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Obituary: Yukio Mano (1943–2004)
Katsunori Ikoma
Journal of NeuroEngineering and Rehabilitation , 2005, DOI: 10.1186/1743-0003-2-1
Abstract: Associate Editor, Journal of NeuroEngineering and RehabilitationI was terribly shocked to hear of the tragic and sudden passing of Yukio Mano on November 7, 2004, at the age of 61. He had not been well this past year but had been working continuously until just ten days before his death.Yukio Mano (Figure 1) was born on August 26, 1943 in Aichi Prefecture, Japan. He studied medicine at Nagoya University School of Medicine, and graduated in 1968. After he completed his basic medical training in Japan, he began his medical career in the USA in 1972. He first worked as a resident at the Institute of Rehabilitation Medicine at New York University for two years, then in 1974 he moved to the Department of Neurology at Baylor College of Medicine working as an assistant instructor and resident for one year. In 1975, he became a research fellow at the University of Maryland School of Medicine, in the Neuromuscular Research Unit. Yukio Mano studied the most advanced techniques in the fields of rehabilitation medicine and neurology during his four-year stay in the USA. Upon returning to Japan in 1976, he resumed his research in rehabilitation medicine at Nagoya University and the National Center of Neurology and Psychiatry, Japan. In 1981, he became an associate professor in the Department of Neurology at Nara Medical University. He was responsible for running the rehabilitation department there as a specialist in rehabilitation medicine. Finally, he was granted a full professorship in Rehabilitation and Physical Medicine at Hokkaido University (Graduate) School of Medicine in 1995. Yukio Mano was committed to helping researchers studying rehabilitation medicine, as well as young medical doctors and therapists in the rehabilitation field. He extensively expanded the Rehabilitation Department of Hokkaido University, and my colleagues and I had expected his leadership to continue into the future.His research interest was rehabilitation medicine, especially brain plasticity. He w
A Bertini typr theorem for free arithmetic linear series
Hideaki Ikoma
Mathematics , 2013, DOI: 10.1215/21562261-3089037
Abstract: In this paper, we prove a version of arithmetic Bertini theorem asserting that there exists a strictly small and generically smooth section of a given arithmetically free graded arithmetic linear series.
Remarks on the arithmetic restricted volumes and the arithmetic base loci
Hideaki Ikoma
Mathematics , 2014,
Abstract: In this paper, we collect some fundamental properties of arithmetic restricted volumes (or arithmetic multiplicities) of the adelically metrized line bundles. The arithmetic restricted volume has the concavity property and characterizes the arithmetic augmented base locus as the null locus. We also show a generalized Fujita approximation for the arithmetic restricted volume.
On the concavity of the arithmetic volumes
Hideaki Ikoma
Mathematics , 2013,
Abstract: In this note, we study the differentiability of the arithmetic volumes along arithmetic R-divisors, and give some equality conditions for the Brunn-Minkowski inequality for arithmetic volumes over the cone of nef and big arithmetic R-divisors.
A numerical characterization of nef adelic divisors
Hideaki Ikoma
Mathematics , 2014,
Abstract: To a generically big adelic divisor, we can associate an arithmetic Okounkov body, which is a pair of the geometric Okounkov body and the concave transform of the Green functions. In this paper, we show that the infimum of the concave transform is given by the absolute minimum provided that the divisor is vertically nef. This is a partial generalization of results of Moriwaki (in the curve case) and of Burgos Gil-Moriwaki-Philippon-Sombra (in the toric case).
Association of serum osteoprotegerin with vascular calcification in patients with type 2 diabetes
Atsushi Aoki, Miho Murata, Tomoko Asano, Aki Ikoma, Masami Sasaki, Tomoyuki Saito, Taeko Otani, Sachimi Jinbo, Nahoko Ikeda, Masanobu Kawakami, San-e Ishikawa
Cardiovascular Diabetology , 2013, DOI: 10.1186/1475-2840-12-11
Abstract: The subjects were 124 patients with type 2 diabetes mellitus, including 88 males and 36 females with a mean (± SD) age of 65.6 ± 8.2 years old. Serum levels of osteoprotegerin, osteocalcin, fibroblast growth factor 23 (FGF23), 25-hydroxyvitamin D3 and adiponectin were measured by ELISA. Vascular calcification in the cervical artery was examined by ultrasound sonography. The subjects were divided into 4 quartiles depending on serum osteoprotegerin levels.Vascular calcification was significantly higher in the 4th quartile and significantly lower in the 1st quartile of serum osteoprotegerin levels, compared to other quartiles. There were no differences in serum osteoprotegerin and vascular calcification among patients with different stages of diabetic nephropathy, but serum FGF23 levels were elevated in those with stage 4 diabetic nephropathy. Simple regression analysis showed that serum osteoprotegerin levels had significant positive correlations with age, systolic blood pressure and serum adiponectin levels, and significant negative correlations with BMI and serum 25-hydroxyvitamin D3.These findings suggest that elevated serum osteoprotegerin may be involved in vascular calcification independently of progression of diabetic nephropathy in patients with type 2 diabetes.Atherosclerosis, macroangiopathy and microangiopathy are major prognostic factors in diabetes. Vascular endothelial impairment is the initial pathological change and is profoundly involved in development of atherosclerosis [1-4]. Progression of diabetic nephropathy, including microalbuminuria, is a risk factor for atherosclerosis in type 2 diabetes mellitus [5,6] and diabetic patients with advanced nephropathy (particularly those on dialysis with end-stage kidney disease) often have vascular calcification [7-10]. However, the duration of diabetes mellitus is not closely related to the extent of vascular calcification, and this condition may be more strongly related to biochemical changes.The RANK/RANKL
