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Search Results: 1 - 10 of 29845 matches for " Alfredo Dias;Barreto-Filho "
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Rela??o entre a Escala de Ades?o Terapêutica de oito itens de Morisky (MMAS-8) e o controle da press?o arterial
Oliveira-Filho, Alfredo Dias;Barreto-Filho, José Augusto;Neves, Sabrina Joany Felizardo;Lyra Junior, Divaldo Pereira de;
Arquivos Brasileiros de Cardiologia , 2012, DOI: 10.1590/S0066-782X2012005000053
Abstract: background: non-adherence to treatment is an important and often unrecognized risk factor that contributes to reduced control of blood pressure (bp). objective: to determine the association between treatment adherence measured by a validated version in portuguese of the 8-item morisky medication adherence scale (mmas-8) and bp control in hypertensive outpatients. methods: a cross-sectional study was carried out with hypertensive patients older than 18 years, treated at six of the family health strategy units in maceió (al), through interviews and home blood pressure measurements, between january and april 2011. adherence was determined by mmas-8 version translated for this study. the patients were considered adherent when they had a score equal to 8 at the mmas-8. results: the prevalence of adherence among the 223 patients studied was 19.7%, while 34% had controlled bp (> 140/90 mmhg). the average adherence value according to the mmas-8 was 5.8 (± 1.8). adherent patients showed to be more prone (or = 6.1, ci [95%] = 3.0 to 12.0) to have blood pressure control than those who reached mean (6 to <8) or low values (<6) at the adherence score. the portuguese version of mmas-8 was showed a significant association with bp control (p = 0.000). conclusion: the diagnosis of non-adherent behavior through the application of mmas-8 in patients using of antihypertensive medications was predictive of elevated systolic and diastolic bp.
Suspeita de Apneia Obstrutiva do Sono definida pelo Questionário de Berlim prediz eventos em pacientes com Síndrome Coronariana Aguda
Jesus, Eryca Vanessa S. de;Dias-Filho, Euvaldo B.;Mota, Bethania de M.;Souza, Luiz de;Marques-Santos, Celi;Rocha, Jo?o Bosco G.;Oliveira, Joselina L. M.;Sousa, Ant?nio C. S.;Barreto-Filho, José Augusto;
Arquivos Brasileiros de Cardiologia , 2010, DOI: 10.1590/S0066-782X2010005000103
Abstract: background: from a mechanistic standpoint, obstructive sleep apnea (osa) may further disturb cardiovascular homeostasis in the setting of acute coronary syndrome (acs). objective: we sought to investigate if a standardized clinical diagnosis of osa, in acute coronary syndrome patients, predicts the risk of cardiovascular events during hospitalization. methods: in a prospective cohort study, a group of 200 patients diagnosed with acs between september 2005 and november 2007 were stratified by the berlin questionnaire (bq) regarding the risk for osa (high or low risk). we tested if the subgroup of high risk for osa was prone to a higher frequency of cardiovascular events. the primary endpoint evaluated was a composite outcome of cardiovascular death, recurrent cardiac ischemic events, acute pulmonary edema and stroke during hospitalization. results: ninety four (47%) patients assessed by the bq were likely to have osa. high risk for osa was associated with a non-significant higher mortality (4.25% vs 0.94%; p=0.189), but a significant higher incidence of composite cardiovascular events (18.08% vs 6.6%; p=0.016). in the logistic regression model, multivariate predictors of composite cardiovascular events were age (or= 1.048; 95% ci 1.008 to 1.090; p=0.019), left ventricular ejection fraction (or= 0.954; 95% ci 0.920 to 0.989; p=0.010), and higher risk for osa (or= 3.657; 95% ci 1.216 to 10.996; p=0.021). conclusion: the use of a simple and validated questionnaire (bq) to identify patients with higher risk for osa may help in the prediction of cardiovascular outcome during hospitalization. moreover, our data suggests that osa is very common in patients with acs.
Síndrome ou pseudossíndrome metabólica?
Correia, Luis Cláudio Lemos;Latado, Adriana L.;Barreto-Filho, José Augusto;
Arquivos Brasileiros de Cardiologia , 2012, DOI: 10.1590/S0066-782X2012000400016
Abstract: metabolic syndrome has been proposed as a predictor of cardiovascular risk. however, such idea lacks strong scientific basis. this article reviews the evidence regarding that issue, challenging the existing paradigm of the prognostic value of metabolic syndrome.
