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Knowledge and Rates of Use of Preschool Consultation by the Mothers in the Area of Health Tshitenge/Democratic Republic of Congo  [PDF]
Jean Christophe Bukasa Tshilonda, Augustin Kadiata Bukasa, Zelda Nkongolo Kitenge, Isaac Kalenda Ilunga, Cedrick Ilunga Bimpa, Jean Pierre Kufua Katukumbanyi, Dominique Kapitena Mangola, Astrid Kabanga, Benedicte Bileo, Axel Ngoyi, Therese Kapenga Mitanta, Olivier Ejiba Nyongonyi, Paulin Kabamba Lupueka, Alain Ngoyi Kibambe, Jean Felix Kabangu, Geremie Kazadi, Alexis Ntambwe Mayombo, Andre Kazadi Mukendi
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105064
Abstract:
Introduction: The postponement of the preventive activities of the Provincial Division of Health of East Kasai 2016 revealed que le level of attendance of the preschool consultation is decreasing less and less in the Health Area Tshitenge. Thus, this study set the goal of determining the knowledge and use of maternal pre-school counseling in the Health Area Tshitenge. Methods: The survey method was used by means of a questionnary administered to mothers in this region, but more specifically, we collected data from 422 mothers responsible for randomly selected children aged 0 to 5 in the four health. Results: After analysis and analysis of the data with the computer tool, we obtained the following results: the rate of use of the preschool consultation service is 60.7%; the level of education, occupation and the number of children under 5 years of age have a strong influence on the use of preschool counseling; lack of knowledge about the most important activity of preschool counseling has a negative influence on its use. There is a link between the use of the preschool consultation and the most important activity of the preschool consultation for the respondent; there is also a link between this and an appointment on the map; and finally, the cost judgment of SPC strongly influences its use. Conclusion: In order to raise this activity, the revitalization of preschool consultation activities in the Tshitenge health area, the reinforcement of the parents’ awareness on the use of preschool counseling from 0 to 59 months, and the revival of visits to homes for children whose mothers drop out of preschool counseling sufficient are a basis.
Estimating the Number of Antiretroviral Treatment Facilities Based on the Wilson–Blower Method
Ntambwe Malangu
PLOS Medicine , 2005, DOI: 10.1371/journal.pmed.0020270
Abstract:
Estimating the number of antiretroviral treatment facilities based on the Wilson-Blower method.
Malangu Ntambwe
PLOS Medicine , 2005,
Abstract:
Influence of parents’ and caregivers’ characteristics on the outcomes of antiretroviral treatment in Ugandan children
Ntambwe Malangu
African Journal of Primary Health Care & Family Medicine , 2011, DOI: 10.4102/phcfm.v3i1.267
Abstract: Background: The purpose of this study was to investigate whether there was an association between characteristics of parents and caregivers, and the outcomes of antiretroviral treatment in children younger than 6 years treated at Mildmay Centre in Uganda. Methods: This study was a cross-sectional study based on the review of records. The records of children treated from January 2000 to July 2005 were included in the analysis as part of a larger study. Descriptive and inferential statistics were used in the analysis of data. Results: Of the 179 children, 57.3% were male, 53.4% were 4–5 years, and their median age was 4 years. The majority of children were cared for, in descending order, by their mothers, aunts, grandmothers, and fathers. Whilst 16.0% were orphans of both parents, 56.9% had one of their parents still alive. With regard to outcomes of antiretroviral treatment, it was found that a CD4 count of less than 15% was the most significant predictor of death, when treatment was initiated only at that late stage. When the influence of caregivers’ and parents’ characteristics on the outcomes of treatment were considered, the only factor that was associated significantly with clinical improvement was the ‘father’s unknown human immunodeficiency virus (HIV) status’. The data show that when the father was alive, as well as when both parents were alive, the children had a better chance of survival. Conclusion: The nature of the relationship between caregivers and children on antiretroviral treatment, as well as the HIV and living status of their parents seem to have little positive influence on the clinical, immunological, and survival outcomes of the children on treatment. More studies are needed to investigate other characteristics and relationships that may influence the outcomes of treatment. How to cite this article: Malangu N. Influence of parents’ and caregivers’ characteristics on the outcomes of antiretroviral treatment in Ugandan children. Afr J Prm Health Care Fam Med. 2011;3(1), Art. #267, 5 pages. http://dx.doi.org/10.4102/phcfm.v3i1.267
