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Search Results: 1 - 10 of 9363 matches for " Ahmed Bayoumi "
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Synthesis and thermal studies of mixed ligand complexes of Cu(II), Co(II), Ni(II) and Cd(II) with mercaptotriazoles and dehydroacetic acid  [PDF]
Dina M. Fouad, Ahmed Bayoumi, Mohamed A. ElGahami, Said A. Ibrahim, Abbas M. Hammam
Natural Science (NS) , 2010, DOI: 10.4236/ns.2010.28103
Abstract: A series of new mixed ligand complexes of cobalt(II), nickel(II), copper(II) and cadmium(II) have been synthesized with 3benzyl1H4[(2 methoxybenzylidine) amino]1, 2, 4triazole5 thione (MBT), 3bezyl1H4[(4chlorobenzylidine) amino]1, 2, 4triazole5thione (CBT), 3benzyl 1H4[(4nitrobenzylidine)amino]1, 2, 4triazole 5thione (NBT) and dehydroacetic acid sodium salt (Nadha). The mixed ligand complexes have been characterized by elemental analysis, spec troscopic spectral measurements (IR, UVVis.), molar conductance, magnetic measurements and thermal studies. The stoichiometry of these com plexes is M:L1:L2 = 1:1:1, 1:2:1 or 1:1:2 where L1 = NBT, CBT and MBT and L2 = Nadha. Tetrahedral structure was proposed for all Cd(II) mixed ligand complexes while the square planar geometry was proposed for Cu(II) mixed ligand complex with NBT. Octahedral structure was proposed for Ni(II), Co(II) mixed ligand complexes and Cu(II) mixed ligand complexes with CBT and MBT ligands. The thermal decomposition study of the prepared complexes was monitored by TG, DTG and DTA analysis in dynamic nitrogen atmosphere. TG, DTG and DTA studies confirmed the chemical formulations of theses complexes. The kinetic parameters were determined from the the thermal decomposition data using the graphical methods of CoatsRedfern and HorwitzMetzger. Thermodynamic parameters were calculated using standard relations.
Compatibility of Biomphalaria glabrata and B. alexandrina snails to infection with an egyptian strain of Schistosoma mansoni through two cycles in the experimental final host  [PDF]
Momeana Bayoumi Mahmoud
Advances in Biological Chemistry (ABC) , 2011, DOI: 10.4236/abc.2011.13012
Abstract: The infection rate and cercarial production from B. glabrata, in comparison with B. alexandrina snails, post their exposure to S. mansoni miracidia of an E- gyptian strain after two cycles in albino-mice was stu-dies.The results indicated that infection rate of B. glabrata with the Egyptian strain of S. mansoni was less than that of B. alexandrina snails On the other hand infected B. glabrata exhibited a longer life span and a higher number of shedding cercariae, It was also, noticed that in the first cycle mice infected with S. mansoni cercariae shed from infected B. alexandrina snails, the mean number of worms recovered from infected mice was approximately twice that in mice infected with cercariae shed from infected B. glabrata snails The same observation was recorded from the mean number of ova/g liver tissue from infected mice. In the second cycle the same observation was recorded as first cycle suppression in the infection rate of B.glabrata than that B.alexandrina. Also, longer pre-patent period and life span Also, mice infection as the number of worms per infected mouse by cercariae shed from B.alexandrina snails was approximately 2.5 times that of mice infected by cercariae shed from B. glabrata being 29.3 and 12.5 worms/mouse.The results also indicated that the egg laying capacity of B. glabrata was higher than that B. alexandrina, It is concluded from this work that infectivity of S. man-soni cercariae shed from B. glabrata snails after two cycles of mice infection and used to infect the experi-mental final host was less than that of cercariae shed from infected B. alexandrina snails. This may declare a low compatibility of B. glabrata snails with the Egyptian strain of S. mansoni in comparison with B. alexandrina snails. However, this conclusion needs more passages of mice infection with cercariae to have precise data and conclusions.
Antiproliferative Properties of Vinyl Dipeptides: Synthesis and MCF-7 Cell Line Testing  [PDF]
Ashraf Hassan Bayoumi
Open Journal of Medicinal Chemistry (OJMC) , 2012, DOI: 10.4236/ojmc.2012.24013
Abstract: Peptide mimics derived with close structure to peptide have vast utility because they are expected to interfere with biological targets while having superior drug-like properties if compared to peptides. In this work, novel vinyl dipeptides which are different in a double bond between the α-carbon of peptide and C1 of its side chain. Added to that, suitable substituents were selected to harness drug-like properties. The compounds were found to have moderate activities when tested against MCF-7 breast cancer cell line. For instance, the adamantyl analogue 2-(benzoylamino)-3-(2-furyl)-N-(1-adamantyl) propenamide (1c) and the heterocyclic analogue 2-(Benzoylamino)-3-(2-furyl)-N-[2-(5-cyanothia-zol-2-yl)] propenamide (1o) exhibited inhibition potency at 27.4 and 37.8 μM, respectively.
