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Search Results: 1 - 10 of 10 matches for " Afua Amankwaa "
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Knowledge about Sexual and Reproductive Health Services and Practice of What Is Known among Ghanaian Youth, a Mixed Method Approach  [PDF]
Jonathan Mensah Dapaah, Seth Christopher Yaw Appiah, Afua Amankwaa, Larbi Rita Ohene
Advances in Sexual Medicine (ASM) , 2016, DOI: 10.4236/asm.2016.61001
Abstract: Most young person will become sexually active before their 20th birthday having to battle with early and unplanned pregnancies, unsafe abortions, maternal deaths and injuries. This study examined young person’s sexual knowledge, attitudes and practices and their levels of utilization of sexual reproductive health. Our study progresses beyond current research of reporting only sexual behaviour among youth to have insight into sexual and reproductive health update drivers yielding new empirically robust results for the Ghanaian case for sexual and reproductive health service uptake. The descriptively cross sectional design was employed in sampling 170 youth (150 surveyed and 20 Interviewed) using the stratified sampling technique together with a purposive selection of one key informant. Test of significance and associations were performed with the Chisquare test. In all 45.2% (77/170) of youth (10 - 24) had had sexual experience in life time. In respect of in-school youth, 42% (63/150) had had sexual experience whiles 70% (14/20) out-of-school youth had had sexual intercourse in life time. A total of 28.8% (49/170) of all the youth had sexual intercourse in the last six months with only 40.1 (20/49) using condom for protection. Parental discussion of contraceptive methods (29.3%) and sexual and romantic relationship (28.0%) was the least sexual and reproductive health area discussed among in-school youth. Youth knowledge of the available sexual reproductive health service was statistically associated with reproductive health service utilization (X2 = 0.00, P ≤ 0.05). A concerted effort is required from government, NGO, Civil society organizations and religious bodies to help translate youth knowledge about sexual health into responsible sexual life and protective sex.
Development of a prompting method to promote adolescent mother/infant verbal interactions using bug-in-the-ear-feedback
Afua Ottie Arhin
Psychology Research and Behavior Management , 2008, DOI: http://dx.doi.org/10.2147/PRBM.S4119
Abstract: pment of a prompting method to promote adolescent mother/infant verbal interactions using bug-in-the-ear-feedback Original Research (4679) Total Article Views Authors: Afua Ottie Arhin Published Date November 2008 Volume 2008:1 Pages 21 - 26 DOI: http://dx.doi.org/10.2147/PRBM.S4119 Afua Ottie Arhin Grambling State University, Grambling, LA, USA Abstract: It has been documented that adolescent mothers are less verbally and emotionally responsive in their interactions with their children compared to adult mothers. These less than optimal adolescent mother/infant interactions have been found to affect the child’s healthy growth and development. This small study aimed to identify and characterize the frequency of verbal behaviors exhibited in the infant/adolescent mother dyad during feeding sessions during a baseline phase of a study that employed single subject methodology. An individualized bug-in-the-ear feedback and prompting parent training model was instituted in the intervention phase of the study to improve the frequency and quality of infant-mother interaction. Results of the study clearly revealed low frequency of verbal interaction in the baseline phase. After a structured prompting intervention was instituted there were positive effects in the mother’s behaviors which in turn positively impacted infant behavior.
