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Search Results: 1 - 10 of 423 matches for " Amadou Touré "
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The Effect of Human Immunodeficiency Virus-1 Infection on Low Birth Weight, Mother to Child HIV Transmission and Infants’ Death in African Area  [PDF]
Traoré Youssouf, Téguété Ibrahima, Dicko Fatoumata Traoré, Bocoum Amadou, Fané Seydou, Traoré Tidiani, Traoré Mamadou Salia, Dao Seydou, Touré Moustapha, Varol Nesrin, Dolo Amadou
Open Journal of Obstetrics and Gynecology (OJOG) , 2019, DOI: 10.4236/ojog.2019.92017
Abstract: Background: It is yet a controversy subject whether low birth weight and infant death are associated to human immunodeficiency virus-1 infection. Objective: To appreciate association between low birth weights, mother to child HIV transmission and infant mortality in HIV-1 infected pregnant women delivering between 2011 and 2016. Materials: We conducted 6 years cohort study in urban Mali. Outcome included preterm delivery, small for gestational age, infant survival status and HIV transmission. Comparison concerned women clinical WHO stage, mother viro-immunological status, and newborn anthropometric parameters. Results: HIV-1 infected women who delivered low birth weight newborn were 20.9% (111/531) versus 16.5% (1910/11.546) in HIV negative patients (p = 0.016). CD4 T cell counts low than 350 T cells count were strongly associated to LBW (p = 0.000; RR = 3.03; 95% CI [1.89 - 3.16]). There is no significant association between ART that was initiated during pregnancy (p = 0.061, RR = 0.02; CI 95% (1.02 - 1.99)) or during delivery (p = 0.571; RR = 1.01; CI 95% (0.10 - 3.02)) and LBW delivery. In multivariate analysis ART regimens containing protease inhibitor (PI) were lone regimens associated with LBW ((p = 0.030; RR = 1.001; 95%
Management of Pheochromocytoma in Dakar: Diagnostic and Therapeutic Advances throughout 16 Cases  [PDF]
Abdoulaye Leye, Nafy Ndiaye, Yakham Mohamed Leye, Amadou Fall Cisse, Ngoné Diaba Diack, Michel Assane Ndour, Ameth Dieng, Daouda Thioub, Baidy Sy Kane, Alex Bahati, Alpha Omar Touré, Cherif Mohamed Dial, Pape Saloum Diop
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2018, DOI: 10.4236/ojemd.2018.81003
Abstract: Introduction: Management of pheochromocytoma faces different challenges leading to misdiagnosis and therapeutic delay in developing countries. The aim of our study was to evaluate the diagnostic and therapeutic features as well as the evolution of our management strategies in hospital setting in recent years in Dakar. Patients and Method: We carried out a retrospective study over 12 years (January 2005 to June 2017), in 4 hospitals in Dakar. We only included patients with established diagnosis of pheochromocytoma upon clinical, biological, radiological and histological arguments. Results: During this period, 16 observations have been collected and were all about female patients. The mean age at the time of diagnosis was 36.81 years. The clinical signs were dominated by hypertension found for 14 patients. At biological examination, hypersecretion catecholamine was found in 13 patients, high urinary metanephrines in 7 patients, high plasmatic metanephrines in 2 patients and raised urinary Vanyl Mandelic Acid (VMA) in 4 patients. Dosage of chromogranin A showed high level for one patient. Abdominal CT scan allowed making the adrenal origin of tumors precise. One patient presented bilateral pheochromocytoma. Before being treated surgically, all patients had had medical preparation. The surgical treatment by median laparotomy consisted of an enucleation of the tumor in 2 patients, and adrenal resection in 11patients.The evolution after surgery was favorable in 12 patients out of 13. One patient died 2 days after surgery by hemodynamic instability. In 2 patients who presented metastases, multidrug therapy with cyclophosphamide, vincristine and dacarbazine was decided after a multidisciplinary meeting, but they died before treatment. Conclusion: Management of pheochromocytomas in developing countries is obviously improving, but the mortality rate remains high. Early diagnosis and perioperative care are to be targeted for better outcome and prognosis of this rare tumor in our areas.