Conseqüências em longo prazo da deficiência do horm?nio de crescimento
Oliveira, Carla R. P.;Pereira, Rossana M. C.;Barreto-Filho, José A. S.;Aguiar-Oliveira, Manuel H.;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2008, DOI: 10.1590/S0004-27302008000500005
Abstract: this article describes the long time consequences of the isolated and lifetime growth hormone (gh) deficiency using a single model of gh releasing hormone resistance (ghrh) due to a homozygous mutation in the ghrh receptor gene, in a hundred of subjects. these consequences include severe short stature with final height between -9.6 and -5.2 standard deviations below of the mean, with proportional reductions of the bone dimensions; reduction of the anterior pituitary corrected to cranial volume and the thyroid, the uterus, the spleen and left ventricular mass volume, all corrected to body surface, in contrast of pancreas and liver size, bigger than in controls, when equally corrected. body composition features included marked reduction in the amount of fat free mass (kg) and increase of fat mass percentage, with predominant abdominal deposit. in the metabolic aspects, we find increase in the total cholesterol and ldl cholesterol; reduction of the insulin and the insulin resistance assessed by homeostasis model assessment; increase of ultra sensitive c reactive protein and systolic body pressure in adults, although without evidences of premature atherosclerosis. other findings include smaller bone resistance, although above of the threshold of fractures, delayed puberty, normal fertility, small parity, anticipated climacteric and normal quality of life.
Transcranial doppler in sickle cell anaemia: evaluation of brain blood flow parameters in children of Aracaju, Northeast - Brazil
Melo, Hyder Arag?o de;Barreto-Filho, José Augusto S.;Prado, Roberto César P. do;Cipolotti, Rosana;
Arquivos de Neuro-Psiquiatria , 2008, DOI: 10.1590/S0004-282X2008000300015
Abstract: background: environmental factors interfere on sickle cell anaemia (sca). transcanial doppler (tcd) is important to evaluate cerebrovascular disease. objective: to evaluate brain haemodynamic profile of children with sca in sergipe. methods: cross sectional study (group1: sca patients aged 3-18; group2: age and sex matched healthy individuals). baseline brain flow was evaluated. results: group1=34 patients; group 2=81 controls. sca patients had mean velocity (mv)=125.69 cm/s±23.40; pulsatility index (pi)=0.66±0.10; middle cerebral artery ratio (mcar)=14.53±15.23; right anterior cerebral artery/right middle cerebral artery=0.77±0.20; left anterior cerebral artery/left middle cerebral artery=0.78±0.20. controls had mv=79.44±15.54; pi=0.82±0.11; mcar=13.19±13.77; right anterior cerebral artery/right middle cerebral artery=0.80±0.16; left anterior cerebral artery/left middle cerebral artery=0.84±0.18. mv and pi differences were statistically significant between groups. mv was related to age but not to gender. conclusion: mv evaluation using tcd was similar to international standards and possible to be used in our setting.
