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Search Results: 1 - 10 of 751 matches for " Aluízio; "
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The role of the scientific research in the control of schistosomiasis in endemic areas
Prata, Aluízio;
Memórias do Instituto Oswaldo Cruz , 2004, DOI: 10.1590/S0074-02762004000900002
Abstract: the way the researches established the lines of direction for considering fight against schistosomiasis on the double aspect of transmission and morbidity control is outstanding. chemotherapy in the morbidity control is emphasized. the research priorities for schistosomiasis control are mentioned.
Evolution of the clinical and epidemiological knowledge about Chagas disease 90 years after its discovery
Prata, Aluízio;
Memórias do Instituto Oswaldo Cruz , 1999, DOI: 10.1590/S0074-02761999000700008
Abstract: three different periods may be considered in the evolution of knowledge about the clinical and epidemiological aspects of chagas disease since its discovery: (a) early period concerning the studies carried out by carlos chagas in lassance with the collaboration of other investigators of the manguinhos school. at that time the disease was described and the parasite, transmitters and reservoirs were studied. the coexistence of endemic goiter in the same region generated some confusion about the clinical forms of the disease; (b) second period involving uncertainty and the description of isolated cases, which lasted until the 1940 decade. many acute cases were described during this period and the disease was recognized in many latin american countries. particularly important were the studies of the argentine mission of regional pathology studies, which culminated with the description of the roma?a sign in the 1930 decade, facilitating the diagnosis of the early phase of the disease. however, the chronic phase, which was the most important, continued to be difficult to recognize; (c) period of consolidation of knowledge and recognition of the importance of chagas disease. studies conducted by laranja, dias and nóbrega in bambuí updated the description of chagas heart disease made by carlos chagas and eurico villela. from then on, the disease was more easily recognized, especially with the emphasis on the use of a serologic diagnosis; (d) period of enlargement of knowledges on the disease. the studies on denervation conducted in ribeir?o preto by fritz k?berle starting in the 1950 decade led to a better understanding of the relations between chagas disease and megaesophagus and other visceral megas detected in endemic areas.
Yellow fever
Prata, Aluízio;
Memórias do Instituto Oswaldo Cruz , 2000, DOI: 10.1590/S0074-02762000000700031
Abstract: with the infestation by aedes aegypti, urban yellow fever might already exist. this did not occur because of either the lacking of a sufficient contact between the diseased individual and the a. aegypti or perhaps because this, after sixty years without transmitting the virus, needs an adaptation phase to infecting again.
Influence of the host related factors in the development of the hepatosplenic form of schistosomiasis mansoni
Prata, Aluízio;
Memórias do Instituto Oswaldo Cruz , 1992, DOI: 10.1590/S0074-02761992000800005
Abstract: the frequency of hepatosplenomegaly in endemic areas is not proportional to the fecal ova count. this may be explained by epidemiological genetic. the occurrence of two or more cases of schistosomal hepatosplenomegaly in nuclear family is much higher than expected. the concentration is higher among siblings than it is among mothers and children of further and children. it is not significant between father and mother. if the mother, instead of the father has hepatosplenic schistosomiasis the relative risk for the child to acquire hepatosplenomegaly is at least five times (the maternal affect). the inbreeding is highler in the hepatosplenic than in the hepatointestinal patients. in some areas in brazil the hepatosplenic form of the schistosomiasis mansoni occurs with much higher frequency in whites than in blacks. after treatment, reversion of hepatosplenic schistosomiasis occurs more frequently in non-whithers. it seems that the resistance of blacks to the hepatosplenic form of schistosomiasis may be related to the glyoxalase system , perhaps associated to another genetic marker. the hepatosplenic schistosomiasis is less frequent in longilineal individuals. in some areas the hepatosplenic form of schistosomiasis is more frequent in a blood group of abo sistem. the family heredograms do not suggest a single mendelian inheritance, but probably a multifactorial and possibility poligenic one.