Analysis of Occupational Infections among Health Care Workers in Limpopo Province of South Africa
Ntambwe Malangu,Adelaide Legothoane
Global Journal of Health Science , 2012, DOI: 10.5539/gjhs.v5n1p44
Abstract: Objective: Occupational infections particularly hospital-acquired infections (HAIs) are a serious problem in the healthcare industry worldwide. This study purported to investigate their prevalence and risk factors among healthcare workers from Limpopo province of South Africa. Methods: Cases about occupational infectious diseases of healthcare workers from Limpopo province that were submitted to the Compensation Commissioner from January 2006 to December 2009 were reviewed. Results: The total number of cases of infectious diseases reported during the study period was 56; of these, 83.9% (47) of cases were for tuberculosis, 10.7% (6) for cholera, and 5.4% (3) for chickenpox. Nurses were the most affected. Risk factors associated with the acquisition of infection diseases were as follows. The majority of those infected were female (67.9%), aged over 40 years (57.1%), and who had worked for over 10 years (59.2%). With regard to length of time it took for one to be infected, overall it took 13.6±9.7 years from the year of employment to being infected. This duration was just 5.7±4.2 years in HCWs younger than 40 years versus 18.4±9.0 years in those 40 years and over (p=0.001); and 11.4±10.3 years in nurses versus 17.1±7.8 years in non-professional staff members (p=0.046). Mopani district, situated in a rural setting was the most affected as 24 of the 47 cases of tuberculosis occurred there. Conclusion: In conclusion, the most common occupational infection or hospital acquired infection among healthcare workers in Limpopo province of South Africa was tuberculosis. It infected mainly nurses from the rural health district of Mopani. Younger age and being a nurse were significant risk factors associated with being infected early.
Profile of acute poisoning in three health districts of Botswana
Mary Kasule,Ntambwe Malangu
African Journal of Primary Health Care & Family Medicine , 2009, DOI: 10.4102/phcfm.v1i1.10
Abstract: Background: This study sought to characterise acute poisoning cases seen in three health districts of Botswana. Method: A retrospective review of patients’ records was conducted and included patients treated from January 2004 to December 2005. Data on the demographic status of the patients, information about the poisonous agent(s) involved, and the circumstances and outcomes of the poisoning incidents were recorded on a pre-tested data collection form. Results: A total of 590 cases of acute poisoning were included in the analysis. The most affected age category was that of children aged less than six years, who constituted 33.4% of the cases. Most incidents were recorded in the urban district of Gaborone. Seventy-eight percent (78%) of the incidents were accidental, with the remainder being intentional. The poisonous agents involved were pharmaceuticals (26.6%), natural toxins (25.6%), household products (14.6%), foods (14.4%), alcohol (6.9%), traditional medicines (4.7%), unspecified agents (3.2%), and agrochemicals (2.7%). The most common route of poison exposure was by oral (82.2%), followed by dermal contact (16.5%), while the inhalation of gases occurred in 1.2% of cases. An incidence rate of 4.7/1000, a case fatality rate of 3.8/100, and 1.5% of deaths were recorded over the two-year period. Conclusion: In conclusion, it can be stated that acute poisoning involved mainly young children and resulted in an incidence rate of 4.7/1000, a case fatality rate of 3.8/100, and 1.5% of deaths over the two-year period. There were differences based on age category, gender and residence of the victims, the types of toxic agents involved, as well as the circumstances and the outcomes of the poisoning incidents. Given the fact that pharmaceuticals, natural toxins, household products and foods were the agents most commonly involved, targeted interventions should take these differences into account in addressing the problem of acute poisoning.How to cite this article: Kasule M, Malangu G. Profile of Acute Poisoning in Three Health Districts of Botswana. Afr J Prm Health Care Fam Med. 2009;1(1), Art. #10, 6 pages. DOI: 10.4102/phcfm.v1i1.10
Impact of adverse events of antiretroviral treatment on regimen change and mortality in Ugandan children
