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Search Results: 1 - 10 of 1202 matches for " Adrenal glands "
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A Case Report: A Giant Adrenal Myelolipoma
P. Shapoori
Qom University of Medical Sciences Journal , 2009,
Abstract: Background and ObjectivesAdrenal myelolipoma is a rare benign condition. Most of these tumors are diagnosed as incidental findings during imaging. The asymptomatic patient with small lesion should be followed, but the symptomatic patient with functional tumor and large lesion requires surgery .Case ReportThe 45 year-old male patient referred to the hospital. He was obese and suffering from back and left flank ache. He had also a history of hyper-lipidemia. He was sent for an Abdominal Sonogram and CT scan. Quite accidentally, a huge mass with the dimensions of 22í16cm and fat density within was observed in the right adrenal. Then, the required investigations regarding hormonal activity were conducted. Finally, due to the big size of the mass in order to prevent it from spontaneous rupture, he underwent the right adrenalectomy operation . Keywords: Adrenal Glands; Myelolipoma; Endocrine Glands.
Cirugía laparoscópica en el tratamiento de enfermedades adrenales: experiencia en 200 casos
Castillo,O.; Cortés,O.; Kerkebe,M.; Pinto,I.; Arellano,L.; Contreras,M.;
Actas Urológicas Espa?olas , 2006, DOI: 10.4321/S0210-48062006000900010
Abstract: objective: we are presenting our experience in laparoscopic adrenalectomy, after adopting the laparoscopic technique for 10 years as a primary option for suprarenal surgery. methods: we included 200 laparoscopic adrenal surgeries performed in a consecutive manner in 183 patients with surgical suprarenal pathology between november 1994 and november 2005. sixty-seven (36.6%) patients were male and 116 (63.4%) were female, with an average age of 49.1 years (age range 8 months to 78 years). results: the most frequents clinical diagnosis were hyperaldosteronism (17.5%), metastatic cancer (15.8%), pheochromocytoma (15.3%), cushing syndrome (7.1%), adrenal cyst (4.9%) and myelolipoma (2.7%). a total of 164 total adrenalectomies, 29 partial adrenalectomies and 7 marsupializations of adrenal cysts were performed. mean surgical time was 82.6 minutes (range 25 to 240 minutes) and mean hospitalization time was 2.5 days (range 1-10 days). the size of the suprarenal gland and/or tumor varied between 1 and 14 cm (average 5.6 cm). the rate of complication was 6%. in 8 of the patients, there was another laparoscopic procedure besides the adrenal surgery: cholecystectomies (2), marsupialization of a renal cyst (2), block nephrectomy (2), partial nephrectomy for a tumor (1) and pancreatic cystectomy (1). one patient underwent a right laparoscopic adrenalectomy and an ipsilateral percutaneous nephrolithotomy. conclusion: the accumulated experience with 200 laparoscopic adrenal procedures has allowed the management of endocrine pathologies, such as, aldosteroma, pheochromocytoma, cushing syndrome and rare entities, such as, cysts, myelolipomas in a suitable manner. additionally, it has permitted us to extend the benefits of a minimally invasive procedure for large adrenal masses and selected oncology cases.
Adrenalectomia laparoscópica: 10 anos de experiência
Castilho, Lísias Nogueira;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2004, DOI: 10.1590/S0004-27302004000500023
Abstract: introduction: the laparoscopic approach to the adrenal gland was first reported in 1992. since then, many publications about this issue have come from europe, japan and north america. we reviewed our 10-year experience with laparoscopic adrenal surgery. patients and methods: laparoscopic adrenalectomy was carried out in 113 patients, 77 females and 36 males, between january 1994 and january 2004. the age ranged from 1 to 76 years (43.1 ± 16.2 years). ten (8.8%) patients were 20 years old or younger, 19 (16.8%) patients had unilateral tumor larger than 4cm, 25 (22.1%) patients had body mass index > 30kg/m2, and 13 (11.5%) had had previous open upper abdominal surgery. the size of the lesion ranged from 1 to 9cm (3.3 ± 1.6cm). one hundred and sixteen operations were performed, of which 109 were unilateral and 7 were bilateral, adding up to a total of 123 adrenalectomies. among the 116 procedures, the lateral transperitoneal approach was employed in 113 cases, whereas lateral retroperitoneal approach enabled 3 adrenalectomies. results: unilateral procedures lasted 107 ± 33.7 min (45-250 min); bilateral procedures lasted 180 ± 90.6 min (100-345 min); 5 (4.3%) cases were converted to open surgery. twenty (17.7%) patients suffered complications, being 8 (7.0%) intraoperative and 12 (10.6%) postoperative complications. six (5.3%) cases were considered major complications. no deaths occurred due to the surgical procedures. blood transfusion rate was 3.5%. hospital stay was 5.7 ± 15.0 days (1-140 days). follow-up period was 23 ± 12.8 months (1-60 months) and all these patients were followed for a minimum of 6 months. conclusions: laparoscopic adrenalectomy is feasible and has excellent results in selected patients.
