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Search Results: 1 - 10 of 3888 matches for " Alessandra Pratesi "
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Rietveld refinement of a natural cobaltian mansfieldite from synchrotron data
Matteo Zoppi,Giovanni Pratesi
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536808044127
Abstract: A structural refinement of a natural sample of a Co-bearing mansfieldite, AlAsO4·2H2O [aluminium orthoarsenate(V) dihydrate], has been performed based on synchrotron powder diffraction data, with 5% of the octahedral Al sites replaced by Co. Mansfieldite is the aluminium analogue and an isotype of the mineral scorodite (FeAsO4·2H2O), with which it forms a solid solution. The framework structure is based on AsO4 tetrahedra sharing their vertices with AlO4(H2O)2 octahedra. Three of the four H atoms belonging to the two water molecules in cis positions take part in O—H...O hydrogen bonding.
Realineamientos en torno a la guerra de Malvinas en la provincia del Chaco. Memoria y construcción de "heroísmos"
Ana Rosa Pratesi
Revista Theomai , 2007,
Abstract:
Adiponectin, diabetes and ischemic heart failure: a challenging relationship
Samuele Baldasseroni, Alessandro Antenore, Claudia Di Serio, Francesco Orso, Giuseppe Lonetto, Nadia Bartoli, Alice Foschini, Andrea Marella, Alessandra Pratesi, Salvatore Scarantino, Stefano Fumagalli, Matteo Monami, Edoardo Mannucci, Niccolò Marchionni, Francesca Tarantini
Cardiovascular Diabetology , 2012, DOI: 10.1186/1475-2840-11-151
Abstract: We evaluated the level of adiponectin in patients with ischemic HF, with and without type 2 diabetes, to elucidate whether the metabolic syndrome was able to influence the relationship between AD and HF.We demonstrated that AD rises in patients with advanced HF, but to a lesser extent in diabetics than in non-diabetics. Diabetic patients with reduced systolic performance orchestrated a slower rise of AD which began only in face of overt HF. The different behavior of AD in the presence of diabetes was not entirely explained by differences in body mass index. In addition, NT-proBNP, the second strongest predictor of AD, did not differ significantly between diabetic and non-diabetic patients. These data indicate that some other mechanisms are involved in the regulation of AD in patients with type 2 diabetes and coronary artery disease.AD rises across chronic heart failure stages but this phenomenon is less evident in type 2 diabetic patients. In the presence of diabetes, the progressive increase of AD in relation to the severity of LV dysfunction is hampered and becomes evident only in overt HF.The adipose tissue should not be regarded as a simple site of lipid storage [1]; indeed it is able to secrete several peptides with hormonal properties that are involved in energy homeostasis as well as modulation of inflammation and regulation of many immunological mechanisms [2]. This heterogeneous group of hormones is named adipokines. Among these, adiponectin (AD) is by far the most abundant protein secreted by the adipose tissue [3]. Although it is produced almost exclusively by adipocytes, plasma levels of AD are found to be inversely correlated to visceral adiposity and body mass index (BMI) [3]. AD promotes peripheral insulin sensitivity [4] and inhibition of liver gluconeogenesis [5]. As a matter of fact, hypoadiponectinemia is known to be the molecular link between obesity and insulin-resistance, at the base of metabolic syndrome [2]. AD is able to predict diabetes ons
O es?fago curto e o refluxo distal s?o fatores de risco para o refluxo proximal?
Serra, Humberto Oliveira;Gandolfi, Lenora;Pratesi, Riccardo;
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S?o Paulo) , 2010, DOI: 10.1590/S0102-67202010000400007
Abstract: background: it is not clear whether patients suffering from distal esophageal reflux also present high risk to proximal esophageal reflux. common sense suggests that reflux would more easily reach the pharynx in patients who have a smaller distance between the lower esophageal sphincter and the upper one and, thus, short esophagus. aim: to investigate if short esophageal length and presence of esophageal distal reflux are risk factors for proximal reflux among patients presenting respiratory symptoms. methods: a hundred and seven patients were evaluated prospectively by interview, esophagoscopy, manometry and 24-hour esophageal ph monitoring. student's t test (two-sided), spearman's rank correlation, chi-square and odds ratio were used in the statistical analysis. significance level was set at 0.05. results: respiratory symptoms that motivated the search for gastroesophageal reflux disease were cough 43 (40.2%); throat irritation 25 (23.4%), pharyngeal globe 23 (21.5%) and hoarseness 16 (14.9 %). by esophagoscopy, 22 (27.2%) presented some degree of esophagitis. a hiatal hernia was observed in 14 (17.5%) patients. according to manometry, 11 (10.8%) had lower esophageal sphincter hypotonia. the average esophageal body length was 24.3 (± 1.9) cm, ranging from 20 to 30 cm. the esophageal length was not associated with the presence of proximal esophageal reflux. as indicated by ph monitoring, 23 (21.5%) presented pathologic distal reflux and 12 (11.2%) had proximal reflux. conclusion: the esophageal length was not associated with the presence of proximal esophageal reflux. patients who had pathological distal esophageal reflux, independent of the esophageal length, were 4.6 times more likely to have proximal esophageal reflux.