Development of a prompting method to promote adolescent mother/infant verbal interactions using bug-in-the-ear-feedback
Afua Ottie Arhin
Psychology Research and Behavior Management , 2008,
Abstract: Afua Ottie ArhinGrambling State University, Grambling, LA, USAAbstract: It has been documented that adolescent mothers are less verbally and emotionally responsive in their interactions with their children compared to adult mothers. These less than optimal adolescent mother/infant interactions have been found to affect the child’s healthy growth and development. This small study aimed to identify and characterize the frequency of verbal behaviors exhibited in the infant/adolescent mother dyad during feeding sessions during a baseline phase of a study that employed single subject methodology. An individualized bug-in-the-ear feedback and prompting parent training model was instituted in the intervention phase of the study to improve the frequency and quality of infant-mother interaction. Results of the study clearly revealed low frequency of verbal interaction in the baseline phase. After a structured prompting intervention was instituted there were positive effects in the mother’s behaviors which in turn positively impacted infant behavior.Keywords: adolescent mothers, verbal interactions, single subject design
Interactions of LC8 with N-Terminal Segments of the Intermediate Chain of Cytoplasmic Dynein
Afua Nyarko,Michael Hare,Moses Makokha,Elisar Barbar
The Scientific World Journal , 2003, DOI: 10.1100/tsw.2003.56
Abstract:
Street-Vended Local Foods Transformation: Case of Hausa Koko, Waakye and Ga Kenkey in Urban Ghana  [PDF]
Joyce Afua Sarpong Haleegoah, Guido Ruivenkamp, George Essegbey, Godfred Frempong, Joost Jongerden
Advances in Applied Sociology (AASoci) , 2016, DOI: 10.4236/aasoci.2016.63009
Abstract: People in Ghana accept various dishes as national foods that originally, were consumed in particular regions and among particular ethnic groups. These foods form part of the national culture and are developed through several processes. National food cultures are developed through a simultaneous process of ethnic specialization and the advancement of national cuisines, which bring into focus the local as well as the national aspects of foods. The approach to this study was case study methodology with different data collecting tools in three cities: Accra, Kumasi and Tamale in Ghana. We developed literature on transformation of food-cultures and showed how the process of migration of people produced cuisines in contemporary Ghana and transformed ethnic dishes into national ones. Through the memories and narratives of female vendors’ knowledge on the preparation and vending skills, these cuisines were transferred to other people. The results showed how local foods continued to exist, how some aspects of local foods had changed, and the underlying cultural migration and the producing food vendors and consumers that influenced food transformation. We concluded that several factors mediated this dynamism in Ghanaian foods.
Metabolic Syndrome among Ischaemic Stroke Patients in Ghana: The Possible Role of Renin and Aldosterone  [PDF]
Francis Agyemang Yeboah, Bernard Nkum, Bright Amankwaa, Benjamin Ackon Eghan Jr., Emmanuel Acheampong, Paul Nsiah, Perditer Okyere, Lawrence Owusu, Emmanuella Batu Nsenba, Enoch Odame Anto
Open Access Library Journal (OALib Journal) , 2017, DOI: 10.4236/oalib.1103952
Abstract:
Background: Both metabolic syndrome (MetSyn) and the Renin Angiotensin Aldosterone System (RAAS) are predictors of adverse outcomes in stroke patients. This study aimed at evaluating the association between RAAS and MetSyn among ischaemic stroke subjects in a tertiary hospital of Ghana from September 2015 to June 2016. Methodology: The study purposively recruited 252 Ghanaians comprising 132 ischaemic stroke patients and 120 apparently healthy control subjects. The participants were subjected to measurements of plasma renin, serum aldosterone, lipid profile, anthropometries and blood pressure. Results: MetSyn prevalence among the stroke subjects compared to the controls were 50.0% vs 8.3% (NCEP/ATP III), 71.2% vs 9.2 (IDF) and 71.2% vs 6.7% (H_MS). Both renin and aldosterone were significantly (p < 0.05) higher in the ischaemic stroke subjects [(1.8 ± 0.1 vs 1.4 ± 0.1) pg/ml and (2.9 ± 0.2 vs 2.3 ± 0.2) pg/ml respectively]. Adjusting for age, gender, diabetes status and hypertension, third tertile (T3) aldosterone (aOR = 2.7, p = 0.008), obesity (aOR = 11.7, p = 0.004) and high triglyceride (aOR = 5.3, p < 0.001) but not renin (aOR = 6.1, p = 0.742) were independently associated with increasing odds of metabolic syndrome. Moreover, there was a significant (p < 0.050) correlation between plasma renin and waist circumference (WC) (r = 0.493) and high density lipoprotein (HDL) (r = ﹣0.319). Significant (p < 0.050) correlations also existed between serum aldosterone and WC (r = 0.588), waist-to-height ratio (WHR) (r = 0.503), body mass index (BMI) (r = 0.691), HDL (r = ﹣0.317), total cholesterol (r = 0.678) and triglyceride (r = 0.439). Conclusion: Aldosterone and not renin could play significant role in the pathophysiology of metabolic syndrome in ischaemic stroke. These findings underpin the observations that aldosterone is associated with several cardiovascular risk factors and may exacerbate metabolic defects in people with ischaemic stroke. Adequate aldosterone blockade could therefore mitigate the development and progression of metabolic syndrome in ischaemic stroke subjects.