Effects of cold water swim stress on volumetric parameters of adrenal gland in rats
Hamidreza Mahmoudzadeh-Sagheb,Zahra Heidari,Mohammadreza Shahraki
Zahedan Journal of Research in Medical Sciences , 2011,
Abstract: Background: The adrenal gland is an essential organ in systems that are responsible for the maintenance of homeostasis during stress. The aim of this study was to examine the effects of cold water swim stress (CWSS) on the volumetric parameters of rat adrenal gland. Materials and Method: In this experimental study, 20 mature male Sprague Dawley rats, weighing 200±30 g were selected and randomly divided into two equal study and control groups (n=10). Stress was induced by forced swimming in cold water (15°C), 2 min daily for 20 days. The animals were weighed and decapitated. Their adrenal glands were excised quickly, freed of fat tissue, weighed, and fixed in Lilli’s solution and embedded in paraplast, according to routine histological procedures. Five μm sections were cut using microtome and stained by the Masson trichrome technique. Volumetric parameters of adrenal gland and its components were estimated using point counting method. The Mann Whitney-U test was employed to determine statistically significant differences between the means. Results: Results showed that cold water swim stress induced a significant reduction in body weight (p<0.01), and a significant increase in relative adrenal weight (p<0.001). The absolute volume of zona fasciculata increased significantly (p<0.05) and the volume fraction of zona reticularis decreased significantly (p<0.05) in CWSS compared to the control group. Conclusion: Cold water swim stress (CWSS) produces volumetric changes in the rat adrenal glands. Different zones of the glands respond differently to cope with this stress
P.V. Glybochko,A.A. Svistunov,A.B. Polosov. M.V. Novogilova
Saratov Journal of Medical Scientific Research , 2007,
Abstract: Long-term results of surgical treatment of 260 patients with hormonal awake tumours of adrenals are analysed. The following parameters were studied: arterial pressure in the remote periods after operation, vascular complications, necessity and a choice of hypotensive therapy in the postoperative periods, a lethality in the remote periods after operation. Analysis of efficacyy of various kinds of operative treatment in the remote postoperative periods is carried out. Also the substantiation of selection of hypotensive therapy in dependence on a kind of hormonal activity is given.
Crescimento de pacientes com hiperplasia congênita das supra-renais, forma perdedora de sal, nos dois primeiros anos de vida
Mendes-dos-Santos, Carolina T.;Lemos-Marini, Sofia H. V. de;Baptista, Maria Tereza M.;Guerra-Junior, Gil;De-Mello, Maricilda P.;Morcillo, André M.;
Revista Brasileira de Saúde Materno Infantil , 2009, DOI: 10.1590/S1519-38292009000400005
Abstract: objectives: to assess the growth and nutritional recovery of patients with the classical salt-wasting form of congenital adrenal hyperplasia in the first two years of life. methods: z scores for weight and height were calculated for 21 patients at birth, on the occasion of the first medical consultation and at one and two years of age. the concentrations of 17-hydroxyprogesterone, androstenedione and the doses of hydrocortisone prescribed at the first medical concentrations up to the age of two years were determined (at one and two years of age respectively). results: the mean age for the first medical consultation was 36.7 days. the z score for weight at birth was -0.23±1.4; on the occasion of the first consulta tion -2.31±1.3; at the age of one year -1.43±1.6 and at the age of two years -0.77± 1.3. the z score for height at birth was -0.69±2.3; on the occasion of the first consultation -1.87±1.7; at one year of age 1.68±1.1 and at two years -1.07±1.0. the difference between the scores at two years of age and on the occasion of the first medical consultation was 1.54±1.7 for weight and 0.80±1.6 for height. the mean dosage of hydrocortisone prescribed was 21.3 and 19.9 mg/m2/day for periods 1 and 2 and the concentrations (ng/dl) of 17-hydroxyprogesterone and androstenedione were 9.1 and 0.14 for period 1 and 4.4 and 0.27 for period 2. conclusions: nutritional recovery was observed to occur on treatment and, at two years of age, weight and height are normal, although below the average for the population at large.
Effects of hypoxic stress on medullary arteries of suprarenal glands
Mihalj Marija,Pilija Vladimir I.