Estudo comparativo do perfil pró-aterosclerótico de estudantes de Medicina e de Educa??o Física
Resende, Marcelo de Aquino;Resende, Roberta Barreto Vasconcelos;Tavares, Rodrigo da Silveira;Santos, Carlos Roberto Rodrigues;Barreto-Filho, José Augusto Soares;
Arquivos Brasileiros de Cardiologia , 2010, DOI: 10.1590/S0066-782X2010005000061
Abstract: background: recent studies have demonstrated a strong association between physical activity, low level of cardiorespiratory fitness and the presence of cardiovascular risk factors. objective: compare the level of physical activity, level of cardiorespiratory fitness and cardiovascular risk in students of medicine and physical education. methods: at the first phase, the international physical activity questionnaire (ipaq) was used to quantify the physical activity level of 126 students from the 7th and 8th semesters of the physical education and medicine courses. at the second phase, 40 students were randomly selected (20 from each course) to undergo cardiovascular risk assessment and cardiorespiratory fitness. the following data were assessed 1) arterial pressure; 2) body mass index (bmi); 3) percentage of fat (electrical bioimpedance); 4) abdominal circumference (ac); 5) laboratory biochemical assessment; and 6) cardiorespiratory fitness (kline's test). results: the comparison of students of medicine and physical education, respectively, showed a higher frequency of individuals presenting: low level of physical activity (55% vs 15.0%; p = 0.008); pre-hypertension measured by sap (80% vs 25.0%; p = 0.000) and by dap (45% vs 5.0%; p = 0.003); overweight (50% vs 10.0%; p = 0.006); increased abdominal circumference (25% vs 0.0%; p = 0.017); increased total cholesterol (165 ± 28 vs 142 ± 28 mg/dl; p = 0.015); increased ldl-c (99 ± 27 vs 81 ± 23 mg/dl; p = 0.026); increased glycemia (81 ± 8.0 vs 75 ± 7.0 mg/dl; p = 0.013); lower cardiorespiratory fitness (48 ± 8.0 vs 56 ± 7.0 ml/kg/min; p = 0.001). conclusion: students of medicine presented lower levels of physical activity practice, lower level of cardiorespiratory fitness and higher frequency of cardiovascular risk factors, when compared to physical education students.
Papel emergente do eixo GH/IGF-I no controle cardiometabólico
Oliveira, Carla R.P;Meneguz-Moreno, Rafael A;Aguiar-Oliveira, Manuel H;Barreto-Filho, José A. S;
Arquivos Brasileiros de Cardiologia , 2011, DOI: 10.1590/S0066-782X2011001400012
Abstract: growth hormone (gh), the main regulator for post-natal growth, has important metabolic actions on different tissues, similar or opposite to insulin like growth factor i (igf-i), mainly produced by the liver after the binding of gh to its receptor. experiments with animal models indicate an important role of gh on insulin resistance although the igf-i role is not yet completely established. in humans, gh promotes an increase on lypolisis and lipid oxidation, while igf-i leads to an increase on lipid oxidation only in a chronic way. while growth actions are time-limited, metabolic and cardiovascular actions of the gh/igf-i axis are throughout life. gh anabolic effects have been used on chronic and hypercatabolic conditions, although investigations on the clinical outcomes are still scarce. in this paper, we intend to review gh metabolic actions experienced by animal models, studies with normal humans and gh deficient individuals, individuals with diabetes mellitus type 1 and metabolic syndrome individuals, hypercatabolic states and the relationship between gh and adipokines, endothelial disfunction and atherogenesis
índice de massa corporal apresenta boa correla??o com o perfil pró-aterosclerótico em crian?as e adolescentes
Costa, Geodete Batista;Horta, Naira;Resende, Zulmira Freire;Souza, Graziela;Barreto, Larissa Machado de Farias;Correia, Luis Henrique;Nascimento, Thiago Augusto;Rios, Clay Barreto;Barreto-Filho, José Augusto;Lopes, Heno Ferreira;
Arquivos Brasileiros de Cardiologia , 2009, DOI: 10.1590/S0066-782X2009000900010
Abstract: background: more recently, the association of different risk factors has been described as the metabolic syndrome. different definitions are being used for the same syndrome. regardless of the name or classification, it has been well established that a cardiovascular cluster including overweight/obesity, increased blood pressure, and lipid and glucose abnormalities are associated with an increased risk of atherosclerosis in adults. objective: the aim of this study was to correlate body mass index percentiles with blood pressure, insulin resistance index, and lipid profiles in children and adolescents, which characterize a proatherosclerotic profile. methods: cardiovascular risk factor clusters were evaluated in 118 children and adolescents divided according to body mass index percentile (bmip) quartiles: q1 (n=23) with bmip <50%, q2 (n=30) with bmip between 50 and 85%, q3 (n=31) with bmip between 85 and 93%, and q4 (n=34) with the bmip > 93%. statistically significant differences were not observed for age (f=2.1; p=0.10); sex (chi-square test=3.0; p=0.38), and ethnicity (chi-square test=4.7; p=0.20) between different quartiles. results: a statistically significant difference was observed for systolic bp (f=15.4; p<0.0001), diastolic bp (f=9.5; p<0.0001), glycemia (f=9.6; p<0.0001), insulin (f=12.9; p<0.0001), homair (f=30.8; p<0.0001), and triglyceride levels (f=2.7; p=0.05) between the different quartiles. conclusion: excess weight evaluated by bmip was associated with increased blood pressure, triglycerides, homair index, and low hdl-cholesterol, a proatherosclerotic profile in children and adolescents.
