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Search Results: 1 - 10 of 327250 matches for " Adalgisa S.;Matos "
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Effect of host-related factors on the intensity of liver fibrosis in patients with chronic hepatitis C virus infection
Costa, Luciano Bello;Ferraz, Maria Lucia Gomes;Perez, Renata M.;Ferreira, Adalgisa S.;Matos, Carla Adriana L.;Lanzoni, Valéria P.;Silva, Ant?nio Eduardo;
Brazilian Journal of Infectious Diseases , 2002, DOI: 10.1590/S1413-86702002000500002
Abstract: there is increasing interest in the identification of factors associated with liver disease progression in patients infected with hepatitis c virus (hcv). we assessed host-related factors associated with a histologically advanced stage of this disease and determined the rate of liver fibrosis progression in hcv-infected patients. we included patients submitted to liver biopsy, who were anti-hcv and hcv rna positive, who showed a parenteral risk factor (blood transfusion or intravenous drug use), and who gave information about alcohol consumption.patients were divided into two groups for analysis: group 1 - grades 0 to 2; group 2 - grades 3 to 4. the groups were compared in terms of sex, age at the time of infection, estimated duration of infection and alcoholism. the rate of fibrosis progression (index of fibrosis) was determined based on the relationship between disease stage and duration of infection (years). logistic regression analysis revealed that age at the time of infection (p<0.01; 95% ci 1.06-1.22) and the duration of infection (p<0.01; 95% ci 1.06-1.32) were independently associated with a more advanced stage of hepatitis c. the median index of fibrosis was 0.14 for the group as a whole. a significant difference in the index of fibrosis was observed between patients aged < 40 years at infection (median = 0.11) and patients aged 3 40 years (median = 0.47). the main factors associated with a more rapid fibrosis progression were age at the time of infection and the estimated duration of infection. patients who acquired hcv after 40 years of age showed a higher rate of fibrosis progression.
PREVALêNCIA DE DOR MUSCULOESQUELéTICA EM IDOSOS QUE PRATICAM ATIVIDADE FíSICA
Adalgisa Pedersen Alves,Caroline Cabezudo Medeiros,Caroline de Andrade Bacchi,Mauro Matos
Ciência & Saúde , 2009,
Abstract:
Utopia e distopia nella prosa di Vladimir Odoevsky. Alcuni indizi nelle opere giovanili
Adalgisa Mingati
Studi Slavistici , 2009,
Abstract: Utopia and Dystopia in V.F. Odoevsky's Fiction: some Clues in his Early Writing In Russian literature utopia and dystopia are often tightly interwoven. Also in the work of V.F. Odoevsky (1804-1869) some texts commonly de ned as ‘utopian’ are in fact intertwined with a dark irony that seemingly leaves very little room for hope. However, Odoevsky’s dystopias should never be taken literally, on the contrary it is necessary to consider the speci c cultural context in which they are placed, i.e., the paradoxical debate inspired by Menippean satire. The purpose of this paper is to identify in the writer’s two early texts, The Old People, or The Isle of Panchaia (1824) and Two Days in the Life of the Terrestrial Globe (1828), the presence of narrative elements which can be attributed to the utopian/dystopian topos and to de ne their principal features and probable derivative texts. In so doing, all the clues indispensable for an exhaustive reconstruction of the artistic process will be brought together, a process which, at the end of the 1830s, led to the genesis of two of Odoevsky’s famous dystopias set in the frame novel Russian Nights (1844), i.e, The Last Suicide and The City Without a Name ( rst published in 1839), as well as the un nished The Year 4338 (1835-40).