Medicinski Pregled , 2003, DOI: 10.2298/mpns0308333m
Abstract: Introduction It is known that suprarenal glands consist of two parts: cortex and medulla. Functional properties of circulation in these two parts are still unknown. This is a very important problem, but only a few studies have dealt with it, whereas full attention should be paid to the problem in future researches. Material and methods The experiment included 100 sexually experienced male rats which were exposed to hypoxia in testing chambers imitating conditions at 7000 m above sea level. In order to study blood vessels, we used a mixture of Indian ink and 10% solution of gelatin and injected it into the left heart ventricle. Results and discussion The most outstanding finding pointed to existence of wide ischemic areas in the outer portion of zona fasciculata, along with simultaneous strong dilatation and increased number of medullary arteries. Therefore, a conclusion can be made that the number of opened medullary arteries in the suprarenal gland depends on functional conditions and needs of the organism. The method used to present our results showed that vascular network of the suprarenal glands changed dynamically under experimental conditions. Conclusion The obtained results point to functional accommodation of vascular network of suprarenal glands affected by stress, whereas medullary arteries are of predominantly functional character.
Carcinoma da glandula supra-renal
Freitas, Alexandre Coutinho Teixeira de;
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S?o Paulo) , 2007, DOI: 10.1590/S0102-67202007000300002
Abstract: background: adrenal gland neoplasm may be originated from diverse histological types. carcinomas are rare findings, and correspond to only 0,02% of all neoplasms. aim: to review the latest advances in relation to the treatment of adrenal gland carcinomas. methods: a literature review was performed using medline, text books and authors, as well as references obtained from relevant articles. conclusion: approximately 79% of adrenal gland carcinomas are functional. the most commonly secreted hormone is cortisol, which causes cushing′s syndrome. patients with non-functional lesions may complain about local growth of the lesion. this type of carcinoma is present in a series of other neoplasic syndromes of familiar origen. according to the symptoms, initial diagnostic investigation involves dosage of urinary cortisol, as well as aldosterone and renin serum levels. abdominal tomography or magnetic ressonance are first class image tests. fluorodeoxyglucose pet scan is a tool that can be used to differentiate benign and malignant lesions. fine needle biopsy is not indicated due to the high rate of complications. the choosen treatment is usually surgery with block ressection of adjacent organs if necessary. aortic and retroperitoneal lymphadenectomy should be performed. local recurrence and metastasis occur in 80% of the cases. cytoreductive surgical procedures benefit cases of advanced disease. quimiotherapy using mitotane is indicated to patients who were submitted to cytoreductive surgery, who have had local recurrence and in those with metastasis. radiotherapy is the treatment of choice in the event of bone metastasis and adjuvant treatment is used in a few cases with elevated recurrence risks. in adults, the overall average life span in 5 years varies between 10% to 35%. after curative surgery it varies between 20% to 58%.
Leiomiossarcoma primário de adrenal
Tomasich, Flávio D. Saavedra;Luz, Murilo de Almeida;Kato, Massakazu;Targa, Giovanni Zenedin;Dias, Luiz Ant?nio Negr?o;Zucoloto, Francielle Jorge;Ogata, Daniel Cury;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2008, DOI: 10.1590/S0004-27302008000900017
Abstract: leiomyosarcoma of adrenal gland is an extremely rare tumor originating from the central adrenal vein or its tributaries. patients with human immunodeficiency virus (hiv) and epstein-barr infection have a higher incidence of these tumors, but even in those, the overall incidence is very low. in this paper we report a case of a 48 year-old woman whose diagnosis was made by image exams that had suggested a mass in adrenal area. this patient was submitted to surgery for resection of the mass. the histopathologic and immunohistochemistry exams were compatible with primary leiomyosarcoma of adrenal gland. fifty-three months after adrenalectomy the patient died with recurrent disease. despite of the rarity of this tumor, leiomyosarcoma of adrenal gland has an aggressive behavior, such as the others soft tissue sarcomas. the adrenalectomy is the primary treatment, while chemotherapy or radiotherapy is not prescribed except in metastatic or bulky and not operative disease.
Hiperplasia endotelial papilífera de supra-renal: relato de caso
Nassif, Aissar E;Pozzobon, Hélio Jorge;Azevedo, édison Z.;Taguchi, Willian Setsumi;Gomes, Regina Xavier;
Revista do Colégio Brasileiro de Cirurgi?es , 2009, DOI: 10.1590/S0100-69912009000300018
Abstract: intravascular papillary endothelial hyperplasia is a benign and rare intravascular process thought to arise from an organizing thrombus. involvement of the adrenal gland is extremely rare, with only one case reported in the literature. we report a case of this vascular lesion in the adrenal gland, treated with laparoscopic adrenalectomy.
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