Abnormalities in auditory evoked potentials of 75 patients with Arnold-Chiari malformations types I and II
Henriques Filho, Paulo Sergio A.;Pratesi, Riccardo;
Arquivos de Neuro-Psiquiatria , 2006, DOI: 10.1590/S0004-282X2006000400019
Abstract: objective: to evaluate the frequency and degree of severity of abnormalities in the auditory pathways in patients with chiari malformations type i and ii. method: this is a series-of-case descriptive study in which the possible presence of auditory pathways abnormalities in 75 patients (48 children and 27 adults) with chiari malformation types i and ii were analyzed by means of auditory evoked potentials evaluation. the analysis was based on the determination of intervals among potentials peak values, absolute latency and amplitude ratio among potentials v and i. results: among the 75 patients studied, 27 (36%) disclosed arnold-chiari malformations type i and 48 (64%) showed arnold-chiari malformations type ii. fifty-three (71%) of these patients showed some degree of auditory evoked potential abnormalities. tests were normal in the remaining 22 (29%) patients. conclusion: auditory evoked potentials testing can be considered a valuable instrument for diagnosis and evaluation of brain stem functional abnormalities in patients with arnold-chiari malformations type i and ii. the determination of the presence and degree of severity of these abnormalities can be contributory to the prevention of further handicaps in these patients either through physical therapy or by means of precocious corrective surgical intervention.
Abnormalities in auditory evoked potentials of 75 patients with Arnold-Chiari malformations types I and II
Henriques Filho Paulo Sergio A.,Pratesi Riccardo
Arquivos de Neuro-Psiquiatria , 2006,
Abstract: OBJECTIVE: To evaluate the frequency and degree of severity of abnormalities in the auditory pathways in patients with Chiari malformations type I and II. METHOD: This is a series-of-case descriptive study in which the possible presence of auditory pathways abnormalities in 75 patients (48 children and 27 adults) with Chiari malformation types I and II were analyzed by means of auditory evoked potentials evaluation. The analysis was based on the determination of intervals among potentials peak values, absolute latency and amplitude ratio among potentials V and I. RESULTS: Among the 75 patients studied, 27 (36%) disclosed Arnold-Chiari malformations type I and 48 (64%) showed Arnold-Chiari malformations type II. Fifty-three (71%) of these patients showed some degree of auditory evoked potential abnormalities. Tests were normal in the remaining 22 (29%) patients. CONCLUSION: Auditory evoked potentials testing can be considered a valuable instrument for diagnosis and evaluation of brain stem functional abnormalities in patients with Arnold-Chiari malformations type I and II. The determination of the presence and degree of severity of these abnormalities can be contributory to the prevention of further handicaps in these patients either through physical therapy or by means of precocious corrective surgical intervention.
Medicolegal autopsies in children: Experience of a department of Legal Medicine in Brazil  [PDF]
Manoel Eugenio dos Santos Modelli, Marco Agassiz de Almeida Vasques, Riccardo Pratesi
Forensic Medicine and Anatomy Research (FMAR) , 2013, DOI: 10.4236/fmar.2013.13008
Abstract: Purposes: The purpose of this study was to determine the pattern of mortality in children’s Federal District. Knowledge of the epidemiology of injuries is essential for planning, implementation and evaluation of preventive measures. Methods: We analyzed the forensic examination documents of all children under 12 years sent to the IML-DF, during 2010. The data analyzed included age, gender, cause of death (i.e.natural or external), mechanism of death (traffic accident, asphyxia, firearm injuries, poisoning, heat injuries) and the medical cause of death. Results: A large number of children (n = 123 total; n = 71 males, n = 52 females) were examined in the IML-DF, Brasília, Brazil. Mean age was 37.96 months, with a median of 12 months, and 21% of children were younger than 1 month. There were 62 cases (33 males and 29 female) classified as natural deaths. The average age for natural deaths was 18.72 months. Most cases of natural death occurred in the first year of life (n = 50), being prevalent in the first month of life (n = 24). Among the 62 cases analyzed, six were stillborns, 13 suffered intrauterine fetal distress (e.g. placental insufficiency, prematurity and meconium aspiration), 36 had lung problems (e.g. Acute respiratory distress syndrome (ARDS), bronchopneumonia, pulmonary hemorrhage, interstitial pneumonitis and infant respiratory distress syndrome (IRDS)), five had neurologicalproblems (e.g. hydrocephalus, hydranencephaly,convulsive seizures and meningitis) and two had undetermined cause of death. There were also isolated cases of heart disease, leukemia, diabetic ketoacidosis, peritonitis causedby acute appendicitisand amniotic bandsyndrome. There were 61 cases of deaths from external causes, as a consequence of the following: blunt instrument, firearm, physical agent (i.e.heat), physicochemical agent (i.e.asphyxia) and chemical agent (i.e.poisoning). Conclusions: The profile of deaths from external causesin this developing country follows a trend similar to trends reported in the literature for other developing countries. The majority of deaths are accidental, with traffic accidents being the most frequent cause, followed by asphyxia (i.e.aspiration of gastric contents and drownings). Sporadic cases of poisoning, injuries from firearms, accidents and fires also occur.
