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Search Results: 1 - 10 of 183 matches for " Adebiyi Gbadebo Adesiyun "
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Unsupervised medical abortion with misoprostol among adolescent—what is the prospect of demedicalise abortion in sub-Saharan Africa?  [PDF]
Adebiyi Gbadebo Adesiyun, Austin Ojabo
Open Journal of Obstetrics and Gynecology (OJOG) , 2011, DOI: 10.4236/ojog.2011.14046
Abstract: Objective: To find out clinical presentation and outcome of unsupervised use of misoprostol as abortifacent among adolescents presenting with abortion complications. Methods: Case series of thirty one adolescents that presented with abortion complications following unsupervised use of misoprostol. Results: Over a period of 3 years, 31 adolescents were seen, with median age of 17 years. Twenty nine (93.5%) were unmarried and 22 (71%) were in secondary school. Pregnancy duration was 3months and above in 23 (74.2%) of the patients. The cumulative dose of misoprostol tablet ingested was 2 (400 µg) in 17 (54.8%) of the patients. Twenty three (74.2%) patients presented with incomplete abortion with mild sepsis while the remaining 8 (25.8%) patients were admitted and managed with incomplete abortion with severe sepsis. Treatments offered were manual vacuum aspiration in 23 (74.2%) patients, evacuation of retained product of conception under anaesthesia in 7 (22.6%) patients and 1 (3.2%) patient had laparotomy with uterine repair following inadvertent uterine perforation complicating curettage for incomplete abortion. Complications encountered were anaemia 67.7%, uterine perforation 3.2%, blood transfusion 9.7% and diarrhoea in 8 (25.8%) patients. Conclusion: Demedicalise abortion with misoprostol due to improper dosing protocol may be associated with incomplete abortion and its sequelae in an uninformed adolescent population. Establishment of adolescent friendly medical centre that offers post abortion care will go a long way in alleviating this problem.
Heterotopic tubal pregnancy with live twin birth complicating ovulation induction assisted cycle  [PDF]
Adebiyi Gbadebo Adesiyun, Benson Ayodele-Cole
Open Journal of Obstetrics and Gynecology (OJOG) , 2012, DOI: 10.4236/ojog.2012.23068
Abstract: Heterotopic pregnancy is an uncommon clinical entity in Nigeria even though some of the risk factors are highly prevalent in the population. We report a case of heterotopic pregnancy following ovulation induction with clomiphene citrate. A favourable outcome resulting in live twin birth was recorded despite the presence of poor clinical features that affects pregnancy and foetal outcome.
Investigation Correlates of Chlamydia Anti-Body Testing and Hysterosalpingography among Women with Tubal Infertility  [PDF]
Afolabi Korede Koledade, Adebiyi Gbadebo Adesiyun
Open Journal of Obstetrics and Gynecology (OJOG) , 2014, DOI: 10.4236/ojog.2014.416148

Background: Chlamydia trachomatis infection is an important preventable cause of infertility. In women, up to 70% of genital infection with Chlamydia trachomatis are asymptomatic. In the management of infertility patients, a lot of clinicians or centres do not routinely screen for Chlamydia trachomatis infection. Hence all patients being investigated for infertility may potentially be at risk of tubal blockage in addition to non-tubal factor aetiology. Those with primary tubal blockage also are at risk of worsening of the blockage. Objective: To determine if there is a relationship between IgG and IgM Chlamydia antibody testing (CAT) and tubal factor infertility. Design: It was a cross sectional descriptive study. Method: The sera of 400 consecutive consenting infertile patients presenting to the gynaecological clinic of the Ahmadu Bello University Teaching Hospital, Zaria, Northern Nigeria were tested for Chlamydia antibodies using ELISA IgG and IgM kits produced by Diagnostic Automation, Inc., 23961 Craftsman Road, Suite D/E/F, Calabasas, CA 91302, USA. Results: Up to 264 (66%) of the patients had tubal factor, 64 (16%) had uterine, 56 (14%) had ovarian, 50 (12.5%) had male while 40 (10%) had others. The causative factors were not mutually exclusive. The sero-prevalence of IgG and IgMChlamydia trachomatis

Intrauterine diagnosis of proximal jejunal atresia in a neonate conceived by assisted conception technique: a case report  [PDF]
Adebiyi Gbadebo Adesiyun, Modupeola Omotara Samaila, Ayodele Cole Benson
Open Journal of Obstetrics and Gynecology (OJOG) , 2011, DOI: 10.4236/ojog.2011.13021
Abstract: Jejunal atresia is an entity within an array of congenital intestinal anomalies. We present a case of antepartum diagnosis of proximal jejunal atresia in a baby conceived through assisted conception.