O ensino do português a estrangeiros na Faculdade de Letras da Universidade do Porto
Sérgio Matos
Linguística : Revista de Estudos Linguísticos da Universidade do Porto , 2007,
Abstract:
Phylogeography and Taxonomy of Trypanosoma brucei
Oliver Balmer equal contributor ,Jon S. Beadell equal contributor,Wendy Gibson,Adalgisa Caccone
PLOS Neglected Tropical Diseases , 2011, DOI: 10.1371/journal.pntd.0000961
Abstract: Background Characterizing the evolutionary relationships and population structure of parasites can provide important insights into the epidemiology of human disease. Methodology/Principal Findings We examined 142 isolates of Trypanosoma brucei from all over sub-Saharan Africa using three distinct classes of genetic markers (kinetoplast CO1 sequence, nuclear SRA gene sequence, eight nuclear microsatellites) to clarify the evolutionary history of Trypanosoma brucei rhodesiense (Tbr) and T. b. gambiense (Tbg), the causative agents of human African trypanosomosis (sleeping sickness) in sub-Saharan Africa, and to examine the relationship between Tbr and the non-human infective parasite T. b. brucei (Tbb) in eastern and southern Africa. A Bayesian phylogeny and haplotype network based on CO1 sequences confirmed the taxonomic distinctness of Tbg group 1. Limited diversity combined with a wide geographical distribution suggested that this parasite has recently and rapidly colonized hosts across its current range. The more virulent Tbg group 2 exhibited diverse origins and was more closely allied with Tbb based on COI sequence and microsatellite genotypes. Four of five COI haplotypes obtained from Tbr were shared with isolates of Tbb, suggesting a close relationship between these taxa. Bayesian clustering of microsatellite genotypes confirmed this relationship and indicated that Tbr and Tbb isolates were often more closely related to each other than they were to other members of the same subspecies. Among isolates of Tbr for which data were available, we detected just two variants of the SRA gene responsible for human infectivity. These variants exhibited distinct geographical ranges, except in Tanzania, where both types co-occurred. Here, isolates possessing distinct SRA types were associated with identical COI haplotypes, but divergent microsatellite signatures. Conclusions/Significance Our data provide strong evidence that Tbr is only a phenotypic variant of Tbb; while relevant from a medical perspective, Tbr is not a reproductively isolated taxon. The wide distribution of the SRA gene across diverse trypanosome genetic backgrounds suggests that a large amount of genetic diversity is potentially available with which human-infective trypanosomes may respond to selective forces such as those exerted by drugs.
Temporal stability of Glossina fuscipes fuscipes populations in Uganda
Richard Echodu, Jon S Beadell, Loyce M Okedi, Chaz Hyseni, Serap Aksoy, Adalgisa Caccone
Parasites & Vectors , 2011, DOI: 10.1186/1756-3305-4-19
Abstract: Results of an AMOVA indicated that time of sampling did not explain a significant proportion of the variance in allele frequencies observed across all samples. Estimates of differentiation between samples from a single population ranged from approximately 0 to 0.019, using Jost's DEST. Effective population size estimates using momentum-based and likelihood methods were generally large. We observed significant change in mitochondrial haplotype frequencies in just one population, located along the zone of contact. The change in haplotypes was not accompanied by changes in microsatellite frequencies, raising the possibility of asymmetric mating compatibility in this zone.Our results suggest that populations of G. f. fuscipes were stable over the 8-12 generations studied. Future studies should aim to reconcile these data with observed seasonal fluctuations in the apparent density of tsetse.Tsetse flies, Glossina spp (Diptera: Glossinidae) transmit several species of pathogenic trypanosomes causing Human African Trypanosomiasis (HAT) and African Animal Trypanosomiasis (AAT). HAT affects human welfare directly through the chronic and acute forms of the disease caused by Trypanosoma brucei gambiense and T. b. rhodesiense respectively. AAT, on the other hand, stands as a major obstacle to the development of more efficient and sustainable livestock production systems in tsetse-infested areas [1]. A major challenge to controlling HAT is lack of suitable prophylactic drugs and vaccines against trypanosomiasis. Furthermore, chemotherapeutic agents for treatment of HAT are expensive, difficult to administer in remote areas and exhibit poor safety profiles. Consequently, vector control remains a viable alternative for large-scale control of trypanosomiasis.Understanding tsetse population dynamics is critical for determining which control strategy is most appropriate (e.g., suppression, eradication), for choosing the best method for enacting that strategy (e.g., traps, insecticide
Development of plurimetallic electrocatalysts prepared by decomposition of polymeric precursors for EtOH/O2 fuel cell
Palma, Lívia M.;Almeida, Thiago S.;Andrade, Adalgisa R. de;
Journal of the Brazilian Chemical Society , 2012, DOI: 10.1590/S0103-50532012000300024
Abstract: this work aimed to develop plurimetallic electrocatalysts composed of pt, ru, ni, and sn supported on c by decomposition of polymeric precursors (dpp), at a constant metal:carbon ratio of 40:60 wt.%, for application in direct ethanol fuel cell (defc). the obtained nanoparticles were physico-chemically characterized by x-ray diffraction (xrd) and energy dispersive x-ray spectroscopy (edx). xrd results revealed a face-centered cubic crystalline pt with evidence that ni, ru, and sn atoms were incorporated into the pt structure. electrochemical characterization of the nanoparticles was accomplished by cyclic voltammetry (cv) and chronoamperometry (ca) in slightly acidic medium (0.05 mol l-1 h2so4), in the absence and presence of ethanol. addition of sn to ptruni/c catalysts significantly shifted the ethanol and co onset potentials toward lower values, thus increasing the catalytic activity, especially for the quaternary composition pt64sn15ru13ni8/c. electrolysis of ethanol solutions at 0.4 v vs. rhe allowed determination of acetaldehyde and acetic acid as the main reaction products. the presence of ru in alloys promoted formation of acetic acid as the main product of ethanol oxidation. the pt64sn15ru13ni8/c catalyst displayed the best performance for defc.
