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Search Results: 1 - 10 of 1885 matches for " Ahmet Buyukdevrim "
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The role of mediastinal adipose tissue 11β-hydroxysteroid d ehydrogenase type 1 and glucocorticoid expression in the development of coronary atherosclerosis in obese patients with ischemic heart disease
Fatmahan Atalar, Selcuk Gormez, Baris Caynak, Gokce Akan, Gamze Tanriverdi, Sema Bilgic-Gazioglu, Demet Gunay, Cihan Duran, Belhhan Akpinar, Ugur Ozbek, Ahmet Buyukdevrim, Zeliha Yazici
Cardiovascular Diabetology , 2012, DOI: 10.1186/1475-2840-11-115
Abstract: Our objective was to evaluate the role of EAT and MAT 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) and glucocorticoid receptor (GCR) expression in comparison with subcutaneous adipose tissue (SAT) in the development of coronary atherosclerosis in obese patients with coronary artery disease (CAD), and to assess their correlations with CD68 and fatty acids from these tissues.Expression of 11β-HSD-1 and GCR was measured by qRT-PCR in EAT, MAT and SAT of thirty-one obese patients undergoing coronary artery bypass grafting due to CAD (obese CAD group) and sixteen obese patients without CAD undergoing heart valve surgery (controls). 11β-HSD-1 and GCR expression in MAT were found to be significantly increased in the obese CAD group compared with controls (p?<?0.05). In the obese CAD group, 11β-HSD-1 and GCR mRNA levels were strongly correlated in MAT. Stearidonic acid was significantly increased in EAT and MAT of the obese CAD group and arachidonic acid was significantly expressed in MAT of the obese male CAD group (p?<?0.05).We report for the first time the increased expression of 11β-HSD-1 and GCR in MAT compared with EAT and SAT, and also describe the interrelated effects of stearidonic acid, HOMA-IR, plasma cortisol and GCR mRNA levels, explaining 40.2% of the variance in 11β-HSD-1 mRNA levels in MAT of obese CAD patients. These findings support the hypothesis that MAT contributes locally to the development of coronary atherosclerosis via glucocorticoid action.In obesity, fat depots localized around the heart are reported to contribute to the pathogenesis of coronary artery disease (CAD) [1-3]. Epicardial adipose tissue (EAT) generates various bioactive molecules which significantly affect cardiac function, and their association with the severity of CAD was has also been reported [2,4]. Human and animal studies have demonstrated EAT is located near to the arteries and that segments of an artery surrounded by EAT develop atherosclerosis faster than the intra-m
Mathematical Modelling in Placing of Fresh Concrete  [PDF]
Ahmet Bilgil
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.33023
Abstract: The main problem in working with fresh concrete is the aggregate segregation during filling of formwork. The segregation is strongly related to W/C (Water/Cement) ratio. The fresh concrete is usually considered as a Non-Newtonian fluid since it is a mixture of aggregate, cement and water. The flow behavior of the fresh concrete to W/C ratio plays a crucial role in the quality of the high performance concretes by affecting the flow behavior of the fresh concrete. The aggregates in the fresh concrete usually cause segregation in the final product depending on the flow condition. In this study, the mechanism of segregation in such systems was theoretically investigated. The mould filling of fresh concrete was numerically investigated and aggregates were considered as Lagrangian particles and segregation was identified from trajectories of such particles. It was found that the aggregates were trapped at the dead zones leading to segregation in the system. The particle size and geometry of the mould was found to have significantly affect the segregation in the system.
Effect of Low Velocity Impact Damage on Buckling Properties  [PDF]
Ahmet YAPICI, Mehmet METIN