Awareness and perception of assisted reproductive technology practice amongst women with infertility in Northern Nigeria  [PDF]
Adebiyi Gbadebo Adesiyun, Nkeiruka Ameh, Solomon Avidime, Abdulsalam Muazu
Open Journal of Obstetrics and Gynecology (OJOG) , 2011, DOI: 10.4236/ojog.2011.13027
Abstract: Background: Involuntary infertility is a tragedy in most African setting. This is due to premium placed on fertility as a result of roles children fulfill in the family and the society. Aetiologic factors of infertility in sub-Saharan Africa are mostly infection related and they are mainly associated with poor treatment outcome to conventional non assisted conception technique. Objective: To evaluate the level of awareness and perception of assisted conception treatment among women attending fertility clinic. Methods: A descriptive cross-sectional study. Results: One hundred and ninety six women attending fertility clinic were interviewed. Mean age was 34.8year and mean duration of infertility of 4.1 years. Of the 196 infertile women interviewed, 150 (76.5%) have heard of Assisted Reproductive Technology treatment. Sources of information were mainly family relation (46%) and friends (28.7%). Knowledge on some of Assisted Reproductive Technology practices showed that 50.7% were aware that the treatment could fail, 36.8% knew it could be applied for male infertility treatment, 9.3% and 18.7% respectively are aware that donor oocyte and sperm could be used for treatment. Perception on babies conceived from assisted conception treatment revealed that 52% of patients interviewed could not comment if they are normal and natural babies. Majority of patients could not affirm if they will agree to the use of donor gamete or zygote for their treatment. Conclusion: Awareness of assisted conception treatment was high, however knowledge on specifics of treatment was low and perception on some of the practices was unfavorable. Sensitization of the public will help overcome some beliefs that may be at tangent to some practices of assisted conception.
Clinical and investigative correlates of etiologic risk factors on treatment outcome of intrauterine adhesion in women with infertility: A descriptive study  [PDF]
Adebiyi Gbadebo Adesiyun, Marliya S. Zayyan, Anthony Eka, Ijeoma Ozed Williams, Austin Ojabo
Open Journal of Obstetrics and Gynecology (OJOG) , 2014, DOI: 10.4236/ojog.2014.42017

Background: Intrauterine adhesion is a clinical entity that may present with subfertility. However, outcome of management depends on severity of intrauterine adhesion and type of treatment intervention employed. Objective: To evaluate clinical and investigative correlation of etiologic risk factors of intrauterine adhesion on fertility and pregnancy outcome following treatment. Patients and Methods: A 5 years prospective observational study. Treatment employed includes transvaginal blind intrauterine adhesiolysis, insertion of inert intrauterine device or inflated Foley’s catheter balloon and oestrogen therapy. Inclusion criteria are intrauterine adhesion as the only identifiable cause of infertility and post treatment follows up for at least a year. Results: Over a period of 5 years, 63 patients with mean age of 31.6 years and age range of 21 to 42 years were managed. Etiologic risk factors were dilatation and curettage 33 (52.4%), vacuum aspiration 13 (20.6%), myomectomy 11 (17.5%) and caesarean section in 6 (9.5%) patients. Of the 63 patients, 28 conceived giving a pregnancy rate of 44.4%. Nine out of the 28 patients that conceived had miscarriage, giving a miscarriage rate of 32.1%. The highest pregnancy rate and lowest miscarriage rate were recorded in the subgroup that had vacuum aspiration as their etiologic risk factor. Late pregnancy complications encountered are preterm contractions 5 (26.3%), placenta praevia 4 (21.1%), morbidly adherent placenta 5 (26.3%) and preterm delivery in 2 (10.5%) patients. Route of delivery was per vaginum in 13 (68.4%) patients and by caesarean section in 6 (31.6%) patients. Live birth rate was 89.5% (17/19 deliveries). There was no maternal mortality recorded. Conclusion: Compared to other risk factors, uterine vacuum aspiration was associated with higher fertility rate and better pregnancy outcome

Term Gravid Uterus as a Content of Congenital Umbilical Hernia—A Complication in a Multigravida That Presented in Labour  [PDF]
Adebiyi Gbadebo Adesiyun, Nkeiruka Ameh, Hajaratu Umar-Sullyman, Solomon Avidime, Garba Alkali, Fadimatu Bakari, Rabiatu Aliyu
Case Reports in Clinical Medicine (CRCM) , 2015, DOI: 10.4236/crcm.2015.41002
Complications arising from neglected umbilical hernia are not uncommon in pregnancy, more especially in developing countries with characteristically poor health seeking behaviour and less encouraging attitude towards surgical intervention for un-complicated medical conditions. The report is on a 34-year-old para 8 who presented with prolonged labour and an irreducible herniated gravid uterus complicating a neglected congenital umbilical hernia. The patient was resuscitated. She had spontaneous vaginal delivery while preparation was being made for an elective caesarean section.