FMRI Reveals a Dissociation between Grasping and Perceiving the Size of Real 3D Objects
Cristiana Cavina-Pratesi, Melvyn A. Goodale, Jody C. Culham
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000424
Abstract: Background Almost 15 years after its formulation, evidence for the neuro-functional dissociation between a dorsal action stream and a ventral perception stream in the human cerebral cortex is still based largely on neuropsychological case studies. To date, there is no unequivocal evidence for separate visual computations of object features for performance of goal-directed actions versus perceptual tasks in the neurologically intact human brain. We used functional magnetic resonance imaging to test explicitly whether or not brain areas mediating size computation for grasping are distinct from those mediating size computation for perception. Methodology/Principal Findings Subjects were presented with the same real graspable 3D objects and were required to perform a number of different tasks: grasping, reaching, size discrimination, pattern discrimination or passive viewing. As in prior studies, the anterior intraparietal area (AIP) in the dorsal stream was more active during grasping, when object size was relevant for planning the grasp, than during reaching, when object properties were irrelevant for movement planning (grasping>reaching). Activity in AIP showed no modulation, however, when size was computed in the context of a purely perceptual task (size = pattern discrimination). Conversely, the lateral occipital (LO) cortex in the ventral stream was modulated when size was computed for perception (size>pattern discrimination) but not for action (grasping = reaching). Conclusions/Significance While areas in both the dorsal and ventral streams responded to the simple presentation of 3D objects (passive viewing), these areas were differentially activated depending on whether the task was grasping or perceptual discrimination, respectively. The demonstration of dual coding of an object for the purposes of action on the one hand and perception on the other in the same healthy brains offers a substantial contribution to the current debate about the nature of the neural coding that takes place in the dorsal and ventral streams.
Atherosclerosis in young Brazilians suffering violent deaths: a pathological study
Manoel ES Modelli, áurea S Cherulli, Lenora Gandolfi, Riccardo Pratesi
BMC Research Notes , 2011, DOI: 10.1186/1756-0500-4-531
Abstract: To evaluate the extent of atherosclerotic disease in young Brazilians, we conducted a study of the pathological alterations in the major arteries of victims of violent death. Samples of the right carotid artery, left coronary artery, and thoracic aorta of young victims of violent death were analyzed and graded in accordance with the histological atherosclerotic lesion types proposed by the American Heart Association. Samples were collected from 100 individuals who had died from external causes, aged from 12 to 33 years.The majority of cases (83%) were male, and 66% of deaths were homicides caused by firearms. The median age was 20.0 years and mean body mass index was 20.9 kg/m2. Of the right carotid artery specimens, 3% were normal, 55% had type I, 40% had type II, 1% had type III, and 1% had type IV atherosclerotic lesions. Of the left coronary artery specimens, 5% were normal, 48% had type I, 41% had type II, 3% had type III, and 3% had type IV lesions. Of the thoracic aorta specimens, none were normal, 13% had type I, 64% had type II, 22% had type III, and 1% had type IV lesions. Overall, 97.34% of arteries examined had some degree of atherosclerosis. The most common histological type was type II (foam cells). No thoracic aorta specimens were normal, and the coronary artery specimens had the most atherosclerosis.Our results show a high prevalence of atherosclerotic lesions among young people in Brazil. Intervention should be undertaken to decrease the rate of sudden cardiac death in the adult population.Cardiovascular diseases are a major cause of death in developed and developing countries, with a significant medical, social, and economic impact [1]. In general, the clinical manifestations of cardiovascular diseases, such as myocardial infarction, stroke, and peripheral vascular disease, are caused by an atherosclerotic process that is initiated during middle age. Sudden death of cardiac origin, defined as death which occurs within 6 hours of onset of symptoms o
Sleep disorder: a possible cause of attention deficit in children and adolescents with Chiari malformation type II
Henriques Filho, Paulo Sérgio Azeredo;Pratesi, Riccardo;
Arquivos de Neuro-Psiquiatria , 2009, DOI: 10.1590/S0004-282X2009000100008
Abstract: background: attention deficit may be related to sleep disorders in chiari malformation type ii (cmii). our aim is identify sleep disorders and their specific contribution in attention deficit. method: we selected 24 patients with cm ii and 24 without cm ii. dsm-iv criteria and a neuropsychological analysis were applied in all. all patients underwent full night polysomnography. results: 14 cm ii patients presented sleep apnea syndrome, rem sleep behavior disorder and periodic limb movement in sleep; six patients without cm ii presented sleep apnea syndrome. among these patients, 12 (six with cm ii and six without cm ii) presented attention deficit related to the sleep disorders. conclusion: sleep disorders may impair cognitive functions, as attention, and contribute to poor quality of learning also in patients with cm ii.
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