Malaria Transmission Pattern in an Area Selected for Clinical Trials in the Sudanian Area of Senegal (West Africa)
El Hadji Amadou Niang,Aissatou Touré,El Hadji Malick Ngom,Lassana Konaté
Journal of Tropical Medicine , 2013, DOI: 10.1155/2013/907375
Malaria Transmission Pattern in an Area Selected for Clinical Trials in the Sudanian Area of Senegal (West Africa)
El Hadji Amadou Niang,Aissatou Touré,El Hadji Malick Ngom,Lassana Konaté,Ousmane Faye,Mawlouth Diallo,Ibrahima Dia
Journal of Tropical Medicine , 2013, DOI: 10.1155/2013/907375
Abstract: Malaria transmission pattern was studied in 3 villages (Toubanding, Daga Ndoup, and Keur Samba Guèye) situated within an area selected for clinical trials. The study was conducted in the rainy season from July to December 2011. The main objective of this work was to gather baseline data on malaria transmission intensity and other entomological parameters before the advent of clinical trials. Mosquitoes were collected by Human-Landing Collections (HLCs) and by pyrethrum spray catches (PSCs). Five anopheline species were collected, namely, An. arabiensis, An. gambiae, An. funestus, An. pharoensis, and An. rufipes, giving a heterogeneous distribution within the study area. The populations dynamics of the vectors varied temporarily in each village depending on the pattern of the rainy season. Transmission intensity estimated by the entomological inoculation rate (EIR) was measured in each of the three villages with the variations linked to the microecological differences between the villages. Measurements were calculated for August, September, and October and were found to vary between 4 and 30 infected bites per person over the study period with a peak intensity observed in September. These results indicate that epidemiological field trials on malaria could be conducted in this area on the basis of the differences observed with transmission intensity, micro-ecological variations, and the objectives of the trials. 1. Background Malaria continues to be a major public health problem throughout the world despite more than a century of study, especially in Africa where 90% of the global cases are recorded. The situation is worsening due to the spread of drug resistant parasites strains, spread of insecticide resistance in the vector populations, and poor economic status of endemic populations [1]. To alleviate the problem, an integrated approach against both the parasites and vectors for an effective control is necessary. Over the last five years, considerable efforts have been made to control malaria in many countries around the world (especially in Sub-Saharan Africa) using strategic measures with available tools. This has led to the decline in malaria transmission in many parts of Africa [2, 3]. These changes are as a result of an extensive use of long-lasting insecticidal nets (LLINs) and improved malaria diagnosis and treatment. However, despite these significant progresses, malaria remains an acute problem killing 800000 people each year, mostly children under five years living in Sub-Saharan Africa [1]. The situation is particularly worrying with the
Use of Bayesian geostatistical prediction to estimate local variations in Schistosoma haematobium infection in western Africa
Clements,Archie CA; Firth,Sonja; Dembelé,Robert; Garba,Amadou; Touré,Seydou; Sacko,Moussa; Landouré,Aly; Bosqué-Oliva,Elisa; Barnett,Adrian G; Brooker,Simon; Fenwick,Alan;
Bulletin of the World Health Organization , 2009, DOI: 10.1590/S0042-96862009001200012
Abstract: objective: to predict the subnational spatial variation in the number of people infected with schistosoma haematobium in burkina faso, mali and the niger prior to national control programmes. methods: we used field survey data sets covering a contiguous area 2750 × 850 km and including 26 790 school-age children (5-14 years old) in 418 schools. the prevalence of high- and low-intensity infection and associated 95% credible intervals (cris) were predicted using bayesian geostatistical models. the number infected was determined from the predicted prevalence and the number of school-age children in each km2. findings: the predicted number of school-age children with a low-intensity infection was 433 268 in burkina faso, 872 328 in mali and 580 286 in the niger. the number with a high-intensity infection was 416 009, 511 845 and 254 150 in each country, respectively. the 95% cris were wide: e.g. the mean number of boys aged 10-14 years infected in mali was 140 200 (95% cri: 6200-512 100). conclusion: national aggregate estimates of infection mask important local variations: e.g. most s. haematobium infections in the niger occur in the niger river valley. high-intensity infection was strongly clustered in western and central mali, north-eastern and north-western burkina faso and the niger river valley in the niger. populations in these foci will carry the bulk of the urinary schistosomiasis burden and should be prioritized for schistosomiasis control. uncertainties in the predicted prevalence and the numbers infected should be acknowledged by control programme planners.
