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Topic: Echocardiographic Evaluation of Left Ventricular Systolic and Diastolic Function in Nigerians with Sickle Cell Disease  [PDF]
Hadiza Saidu, Abdulwahab Kabir, Jamila A. Yau, Ahmad M. Yakasai, Umar Abdullahi, Aisha M. Nalado, Baba Maiyaki Musa
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104527
Abstract:
Introduction: Sickle cell disease (SCD) is chronic, inherited haemoglobin disorder, associated with chronic tissue ischemia which may adversely affect any organ system. Chronic anaemia in SCD results in cardiac chamber dilatation with compensatory increase in left ventricular mass and varying degree of diastolic dysfunction that has been a strong independent predictor of mortality in patients with SCD. There is paucity of echocardiographic studies on adults Nigerians with SCD. This study therefore, aimed to assess left ventricular systolic and diastolic function among sickle cell disease patients in Kano State, North-Western Nigeria. Methods: The study was cross-sectional and comparative conducted at the SCD clinic and Medical/outpatient (MOP) clinic of Murtala Muhammad Specialist Hospital (MMSH), on eligible patients aged 13 years and above. One hundred patients with SCD (HbSS) were recruited as the study group while 100 non SCD (HbAA) patients, matched for age and sex served as controls. Left and right atrial and ventricular dimensions, left ventricular (LV) wall thickness, LV mass index and LV contractility variables were obtained. Parameters of LV diastolic function were also evaluated. Results: There were increases in the left atrial and left ventricular dimensions, left ventricular volumes and left ventricular mass (LVM) of the SCD patients. LV ejection fraction was equivalent, though there was evidence of left ventricular diastolic dysfunction in up to 36%. Conclusion: Left ventricular diastolic dysfunction may complicate cases adults with SCD.
Services and participation in Yemen
Aisha M Saeed
Forced Migration Review , 2010,
Abstract: Assessing the needs of refugees and asylum seekers with disabilities has traditionally been much neglected in refugee assistance programmes. Assessments in Yemen have highlighted shortcomings in service provision and enabled local actors to prioritise accordingly.
Identifying Teaching Style: The Case of Saudi College English Language and Literature Teachers
Aisha M. Alhussain
English Language Teaching , 2012, DOI: 10.5539/elt.v5n8p122
Abstract: The purpose of this paper is twofold. The first objective is to give an account of why I set out to study teaching styles, how I carried out and analyzed a questionnaire survey, what results I got, and what the implications of these results are. The intent is to provide teachers with enough information to help them think about how these findings play out in their own classrooms, thus putting them on track to adapt their teaching style to their students' learning style. The second objective is to see if there is any statistically significant correlation between teaching styles and a number of factors, such as age, years of experience, specialty, and student level. Data analysis showed that literature teachers preferred the all-round flexible style, the mixed style, and the official curriculum and big conference styles successively, whereas linguistics teachers preferred the mixed style, the all-round flexible and straight facts styles, and the student-centered and big conference styles consecutively. No statistically significant correlation was found between teaching styles and age, years of experience, and specialty variables. Whereas statistically significant differences were found between level three and the official curriculum teaching style, and between level four and the student-centered teaching style (p< 0.05).
Dynamics of Charged Plane Symmetric Gravitational Collapse
M. Sharif,Aisha Siddiqa
Physics , 2010, DOI: 10.1007/s10714-010-1071-8
Abstract: In this paper, we study dynamics of the charged plane symmetric gravitational collapse. For this purpose, we discuss non-adiabatic flow of a viscous fluid and deduce the results for adiabatic case. The Einstein and Maxwell field equations are formulated for general plane symmetric spacetime in the interior. Junction conditions between the interior and exterior regions are derived. For the non-adiabatic case, the exterior is taken as plane symmetric charged Vaidya spacetime while for the adiabatic case, it is described by plane Reissner-Nordstr$\ddot{o}$m spacetime. Using Misner and Sharp formalism, we obtain dynamical equations to investigate the effects of different forces over the rate of collapse. In non-adiabatic case, a dynamical equation is joined with transport equation of heat flux. Finally, a relation between the Weyl tensor and energy density is found.
Singularity in Gravitational Collapse of Plane Symmetric Charged Vaidya Spacetime
M. Sharif,Aisha Siddiqa
Physics , 2010, DOI: 10.1142/S0217732310033864
Abstract: We study the final outcome of gravitational collapse resulting from the plane symmetric charged Vaidya spacetime. Using the field equations, we show that the weak energy condition is always satisfied by collapsing fluid. It is found that the singularity formed is naked. The strength of singularity is also investigated by using Nolan's method. This turns out to be a strong curvature singularity in Tipler's sense and hence provides a counter example to the cosmic censorship hypothesis.