Effect of solvent on the preparation and characterization of DSA?-type anodes containing RuO2-TiO2-SnO2
Coteiro, Roberta D.;Teruel, Fernando S.;Ribeiro, Josimar;Andrade, Adalgisa R. de;
Journal of the Brazilian Chemical Society , 2006, DOI: 10.1590/S0103-50532006000400020
Abstract: anodes containing ruthenium, titanium, and tin oxides supported on metallic ti were prepared by thermal decomposition of precursor salts in order to investigate the effect that changing the solvent (from hcl/h2o to isopropanol) would have on the real composition of the mixed oxide electrodes. the precursor solutions and their mixtures were analyzed by uv-vis spectrophotometry. coatings morphology and composition were analyzed by scanning electronic microscopy (sem) and energy dispersive x-ray (edx). determination of the electrochemically active area and electrode stability was performed by voltammetric characterization (1.0 mol l-1 hclo4) and service life (sl) tests, respectively. electrodes prepared from isopropanol showed excellent agreement between the nominal and experimental composition and they presented higher electrochemically active area and better stability when compared to those prepared in the presence of hcl. preparation of the precursor mixture in isopropanol increases ruo2-tio2-sno2 electrodes service life.
Febre tifóide: recaída por resistência antimicrobiana. Relato de caso
Alecrim Wilson Duarte,Loureiro Adalgisa Camara de Sá Peixoto,Moraes Ricardo Silva,Monte Rossicleia Lins
Revista da Sociedade Brasileira de Medicina Tropical , 2002,
Abstract: Relatamos pela primeira vez na Amaz nia Brasileira um paciente com febre tifóide, com resistência clínica e laboratorial ao cloranfenicol, droga de escolha para esta doen a em nossa regi o. A recaída foi observada no 7° dia após o término do tratamento e a paciente foi tratada com ciprofloxacina.
Effect of host-related factors on the intensity of liver fibrosis in patients with chronic hepatitis C virus infection
Costa Luciano Bello,Ferraz Maria Lucia Gomes,Perez Renata M.,Ferreira Adalgisa S.
Brazilian Journal of Infectious Diseases , 2002,
Abstract: There is increasing interest in the identification of factors associated with liver disease progression in patients infected with hepatitis C virus (HCV). We assessed host-related factors associated with a histologically advanced stage of this disease and determined the rate of liver fibrosis progression in HCV-infected patients. We included patients submitted to liver biopsy, who were anti-HCV and HCV RNA positive, who showed a parenteral risk factor (blood transfusion or intravenous drug use), and who gave information about alcohol consumption.Patients were divided into two groups for analysis: group 1 - grades 0 to 2; group 2 - grades 3 to 4. The groups were compared in terms of sex, age at the time of infection, estimated duration of infection and alcoholism. The rate of fibrosis progression (index of fibrosis) was determined based on the relationship between disease stage and duration of infection (years). Logistic regression analysis revealed that age at the time of infection (P<0.01; 95% CI 1.06-1.22) and the duration of infection (P<0.01; 95% CI 1.06-1.32) were independently associated with a more advanced stage of hepatitis C. The median index of fibrosis was 0.14 for the group as a whole. A significant difference in the index of fibrosis was observed between patients aged < 40 years at infection (median = 0.11) and patients aged > or = 40 years (median = 0.47). The main factors associated with a more rapid fibrosis progression were age at the time of infection and the estimated duration of infection. Patients who acquired HCV after 40 years of age showed a higher rate of fibrosis progression.
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