Perspectivas de novos tratamentos para o carcinoma tireoidiano avan?ado
Rodrigues, Aluízio;
Revista do Colégio Brasileiro de Cirurgi?es , 2006, DOI: 10.1590/S0100-69912006000300011
Abstract: in the treatment of thyroid cancer, the greatest problem existis in tumors that continue to grow or express recurrences, despite surgical, radioidine or t4 supressive therapies. improved knowledge of the molecular biology of tumors showed that elevated expression of oncogeneses, uncontrolled ativation of tyrosine cinase receptors and their signaling pathways, and inibition of programmed apoptosis are all important factors in the origin and evolution of tumors and their metastasis. the development of therapies targeted against especific molecular deregulation envolved in tumor progression is now been evaluated, with sucess, in various types of cancer. in thyroid cancer, target therapies using drugs, antibodies, genes, and small molecules are in development in preclinical studies and show a potential role in the managment of thyroid cancer, in the future. in this review, some of these studies are discussed.
In memoriam Philip Davis Marsden
Prata Aluízio
Revista da Sociedade Brasileira de Medicina Tropical , 1997,
Abstract:
Kenneth Eugene Mott
Prata Aluízio
Revista da Sociedade Brasileira de Medicina Tropical , 1997,
Abstract:
Evolution of the clinical and epidemiological knowledge about Chagas disease 90 years after its discovery
Prata Aluízio
Memórias do Instituto Oswaldo Cruz , 1999,
Abstract: Three different periods may be considered in the evolution of knowledge about the clinical and epidemiological aspects of Chagas disease since its discovery: (a) early period concerning the studies carried out by Carlos Chagas in Lassance with the collaboration of other investigators of the Manguinhos School. At that time the disease was described and the parasite, transmitters and reservoirs were studied. The coexistence of endemic goiter in the same region generated some confusion about the clinical forms of the disease; (b) second period involving uncertainty and the description of isolated cases, which lasted until the 1940 decade. Many acute cases were described during this period and the disease was recognized in many Latin American countries. Particularly important were the studies of the Argentine Mission of Regional Pathology Studies, which culminated with the description of the Roma a sign in the 1930 decade, facilitating the diagnosis of the early phase of the disease. However, the chronic phase, which was the most important, continued to be difficult to recognize; (c) period of consolidation of knowledge and recognition of the importance of Chagas disease. Studies conducted by Laranja, Dias and Nóbrega in Bambuí updated the description of Chagas heart disease made by Carlos Chagas and Eurico Villela. From then on, the disease was more easily recognized, especially with the emphasis on the use of a serologic diagnosis; (d) period of enlargement of knowledges on the disease. The studies on denervation conducted in Ribeir o Preto by Fritz K berle starting in the 1950 decade led to a better understanding of the relations between Chagas disease and megaesophagus and other visceral megas detected in endemic areas.
Yellow fever
Prata Aluízio
Memórias do Instituto Oswaldo Cruz , 2000,
Abstract: With the infestation by Aedes aegypti, urban yellow fever might already exist. This did not occur because of either the lacking of a sufficient contact between the diseased individual and the A. aegypti or perhaps because this, after sixty years without transmitting the virus, needs an adaptation phase to infecting again.
Ganhos em características morfológicas por sele??o em popula??es de trigo
Cavassim, José Elzevir;Borém, Aluízio;
Scientia Agricola , 1999, DOI: 10.1590/S0103-90161999000400015
Abstract: gain by selection was estimated for three traits, in six wheat populations (triticum aestivum l.) evaluating: plant height, number of grains per spike and spike length. the study was conducted in vi?osa, mg, brazil in crosses made between the varieties: bh 1146 and br 24, of high stature, br 12 and embrapa 22, of short stature, consisting of a balanced diallel, without self pollination. the evaluations were made in the generations f3 and f4. in generation f3, the selection of individual plants was accomplished based on plant height. the 20 tallest plants and the 20 shortest were harvested in each population, and submitted to a progeny test in generation f4. predictions of genetic gains, were obtained using three simulations: selection among families, selection within families and mass selection. the selection differential varied from 5 to 25%. the gains showed great variation among populations and procedures. the results suggested the possibility of gains in the selection of all characteristics. the procedure that showed the highest gain was the selection among families and mass selection.
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