Engineering (ENG) , 2009, DOI: 10.4236/eng.2009.13019
Abstract: The work described herein consists of experimental measurement of the post-impact buckling loads of E- glass/epoxy laminates. Composite samples with stacking sequence of [+45/?45/90/0]2s were subjected to low-velocity impact loading at energy levels of 36, 56.13, 79.95, 110.31 and 144 J. The impact tests were conducted with a specially developed vertical drop weight testing machine. Impact parameters like peak load, absorbed energy, deflection at peak load and damage area were evaluated and compared. Damaged specimens were subjected to compressive axial forces and buckling loads of the specimens were obtained. The relation between energy levels and buckling loads is investigated.
Magnetic Oil Thermal Behavior under Electromagnetic Induction for Energy Efficient Heating System Design  [PDF]
Ahmet Kucukkomurler, Ramazan Selver
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2010, DOI: 10.4236/jemaa.2010.25038
Abstract: This study describes thermal behavior of magnetic lubricant oil under electromagnetic induction. Experimental set up include oil pump, oil tank, induction heating unit, and heat exchanger. It is a closed loop system where the oil pump circulates oil through oil tank to the system, at the same time induction heating unit heats up to the heat exchanger where the lubricant oil thermal behavior is examined. The unit has been largely studied and tested both magnetic and regular motor oil in a laboratory environment and promising results have been obtained for an actual indoor floor to space heating system design.
Breathing Intolerance Index in COPD and Obesity: A Comparative Observational Study  [PDF]
Ahmet Baydur, Zhanghua Chen
Open Journal of Respiratory Diseases (OJRD) , 2013, DOI: 10.4236/ojrd.2013.33019
Abstract: Background: The breathing intolerance index, BIT, a noninvasive derivation of the tension-time index of respiratory muscles, has been recently used to evaluate patients with respect to their need for noninvasive ventilation. Comparing the BIT index in different disorders with mild to moderate respiratory impairment, such as COPD and obesity, would be useful in determining differences in threshold for respiratory muscle fatigue amongst cohorts. Objectives: The purpose of this study was to compare control of ventilation and BIT in individuals with obesity, chronic obstructive pulmonary disease (COPD), and control subjects free of cardiorespiratory disorders. Because change in posture can alter respiratory load and control of ventilation, variables were assessed in two postures. Methods: We assessed 142 subjects consisting of 81 with obesity, 42 with COPD, and 19 non-smoking healthy adults. All subjects underwent evaluation of pulmonary function, control of ventilation and BIT index [(Ti/Ttot) × (Vt/FVC)] in seated and supine postures. Findings: BIT index was significantly greater in seated posture in all 3 cohorts due primarily to an increase in Vt in this position. BIT index was similar in value amongst cohorts in both postures, but tended to be higher in patients with obesity and COPD. Conclusion: While BIT index is higher in seated posture, and tends to be higher in patients with obesity and COPD as compared to control subjects, discrimination between cohorts is not found in our study because of small inter-group variations of respiratory function amongst cohorts. Thus, in clinically stable patients whose vital capacities are mild to moderately reduced, the BIT index alone cannot be recommended as a predictive guide for initiating assisted ventilation for respiratory failure. Nevertheless, because it is easy to perform, and is comfortably tolerated by patients, its potential usefulness may be in periodic measurements to monitor its increase as respiratory reserve declines.
Solving Water Problems of a Metropolis  [PDF]
Ahmet Mete Saatci
Journal of Water Resource and Protection (JWARP) , 2013, DOI: 10.4236/jwarp.2013.54A002
Abstract:

The metropolis of Istanbul has faced water supply challenges throughout history; however the situation escalated in the past decade with rapid population growth. Water demand of an ever-growing city could only be solved by transporting water from surrounding water basins as far as 190 km away from the city border. Moreover, imbalanced distribution of water resources and imbalanced water demand on the European and Asian side of the city was resolved by transporting water from Asian side to the European side, by laying water transmission pipes under the Bosphorus Strait and by constructing a tunnel passing 130 m under the Strait. Another difficulty that required challenging solutions was the protection of water reservoirs of the city, hence illegal settlements arose in the reservoir watershed zones due to fast urban growth and migration from rural areas. Discharge of wastewater from illegal settlements caused not only algae growth in water treatment plant (WTP) of one of the largest reservoirs of Istanbul, but also eventual death of algae was a major setback due to anaerobic conditions created in the reservoir. The problem was solved by tertiary treatment of the wastewater and by diverting the effluent through a tunnel away from the reservoir. The aim of this paper is to provide an insight into setbacks faced in a metropolis of 14 million and technical solutions provided against the pollution of reservoirs.

Emotion Regulation Strategies as a Predictor of Life Satisfaction in University Students  [PDF]
Ahmet Yi?it, Ahmet Rag?p ?zpolat, Mehmet Kandemir
Psychology (PSYCH) , 2014, DOI: 10.4236/psych.2014.56062
Abstract:

The goal of this research is to analyze the predictive power level of parent educational background, parent profession and suppression and reappraisal strategies, which are the emotion regulation strategies, on life satisfaction of individuals. Multiple Linear Regression model is used in the study whose research group is made of 422 students from a University, which has a total of 28,000 students, situated in the East of Turkey. Students in the research group are from different grades and demographic features. “Emotion Regulation Scale”, “Satisfaction with Life Scale”, and “Personal Information Form” are used in gathering the data of the research.

The Improvements of the Backhoe-Loader Arms  [PDF]
Ahmet Erklig, Eyüp Yeter
Modeling and Numerical Simulation of Material Science (MNSMS) , 2013, DOI: 10.4236/mnsms.2013.34020
Abstract:

In this study, static structural analysis of backhoe-loader arms has been performed with the finite element method (FEM). The aim of this study is to simulate and strengthen the back and front arms of the backhoe-loader concerning with stress under maximum loading condition and different boundary conditions. According to analysis result, back and front arms of the backhoe-loader are strengthened with the use of reinforcements. As a result of the study, strength of the arms has been increased by nearly 20%.

Improved Artificial Bee Colony Algorithm for Continuous Optimization Problems  [PDF]
Mustafa Servet Kiran, Ahmet Babalik
Journal of Computer and Communications (JCC) , 2014, DOI: 10.4236/jcc.2014.24015
Abstract:

The artificial bee colony (ABC) algorithm is a swarm-based metaheuristic optimization technique, developed by inspiring foraging and dance behaviors of honey bee colonies. ABC consists of four phases named as initialization, employed bee, onlooker bee and scout bee. The employed bees try to improve their solution in employed bees phase. If an employed bee cannot improve self-solution in a certain time, it becomes a scout bee. This alteration is done in the scout bee phase. The onlooker bee phase is placed where information sharing is done. Although a candidate solution improved by onlookers is chosen among the employed bee population according to fitness values of the employed bees, neighbor of candidate solution is randomly selected. In this paper, we propose a selection mechanism for neighborhood of the candidate solutions in the onlooker bee phase. The proposed selection mechanism was based on information shared by the employed bees. Average fitness value obtained by the employed bees is calculated and those better than the aver- age fitness value are written to memory board. Therefore, the onlooker bees select a neighbor from the memory board. In this paper, the proposed ABC-based method called as iABC were applied to both five numerical benchmark functions and an estimation of energy demand problem. Obtained results for the problems show that iABC is better than the basic ABC in terms of solution quality.

The Impact of Sincerity of Terrorists on Committing Terrorist Activities in Turkey  [PDF]
Ahmet Turer, Robyn Diehl McDougle
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.39034
Abstract: Research Summary: This study explores the impact of sincerity of terrorists on committing terrorist activities in Turkey. One of the researchers is a Chief of Police in Turkey and has worked in the Anti-terror Department for a considerable part of his professional career. His professional experience has shown that the more sincere a terrorist is the more violent or heedless the terrorist activity is. Thus this research academically and statistically examines this observation and finds that sincerity affects the level of violence. Attachment and adherence to the terrorist organization turn even the characteristically non-violent people into blood seeking terrorists. Policy Implications: Terrorism is still one of the major challenges that the contemporary world faces today. Governments, policy makers, and other stakeholders have great difficulty identifying effective legal mechanisms for fighting terrorism, mainly because of uncertainties regarding both the targets and offenders of terrorist acts. The current study suggests two types of policy implementations. The first is to improve socioeconomic conditions so that people will be less vulnerable to terrorist recruitment, a tactic that requires the identification of risk groups. The second is to detect terrorists and their networks, a tactic that requires the use of different types of intelligence and preventive interventions in the locations that terrorists primarily use for recruitment. The former implementation is a long-term and large-scale project, whereas the latter one is a short-term, small-scale project that appears to be more promising. The two are, however, interrelated. Simply implementing the second tactic could prevent terrorism, but in the absence of the first tactic, terrorist groups will likely find other fertile ground in which to flourish.
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