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Search Results: 1 - 10 of 4305 matches for " Alma Rosales-Hernandez "
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Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states
Jose A Martinez, Manami Kasamatsu, Alma Rosales-Hernandez, Leah R Hanson, William H Frey, Cory C Toth
Molecular Pain , 2012, DOI: 10.1186/1744-8069-8-3
Abstract: We used intranasal, intrathecal, and near-nerve chamber forms of delivery of varying concentrations of pregabalin or saline delivered over 14 days in rat models of experimental diabetic peripheral neuropathy and spinal nerve ligation. As well, radiolabelled pregabalin was administered to determine localization with different deliveries. We evaluated tactile allodynia and thermal hyperalgesia at multiple time points, and then analyzed harvested nervous system tissues for molecular and immunohistochemical changes in CaVα2δ-1 protein expression. Both intrathecal and intranasal pregabalin administration at high concentrations relieved NeP behaviors, while near-nerve pregabalin delivery had no effect. NeP was associated with upregulation of CACNA2D1 mRNA and CaVα2δ-1 protein within peripheral nerve, dorsal root ganglia (DRG), and dorsal spinal cord, but not brain. Pregabalin's effect was limited to suppression of CaVα2δ-1 protein (but not CACNA2D1 mRNA) expression at the spinal dorsal horn in neuropathic pain states. Dorsal root ligation prevented CaVα2δ-1 protein trafficking anterograde from the dorsal root ganglia to the dorsal horn after neuropathic pain initiation.Either intranasal or intrathecal pregabalin relieves neuropathic pain behaviours, perhaps due to pregabalin's effect upon anterograde CaVα2δ-1 protein trafficking from the DRG to the dorsal horn. Intranasal delivery of agents such as pregabalin may be an attractive alternative to systemic therapy for management of neuropathic pain states.Neuropathic pain is a consequence of nerve damage or disease in the central and/or peripheral nervous system such as with diabetes and trauma. The clinical presentation of neuropathic pain includes hyperalgesia, allodynia, and spontaneous pain [1]. Its high prevalence in humans [2-4] has led to the development of a number of animal models of neuropathic pain, including diabetic peripheral neuropathy and spinal nerve ligation.Changes within the nervous system associated with
Distance Measure Based Rules for Voltage Regulation with Loss Reduction  [PDF]
Y. Rosales Hernandez, T Hiyama
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2009, DOI: 10.4236/jemaa.2009.12013
Abstract: This paper presents a rule-based technique to control the voltage in a power transmission network. Transformers with a tap changer installed in the system are selected by the proposed technique as control devices. For each bus under volt-age violation, the most effective control device is selected by using the minimum electric distance criteria. In order to demonstrate the efficiency of the method, several simulations were performed using an IEEE 30-bus network as a model system. The distance measure technique is compared with classic voltage regulation approach and a genetic algorithm based. The results obtained show the robustness of the proposed method.
Disrupted by violence: children's well-being and families' economic, social, and cultural capital in Ciudad Juarez, Mexico
Hernandez,Alma A.; Grineski,Sara E.;
Revista Panamericana de Salud Pública , 2012, DOI: 10.1590/S1020-49892012000500004
Abstract: since 2008, ciudad juarez (chihuahua, mexico) has been undergoing a wave of violence due to a drug war, making the city a difficult environment in which to raise a family. this study uses qualitative methodology that incorporates 16 in-depth interviews with parents of children ages 0-5 years and 9 sets of photos from a subset of interviewed parents. the study explores how families' economic, social, and cultural capital has been disrupted by the violence and how it affects children's well-being. social and economic capital declined significantly because of the violence as families experienced crime, had increased difficulty finding and maintaining employment, and decreased their interactions outside the home. interviews also suggested that opportunities to gain cultural capital decreased because of this isolation. understanding the detrimental effects of violence on families' capital can contribute to understanding children's well-being in violence-stricken communities.