Ruptured tubal hydatidiform mole
Modupeola Omotara Samaila,Adebiyi Gbadebo Adesiyun,Calvin Bifam
Journal of the Turkish-German Gynecological Association , 2009,
Abstract: Objective: Ruptured ectopic gestation is a life threatening medical emergency especially in developing countries. However, the occurrence of hydatidiform mole in ruptured tubal pregnancy is uncommon. Material and Methods: A consecutive analysis of patients with hydatidiform mole in ruptured tubal gestation over a 9-year period in a tertiary hospital. Results: Of a total of 101 females with ectopic gestations, only five had ruptured tubal hydatidiform mole. The ages ranged from 20-37years and they all presented with acute abdominal symptoms which necessitated emergency surgical intervention. Intra-operative findings revealed ruptured/ leaking tubal gestation. The excised tissue specimens showed hydatidiform mole characterized by circumferential trophoblastic proliferation, hydropic degeneration and stromal karyorrhexis. Patients’ serial HCG levels were monitored before discharge. Conclusion: Ruptured tubal hydatidiform mole is uncommon and strict histologic criteria are important in diagnosis. Serial HCG levels must be monitored in individual patients to forestall development of malignant trophoblastic disease.
Postpartum Ovarian Vein Thrombosis: Incidental Diagnosis at Surgery
Adebiyi Gbadebo Adesiyun,Modupeola O. A. Samaila,Austin Ojabo
Case Reports in Obstetrics and Gynecology , 2014, DOI: 10.1155/2014/898342
Abstract: Ovarian vein thrombosis is a rare clinical entity that may present in the puerperium. We report the clinical outcomes of two cases of postpartum ovarian vein thrombosis, incidentally diagnosed at laparotomy in 16-year-old and 23-year-old females. They had preoperative diagnosis of torsion tuboovarian mass and twisted pedunculated uterine fibroid, respectively. Both patients had transection and ligation of right thrombosed ovarian vein. Postoperative management included a week course of anticoagulant, antibiotics and analgesia. Postpartum ovarian vein thrombosis is a diagnosis of exclusion in the puerperium and a high index of suspicion will reduce associated morbidity and mortality. 1. Introduction Postpartum ovarian vein thrombosis (POVT) is a rare puerperal complication, with an incidence of 1/600 and 1/2000 deliveries [1]. Its occurrence in nonpregnant patients has seldom been reported [2]. Three factors important in the pathogenesis of thrombosis are blood flow stasis, endothelial injury and hypercoagulability states [3]. The postpartum period is known to facilitate the occurrence of blood stasis due to collapse of the ovarian vein that was hitherto three times larger with sixty times increase in blood flow during pregnancy [3]. A physiologic hypercoagulability resulting from increased production of clotting factors I, II, VII, X and XI and increase platelet adhesiveness are also seen in the puerperium [3]. Endothelial injury is usually triggered by exogenous factors like intrauterine and urinary tract infection [3]. The aim of this paper is to present the clinical outcomes of two cases of postpartum ovarian vein thrombosis diagnosed incidentally at laparatomy. 2. Case 1 A 16-year-old para 2 female presented with 2 days history of right sided lower abdominal pain with associated fever. Five days prior to presentation, she had boy by a traditional birth attendant at home. Examination revealed an ill-looking woman with a temperature of 38.4°C. The uterus was consistent with sixteen weeks pregnancy size. Ultrasound scan showed a right tuboovarian mass that measured 7.2?cm × 6.0?cm. The uterine cavity was empty. A clinical diagnosis of right tuboovarian mass with torsion was made. Packed cell volume was 31% and there was leucocytosis of 13.0 × 109/L. She had laparotomy. Intraoperatively, a thrombosed right ovarian vein was found with oedematous right adnexium (Figure 1). She had transection and ligation of the right ovarian vein. Postoperatively, she was placed on antibiotics (metronidazole and ceftriaxone), analgesia (pentazocine), and subcutaneous
Cutaneous umbilical metastases in post-menopausal females with gynaecological malignancies
Modupeola Omotara Samaila,Adebiyi Gbadebo Adesiyun,Garba Dahiru Waziri,Korede Afolabi Koledade
Journal of the Turkish-German Gynecological Association , 2012,
Abstract: Gynaecological malignancies frequently metastasize to contiguous structures, internal organs and bones. Cutaneous metastasis as a primary or recurrent presentation of these malignancies is rare and only a few cases have been reported in the literature. A twenty year (1991-2010) retrospective search for umbilical metastasis from gynaecological malignancies in our departmental case records showed only four cases. Four post-menopausal females presented with painful cutaneous umbilical (Sister Joseph’s) nodules. The clinical examinations of all four patients revealed well delineated nodules of varying sizes and degrees of ulceration. Other findings were matted axillary and inguinal lymph node enlargement, intra-abdominal and pelvic masses, vaginal discharge and vaginal bleeding. Incisional tissue biopsies from the nodules were processed in paraffin wax and stained with haematoxylin and eosin. Histology of the sections showed pigmented skin overlying metastatic malignant tumours consistent with adenocarcinoma from the endometrium and ovary in three cases, and squamous cell carcinoma, large cell keratinizing from the cervix uteri in the fourth case. Gynaecological cancers have a global spread and varied geographic distribution. Cervical cancer is the commonest in our setting and patients often present to hospital with advanced stage disease. Ovarian and endometrial cancers are infrequent and their diagnosis may be delayed by non- specificity of presenting clinical symptoms from other benign tumours at these sites. Although umbilical metastasis is commonly associated with gastro-intestinal malignancies, its presence may be the first harbinger of occult gynaecologic cancer.
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