Critical Core Masses for Gas Giant Formation with Grain-Free Envelopes
Yasunori Hori,Masahiro Ikoma
Physics , 2010, DOI: 10.1088/0004-637X/714/2/1343
Abstract: We investigate the critical core mass and the envelope growth timescale, assuming grain-free envelopes, to examine how small cores are allowed to form gas giants in the framework of the core accretion model. This is motivated by a theoretical dilemma concerning Jupiter formation: Modelings of Jupiter's interior suggest that it contains a small core of < 10 Earth mass, while many core accretion models of Jupiter formation require a large core of > 10 Earth mass to finish its formation by the time of disk dissipation. Reduction of opacity in the accreting envelope is known to hasten gas giant formation. Almost all the previous studies assumed grain-dominated opacity in the envelope. Instead, we examine cases of grain-free envelopes in this study. Our numerical simulations show that an isolated core of as small as 1.7 Earth mass is able to capture disk gas to form a gas giant on a timescale of million years, if the accreting envelope is grain-free; that value decreases to 0.75 Earth mass, if the envelope is metal-free, namely, composed purely of hydrogen and helium. It is also shown that alkali atoms, which are known to be one of the dominant opacity sources near 1500 K in the atmospheres of hot Jupiters, have little contribution to determine the critical core mass. Our results confirm that sedimentation and coagulation of grains in the accreting envelope is a key to resolve the dilemma about Jupiter formation.
Gas Giant Formation with Small Cores Triggered by Envelope Pollution by Icy Planetesimals
Yasunori Hori,Masahiro Ikoma
Physics , 2011, DOI: 10.1111/j.1365-2966.2011.19140.x
Abstract: We have investigated how envelope pollution by icy planetesimals affects the critical core mass for gas giant formation and the gas accretion time-scales. In the core-accretion model, runaway gas accretion is triggered after a core reaches a critical core mass. All the previous studies on the core-accretion model assumed that the envelope has the solar composition uniformly. In fact, the envelope is likely polluted by evaporated materials of icy planetesimals because icy planetesimals going through the envelope experience mass loss via strong ablation and most of their masses are deposited in the deep envelope. In this paper, we have demonstrated that envelope pollution in general lowers the critical core masses and hastens gas accretion on to the protoplanet because of the increase in the molecular weight and reduction of adiabatic temperature gradient. Widely- and highly-polluted envelopes allow smaller cores to form massive envelopes before disc dissipation. Our results suggest that envelope pollution in the course of planetary accretion has the potential to trigger gas giant formation with small cores. We propose that it is necessary to take into account envelope pollution by icy planetesimals when we discuss gas giant formation based on the core-accretion model.
In-situ Accretion of Hydrogen-Rich Atmospheres on Short-Period Super-Earths: Implications for the Kepler-11 Planets
Masahiro Ikoma,Yasunori Hori
Physics , 2012, DOI: 10.1088/0004-637X/753/1/66
Abstract: Motivated by recent discoveries of low-density super-Earths with short orbital periods, we have investigated in-situ accretion of H-He atmospheres on rocky bodies embedded in dissipating warm disks, by simulating quasi-static evolution of atmospheres that connect to the ambient disk. We have found that the atmospheric evolution has two distinctly different outcomes, depending on the rocky body's mass: While the atmospheres on massive rocky bodies undergo runaway disk-gas accretion, those on light rocky bodies undergo significant erosion during disk dispersal. In the atmospheric erosion, the heat content of the rocky body that was previously neglected plays an important role. We have also realized that the atmospheric mass is rather sensitive to disk temperature in the mass range of interest in this study. Our theory is applied to recently-detected super-Earths orbiting Kepler-11 to examine the possibility that the planets are rock-dominated ones with relatively thick H-He atmospheres. The application suggests that the in-situ formation of the relatively thick H-He atmospheres inferred by structure modeling is possible only under restricted conditions; namely, relatively slow disk dissipation and/or cool environments. This study demonstrates that low-density super-Earths provide important clues to understanding of planetary accretion and disk evolution.
Molecular Spintronics
Masashi Shiraishi,Tadaaki Ikoma
Physics , 2011, DOI: 10.1016/j.physe.2011.02.010
Abstract: Molecular spintronics is recognized to as an attractive new research direction in a field of spintronics, following to metallic spintronics and inorganic semiconductor spintronics, and attracts many people in recent decades. The purpose of this manuscript is to describe the history of molecular spintronics by introducing important achievements and to show the current status of this field. In addition, the authors briefly introduce several theories for implementing studies in molecular spintronics.
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