Subjective Burden on Family Carers of Hemodialysis Patients  [PDF]
Magda M. Bayoumi
Open Journal of Nephrology (OJNeph) , 2014, DOI: 10.4236/ojneph.2014.42011

Background: Hemodialysis (HD) is an important objective burden (task) on patient with end stage renal disease (ESRD) and the caregiver has a subjective burden which contributes to lifestyle changes, which result in depression, anxiety declining physical health, social isolation and financial strain. Aim: To evaluate the subjective burden on family caregiver who cares patient on maintenance hemodialysis therapy. Methods: Fifty main family caregivers for each patient on HD and the instrument were used by Caregiver Burden Interview (CBI) completed by caregiver as a major of subjective response to care giving. Results: The present study findings demonstrated that main age of caregiver was 40 (11.0) years, two thirds of females, and they were mostly married (78.0%) with children. The total family caregiver burden reported was 43.3 (21.7), role strain 50.0 (25.4) and the personal strain 39.5 (19.7). The total caregivers’ burden significantly positively correlated with the patients’ age (r = 0.461) and negatively correlated with patients’ level of education (r = ?0.290). Moreover the role strain, personal strain and total caregiver burden scores were statistically and significantly negatively correlated with their age (r = ?0.444) and level of education (r = ?0.416) and the total burden scores were ranked as moderately to severely burdened all family caregivers. Conclusion: Caregivers’ appraisal, coping strategies, interpersonal relationship issues, and social support would need to be considered for caregivers of patients maintained on HD.

Low Dose Total Body Irradiation for Relapsed Low Grade Non-Hodgkin’s Lymphoma: Experience of National Cancer Institute, Cairo  [PDF]
Yasser Bayoumi, Aida Radwan
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.61004

Background and Purpose: The relapsed low grade non-Hodgkin’s lymphoma (LG-NHL) is currently incurable disease and the optimal treatment regimen has not determined yet. Low dose total body irradiation (LTBI) provides an alternative mechanism of action against cancer cells rather than direct cell kill. The mode of action of LTBI is immune-modulatory effect, induction of apoptosis and hypersensitivity to low radiation doses. The aim of our study is to evaluate the effect of LTBI on relapsed LG-NHL and reporting our experience at National Cancer Institute, Cairo (NCI, Cairo). Material and Methods: Fifty eight patients with relapsed LG-NHL and received LTBI studied retrospectively. LTBI dose was 1.6 Gy/8 fractions divided on 2 courses; each course 4 fractions treated over 4 days with 2 weeks rest between the 2 courses. Results: The median age is 54 years; 65% of the patients are men. Forty (69%) patients had performance status of 2 or more. Twenty seven patients were stage II/III and 31 patients (53%) had stage IV disease. Twenty six (45%) patients had bulky disease more than 10 cm and 22 (38%) patients had B symptoms at the time of relapse. The extranodal disease was present in 17 patients (29%) and 78% of the patients received >3 regimens of chemotherapy before referral to LTBI. Twenty three patients received IFRT (mean dose 32 ± 4 Gy) to initially bulky sites after LTBI. Fourteen patients (24%) achieved complete remission (CR) while 45%, 21% and 10% had partial remission (PR), stable disease (SD) and progressive disease (PD) respectively. The median PFS duration was 14 months and the median OS duration was 39 months. Stage VI, >3 regimen of chemotherapy and bad response to LTBI (SD) affected progression duration adversely (0.03, 0.05 and 0.01 respectively). The response to LTBI is the only factor affected the OS duration significantly. The 3-year PFS was 19% ± 9%, and 3-year OS was 45% ± 8%. Stage IV was the only factor affected the 3-year PFS significantly with p value 0.03. The hematological toxicity was the main side effect of LTBI. Eleven patients developed G3/4 anemia while 8 patients only developed G3/4 thrombocytopenia and 13 patients developed G3/4 leucopenia. Conclusion: The use of LTBI in patients with relapsed low

Exploring disability from the perspective of adults living with HIV/AIDS: Development of a conceptual framework
Kelly K O'Brien, Ahmed M Bayoumi, Carol Strike, Nancy L Young, Aileen M Davis
Health and Quality of Life Outcomes , 2008, DOI: 10.1186/1477-7525-6-76
Abstract: We conducted four focus groups and 15 face-to-face interviews with 38 adults living with HIV. We asked participants to describe their health-related challenges, their physical, social and psychological areas of life affected, and impact on their overall health. We analyzed data using grounded theory techniques. We also conducted two validity check focus groups with seven returning participants.Disability was conceptualized by participants as multi-dimensional and episodic characterized by unpredictable periods of wellness and illness. The Episodic Disability Framework consisted of three main components: a) dimensions of disability that included symptoms and impairments, difficulties carrying out day-to-day activities, challenges to social inclusion, and uncertainty that may fluctuate on a daily basis and over the course of living with HIV, b) contextual factors that included extrinsic factors (social support and stigma) and intrinsic factors (living strategies and personal attributes) that may exacerbate or alleviate disability, and c) triggers that initiate momentous or major episodes of disability such as receiving an HIV diagnosis, starting or changing medications, experiencing a serious illness, and suffering a loss of others.The Episodic Disability Framework considers the variable nature of disability, acknowledges uncertainty as a key component, describes contextual factors that influence experiences of disability, and considers life events that may initiate a major or momentous episode. This framework presents a new way to conceptualize disability based on the experience of living with HIV.Since the introduction of combination antiretroviral therapy, in developed countries HIV increasingly is perceived as a long-term illness in which individuals experience complications of both the disease and its associated treatments [1]. Characterizing such challenges, which may be termed disability, is necessary for a comprehensive evaluation of the experience of living w
Investigations on the Chemical Degradation of Silver Gelatine Prints
Maha Ahmed ALI,Mona Fouad ALI,Mohammed Osama SAKER,Abdel Azez El Bayoumi ABDEL ALEEM
International Journal of Conservation Science , 2012,
Abstract: Photographs are considered composite objects with complex chemical and physical structures. Therefore they are more prone to damage as compared to other objects. Chemical degradation is by far the most common decay form found among photographic collections. This study investigates the chemical degradation of silver gelatin prints (DOP) and the reaction of the image, silver, gelatin, and paper to accelerated aging, to the action of light, and oxidizing gases, in terms of their physical and chemical nature. The test materials used are properly washed and poorly washed grayscale, black-and-white processed images on photographic paper (Black & White Photographic Paper BH 0 Bromofort 6P0661 Tropical from Forte Photochemical Company Vác, Hungary). After exposure, the results were studied by means of visual inspection, amino acid analyzer, Fourier transform infrared and transmission electron microscope. The results were compared with those of the control samples. Our study revealed that the image, silver, gelatin and photographic paper are greatly affected by oxidizing agents and that the effect increased if the photographic prints were inadequately washed at the time of their processing. Furthermore, our results indicated that an increased amount of ammonia and amino acid in the silver gelatin print is a reliable indicator of the degradation of its gelatine emulsion.
Steroid-Resistant Extranodal Rosai-Dorfman Disease of Cheek Mass and Ptosis Treated with Radiation Therapy
Ahmed Marzouk Maklad,Yasser Bayoumi,Mutahir Tunio,Wafaa AlShakweer,Mashooque A. Dahar,Shomaila A. Akbar
Case Reports in Hematology , 2013, DOI: 10.1155/2013/428297
Abstract: Background. Rosai-Dorfman Disease (RDD) is rare benign hematologic disorder of histiocytes, which usually manifests as painless lymphadenopathy, fever, leukocytosis and hypergammaglobulinemia. Extranodal RDD has been reported in 43% of cases, with skin as commonly involved site followed by head and neck region. However, soft tissue cheek mass is rare presentation of extra-nodal RDD. Case Presentation. A 26-year-old Saudi man presented with a six-month history of right cheek swelling and left upper eyelid swelling. Physical examination revealed right cheek mass of size ?cm and left upper eyelid mass of size ?cm and no palpable cervical lymphadenopathy. Incisional biopsy of cheek mass showed positivity for S100 and negativity for CD1a, consistent with extra-nodal RDD. Patient did not respond to systemic steroids and was given radiation therapy to left orbit with minimal response. Then, he was started on chemotherapy Rituximab, cyclophosphamide, vincristine, and prednisolone (RCVP) 8 cycles followed by reirradiation 10?Gy in 10 fractions with 6?MeV electron with complete response. After 12 months of followup, patient had recurrence in right cheek and was started on radiotherapy to the cheek mass. Conclusion. Extra-nodal RDD with involvement of cheek is a rare presentation. Incorporation of S100 and CD1a is helpful in diagnoses of RDD and differentiating it from other benign histiocytosis. Treatment consists of surgery, steroids, chemotherapy, and radiation therapy. 1. Introduction Rosai-Dorfman Disease (RDD) is also referred to as sinus histiocytosis with massive lymphadenopathy (SHML), which is rare, benign, and self-limited and is a non-Langerhans proliferative disorder of histiocytes [1]. It is clinically characterized by painless cervical lymphadenopathy, fever, anemia, leukocytosis, elevated erythrocyte sedimentation rate (ESR), and a polyclonal hypergammaglobulinemia [2]. It may affect any age group or any gender and without racial predilection; however, 80% of the patients are aged 20 years or younger at onset [3]. Extranodal RDD has been reported in 43% of cases, and the skin is the most common extranodal site [4]. However, when the disease is confined to the skin, it is classified as cutaneous Rosai-Dorfman disease (CRDD). The skin lesions have variable forms, ranging from single papules to psoriasiform, xanthomatous, acneiform, vasculitis-like, and pseudotumor-like multiple nodules and plaques; any part of the body may be affected, but more common in head and neck region [5]. Herein we presented 26-year-old Saudi man, who present with RDD of