N2O Formation in Selective Non-catalytic NOx Reduction Processes  [PDF]
Crisanto Mendoza-Covarrubias, Carlos E. Romero, Fernando Hernandez-Rosales, Hans Agarwal
Journal of Environmental Protection (JEP) , 2011, DOI: 10.4236/jep.2011.28126
Abstract: Nitrous oxide is not an environmentally regulated species in the U.S., but it does participate in the stratospheric ozone chemistry and contributes to the greenhouse effect. Nitrous oxide has been found to be a by-product of the selective non-catalytic reduction process. Chemical kinetic calculations demonstrated that the formation of nitrous oxide in the urea-based selective non-catalytic reduction process is linked to the conversion of NO by cyano species released from the process parent compounds. This conversion occurs within in temperature window between 850 and 1050℃. With urea injection, nitrous oxide emissions represent up to 20 percent conversion of the NOx reduced. The amount of nitrous oxide formed depends primarily on the process temperature, the amount of chemical injected, the initial NOx level, and the carbon monoxide level in the gas stream. These observations, which were based on the chemical kinetics of the process, should be considered in designing selective non-catalytic reduction systems to minimize nitrous oxide by- product formation.
Developing a Network of Community Health Workers: Improving the Lives of Migrant Farmworkers  [PDF]
María Isabel Ortega-Vélez, Cecilia Rosales, Patricia Aranda Gallegos, Alma Delia Contreras Paniagua, Luis Valdez, Jill De Zapien
Open Journal of Social Sciences (JSS) , 2016, DOI: 10.4236/jss.2016.410011
Abstract: One of the main strengths of today’s global food system is the labor force. Within emergent countries, farmworkers are an important element of competitiveness. However, food production that frequently stands in developed countries family tables rests upon the usually precarious living and health conditions of farmworkers, especially those that should migrate from regions that are far from the agribusiness where they work and live most of the year. Furthermore, healthcare becomes a challenging task because of cultural, socioeconomic and ethnic barriers. The aim of this study was to develop and evaluate a Community Health Worker (CHW) training model among agricultural Mexican migrant farmworkers, focusing on strengthening a health prevention environment conducive to improve health. This was a qualitative action-driven research carried out in southern Mexico communities as well as at northwest Mexico agribusiness. The project was implemented in four stages: needs assessment, curriculum design, training and implementation and process evaluation. The socioecological model guided our methodological and analytical process; we followed a Community Based Participatory Approach (CBPA) to interview and train a network of 40 CHW. Results showed that CHW’s main health priorities were dehydration and heat stroke, respiratory infections, gastrointestinal infections, work accidents, hygiene, nutrition, as well as mental health including substance abuse and depression. Training evaluation 1) improved communication between middle management and migrant farmworkers, as well as between middle management and farm administrators, 2) increased middle management consciousness about farmworkers health needs and responsibility, and 3) increased awareness about how improving the environment could help prevent diseases.
Unilateral Impact of Altered Loading by Changing Teeth Height on the TMJ Fibrocartilage: Disc and Condyle of Wistar Rats  [PDF]
Roxanne M. Olvera-Farias, Jose Raymundo Cruz-Perez, Rogelio Salinas-Gutierrez, Jose Antonio Guerrero-Diaz de Leon, Juan B. Kouri-Flores, Raul Rosales-Iba?ez, David Masuoka Ito, Alma Lilian Guerrero Barrera
Microscopy Research (MR) , 2016, DOI: 10.4236/mr.2016.42003
Abstract: Temporomandibular joint (TMJ) is sensitive to loading and mechanical stress that provokes morphological changes produced by the impact in the occlusal plane. Here, this impact is evaluated in TMJ articular disc and articular cartilage using an in vivo model of unilateral occlusal plane impact and by analysis of serial tissue sections stained with Hematoxylin-Eosin (H-E) or with Masson trichrome technique. Thus, six groups of 5 Wistar rats (200 - 250 g) are subjected to biomechanical dental stimulation by placing unilateral resin occlusal interference, or unilateral tooth wear made by upper left molars artificial mechanical devastation (1 control and 2 experimental groups for each treatment). Each treatment is evaluated two times at 1 and 15 days post-treatment. By H-E staining, control groups show chondrocytes arrangement as several cord cell groups in comparison with the experimental groups, which show an arrangement in one cord cell along of articular disc. However, this yields no significant difference (p < 0.05) in cell number between control and experimental groups. In contrast, in articular cartilage chondrocytes are random distributed along the superficial zone in control groups, while in experimental groups cell-free regions are observed in superficial zone. An image Blue hue analysis for trichrome stain is performed to quantify collagen; this shows a significant collagen decrease (p < 0.05) in almost all experimental groups compared with the controls. A degenerative process biomechanically induced by unilateral occlusal plane modification, causes cell and tissue changes on the TMJ structures that remain the degenerative changes observed in early osteoarthritis.
