advancement of undercutting phenomenon at convex corners and its absence at concave corners on {110} silicon wafers. This contrary etching characteristics of convex and concave corners is explained by utilizing the role of dangling bond in etching process and the etching behavior of the tangent plane at the convex corner. The silicon atoms at the convex edge/ridge belong to a high etch rate tangent plane as compared to {111} sidewalls, which leads to the initiation of undercutting at the convex corner. On the other hand, all the bonds of silicon atoms pertaining to concave edges/ridge are engaged with neighboring atoms and consequently contain no dangling bond, thus resulting in no-undercutting at concave edges/corners.

A Study of Determinants of Sensorineural Hearing Loss in Chronic Suppurative Otitis Media with or without Cholesteatoma  [PDF]
Rajwant Kaur, Satinder Pal Singh, Jagdeepak Singh
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2018, DOI: 10.4236/ijohns.2018.74018
Abstract: Aim: This study was carried out to assess association between Sensorineural hearing loss (SNHL) and Chronic Suppurative Otitis Media (CSOM), to identify possible risk factors and determine correlation of duration of CSOM and incidence of SNHL. Material and Method: The study consisted of 100 patients of either sex between 15 and 40 years of age, suffering from unilateral CSOM for the past three months or more, the normal ear served as control. Results: This study showed duration of symptoms is 18% patients for 5 - 10 years and below 5 years in 73% patients. It was found that mean BC thresholds were significantly higher in the diseased ears as compared to the control ears. Though the higher frequencies are more affected than the lower frequencies, in subtotal and attic perforations the speech frequencies seemed to be maximally affected. Conclusion: CSOM should be diagnosed early and should be managed effectively so as to prevent the chances of developing SNHL.
Indian Streams Research Journal , 2012,
Abstract: The purpose of the study is to highlight the issues related to hospitality industry especially in the wake of increased quantity of waste generation from this industry by identifying the various gaps present in current waste management system in hospitality industry. Study aims to highlight various areas of improvement and their positive implications. For this purpose extensive literature review has been done on hospitality industry in order to find out innovative waste management practices that have the potential to ensure the sustainability of the overall business especially in the context of hospitality sector. Qualitative approach along with various case studies has been used for the carrying out the study. Various parameters and dimensions emerged after analyzing literatures and case studies have been included in concluding remarks of the research paper that help to redefine the hierarchy of waste management currently used in hospitality industry
A Survey on k-Means Clustering Algorithm Using Different Ranking Methods in Data Mining
Amar Singh,Navjot Kaur?
International Journal of Computer Science and Mobile Computing , 2013,
Abstract: As the volume of information on the internet is increasing day by day so there is a challenge forwebsite owner to provide proper and relevant information to the internet. So it is the duty of the serviceprovider to provide the relevant and good information to the internet user when they submit query to thesearch engine. To support the user to move in the result list various ranking methods are used. In this paper,we choose Page Ranking Method called Weighted Page Rank Algorithm which is based on the popularity ofthe page by taking the importance of both the inlinks and outlinks of the pages. After that we use time rankalgorithm for improving the weighted page rank score by using the visit time of the web page. So this conceptis very useful to display most valuable pages on the top of the result list.
Glimpses of the Lichen Flora of Achanakmar-Amarkantak Biosphere Reserve in Central India  [PDF]
Achuta Nand Shukla, Krishna Pal Singh
American Journal of Plant Sciences (AJPS) , 2012, DOI: 10.4236/ajps.2012.36084
Abstract: The present paper enumerates an account of the lichen flora in Achanakmar-Amarkantak Biosphere Reserve located in Central India which comprises 78 species belonging to 25 genera under nine families. Of these, twenty two species have been reported for the first time from Central India. All the species are enumerated with their correct original citation, basionyms if any, their places of occurrence in the reserve area, distributional range and exsiccata have been provided.
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