Ecocardiografia sob estresse físico na identifica??o de doen?a arterial coronariana em idosos com incompetência cronotrópica
Oliveira, Joselina Luzia Menezes;Góes, Thiago J?natas Santos;Santana, Thaiana Arag?o;Silva, Isabela Souza;Travassos, Thiago Figueiredo;Teles, Lívia Dantas;Barreto, Martha Azevedo;Barreto-Filho, José Augusto;D'Oliveira Junior, Argemiro;Sousa, Antonio Carlos Sobral;
Arquivos Brasileiros de Cardiologia , 2007, DOI: 10.1590/S0066-782X2007001400007
Abstract: background: chronotropic incompetence (cti) is frequent in elderly patients and may limit the role of the exercise test in the identification of coronary artery disease (cad) in this population. objective: to assess the value of cti in an elderly population in the diagnosis of cad. methods: a total of 3,308 patients were studied, 804 were elderly individuals (age > 65 years) who underwent exercise stress echocardiography (ese). based on the heart rate (hr) reached during the exercise test, were divided into two groups: g1 150 patients who did not reach 85% of the age-predicted hr, and g2 654 patients who did. the groups were compared to clinical characteristics, segmental left ventricular contractility rate (wmsi) and coronary angiography (cag). results: clinical characteristics were similar between the groups. wmsi was higher in g1 than in g2, both at rest (1.09 ± 0.21 versus 1.04 ± 0.15) and after exercise (1.15 ± 0.29 versus 1.08 ± 0.2) (p < 0.001). abnormalities in wall contractility were more frequent in g1 than in g2 (55% versus 37%; p < 0.05), thus suggesting that elderly with cti have a higher frequency of cad. cag was performed in 69% ese positive for myocardial ischemia. in the g1 group, 91% of the ese were true positive versus 84.5% in g2, that is, presence of obstructive coronary artery disease (> 50%). conclusion: cti is associated with a higher frequency of contractile alterations in the elderly population and adds a positive predictive value to ese in the identification of patients with obstructive cad.
Fun??o diastólica do ventrículo esquerdo em obesos graves em pré-operatório para cirurgia bariátrica
Tavares, Irlaneide da Silva;Sousa, Antonio Carlos Sobral;Menezes Filho, Raimundo Sotero;Aguiar-Oliveira, Manuel Hermínio de;Barreto-Filho, José Augusto;Brito, Amanda Ferreira de;Oliveira, Joselina Luzia Menezes;
Arquivos Brasileiros de Cardiologia , 2012, DOI: 10.1590/S0066-782X2012005000028
Abstract: background: obesity is a chronic and multifactorial disease, associated with increased cardiovascular risk, especially diastolic heart failure. objective: to evaluate left ventricular diastolic function in morbidly obese patients in the pre-operative for bariatric surgery, correlating it with cardiovascular risk factors and heart structure. methods: this is a cross-sectional study with 132 patients eligible for bariatric surgery submitted to transthoracic echocardiography assessment and of cardiovascular risk factors, as follows: 97 women (73.5%), mean age 38.5 ± 10.5 years and bmi of 43.7 ± 7.2 kg / m2. patients were divided into three groups: 61 with normal diastolic function, 24 with mild diastolic dysfunction and 47 with moderate/severe diastolic dysfunction, of which 41 with moderate diastolic dysfunction (pseudonormal pattern) and six with severe diastolic dysfunction (restrictive pattern). results: hypertension, age and gender were different in the groups with diastolic dysfunction. groups with dysfunction had higher left atrial diameter, left ventricular diameter, left atrial volume in four and two chambers, left atrial volume index and left ventricular mass index corrected for body surface area and height. conclusion: the high frequency of left ventricular diastolic dysfunction in the preclinical phase in morbidly obese patients justifies the need for careful echocardiographic assessment, aiming at identifying individuals at higher risk, so that early intervention measures can be carried out.
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