Post-Infectious Acute Glomerulonephritis in Child: Epidemiological, Clinical and Evolutionary Aspects in Gabriel Touré Teaching Hospital in Mali  [PDF]
Mariam Sylla, Fatoumata Dicko-Traoré, Abdoul Karim Doumbia, Aminata Coulibaly, Abdoul Aziz Diakité, Modibo Sangaré, Pierre Togo, Fousseyni Traoré, Amadou Touré, Djènèba Konaté, Karamoko Sacko, Belco Maiga, Fatoumata Léonie Diakité, Lala N’Drainy Sidibé, Mohamed Elmouloud Cissé, Adama Dembélé, Hawa Diall, Oumar Coulibaly, Ibrahim Hamadou, Leyla Maiga, Issiaka Koné, Boubacar Togo, Toumani Sidibé
Open Journal of Pediatrics (OJPed) , 2018, DOI: 10.4236/ojped.2018.84036
Abstract: Introduction: Acute post-infectious glomerulonephritis (APIGN) can be serious due to its complications that still occur in our countries. In this work, we aimed to study the epidemiological, clinical, biological and evolutionary aspects of APIGN. Patients and methods: We conducted a retrospective, descriptive study from January 1st, 2015 to December 31st, 2017 in the pediatric ward of the Gabriel Touré Teaching Hospital in Bamako. All children hospitalized for APIGN were included. Results: In two years, we included 10 children aged 7 years old on average; all from low socioeconomic backgrounds. The sex ratio was 1.5. On average, the children spent 15.8 days before our consultation. Edema was the main reason for consultation. We found a history of infection and high blood pressure in 30% each, and renal failure in 10% of the children. Hematuria and proteinuria were detected in 100% and 90%, respectively. Hypocomplementemia was observed in 66.6%. One third of the children had a positive antistreptolysin O. The average duration of hospital stay was 11.2 days. The evolution was favorable in 90%. Kidney failure was the leading cause of death. Conclusion: Acute post-infectious glomerulonephritis is still a reality in our context. Emphasis should be put on its prevention by improving the hygienic conditions, detection and the management of
Surgical Management of Larges Goiters in the ENT Department of CHU Mother and Child “Luxembourg”  [PDF]
Youssouf ? Sidibé, Abdoul Wahab Haidara, Djibril Samaké, Abdoulaye Kanté, Siaka Soumaoro, Boubacary Guindo, Nagnouma Camara, Mamadou Karim Touré, Mahmoud Cissé, Amadou Djibo, Youssouf Djigui Diakité, Boubacar Sanogo, Mohamed Amadou Ké?ta
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2019, DOI: 10.4236/ijohns.2019.84016
Abstract: Objectives: To study the clinical and therapeutic profiles of voluminous goiter. Patients and Methods: We carried out a descriptive and prospective study, relating to a series of 30 cases of voluminous goitre, collected in the Department of Otorhinolaryngology and cervicofacial surgery (ENT and CCF) of the CHU Luxembourg Mother Child of Bamako. It has been spread over a period of 4 years from January 2015 to December 2018. Patients of all ages operated for large goitre at the ENT Department of CHU Luxembourg Mother Enfant were included. Results: In 4 years we collected 30 cases of voluminous goitre; during this period we realized 180 thyroidectomies, i.e. frequency of 16.67%. The average age was 51.37 years with an extreme ranging from 38 to 65 years. Females were common in 66.7% with a sex ratio of 0.50. The long duration of evolution has been 40 years. The sign of compression was found in 85.7%. The physical examination found a mobile swelling, hard and painless in all patients with normal endolaryngeal examination; there was no cervical lymphadenopathy. The lower dipping pole was found in 5 cases on CT. All our patients were euthyroid. The classification of TIRADS 2 was found in 80.0% of cases. Total thyroidectomy was frequent with 50.0% of cases. The average weight of the operative specimen was 586.67 g with extremes ranging from 500 g to 800 g. The size of the operative piece of 14 cm was the longest. Injury of internal jugular vein was found in 26.7% of cases. Colloid adenoma of the thyroid was found in 100% of cases, postoperative complications of the type of hematoma of the lodge in 3.3% of cases, the release of the operative wound in 10% of cases local superinfection in 7.1%. Signs of hypothyroidism were common with 50.0%. Postoperative nasofibroscopy found good vocal fold mobility in all patients. Conclusion: The large goiters have become rare because of the early management of thyroid nodule. Its management must allow the prevention of recurrent and parathyroid morbidity.