Finite Iterative Algorithm for Solving a Complex of Conjugate and Transpose Matrix Equation
Mohamed A. Ramadan,Talaat S. El-Danaf,Ahmed M. E. Bayoumi
Journal of Discrete Mathematics , 2013, DOI: 10.1155/2013/170263
Abstract: We consider an iterative algorithm for solving a complex matrix equation with conjugate and transpose of two unknowns of the form: + . With the iterative algorithm, the existence of a solution of this matrix equation can be determined automatically. When this matrix equation is consistent, for any initial matrices , the solutions can be obtained by iterative algorithm within finite iterative steps in the absence of round-off errors. Some lemmas and theorems are stated and proved where the iterative solutions are obtained. A numerical example is given to illustrate the effectiveness of the proposed method and to support the theoretical results of this paper. 1. Introduction Consider the complex matrix equation: where , , , and are given matrices, while are matrices to be determined. In the field of linear algebra, iterative algorithms for solving matrix equations have received much attention. Based on the iterative solutions of matrix equations, Ding and Chen presented the hierarchical gradient iterative algorithms for general matrix equations [1, 2] and hierarchical least squares iterative algorithms for generalized coupled Sylvester matrix equations and general coupled matrix equations [3, 4]. The hierarchical gradient iterative algorithms [1, 2] and hierarchical least squares iterative algorithms [1, 4, 5] for solving general (coupled) matrix equations are innovational and computationally efficient numerical ones and were proposed based on the hierarchical identification principle [3, 6] which regards the unknown matrix as the system parameter matrix to be identified. Iterative algorithms were proposed for continuous and discrete Lyapunov matrix equations by applying the hierarchical identification principle[7]. Recently, the idea of the hierarchical identification was also utilized to solve the so-called extended Sylvester-conjugate matrix equations in [8]. From an optimization point of view, a gradient-based iteration was constructed in [9] to solve the general coupled matrix equation. A significant feature of the method in [9] is that a necessary and sufficient condition guaranteeing the convergence of the algorithm can be explicitly obtained. Some complex matrix equations have attracted attention from many researchers since it was shown in [10] that the consistence of the matrix equation can be characterized by the consimilarity [11–13] of two partitioned matrices related to the coefficient matrices , and . By consimilarity Jordan decomposition, explicit solutions were obtained in [10, 14]. Some explicit expressions of the solution to the matrix
How do existing HIV-specific instruments measure up? Evaluating the ability of instruments to describe disability experienced by adults living with HIV
Kelly K O'Brien, Ahmed M Bayoumi, Carol Strike, Nancy L Young, Kenneth King, Aileen M Davis
Health and Quality of Life Outcomes , 2010, DOI: 10.1186/1477-7525-8-88
Abstract: We searched databases from 1980 to 2006 for English language, HIV-specific, self-reported questionnaires consisting of at least two items that were tested for reliability and validity. We then conducted a content analysis to assess how well existing questionnaires describe disability as defined by the Episodic Disability Framework, a framework that conceptualizes this experience from the perspective of adults living with HIV. We matched items of the instruments with categories of the framework to evaluate the extent to which the instruments capture major dimensions of disability in the framework.We reviewed 4274 abstracts, of which 30 instruments met the inclusion criteria and were retrieved. Of the four major dimensions of disability, symptoms/impairments were included in all 30 instruments, difficulties with day-to-day activities in 16, challenges to social inclusion in 16, and uncertainty in 9. Seven instruments contained at least 1 item from all 4 dimensions of disability (breadth) however, the comprehensiveness with which the dimensions were represented (depth) varied among the instruments.In general, symptoms/impairments and difficulties carrying out day-to-day activities were the disability dimensions characterized in greatest depth while uncertainty and challenges to social inclusion were less well represented. Although none of the instruments described the full breadth and depth of disability as conceptualized by the Episodic Disability Framework, they provide a foundation from which to build a measure of disability for adults living with HIV.With longer survival, HIV-positive individuals are facing an increasing variety of health-related consequences and symptoms related to HIV infection, associated treatment, and concurrent health conditions [1-11]. Together, these experiences may be conceptualized as disability. We developed a conceptual framework of disability from the perspective of adults living with HIV. In the Episodic Disability Framework, adults l
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