Emerging Evidence for MicroRNAs as Regulators of?Cancer Stem Cells
Aisha Sethi,Lynette M. Sholl
Cancers , 2011, DOI: 10.3390/cancers3043957
Abstract: Cancer stem cells are defined as a subpopulation of cells within a tumor that are capable of self-renewal and differentiation into the heterogeneous cell lineages that comprise the tumor. Many studies indicate that cancer stem cells may be responsible for treatment failure and relapse in cancer patients. The factors that regulate cancer stem cells are not well defined. MicroRNAs (miRNAs) are small non-coding RNAs that regulate translational repression and transcript degradation. miRNAs play a critical role in embryonic and inducible pluripotent stem cell regulation and emerging evidence supports their role in cancer stem cell evolution. To date, miRNAs have been shown to act either as tumor suppressor genes or oncogenes in driving critical gene expression pathways in cancer stem cells in a wide range of human malignancies, including hematopoietic and epithelial tumors and sarcomas. miRNAs involved in cancer stem cell regulation provide attractive, novel therapeutic targets for cancer treatment. This review attempts to summarize progress to date in defining the role of miRNAs in cancer stem cells.
Effect of Ajowan Seeds as Safe Inhibitor on the Corrosion of Steel in 2.0 M Sulfuric Acid
Aisha M. Al-Turkustani
Modern Applied Science , 2010, DOI: 10.5539/mas.v4n10p52
Abstract: Corrosion inhibition of steel in sulphuric acid by aqueous extract of Ajowan (carom) seeds has been studied using chemical (HE and ML) and electrochemical (EIS and PDP) measurements at 30?C. The results indicated that Ajowan extract inhibit the corrosion process in 2.0M H2SO4 and the inhibition efficiency increase as concentration increased. Impedance studies showed that the charge transfer controls the dissolution mechanism of steel across the phase boundary in the absence and the presence of the inhibitor and potentiodyanaic polarization results indicate that Ajowan seeds act as mixed type inhibitor. The inhibition efficiency obtained from various employed methods is approximately in good agreement. Adsorption process of Ajowan molecules on steel surface is spontaneous and it obeys the Friuendlish adsorption isotherm.
2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile
Nawal Mishriky,Aisha M. Moustafa
Molbank , 2013, DOI: 10.3390/M794
Abstract: 2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile ( 4) was synthesized via nucleophilic substitution reaction of 1-methylpiperazine with 2-bromo analogue 3. The latter was obtained through bromination (Br 2/AcOH) of 2-[3-oxo-1-phenyl-3-(thiophen-2-yl)propyl]malononitrile ( 2).
An Analysis of Multi-dimensional Gender Inequality in Pakistan
Abdul Hamid,Aisha M. Ahmed
Asian Journal of Business Management , 2011,
Abstract: Women make almost half of the population of Pakistan. They also contribute significantly to economic and social growth. However, in developing countries like Pakistan, women usually suffer from multidimensional inequality of opportunities leading to multidimensional poverty. The dimensions of family, women identity, health, education and women access to economic resources and employment contribute significantly to the discrimination of women. The provision of more opportunities to women in the form of education, better health, possession of assets, provision of credit , employment opportunities and political empowerment starts a ‘virtuous cycle’ for their family and for the overall nation. This paper aims to analyze the multi-dimensional gender inequalities faced by women in the socio-economic and political scenario of Pakistan. To reduce overall inequality along with gender disparities has been a serious challenge for most of the developing countries including Pakistan.
Antimicrobial Activity of Cannabis sativa L.  [PDF]
Esra M. M. Ali, Aisha Z. I. Almagboul, Salwa M. E. Khogali, Umelkheir M. A. Gergeir
Chinese Medicine (CM) , 2012, DOI: 10.4236/cm.2012.31010
Abstract: The oil of the seeds, petroleum ether and methanol extracts of the whole plant of Cannabis sativa belonging to the family Cannabinaceae were screened for their antimicrobial activity against two Gram positive organisms (Bacillus subtilis, Staphylococcus aureus), two Gram negative organisms (Escherichia coli, Pseudomonas aeruginosa) and two fungi namely Aspergillus niger and Candida albicans using the cup plate agar diffusion method. The oil of the seeds of Cannabis sativa exerted pronounced antibacterial activity (21 - 28 mm) against Bacillus subtilis and Staphylococcus aureus, moderate activity (15 mm) against Escherichia coli and high activity (16 mm) against Pseudomonas aeruginosa and inactive against the two fungi tested. The petroleum ether extract of the whole plant exhibited pronounced antibacterial activity (23 - 28 mm) against both Bacillus subtilis and Staphylococcus aureus organisms, high activity (16 mm) against Escherichia coli and inactive against Pseudomonas aeruginosa and both fungi. The methanol extract of the whole plant showed also pronounced antibacterial activity (29 mm) against Bacillus subtilis, low activity (12 mm) against Staphylococcus aureus and high activity (16 - 18 mm) against both Gram negative organisms, inactive against Aspergillus niger and low activity (13 mm) against Candida albicans. The minimum inhibitory concentrations of Cannabis sativa methanol extracts of the seeds and the whole plant against the standard organisms were determined using the agar plate dilution method. The standard organisms were tested against reference antibacterial and antifungal drugs and the results were compared with the activity of the extracts.
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