Ntambwe Malangu,Yvonne Karamagi
African Journal of Primary Health Care & Family Medicine , 2010, DOI: 10.4102/phcfm.v2i1.109
Abstract: Background: Outcomes of antiretroviral treatment have been documented in both developed and developing countries. It has been reported consistently that the treatment is associated with many adverse events. However, little is known about their impact on the quality of life, clinical management, and survival in children aged less than 6 years in Uganda. Objectives: The purpose of this study was to determine the prevalence of the adverse events of antiretroviral treatment, their impact on mortality and the change in regimens prescribed to children treated at Mildway Centre in Uganda. Method: A retrospective chart review was performed for children younger than 6 years, treated since the Mildway Centre was opened in 1999. In order to achieve a larger sample, the records of children treated from January 2000 to July 2005 were included in the study. A pre-tested data collection form was used to collate socio-demographic and clinical data of the patients. These included the documented adverse events, causes of death, stage of infection, duration of treatment, regimen prescribed, year of enrolment into the treatment program, as well as whether or not they were still alive. Descriptive statistics were used in the analysis of data. Results: Of the 179 children, the majority were males and had a median age of 4 years. The majority (58.8%) of children had suffered from severe immune depression since they met the WHO clinical stage III and IV, 73.8% had a baseline CD4T of less than 15%. Four regimens were prescribed to the children. The most common was a regimen containing zidovudine, lamivudine, and nevirapine (34.6%), followed by a regimen containing stavudine, lamivudine, and nevirapine (27.9%). Eleven children (6.1%) had their regimen changed, of which six (54.5%) were due to adverse events. The prevalence of adverse events was 8%; of the 14 documented adverse events, the most common were severe anaemia (3), vomiting (3), and skin rashes (3). After 12 months on treatment, 8% of the patients had died. The most common causes of death were infectious diseases (28.6%), severe anaemia (21.4%), and severe dehydration (21.4%). Conclusion: The prevalence of adverse events was 8%; they were responsible for 54.5% of regimen changes and 21.4% of deaths in children treated at the study site. These findings suggest the need for incorporating pharmacovigilance practices into the provision of antiretroviral treatment. How to cite this article: Malangu N, Karamagi Y. Impact of adverse events of antiretroviral treatment on regimen change and mortality in Ugandan children. Afr J
Tuberculosis and lactic acidosis as causes of death in adult patients from a regional hospital in Johannesburg
Ntambwe Malangu,Maryet Mogashoa
African Journal of Primary Health Care & Family Medicine , 2012, DOI: 10.4102/phcfm.v4i1.266
Abstract: Background: Tuberculosis and adverse effects have been shown to affect both the quality of life and the survival of patients on antiretroviral treatment. This study sought to investigate the causes of death in a sample of adult HIV-infected patients on antiretroviral treatment at Thembisa Hospital, Johannesburg, South Africa. Methods: A retrospective study was conducted by examining the charts of 498 adult patients treated from January 2004 to December 2006 at the antiretroviral clinic of a regional hospital in Johannesburg. A data collection form was used to collate both sociodemographic and clinical data. Results: The majority of the patients were female (71.7%) with a mean age of 37.7 ± 11.6 years, and in the age group of 18–77 years. The greater number of the patients was South African citizens, with only 2.2% citizens of other Southern African countries. At baseline, 29.9% had been on anti-tuberculosis treatment. Most of the patients had been prescribed the regimen comprising stavudine, lamivudine, and nevirapine or efavirenz; two of them (0.4%) were on the second line regimen made of zidovudine, didanosine, and lopinavir–ritonavir. At least one side effect was documented in 82.1% of patients; the ten most documented side effects were skin rashes (62.9%), peripheral neuropathy (48.4%), headaches (38.2%), chest pain (21.9%), coughing (21.7%), anaemia (21.5%), diarrhoea (19.3%), vomiting (16.7%), dizziness (15.3%), and lactic acidosis (11.2%). A mortality rate of 3.6% was recorded during the 2-year study period. Although the cause of death was undetermined in 11.1% of patients, 50.0% and 38.9% of deaths respectively were a consequence of tuberculosis and lactic acidosis. Conclusions: In addition to