Comparative Study of the Parallelization of the Smith-Waterman Algorithm on OpenMP and Cuda C  [PDF]
Amadou Chaibou, Oumarou Sie
Journal of Computer and Communications (JCC) , 2015, DOI: 10.4236/jcc.2015.36011
Abstract: In this paper, we present parallel programming approaches to calculate the values of the cells in matrix’s scoring used in the Smith-Waterman’s algorithm for sequence alignment. This algorithm, well known in bioinformatics for its applications, is unfortunately time-consuming on a serial computer. We use formulation based on anti-diagonals structure of data. This representation focuses on parallelizable parts of the algorithm without changing the initial formulation of the algorithm. Approaching data in that way give us a formulation more flexible. To examine this approach, we encode it in OpenMP and Cuda C. The performance obtained shows the interest of our paper.
Improving Global Performance on GPU for Algorithms with Main Loop Containing a Reduction Operation: Case of Dijkstra’s Algorithm  [PDF]
Amadou Chaibou, Oumarou Sie
Journal of Computer and Communications (JCC) , 2015, DOI: 10.4236/jcc.2015.38005
Abstract: In this paper, we study the impact of copying data in GPU computing. GPU computing allows implementing parallel computations at low cost: a GPU can be purchased at under USD 500. Many studies have shown that GPU can be used to speed up the calculations. But for algorithms requiring doing a part of the calculations on GPU and another part on CPU, alternately, latency due to the copy of the data is a performance degradation factor. To illustrate this, we consider the Dijkstra’s algorithm on the shortest path used in solving optimization problems. This algorithm is very heavy to run on sequential machine. So, we are considering a parallel approach on GPU. Note that Dijkstra’s algorithm has been subject of many implementations on GPU. In the present work, we use two platforms with external GPU. Graphs are represented in adjacency matrix. During the computation of this algorithm, intermediates results are copied from GPU to CPU or from CPU to GPU. The purpose of this work is to measure the impact of these copies in the overall performance of the algorithm. For that we calculate time due to the copying data’s implementation; then we compare results with implementation computing only on CPU memory (zero-copy). The real impact shown by experiments demonstrates the interest of this study. GP-GPU programmers have to think that they will use either memory zero-copy or GPU memory. The challenge for GPU’s manufacturers is how to reduce this impact.
Investigations into Some Simple Expressions of the Gamma Function in Wind Power Theoretical Estimate by the Weibull Distribution  [PDF]
Siaka Touré
Journal of Applied Mathematics and Physics (JAMP) , 2019, DOI: 10.4236/jamp.2019.712209
Abstract: The Weibull distribution is a probability density function (PDF) which is widely used in the study of meteorological data. The statistical analysis of the wind speed v by using the Weibull distribution leads to the estimate of the mean wind speed < v >, the variance of v around < v > and the mean power density in the wind. The gamma function Γ is involved in those calculations, particularly Γ (1+1/k), Γ (1+2/k) and Γ (1+3/k). The paper reports the use of the Weibull PDF f(v) to estimate the gamma function. The study was performed by looking for the wind speeds related to the maximum values of f(v), v2 f(v) and v3 f(v). As a result, some approximate relationships were obtained for Γ (1+1/k), Γ (1+2/k) and Γ (1+3/k), that use some fitting polynomial functions. Very good agreements were found between the exact and the estimated values of Γ (1+n/k) that can be used for the estimation of the mean wind speed < v >, the variance σ2 of the wind speed v; around the mean speed and the average wind power density.
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