ETS Transcription Factors Control Transcription of EZH2 and Epigenetic Silencing of the Tumor Suppressor Gene Nkx3.1 in Prostate Cancer
Paolo Kunderfranco,Maurizia Mello-Grand,Romina Cangemi,Stefania Pellini,Afua Mensah,Veronica Albertini,Anastasia Malek,Giovanna Chiorino,Carlo V. Catapano,Giuseppina M. Carbone
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0010547
Abstract: ETS transcription factors regulate important signaling pathways involved in cell differentiation and development in many tissues and have emerged as important players in prostate cancer. However, the biological impact of ETS factors in prostate tumorigenesis is still debated.
An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model
Afua Mensah, Claire Mulligan, Jackie Linehan, Sandra Ruf, Aideen O'Doherty, Beata Grygalewicz, Janet Shipley, Juergen Groet, Victor Tybulewicz, Elizabeth Fisher, Sebastian Brandner, Dean Nizetic
BMC Developmental Biology , 2007, DOI: 10.1186/1471-213x-7-131
Abstract: We have subcutaneously injected mouse pluripotent ES cells containing a single freely segregating supernumerary human chromosome 21 (HSA21) into syngeneic mice, to generate transchromosomic teratomas. Transchromosomic cells and parental control cells were injected into opposite flanks of thirty mice in three independent experiments. Tumours were grown for 30 days, a time-span equivalent to combined intra-uterine, and early post-natal mouse development. When paired teratomas from the same animals were compared, transchromosomic tumours showed a three-fold lower percentage of neuroectodermal tissue, as well as significantly reduced mRNA levels for neuron specific (Tubb3) and glia specific (Gfap) genes, relative to euploid controls. Two thirds of transchromosomic tumours also showed a lack of PCR amplification with multiple primers specific for HSA21, which were present in the ES cells at the point of injection, thus restricting a commonly retained trisomy to less than a third of HSA21 genes.We demonstrate that a supernumerary chromosome 21 causes Inhibition of Neuroectodermal DIfferentiation (INDI) of pluripotent ES cells. The data suggest that trisomy of less than a third of HSA21 genes, in two chromosomal regions, might be sufficient to cause this effect.Down's syndrome (DS), caused by the trisomy of human chromosome 21 (HSA21), [1] is a complex condition characterized by a plethora of phenotypic features, most striking of which are reduced neuron number and synaptic plasticity, early Alzheimer-like neurodegeneration, craniofacial dysmorphia, heart development defects, and powerful suppression of the incidence of most solid tumours [2,3]. In the first few months of life, DS babies display brachycephaly, microcephaly, delayed myelination, reduced growth of frontal lobes, a narrowing of the superior temporal gyrus, diminished size of the brainstem and cerebellum, and up to 50% reduction in numbers of cortical granular neurons [4-6]. The exact timing of onset of these
Evaluating the Effect of Gamma Radiation on the Total Phenolic Content, Flavonoids, and Antioxidant Activity of Dried Pleurotus ostreatus ((Jacq. ex. Fr) Kummer) Stored in Packaging Materials
Nii Korley Kortei,George Tawia Odamtten,Mary Obodai,Victoria Appiah,Felicia Akuamoa,Afua Kobi Adu-Bobi,Sylvester Nana Yao Annan,Jonathan Nii Okai Armah,Stanley Akwesi Acquah
Advances in Pharmaceutics , 2014, DOI: 10.1155/2014/262807
Abstract: Dried Pleurotus ostreatus mushrooms stored in polythene and polypropylene packs were exposed to gamma radiation from a cobalt-60 source at doses of 0, 0.5, 1, 1.5, and 2?kGy at a dose rate of 1.7?kGy/hr and stored for a period of 1 month. Total phenolic contents, flavonoids, and free radical scavenging activity DPPH (2,2′-diphenyl-1-picrylhydrazyl) were determined using aqueous, ethanol, and methanol extracts by Folin-Ciocaultaeu method as a source of potential natural antioxidants. Total phenol content ranged 0.56 ± 0.01–10.96 ± 1.7?mg/GAE, flavonoids ranged 1.64 ± 0.05–8.92 ± 0.6?mg/QE, DPPH radical scavenging activity also ranged 7.02 ± 0.10–13.03 ± 0.04%, and IC50 values also ranged 0.08–0.16?mg/mL. Statistical differences (P < 0.05) were recorded for the extracts and the treatment doses of mushrooms stored in polythene and polypropylene packs. A significant linear correlation was confirmed between values for the total phenolic content and antioxidant activity of mushroom extracts. The high contents of phenolic compounds indicated that these compounds contribute to high antioxidant activity. Pleurotus ostreatus can be regarded as a promising candidate for natural mushroom sources of antioxidants with high value. The use of low dose gamma radiation by the local food industry could improve the hygienic quality, extend shelf-life, and preserve nutrients and antinutrients. 