tuberculosis, side effects in particular, lactic acidosis was the other main cause of death in patients treated at the study site. These findings suggest that patients on regimens containing drugs that cause lactic acidosis should be closely monitored when the first complaints suggesting lactic acidosis are reported or noticed. La tuberculose et l’acidose lactique comme causes de décès de patients adultes d’un h pital régional à Johannesburg Contexte: Il a été prouvé que la tuberculose et ses effets négatifs affectaient à la fois la qualité de vie et la survie des patients sous traitement antirétroviral. Cette étude a cherché à enquêter sur les causes de décès d’un échantillon de patients adultes séropositifs sous traitement antirétroviral à l’h pital de Thembisa, à Johannesburg, en Afrique du Sud. Méthodes: Une étude rétrospective a été réalisée en examina
Estimation of Clinical, Immunological and Virological Failure of First Line Antiretroviral Treatment in Kinshasa, Democratic Republic of Congo  [PDF]
Erick Ntambwe Kamangu
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104560
Abstract:
Background: The prevalence of Human Immunodeficiency Virus (HIV) infection was 1.2% in the Democratic Republic of Congo, according to the Demographic Health Study report in 2014. In 2012, the severe failure rate to first-line ART in Kinshasa was estimated at more than 16%. Objective: The objective of this study is to determine the rate of clinical, immunological and virological failure in first-line treatment in Kinshasa. Methodology: At the 6th month of Antiretroviral Treatment (ART), 138 patients from a follow-up cohort of 8 centers in Kinshasa were received for paraclinical evaluations and analyses. The clinical and paraclinical parameters were recorded on the individual patient sheets as well as the survey forms. Clinical parameters, viral load and CD4 were evaluated at the 6th month of ART. Results: One hundred and thirty-eight (138) patients had returned for follow-up treatment, 81 women and 57 men. The average age of patients is 37 ± 12 years. The dominant age groups are those of 26 to 35 years and 36 to 45 years with 39 patients (28.3%) each, followed by those of 18 to 25 years (21.7%). One hundred and twenty-five (125) patients (90.5%) were in clinical stage 3 and 13 (9.5%) in clinical stage 4 according to the WHO classification. CD4 levels ranged from 98 to 1050 cells/mm3 and a median value of 560 cells/mm3. The median value of the patients’ VLs was 0.90 log10 copies of RNA/ml with respective minimum and maximum values of 0 and 4.82 log10 copies of RNA/ml. The virological failure rate was 24.6%. Conclusions: The rate of virological failure of first-line antiretroviral treatment of patients under treatment in Kinshasa is 24.6% for the year 2015.
Factors Associated with Acquired Infections Caesarian Wounds in Maternity Mbuji-Mayi/DR Congo  [PDF]
Jean Christophe Bukasa, Augustin Kadiata, Andre Guillaume Kabongo, Didier Lepelletier, Decas Blood Banza, Jean Jacques Bukasa, Félicien Ilunga, Andre Mutombo, Senghor Ngoyi Mbo, Angelique Bandimuna, Sébatien Kashimpo, Alexis Ntambwe, Stany Wembonyama
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104437
Abstract:
Introduction: The purpose of this study is to analyze the factors associated with nosocomial infections of caesarean section wounds in the maternity hospitals of the city of Mbuji-Mayi. Methods: This study was conducted in 25 maternities of general referral hospitals, clinics and hospitals in the city of Mbuji-Mayi during the period from 1 February to 1 June 2017, out of 171 parturients cesarized that were followed during a period of 4 months. A survey questionnaire was used to collect the data. Results: Out of 171 parturients monitored, surgical site infection developed 52 (SSI), an incidence of 30.4%. After analysis, nine factors were identified as associated post-caesarean SSI in Mbuji-Mayi city (p ≤ 0.05): age (p = 0.000), anemia (p = 0.000), prolonged duration of labor delivery (p = 0.001), premature rupture of the membranes before caesarean section (p = 0.044), prolonged duration after-rupture of the membranes (p = 0.000), preparation of the operative site by shaving (p = 0.029), surgery by general practitioner (p = 0.023), duration of operation greater than 60 minutes (p = 0.040), non-compliance with asepsis during dressing (p = 0.000). Conclusion: The fight against nosocomial infections must be a permanent concern: the prevention and regular monitoring of these infections must be the control strategies of each hospital structure, under the watchful eye of a coordination center for the fight nosocomial infections.
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