Hernandez-Jaramillo,Alma; Patricia Pinzón,Olga; Parrado-Rosselli,ángela;
Colombia Forestal , 2012,
Abstract: seed predation has been considered as a selective process that decreases reproductive fitness of plant species. fruits and seeds of sapindus saponaria collected in anolaima town, between 2009 and 2010 were used to characterize predation of leptostylus gibbulosus (cerambycidae) and its effects on germination based on the relation within incidence and severity attack and size of fruit and seeds. results show that l. gibbulosus affected 25 % of seed under study and considerably reduced germination and reproductive fitness of predated seeds, principally in large seeds. the association between l. gibbulosus and s. saponaria seeds is registered for the first time in colombia.
The US/Mexico Border: A Binational Approach to Framing Challenges and Constructing Solutions for Improving Farmworkers’ Lives
Cecilia Rosales,Maria Isabel Ortega,Jill Guernsey De Zapien,Alma Delia Contreras Paniagua,Antonio Zapien,Maia Ingram,Patricia Aranda
International Journal of Environmental Research and Public Health , 2012, DOI: 10.3390/ijerph9062159
Abstract: Mexican migrant and seasonal farmworkers in the US-Mexico border region face health hazards and occupational risks and are becoming commonly known in the public health literature. According to several studies, farmworkers have high levels of chronic diseases such as diabetes and respiratory problems, are at risk for infectious diseases, and experience among the highest incidences of work-related injuries of any profession. The findings from two studies are considered and presented with the objective of contributing to an overall understanding of migrant farmworkers as a workforce moving across national boundaries and affected by the work environments and health stressors both shared and unique to each context. We propose a binational approach to comprehensively address the health problems and socioeconomic challenges faced by migrant and seasonal farmworkers. In this paper we present the results of two distinct but complementary studies of farmworker health on the Arizona-Sonora border.
Fuzzy Causal Ordering of Events in Distributed Systems
Luis A. Morales Rosales,Saul E. Pomares Hernandez,Gustavo Rodriguez Gomez
Journal of Applied Sciences , 2009,
Abstract: Event ordering is an important research subject in Distributed Systems (DS). Event ordering addresses the problem of establishing a certain order among the events that occur in DS according to some particular criteria. The types of event orderings used for DS are no order, FIFO, causal, Δ-causal, total and causal-total. They mainly differ in the degree of asynchronous execution allowed. One of the most important orderings is the Causal Order (CO), which is based on Lamport’s happened-before relation. It establishes that the events must be seen in the cause-effect order as they occur in the system. However, for certain applications, for example multimedia synchronization, where some degradation of the system is allowed, ensuring the CO based on Lamport’s relation is rigid and negative affect the performance of the system. In this study, it is introduced a new ordering for DS in order to achieve a more asynchronous execution than the CO, this new ordering is called Fuzzy Causal Order (FCO). Besides, it is defined the Fuzzy Causal Relation (FCR) and Fuzzy Causal Consistency (FCC), the FCR establishes logical dependencies based on the precedence of events and by considering some kind of distance between their occurrences. With the notion of distance was possible to establish a cause-effect measure between two events a and b that indicates how long ago an event a happened before an event b. Through the FCC it was possible to determine how good the performance of the system is at a given moment. The usefulness of the FCO, FCR and FCC is showed by applying them to the concrete problem of intermedia synchronization in DS.
A Global Kinetic Mechanism for the Prediction of Hg Oxidation by a Chlorine Species
Hans Agarwal,Carlos E. Romero,Fernando Hernandez Rosales,Crisanto Mendoza-Covarrubias
Energy Science and Technology , 2012, DOI: 10.3968/j.est.1923847920120401.332
Abstract: This paper presents a global kinetic model developed from laboratory test results. The model consists of five global reactions - two reversible and three irreversible. The reaction constants for the Arrhenius expression formulation were determined from a set of 35 experiments involving a variety of flue gas compositions that include bulk gases (N2, CO2 and O2.) and trace gases (NO, SO2, Hg, Cl2); at a range of temperatures (from 540 °C to 166 °C) and a variety of residence times (between 2.7 and 3.3 seconds). The values obtained for the reaction constants were further used to predict experimental data from eleven published mercury data sources. The predicted values corresponded very well compared to the observed published data.Key words: Kinetics model; Mercury emission; Homogeneous mercury oxidation
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