1. Introduction Phenolic compounds are secondary metabolites that are derivatives of the pentose phosphate, shikimate, and phenylpropanoid pathways in living organisms [1–3]. They act in defense against pathogens, animal mycophage, or fungivore aggression and as response to various abiotic stress conditions, such as rainfall and ultraviolet radiation [4]. Polyphenols have protective activity which has been previously attributed to free radical scavenging, metal chelating properties, capability of inhibiting or reducing different enzymes, such as telomerase [5], cyclooxygenase [6, 7], or lipoxygenase [8, 9], and then most importantly as antioxidant compounds with the ability to trap free radicals and thus inhibit the oxidative mechanisms. However, in more recent years, they play roles such as interacting with signal transduction pathways and cell receptors [10–12]. Naturally occurring antioxidants can be found in whole grains, fruits, vegetables, teas, spices, and herbs. Mushrooms have also been reported as living organisms with antioxidant activity which is correlated with their phenolic and polysaccharide compounds [13–15]. Their global economic value is now incredible, and the
Adherence to Lifestyle Modification among Hypertensive Clients: A Descriptive Cross-Sectional Study  [PDF]
Yaa Obirikorang, Christian Obirikorang, Emmanuel Acheampong, Enoch Odame Anto, Beatrice Amoah, Eva Fosu, Joseph A. Eshiman Amehere, Emmanuella Nsenbah Batu, Peter Kojo Brenya, Bright Amankwaa, Evans Asamoah Adu, Adjei Gyimah Akwasi, Roberta Yaa Asiwu
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104375
Abstract:
Background: Adoption of a life style modification is of critical importance for preventing and managing hypertension. This study determined the adherence to lifestyle modification among hypertensive clients at Juaso district hospital. Methodology: This was a descriptive cross-sectional study, conducted among hypertensive clients at Juaso district hospital, Kumasi, in the Ashanti Region of Ghana. A reviewed-structured questionnaire was used to collect data from the respondents. A total of 300 respondents were conveniently sampled for the study. Clients diagnosed of hypertension and who regularly met appointment dates at the Out Patient Department (OPD) for at least six months duration were included in this study. Statistical analysis was done using SPSS and p-value less than 0.05 was considered statistically significant. Results: The mean age (SD) of the participants was 63.6 years (±11.6) and median duration of having hypertension was 4 years. Out of the 300 participants, 72.0% of the participants were adherent to life style modification. The level of education (p < 0.0001), marital status (p < 0.0001) and duration of disease (p < 0.0001) statistically significant influenced the general rate of adherence. Participants who had secondary education [OR = 0.04 (0.005-3.1), p ≤ 0.0001)], tertiary education [OR = 0.8 (0.01-6.3), p = 0.003)], have had hypertension for a duration of 5 - 10 years [OR = 2.9 (1.5-5.8), p = 0.002)] and married [OR = 2.3 (1.1-4.9), p = 0.034)] were significantly associated with high rate of adherence to lifestyle modification. Participants who reported of being educated on the effect of smoking and alcohol consumption [OR = 2.2 (0.8-5.7), p ≤ 0.0001)] and exercise [OR = 58.9 (7.7-449.9), p ≤ 0.0001)] were significantly associated with high rate of adherence to lifestyle modification. Conclusion: The study showed that, the rate of adherence to lifestyle modification among hypertensive patients was high. Socio-demographic factors such as level of education, marital status and duration of disease significantly influenced the general rate of adherence.
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